Understanding the genetic architecture of Alzheimer’s Disease and Related Dementias
Explore the ADSP Dataset through the NIAGADS Data Discovery Portal
Powered by Gen3, the Data Discovery Portal, now in beta allows researchers to view summary information about cohorts, phenotypes, and available genetic data for the ADSP.

Available Data
For detailed information about the ADSP dataset including release notes and file manifests, or to apply for access to the dataset, go to the ADSP Umbrella Dataset page on NIAGADS DSS by clicking the button below.
*ADSP data is shared via NIAGADS DSS

Explore genomic variants identified in the ADSP dataset with Varixam.
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Latest News
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June 4, 2025
NIH Seeks Public Input on Responsible Development of Innovative AI Tools
NIH is committed to advancing novel AI approaches that have the potential to accelerate research and improve the health of the public. As such, NIH is seeking input from the public on how to develop and share... -
April 17, 2025
Whole Genome Sequencing of Over 13,000 Diverse Individuals Reveals Shared and Distinct Genetic Associations With Alzheimer’s Disease Across Subpopulations
Dr. Wan-Ping Lee leads a study investigating genetic associations with Alzheimer’s Disease (AD) within and across African American, Hispanic, and Non-Hispanic White ancestry groups, spanning 13,371 individuals. Here we highlight some key methods and results from this... -
December 20, 2024
ADSP Phenotype Harmonization Consortium Release 3 is Out!
The third release from the Alzheimer’s Disease Sequencing Project Phenotype Harmonization Consortium (ADSP-PHC), which includes harmonized phenotypes ADSP participants with sequencing, is available in the ADSP Umbrella Dataset (NG00067v15). Existing users with approval for NG00067 will have...