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2021

2021,  
European journal of neurology

Clinical, pathological and genetic characteristics of Perry disease-new cases and literature review.

Dulski, J., et al.
2021,  
Molecular neurodegeneration

TDP-43 Pathology in Alzheimer's Disease.

Meneses, A., et al.
2021,  
Proceedings of the National Academy of Sciences of the United States of America

Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer's disease-associated genes.

Moulton, MJ., et al.
2021,  
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine

Interpretable temporal graph neural network for prognostic prediction of Alzheimer's disease using longitudinal neuroimaging data.

Kim, M., et al.
2021,  
Nature aging

Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease.

Fang, J., et al.
2021,  
Autophagy

Loss-of-function mutation in VCP mimics the characteristic pathology as in FTLD-TARDBP.

Wani, A.
2021,  
American journal of human genetics

Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics.

He, Z., et al.
2021,  
Translational psychiatry

Genetically regulated expression in late-onset Alzheimer's disease implicates risk genes within known and novel loci.

Chen, H., et al.
2021,  
Diagnostics (Basel, Switzerland)

Integrated Genomic, Transcriptomic and Proteomic Analysis for Identifying Markers of Alzheimer's Disease.

Madrid, L., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype.

Guo, J., et al.
2021,  
NeuroImage

Multi-vendor and multisite evaluation of cerebrovascular reactivity mapping using hypercapnia challenge.

Liu, P., et al.
2021,  
Nature communications

A deep learning framework identifies dimensional representations of Alzheimer's Disease from brain structure.

Yang, Z., et al.
2021,  
Nature aging

Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology.

Dehkordi, SK., et al.
2021,  
Acta neuropathologica

Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids.

Zhao, J., et al.
2021,  
IEEE transactions on bio-medical engineering

Improved Prediction of Cognitive Outcomes via Globally Aligned Imaging Biomarker Enrichments Over Progressions.

Lu, L., et al.
2021,  
Proceedings of SPIE--the International Society for Optical Engineering

Alzheimer's Disease Classification Accuracy is Improved by MRI Harmonization based on Attention-Guided Generative Adversarial Networks.

Sinha, S., et al.
2021,  
Alzheimer's research & therapy

Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer's disease.

Park, YH., et al.
2021,  
Alzheimer's research & therapy

Serum zinc levels and in vivo beta-amyloid deposition in the human brain.

Kim, JW., et al.
2021,  
The Journal of clinical investigation

Recipient APOL1 risk alleles associate with death-censored renal allograft survival and rejection episodes.

Zhang, Z., et al.
2021,  
Briefings in bioinformatics

Integrative-omics for discovery of network-level disease biomarkers: a case study in Alzheimer's disease.

Xie, L., et al.
2021,  
Neuron

Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors.

Lagomarsino, VN., et al.
2021,  
Translational psychiatry

A missense variant in SHARPIN mediates Alzheimer's disease-specific brain damages.

Park, JY., et al.
2021,  
Journal of neuroimaging : official journal of the American Society of Neuroimaging

Prevalence of incidental brain MRI findings of clinical relevance in a diverse Hispanic/Latino population.

Ivanovic, V., et al.
2021,  
Nature communications

Author Correction: Regulation of local GTP availability controls RAC1 activity and cell invasion.

Bianchi-Smiraglia, A., et al.
2021,  
Analytical chemistry

JUMPt: Comprehensive Protein Turnover Modeling of In Vivo Pulse SILAC Data by Ordinary Differential Equations.

Chepyala, SR., et al.
2021,  
Molecular cell

Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy

2021,  
Health promotion international

Use of Korean dramas to facilitate precision mental health understanding and discussion for Asian Americans.

Ta Park, VM., et al.
2021,  
Acta neuropathologica

HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing.

Bampton, A., et al.
2021,  
Cells

KYNA/Ahr Signaling Suppresses Neural Stem Cell Plasticity and Neurogenesis in Adult Zebrafish Model of Alzheimer's Disease.

Siddiqui, T., et al.
2021,  
Alzheimer's research & therapy

BMI1 is associated with CS8F amyloid-β and rates of cognitive decline in Alzheimer's disease.

Kim, JP., et al.
2021,  
Genome research

Bayesian estimation of cell type-specific gene expression with prior derived from single-cell data.

Wang, J., et al.
2021,  
Bioinformatics (Oxford, England)

Identification of cell-type-specific marker genes from co-expression patterns in tissue samples.

Qiu, Y., et al.
2021,  
Molecular psychiatry

Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease.

DeMichele-Sweet, MAA., et al.
2021,  
Molecular psychiatry

The acute phase protein lactoferrin is a key feature of Alzheimer's disease and predictor of Aβ burden through induction of APP amyloidogenic processing.

Tsatsanis, A., et al.
2021,  
Molecular psychiatry

Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease.

Panitch, R., et al.
2021,  
Genes & nutrition

Mendelian randomization to evaluate the effect of plasma vitamin C levels on the risk of Alzheimer's disease.

Liu, H., et al.
2021,  
Nature aging

Effect of APOE alleles on the glial transcriptome in normal aging and Alzheimer's disease.

Serrano-Pozo, A., et al.
2021,  
Nature communications

Regulation of local GTP availability controls RAC1 activity and cell invasion.

Bianchi-Smiraglia, A., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants.

Damotte, V., et al.
2021,  
STAR protocols

Preparation of single cell suspensions enriched in mouse brain vascular cells for single-cell RNA sequencing.

Yamazaki, A., et al.
2021,  
Nature reviews. Neurology

The human connectome in Alzheimer disease - relationship to biomarkers and genetics.

Yu, M., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Alzheimer's disease alters oligodendrocytic glycolytic and ketolytic gene expression.

Saito, ER., et al.
2021,  
Nature neuroscience

Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders.

Yang, C., et al.
2021,  
bioRxiv : the preprint server for biology

Weakly activated core inflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer's disease.

Li, F., et al.
2021,  
Nature communications

Large scale enzyme based xenobiotic identification for exposomics.

Liu, KH., et al.
2021,  
Bioinformatics (Oxford, England)

Modeling multifunctionality of genes with secondary gene co-expression networks in human brain provides novel disease insights.

Sánchez, JA., et al.
2021,  
American journal of epidemiology

A Robust Test for Additive Gene-Environment Interaction Under the Trend Effect of Genotype Using an Empirical Bayes-Type Shrinkage Estimator.

Sanyal, N., et al.
2021,  
Annals of neurology

Polygenic Risk Score for Alzheimer's Disease in Caribbean Hispanics.

Sariya, S., et al.
2021,  
Cell systems

Dysregulation of the secretory pathway connects Alzheimer's disease genetics to aggregate formation.

Kuo, C., et al.
2021,  
Alzheimer's research & therapy

Leukotriene receptor antagonist use and cognitive decline in normal cognition, mild cognitive impairment, and Alzheimer's dementia.

Xiong, LY., et al.
2021,  
Acta neuropathologica communications

Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study.

Dugan, AJ., et al.
2021,  
Translational psychiatry

Cortical structure and the risk for Alzheimer's disease: a bidirectional Mendelian randomization study.

Wu, B., et al.
2021,  
medRxiv : the preprint server for health sciences

Olfactory Bulb and Amygdala Gene Expression Changes in Subjects Dying with COVID-19.

Piras, IS., et al.
2021,  
Science translational medicine

In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer's disease pathology and cognitive decline.

Jacobs, HIL., et al.
2021,  
Alzheimer's research & therapy

Herpesvirus infections and Alzheimer's disease: a Mendelian randomization study.

Huang, S., et al.
2021,  
Biomedicines

Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer's and Parkinson's Diseases.

Lam, S., et al.
2021,  
Molecular psychiatry

MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis.

Cao, J., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Midlife vascular risk factors and risk of incident dementia: Longitudinal cohort and Mendelian randomization analyses in the UK Biobank.

Malik, R., et al.
2021,  
Nature genetics

A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease.

Wightman, DP., et al.
2021,  
Science translational medicine

APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia.

Liu, C., et al.
2021,  
PLoS genetics

Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences.

Zhan, L., et al.
2021,  
BMC bioinformatics

A pipeline for RNA-seq based eQTL analysis with automated quality control procedures.

Wang, T., et al.
2021,  
Circulation. Cardiovascular imaging

Progress and Research Priorities in Imaging Genomics for Heart and Lung Disease: Summary of an NHLBI Workshop.

Nayor, M., et al.
2021,  
Translational neurodegeneration

Predictability of polygenic risk score for progression to dementia and its interaction with APOE ε4 in mild cognitive impairment.

Pyun, J., et al.
2021,  
Genes

Advances in Genetic and Molecular Understanding of Alzheimer's Disease.

Ibanez, L., et al.
2021,  
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

Associations Between Loneliness, Reading Ability and Episodic Memory in Non-Hispanic Black and White Older Adults.

Sol, K., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Plasma p-tau181, p-tau217, and other blood-based Alzheimer's disease biomarkers in a multi-ethnic, community study.

Brickman, AM., et al.
2021,  
Environmental health perspectives

Utilizing a Biology-Driven Approach to Map the Exposome in Health and Disease: An Essential Investment to Drive the Next Generation of Environmental Discovery.

Chung, MK., et al.
2021,  
Neurobiology of aging

Linkage of Alzheimer disease families with Puerto Rican ancestry identifies a chromosome 9 locus.

Rajabli, F., et al.
2021,  
Nature genetics

Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer's disease.

Morabito, S., et al.
2021,  
Nature chemistry

SARS-CoV-2 simulations go exascale to predict dramatic spike opening and cryptic pockets across the proteome.

Zimmerman, MI., et al.
2021,  
Medical image analysis

A structural enriched functional network: An application to predict brain cognitive performance.

Kim, M., et al.
2021,  
Nature methods

QSIPrep: an integrative platform for preprocessing and reconstructing diffusion MRI data.

Cieslak, M., et al.
2021,  
Cell reports

Neuronal VCP loss of function recapitulates FTLD-TDP pathology.

Wani, A., et al.
2021,  
Molecular psychiatry

Older molecular brain age in severe mental illness.

Lin, C., et al.
2021,  
BMC medicine

Investigating causal relationships between exposome and human longevity: a Mendelian randomization analysis.

Huang, S., et al.
2021,  
Nature communications

Identifying individuals with high risk of Alzheimer's disease using polygenic risk scores.

Leonenko, G., et al.
2021,  
Cell reports methods

Model-based assessment of mammalian cell metabolic functionalities using omics data.

Richelle, A., et al.
2021,  
Translational psychiatry

Heterogeneous effects of genetic risk for Alzheimer's disease on the phenome.

Wu, HM., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.

Griswold, AJ., et al.
2021,  
STAR protocols

Generation and validation of APOE knockout human iPSC-derived cerebral organoids.

Martens, YA., et al.
2021,  
Cardiovascular research

New biomarkers from multiomics approaches: improving risk prediction of atrial fibrillation.

Kornej, J., et al.
2021,  
Journal of medical Internet research

Association Between the Digital Clock Drawing Test and Neuropsychological Test Performance: Large Community-Based Prospective Cohort (Framingham Heart Study).

Yuan, J., et al.
2021,  
Journal of medical Internet research

Association of Habitual Physical Activity With Home Blood Pressure in the Electronic Framingham Heart Study (eFHS): Cross-sectional Study.

Sardana, M., et al.
2021,  
Nature neuroscience

Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease.

Zalocusky, KA., et al.
2021,  
Scientific reports

Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration.

Zhou, L., et al.
2021,  
STAR protocols

Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons.

Li, A., et al.
2021,  
Molecular psychiatry

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.

de las Fuentes, L., et al.
2021,  
Stroke

Autonomic Imbalance and Risk of Dementia and Stroke: The Framingham Study.

Weinstein, G., et al.
2021,  
Nature communications

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.

de Rojas, I., et al.
2021,  
Nature

Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy.

Da Mesquita, S., et al.
2021,  
Medical image analysis

Predicting future cognitive decline with hyperbolic stochastic coding.

Zhang, J., et al.
2021,  
Human molecular genetics

Exome sequencing revealed PDE11A as a novel candidate gene for early-onset Alzheimer's disease.

Qin, W., et al.
2021,  
JMIR mental health

Learning From Clinical Consensus Diagnosis in India to Facilitate Automatic Classification of Dementia: Machine Learning Study.

Jin, H., et al.
2021,  
Neurobiology of aging

Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population.

Marca-Ysabel, MV., et al.
2021,  
Neurobiology of aging

Genetic variants in glutamate-, Aβ-, and tau-related pathways determine polygenic risk for Alzheimer's disease.

Lawingco, T., et al.
2021,  
The journals of gerontology. Series A, Biological sciences and medical sciences

A Non-APOE Polygenic Risk Score for Alzheimer's Disease Is Associated With Cerebrospinal Fluid Neurofilament Light in a Representative Sample of Cognitively Unimpaired 70-Year Olds.

Skoog, I., et al.
2021,  
EMBO reports

Increased Alu RNA processing in Alzheimer brains is linked to gene expression changes.

Cheng, Y., et al.
2021,  
Journal of psychiatric research

Evaluation relationships between subjective wellbeing, personality traits, and Alzheimer's disease: A two-sample Mendelian randomization study.

Ma, Y., et al.
2021,  
Genome medicine

Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer's disease.

Gockley, J., et al.
2021,  
Acta neuropathologica communications

Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease.

Reddy, JS., et al.
2021,  
Communications biology

NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell data.

He, L., et al.
2021,  
Genes

A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.

Vattathil, SM., et al.
2021,  
Brain, behavior, & immunity - health

Differentially expressed genes in Alzheimer's disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1.

Li, QS.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease.

Kim, YW., et al.
2021,  
Medicinal research reviews

Artificial intelligence and machine learning-aided drug discovery in central nervous system diseases: State-of-the-arts and future directions.

Vatansever, S., et al.
2021,  
Nature aging

Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia risk.

Walker, KA., et al.
2021,  
Nature communications

Identification of putative causal loci in whole-genome sequencing data via knockoff statistics.

He, Z., et al.
2021,  
Neurology. Genetics

African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants.

Schindler, SE., et al.
2021,  
Proceedings. IEEE International Symposium on Biomedical Imaging

REGION SPECIFIC AUTOMATIC QUALITY ASSURANCE FOR MRI-DERIVED CORTICAL SEGMENTATIONS.

Gadewar, S., et al.
2021,  
Circulation. Genomic and precision medicine

Shared Genetic and Environmental Architecture of Cardiac Phenotypes Assessed via Echocardiography: The Framingham Heart Study.

Lin, H., et al.
2021,  
BMC bioinformatics

Modeling transcriptional regulation using gene regulatory networks based on multi-omics data sources.

Patel, N.
2021,  
Molecular psychiatry

Apolipoprotein E4 and meningeal lymphatics in Alzheimer disease: a conceptual framework.

Mentis, AA., et al.
2021,  
PLoS genetics

Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia.

Tang, S., et al.
2021,  
Proceedings of the National Academy of Sciences of the United States of America

Mendelian randomization identifies blood metabolites previously linked to midlife cognition as causal candidates in Alzheimer's disease.

Lord, J., et al.
2021,  
Translational psychiatry

Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue.

Patel, D., et al.
2021,  
Acta neuropathologica

Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer's disease in the European American population.

Kirola, L., et al.
2021,  
Scientific reports

Reconcile the debate over protective effects of BCG vaccine against COVID-19.

Fu, W., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols.

Lu, H., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols.

Wilcock, D., et al.
2021,  
Journal of neuropathology and experimental neurology

Asymmetry of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer Disease.

Walker, JM., et al.
2021,  
Aging

Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer's disease etiopathogenesis.

Madrid, L., et al.
2021,  
Proceedings of the National Academy of Sciences of the United States of America

TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau.

Ash, PEA., et al.
2021,  
Neuropsychology

Socioeconomic and psychosocial mechanisms underlying racial/ethnic disparities in cognition among older adults.

Zahodne, LB., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Long genes are more frequently affected by somatic mutations and show reduced expression in Alzheimer's disease: Implications for disease etiology.

Soheili-Nezhad, S., et al.
2021,  
American journal of human genetics

Genetic control of the human brain proteome.

Robins, C., et al.
2021,  
Scientific reports

Defining early changes in Alzheimer's disease from RNA sequencing of brain regions differentially affected by pathology.

Guennewig, B., et al.
2021,  
PLoS genetics

MOSTWAS: Multi-Omic Strategies for Transcriptome-Wide Association Studies.

Bhattacharya, A., et al.
2021,  
Genome biology

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders.

Nabais, MF., et al.
2021,  
Genes

Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants.

Patel, D., et al.
2021,  
Genes

The Impact of Complement Genes on the Risk of Late-Onset Alzheimer's Disease.

Carpanini, SM., et al.
2021,  
Neurobiology of aging

Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-ε4 carriers.

Fulton-Howard, B., et al.
2021,  
Nature communications

Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.

Novikova, G., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL).

Granot-Hershkovitz, E., et al.
2021,  
Cerebral cortex (New York, N.Y. : 1991)

Atlas55+: Brain Functional Atlas of Resting-State Networks for Late Adulthood.

Doucet, GE., et al.
2021,  
International journal of environmental research and public health

The GGLEAM Study: Understanding Glaucoma in the Ohio Amish.

Waksmunski, AR., et al.
2021,  
Genetic epidemiology

Set-based genetic association and interaction tests for survival outcomes based on weighted V statistics.

Li, C., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Non-coding variants in MYH11, FZD3, and SORCS3 are associated with dementia in women.

Blue, EE., et al.
2021,  
Alzheimer's research & therapy

Genetically determined blood pressure, antihypertensive medications, and risk of Alzheimer's disease: a Mendelian randomization study.

Ou, Y., et al.
2021,  
Cytometry. Part A : the journal of the International Society for Analytical Cytology

Tailor: Targeting heavy tails in flow cytometry data with fast, interpretable mixture modeling.

Ionita, M., et al.
2021,  
Translational psychiatry

Long runs of homozygosity are associated with Alzheimer's disease.

Moreno-Grau, S., et al.
2021,  
Translational psychiatry

Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease.

He, L., et al.
2021,  
Science advances

Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity.

Wahane, S., et al.
2021,  
Neurology

Association of Circulating Metabolites in Plasma or Serum and Risk of Stroke: Meta-analysis From 7 Prospective Cohorts.

Vojinovic, D., et al.
2021,  
Frontiers in radiology

Integrating Transcriptomics, Genomics, and Imaging in Alzheimer's Disease: A Federated Model.

Wu, J., et al.
2021,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention

Disentangled and Proportional Representation Learning for Multi-View Brain Connectomes.

Zhang, Y., et al.
2021,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention

Style Transfer Using Generative Adversarial Networks for Multi-Site MRI Harmonization.

Liu, M., et al.
2021,  
Journal of Alzheimer's disease : JAD

Potential Novel Genes for Late-Onset Alzheimer's Disease in East-Asian Descent Identified by APOE-Stratified Genome-Wide Association Study.

Kang, S., et al.
2021,  
Current Alzheimer research

Association of Dietary Prebiotic Consumption with Reduced Risk of Alzheimer's Disease in a Multiethnic Population.

Nishikawa, M., et al.
2021,  
Neuroepidemiology

The Association of Cognitive and Visual Function in a Nationally Representative Study of Older Adults in India.

Ehrlich, JR., et al.
2021,  
Heart & lung : the journal of critical care

Testing influences of APOE and BDNF genes and heart failure on cognitive function.

Jung, M., et al.
2021,  
NeuroImage. Clinical

A prospective cohort study of prodromal Alzheimer's disease: Prospective Imaging Study of Ageing: Genes, Brain and Behaviour (PISA).

Lupton, MK., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)

Polygenic risk scores for Alzheimer's disease are related to dementia risk in APOE ɛ4 negatives.

Najar, J., et al.
2021,  
Journal of Alzheimer's disease : JAD

Five-Year Change in Body Mass Index Predicts Conversion to Mild Cognitive Impairment or Dementia Only in APOE ɛ4 Allele Carriers.

Kadey, KR., et al.
2021,  
Brain communications

Defining functional variants associated with Alzheimer's disease in the induced immune response.

Harwood, JC., et al.
2021,  
Journal of neurogenetics

Analysis of whole genome sequenced cases and controls shows that the association of variants in TOMM40, BCAM, NECTIN2 and APOC1 with late onset Alzheimer's disease is driven by linkage disequilibrium with APOE ε2/ε3/ε4 alleles.

Curtis, D.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)

Transfer learning-trained convolutional neural networks identify novel MRI biomarkers of Alzheimer's disease progression.

Li, Y., et al.
2021,  
Frontiers in aging neuroscience

Similar Genetic Architecture of Alzheimer's Disease and Differential APOE Effect Between Sexes.

Wang, H., et al.
2021,  
Journal of Alzheimer's disease : JAD

Longitudinal Body Weight Change, Visit-To-Visit Body Weight Fluctuation, and Cognitive Decline Among Older Adults.

Lan, Y., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)

Causal association of cognitive reserve on Alzheimer's disease with putative sex difference.

Wang, H., et al.
2021,  
Methods in molecular biology (Clifton, N.J.)

Using INFERNO to Infer the Molecular Mechanisms Underlying Noncoding Genetic Associations.

Amlie-Wolf, A., et al.
2021,  
Alzheimer's & dementia (New York, N. Y.)

Association of neurogranin gene expression with Alzheimer's disease pathology in the perirhinal cortex.

Sun, X., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)

Polygenic score modifies risk for Alzheimer's disease in APOE ε4 homozygotes at phenotypic extremes.

Huq, AJ., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)

Cognitive screening with functional assessment improves diagnostic accuracy and attenuates bias.

González, DA., et al.
2021,  
Journal of Alzheimer's disease : JAD

Herpes Labialis, Chlamydophila pneumoniae, Helicobacter pylori, and Cytomegalovirus Infections and Risk of Dementia: The Framingham Heart Study.

Zilli, EM., et al.
2021,  
Frontiers in genetics

Copy Number Variation Identification on 3,800 Alzheimer's Disease Whole Genome Sequencing Data from the Alzheimer's Disease Sequencing Project.

Lee, W., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)

Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease.

Xue, D., et al.
2021,  
Schizophrenia bulletin

A White Matter Connection of Schizophrenia and Alzheimer's Disease.

Kochunov, P., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

The Brain Chart of Aging: Machine-learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans.

Habes, M., et al.
2021,  
Journal of the American Geriatrics Society

A Systematic Review of Delirium Biomarkers and Their Alignment with the NIA-AA Research Framework.

Wang, S., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Education differentially contributes to cognitive reserve across racial/ethnic groups.

Avila, JF., et al.
2021,  
Journal of the International Neuropsychological Society : JINS

Positive Psychosocial Factors and Cognitive Decline in Ethnically Diverse Older Adults.

Zahodne, LB., et al.
2021,  
Neurobiology of disease

Alzheimer's-associated PU.1 expression levels regulate microglial inflammatory response.

Pimenova, AA., et al.
2021,  
American journal of epidemiology

A Likelihood Ratio Test for Gene-Environment Interaction Based on the Trend Effect of Genotype Under an Additive Risk Model Using the Gene-Environment Independence Assumption.

de Rochemonteix, M., et al.
2021,  
Pharmacoepidemiology and drug safety

Patterns of anticonvulsant use and adverse drug events in older adults.

Moura, LMVR., et al.
2021,  
Alzheimer's research & therapy

Association between polygenic risk score of Alzheimer's disease and plasma phosphorylated tau in individuals from the Alzheimer's Disease Neuroimaging Initiative.

Zettergren, A., et al.
2021,  
BMC medicine

rs1990622 variant associates with Alzheimer's disease and regulates TMEM106B expression in human brain tissues.

Hu, Y., et al.
2021,  
Human genomics

Convergent lines of evidence support BIN1 as a risk gene of Alzheimer's disease.

Zhu, J., et al.
2021,  
Annals of neurology

Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome.

Andrews, SJ., et al.
2021,  
Neuron

Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.

Wang, M., et al.
2021,  
Genome biology

The variant call format provides efficient and robust storage of GWAS summary statistics.

Lyon, MS., et al.
2021,  
Science advances

Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets.

Neff, RA., et al.
2021,  
JAMA neurology

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.

Kunkle, BW., et al.
2021,  
Current neurology and neuroscience reports

Early-Onset Alzheimer's Disease: What Is Missing in Research?

Ayodele, T., et al.
2021,  
BMC microbiology

Comparison of rectal swab, glove tip, and participant-collected stool techniques for gut microbiome sampling.

Short, MI., et al.
2021,  
JAMA

Incidence of Transient Ischemic Attack and Association With Long-term Risk of Stroke.

Lioutas, V., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)

The Health & Aging Brain among Latino Elders (HABLE) study methods and participant characteristics.

O'Bryant, SE., et al.
2021,  
Dementia and geriatric cognitive disorders

Using Fractional Anisotropy Imaging to Detect Mild Cognitive Impairment and Alzheimer's Disease among Mexican Americans and Non-Hispanic Whites: A HABLE Study.

Hall, JR., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)

MRI biomarkers of small vessel disease and cognition: A cross-sectional study of a cognitively normal Mexican American cohort.

Vintimilla, R., et al.
2021,  
IEEE/ACM transactions on computational biology and bioinformatics

Multi-Task Sparse Canonical Correlation Analysis with Application to Multi-Modal Brain Imaging Genetics.

Du, L., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)

Pattern and degree of individual brain atrophy predicts dementia onset in dominantly inherited Alzheimer's disease.

Keret, O., et al.
2021,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention

Harmonization with Flow-Based Causal Inference.

Wang, R., et al.