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2022

2022,  
NPJ digital medicine

Factors associated with long-term use of digital devices in the electronic Framingham Heart Study

Pathiravasan, CH., et al.
2022,  
Alzheimer's Research & Therapy

Synergistic interaction of high blood pressure and cerebral beta-amyloid on tau pathology

Kim, T., et al.
2022,  
Journal of Medical Internet Research

Association Between Acoustic Features and Neuropsychological Test Performance in the Framingham Heart Study: Observational Study

Ding, H., et al.
2022,  
Translational Psychiatry

The impact of increasing levels of blood C-reactive protein on the inflammatory loci SPI1 and CD33 in Alzheimer's disease

Huang, J., et al.
2022,  
Brain: A Journal of Neurology

Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan

Luo, J., et al.
2022,  
Genome Medicine

Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes

Yang, C., et al.
2022,  
International Journal of Molecular Sciences

Physiological Consequences of Targeting 14-3-3 and Its Interacting Partners in Neurodegenerative Diseases

Ganne, A., et al.
2022,  
Cells

Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females

Pan, AL., et al.
2022,  
Biomedicines

Microglia and Cholesterol Handling: Implications for Alzheimer's Disease

Muñoz Herrera, OM.
2022,  
JAMA network open

Development and Validation of a Prediction Model for Need for Massive Transfusion During Surgery Using Intraoperative Hemodynamic Monitoring Data

Lee, SM., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Progranulin mutations in clinical and neuropathological Alzheimer's disease

Vardarajan, BN., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population

Godrich, D., et al.
2022,  
Nature

Medin co-aggregates with vascular amyloid-β in Alzheimer's disease

Wagner, J., et al.
2022,  
European journal of human genetics: EJHG

Exploiting family history in aggregation unit-based genetic association tests

Wang, Y., et al.
2022,  
Molecular & cellular proteomics: MCP

Glycoproteomics Landscape of Asymptomatic and Symptomatic Human Alzheimer's Disease Brain

Suttapitugsakul, S., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [11 C]UCB-J

Mecca, AP., et al.
2022,  
Aging Cell

SIRT3 deficiency decreases oxidative metabolism capacity but increases lifespan in male mice under caloric restriction

Dhillon, RS., et al.
2022,  
Population Health Management

Strengthening the Public Health Partnership and Telehealth Infrastructure to Reduce Health Care Disparities

Chen, J., et al.
2022,  
Genetic Epidemiology

Statistical power of transcriptome-wide association studies

He, R., et al.
2022,  
Journal of Computational Biology: A Journal of Computational Molecular Cell Biology

Multimodal Genotype and Phenotype Data Integration to Improve Partial Data-Based Longitudinal Prediction

Ganjdanesh, A., et al.
2022,  
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine

Consistency of Graph Theoretical Measurements of Alzheimer's Disease Fiber Density Connectomes Across Multiple Parcellation Scales

Xu, F., et al.
2022,  
Genetic Epidemiology

Genetic heterogeneity: Challenges, impacts, and methods through an associative lens

Woodward, AA., et al.
2022,  
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine

Preference Matrix Guided Sparse Canonical Correlation Analysis for Genetic Study of Quantitative Traits in Alzheimer's Disease

Sha, J., et al.
2022,  
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine

Mediation Analysis and Mixed-Effects Models for the Identification of Stage-specific Imaging Genetics Patterns in Alzheimer's Disease

Pala, D., et al.
2022,  
Nature Genetics

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease

Holstege, H., et al.
2022,  
Biomolecules

Heparan Sulfate Proteoglycans in Tauopathy

Zhu, Y., et al.
2022,  
Cell Reports

Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease

Xu, J., et al.
2022,  
Science Advances

Generative and reproducible benchmarks for comprehensive evaluation of machine learning classifiers

Orzechowski, P.
2022,  
Scientific Reports

The association between eicosanoids and incident atrial fibrillation in the Framingham Heart Study

Kornej, J., et al.
2022,  
Journal of Neuroinflammation

Neuroimmune proteins can differentiate between tauopathies

Cherry, JD., et al.
2022,  
Briefings in Bioinformatics

Integrating multi-omics summary data using a Mendelian randomization framework

Jin, C., et al.
2022,  
Genome Medicine

Towards elucidating disease-relevant states of neurons and glia by CRISPR-based functional genomics

Leng, K.
2022,  
Cells

Intranasal Peptide Therapeutics: A Promising Avenue for Overcoming the Challenges of Traditional CNS Drug Development

Bose, M., et al.
2022,  
JAMA

Development of a Prediction Model for Ascending Aortic Diameter Among Asymptomatic Individuals

Pirruccello, JP., et al.
2022,  
IEEE transactions on neural networks and learning systems

Contrastive Brain Network Learning via Hierarchical Signed Graph Pooling Model

Tang, H., et al.
2022,  
Cerebral Cortex (New York, N.Y.: 1991)

Co-expression network analysis of frontal cortex during the progression of Alzheimer's disease

Beck, JS., et al.
2022,  
Cell Reports

Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function

Pratt, KJB., et al.
2022,  
NPJ digital medicine

Multimodal machine learning in precision health: A scoping review

Kline, A., et al.
2022,  
Toxins

Omics Methods in Toxins Research-A Toolkit to Drive the Future of Scientific Inquiry

Romano, JD.
2022,  
Neuron

Microglial efferocytosis: Diving into the Alzheimer's disease gene pool

Romero-Molina, C., et al.
2022,  
Nature

APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes

Blanchard, JW., et al.
2022,  
Journal of Geriatric Psychiatry and Neurology

Towards Defining the Neuroanatomical Basis of Late-Onset Psychiatric Symptoms

Barker, MS., et al.
2022,  
Acta Neuropathologica

Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers

Jansen, IE., et al.
2022,  
Nature

Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid

Drieu, A., et al.
2022,  
Medical Care

Identifying Medicare Beneficiaries With Delirium

Moura, LMVR., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease

Jun, GR., et al.
2022,  
Neurobiology of Disease

Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities

Katsumata, Y., et al.
2022,  
Journal of Psychiatric Research

Association of autoimmune diseases with Alzheimer's disease: A mendelian randomization study

Yeung, CHC., et al.
2022,  
Molecular Psychiatry

Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning

Lahti, J., et al.
2022,  
Molecular & cellular proteomics: MCP

Regio-Specific N-Glycome and N-Glycoproteome Map of the Elderly Human Brain With and Without Alzheimer's Disease

Tena, J., et al.
2022,  
Autophagy

Autolysosomal acidification failure as a primary driver of Alzheimer disease pathogenesis

Lee, J.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Crosswalk between the Mini-Mental State Examination and the Telephone Interview for Cognitive Status (TICS-27/30/40)

Hlávka, JP., et al.
2022,  
Proceedings of the National Academy of Sciences of the United States of America

Understanding the roles of central and autonomic activity during sleep in the improvement of working memory and episodic memory

Chen, P., et al.
2022,  
The American Journal of Geriatric Psychiatry: Official Journal of the American Association for Geriatric Psychiatry

An HIT-Supported Care Coordination Framework for Reducing Structural Racism and Discrimination for Patients With ADRD

Chen, J., et al.
2022,  
EClinicalMedicine

Different loneliness types, cognitive function, and brain structure in midlife: Findings from the Framingham Heart Study

Tao, Q., et al.
2022,  
Acta Neuropathologica Communications

Artificial intelligence-derived neurofibrillary tangle burden is associated with antemortem cognitive impairment

Marx, GA., et al.
2022,  
Translational Neurodegeneration

Myelin repair in Alzheimer's disease: a review of biological pathways and potential therapeutics

Hirschfeld, LR., et al.
2022,  
Molecular Neurodegeneration

The Golgi apparatus: Site for convergence of COVID-19 brain fog and Alzheimer's disease?

Wang, Y.
2022,  
Nature Communications

Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model

Rickner, HD., et al.
2022,  
Human Molecular Genetics

Human Molecular Genetics Review Issue 2022

Cheng, F.
2022,  
Human Molecular Genetics

Quantitative trait locus (xQTL) approaches identify risk genes and drug targets from human non-coding genomes

Bykova, M., et al.
2022,  
Biochemistry

Ganglioside-Enriched Phospholipid Vesicles Induce Cooperative Aβ Oligomerization and Membrane Disruption

Saha, J., et al.
2022,  
Cell Reports. Medicine

Transcriptomics-based network medicine approach identifies metformin as a repurposable drug for atrial fibrillation

Lal, JC., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains

Novotny, BC., et al.
2022,  
Nature Communications

Spatial snapshots of amyloid precursor protein intramembrane processing via early endosome proteomics

Park, H., et al.
2022,  
Nature Communications

Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis

Boland, S., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Whole genome sequencing-based copy number variations reveal novel pathways and targets in Alzheimer's disease

Ming, C., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

The National Institute on Aging Late-Onset Alzheimer's Disease Family Based Study: A resource for genetic discovery

Reyes-Dumeyer, D., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Identifying differential regulatory control of APOE ɛ4 on African versus European haplotypes as potential therapeutic targets

Nuytemans, K., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance

Gao, Y., et al.
2022,  
Movement Disorders: Official Journal of the Movement Disorder Society

Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy

Hopfner, F., et al.
2022,  
Molecular Psychiatry

Cognitive performance protects against Alzheimer's disease independently of educational attainment and intelligence

Hu, Y., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk

Hu, Y., et al.
2022,  
Nature Biotechnology

DIALOGUE maps multicellular programs in tissue from single-cell or spatial transcriptomics data

Jerby-Arnon, L.
2022,  
Neurobiology of Aging

RNASE6 is a novel modifier of APOE-ε4 effects on cognition

Seto, M., et al.
2022,  
Preventive Medicine

Rural and urban disparities in potentially preventable hospitalizations among US patients with Alzheimer's Disease and Related Dementias: Evidence of hospital-based telehealth and enabling services

Wang, N., et al.
2022,  
Acta Neuropathologica

Rainwater Charitable Foundation criteria for the neuropathologic diagnosis of progressive supranuclear palsy

Roemer, SF., et al.
2022,  
Journal of Palliative Medicine

Symptom Control Research

Periyakoil, VS., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Moving beyond disclosure: Stages of care in preclinical Alzheimer's disease biomarker testing

Ketchum, FB., et al.
2022,  
Current Opinion in Physiology

Mechanisms Controlling Selective Elimination of Damaged Lysosomes

Hoyer, MJ., et al.
2022,  
Epilepsy Research

A replicable, open-source, data integration method to support national practice-based research & quality improvement systems

Fernandes, M., et al.
2022,  
PLoS computational biology

Deep mendelian randomization: Investigating the causal knowledge of genomic deep learning models

Malina, S., et al.
2022,  
Human Genetics

Genome interpretation using in silico predictors of variant impact

Katsonis, P., et al.
2022,  
Computer Science & Information Technology

Tensor-Based Multi-Modality Feature Selection and Regression for Alzheimer's Disease Diagnosis

Yu, J., et al.
2022,  
Genome Research

Mosaic loss of Chromosome Y in aged human microglia

Vermeulen, MC., et al.
2022,  
Psychiatry and Clinical Neurosciences

Spouse bereavement and brain pathologies: A propensity score matching study

Kim, JW., et al.
2022,  
Neurology. Genetics

A Fast and Robust Strategy to Remove Variant-Level Artifacts in Alzheimer Disease Sequencing Project Data

Belloy, ME., et al.
2022,  
Nature

Stroke genetics informs drug discovery and risk prediction across ancestries

Mishra, A., et al.
2022,  
BMC bioinformatics

Deep multiview learning to identify imaging-driven subtypes in mild cognitive impairment

Feng, Y., et al.
2022,  
Human Molecular Genetics

Genotype-phenotype correlation of T-cell subtypes reveals senescent and cytotoxic genes in Alzheimer's disease

Dressman, D., et al.
2022,  
BMC bioinformatics

Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data

Mai, H., et al.
2022,  
Scientific Reports

Molecular pathways enhance drug response prediction using transfer learning from cell lines to tumors and patient-derived xenografts

Tang, Y., et al.
2022,  
Neurogenetics

Whole-exome sequencing reveals PSEN1 and ATP7B combined variants as a possible cause of early-onset Lewy body dementia: a case study of genotype-phenotype correlation

Tábuas-Pereira, M., et al.
2022,  
Alzheimer's Research & Therapy

Distinct sex-specific DNA methylation differences in Alzheimer's disease

C Silva, T., et al.
2022,  
Human Genetics

The promise of automated machine learning for the genetic analysis of complex traits

Manduchi, E., et al.
2022,  
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences

Association Between Mediterranean Diet and Functional Status in Older Adults: A Longitudinal Study Based on the Washington Heights-Inwood Columbia Aging Project

Guo, J., et al.
2022,  
Trends in genetics: TIG

'Fly-ing' from rare to common neurodegenerative disease mechanisms

Ma, M., et al.
2022,  
Neurobiology of Aging

Amyloid, cerebrovascular disease, and neurodegeneration biomarkers are associated with cognitive trajectories in a racially and ethnically diverse, community-based sample

Lao, PJ., et al.
2022,  
Human Molecular Genetics

Genetic architecture of RNA editing regulation in Alzheimer's disease across diverse ancestral populations

Gardner, OK., et al.
2022,  
Genes

Mining High-Level Imaging Genetic Associations via Clustering AD Candidate Variants with Similar Brain Association Patterns

Wu, R., et al.
2022,  
Proceedings of the National Academy of Sciences of the United States of America

Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation

Saroja, SR., et al.
2022,  
Science (New York, N.Y.)

Functional regulatory variants implicate distinct transcriptional networks in dementia

Cooper, YA., et al.
2022,  
Bioinformatics (Oxford, England)

Omnibus and Robust Deconvolution Scheme for Bulk RNA Sequencing Data Integrating Multiple Single-Cell Reference Sets and Prior Biological Knowledge

Chen, C., et al.
2022,  
Nature Communications

Cross-tissue analysis of blood and brain epigenome-wide association studies in Alzheimer's disease

C Silva, T., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Differential diagnosis of amnestic dementia patients based on an FDG-PET signature of autopsy-confirmed LATE-NC

Grothe, MJ., et al.
2022,  
Human Molecular Genetics

Scalable approaches for functional analyses of whole-genome sequencing non-coding variants

Kuksa, PP., et al.
2022,  
Brain: A Journal of Neurology

Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI

Yang, Y., et al.
2022,  
Neuropsychology

Cognitive domain harmonization and cocalibration in studies of older adults

Mukherjee, S., et al.
2022,  
BMC medical genomics

Identifying genetic markers enriched by brain imaging endophenotypes in Alzheimer's disease

Kim, M., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau

Frank, B., et al.
2022,  
Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism

Genome-wide association study of brain arteriolosclerosis

Shade, LM., et al.
2022,  
Journal of Alzheimer's disease: JAD

The Advisory Group on Risk Evidence Education for Dementia: Multidisciplinary and Open to All

Rosen, AC., et al.
2022,  
Brain: A Journal of Neurology

Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease

Eissman, JM., et al.
2022,  
Translational Psychiatry

Polygenic resilience scores capture protective genetic effects for Alzheimer's disease

Hou, J., et al.
2022,  
Human Molecular Genetics

Accounting for nonlinear effects of gene expression identifies additional associated genes in transcriptome-wide association studies

Lin, Z., et al.
2022,  
Cells

A Method for Bridging Population-Specific Genotypes to Detect Gene Modules Associated with Alzheimer's Disease

Dai, Y., et al.
2022,  
HGG advances

The genetic architecture of Alzheimer disease risk in the Ohio and Indiana Amish

Osterman, MD., et al.
2022,  
Nucleic Acids Research

EPIMUTESTR: a nearest neighbor machine learning approach to predict cancer driver genes from the evolutionary action of coding variants

Parvandeh, S., et al.
2022,  
PLoS genetics

A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer's Disease in African Ancestry

Rajabli, F., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Contribution of Alzheimer's biomarkers and risk factors to cognitive impairment and decline across the Alzheimer's disease continuum

Tosun, D., et al.
2022,  
JAMA neurology

Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease

Le Guen, Y., et al.
2022,  
Acta Neuropathologica

FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer's disease

Lee, AJ., et al.
2022,  
Stem Cell Research

Generation of two iPSC lines (UMi038-A & UMi039-A) from siblings bearing an Alzheimer's disease-associated variant in SORL1

DeRosa, BA., et al.
2022,  
Annals of Neurology

Association of Apolipoprotein E ɛ4 Allele with Enlarged Perivascular Spaces

Pinheiro, A., et al.
2022,  
Brain: A Journal of Neurology

Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate

Mishra, A., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women

Chung, J., et al.
2022,  
Biological Psychiatry

Integrative Co-methylation Network Analysis Identifies Novel DNA Methylation Signatures and Their Target Genes in Alzheimer's Disease

Kim, JP., et al.
2022,  
Cell

Cholesterol and matrisome pathways dysregulated in astrocytes and microglia

Tcw, J., et al.
2022,  
American Journal of Human Genetics

Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss

Trpchevska, N., et al.
2022,  
BMC genomics

Integrative analysis of summary data from GWAS and eQTL studies implicates genes differentially expressed in Alzheimer's disease

Lee, B., et al.
2022,  
American Journal of Human Genetics

Integration of rare expression outlier-associated variants improves polygenic risk prediction

Smail, C., et al.
2022,  
Biological Psychiatry. Cognitive Neuroscience and Neuroimaging

Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes

Le Grand, Q., et al.
2022,  
Molecular Psychiatry

Admixture Mapping of Alzheimer's disease in Caribbean Hispanics identifies a new locus on 22q13.1

Kizil, C., et al.
2022,  
Nature Protocols

Chromatin accessibility profiling by ATAC-seq

Grandi, FC., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease

Horgusluoglu, E., et al.
2022,  
Aging Cell

Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells

You, Y., et al.
2022,  
Cells

Single Cell/Nucleus Transcriptomics Comparison in Zebrafish and Humans Reveals Common and Distinct Molecular Responses to Alzheimer's Disease

Cosacak, MI., et al.
2022,  
Neurology

Genetic Risk, Midlife Life's Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study

Tin, A., et al.
2022,  
Nucleic Acids Research

MethReg: estimating the regulatory potential of DNA methylation in gene transcription

Silva, TC., et al.
2022,  
Scientific Reports

Genome-wide association of polygenic risk extremes for Alzheimer's disease in the UK Biobank

Gouveia, C., et al.
2022,  
Journal of Neuroinflammation

High-fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner

Gannon, OJ., et al.
2022,  
Brain: A Journal of Neurology

Antemortem plasma phosphorylated tau (181) predicts Alzheimer's disease neuropathology and regional tau at autopsy

Morrison, MS., et al.
2022,  
JAMA psychiatry

Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression

Wen, J., et al.
2022,  
Genome Research

A general calculus of fitness landscapes finds genes under selection in cancers

Hsu, T., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Genetic variants in the SHISA6 gene are associated with delayed cognitive impairment in two family datasets

Ramos, J., et al.
2022,  
European Journal of Neurology

Rare variants in TP73 in a frontotemporal dementia cohort link this gene with primary progressive aphasia phenotypes

Tábuas-Pereira, M., et al.
2022,  
Current Protocols

Molecular Quantitative Trait Locus Mapping in Human Complex Diseases

Olayinka, OA., et al.
2022,  
Annals of Clinical and Translational Neurology

Correlation of plasma and neuroimaging biomarkers in Alzheimer's disease

Brickman, AM., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Current directions in tau research: Highlights from Tau 2020

Sexton, C., et al.
2022,  
Cells

Identifying Blood Biomarkers for Dementia Using Machine Learning Methods in the Framingham Heart Study

Lin, H., et al.
2022,  
Neurology

Multiple Cortical to Striatal Accumulation Trajectories of β-Amyloid: Do All Roads Lead to Rome?

Vogel, JW.
2022,  
Neuron

ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias

Martens, YA., et al.
2022,  
Journal of Medical Internet Research

Associations Between the Digital Clock Drawing Test and Brain Volume: Large Community-Based Prospective Cohort (Framingham Heart Study)

Yuan, J., et al.
2022,  
Scientific Reports

Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90

Heath, L., et al.
2022,  
Med (New York, N.Y.)

Integrating functional genomics with genetics to understand the biology of ALS and FTD

Cruchaga, C.
2022,  
Communications Biology

Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels

Sarnowski, C., et al.
2022,  
American Journal of Human Genetics

Family history aggregation unit-based tests to detect rare genetic variant associations with application to the Framingham Heart Study

Wang, Y., et al.
2022,  
Circulation

Circulating Metabolome and White Matter Hyperintensities in Women and Men

Sliz, E., et al.
2022,  
Neurobiology of Disease

Soluble TREM2: Innocent bystander or active player in neurological diseases?

Filipello, F., et al.
2022,  
Journal of the International Neuropsychological Society: JINS

Midlife Vascular Factors and Prevalence of Mild Cognitive Impairment in Late-Life in Mexico

Arce Rentería, M., et al.
2022,  
Nature Genetics

New insights into the genetic etiology of Alzheimer's disease and related dementias

Bellenguez, C., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Replication study of AD-associated rare variants

Neupane, A., et al.
2022,  
Genome Research

An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns

Jin, B., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Midlife lipid and glucose levels are associated with Alzheimer's disease

Zhang, X., et al.
2022,  
Briefings in Bioinformatics

Deep learning-based identification of genetic variants: application to Alzheimer's disease classification

Jo, T., et al.
2022,  
Acta Neuropathologica Communications

Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease

Chen, H., et al.
2022,  
NeuroImage

Deep learning for Alzheimer's disease: Mapping large-scale histological tau protein for neuroimaging biomarker validation

Ushizima, D., et al.
2022,  
NAR genomics and bioinformatics

FILER: a framework for harmonizing and querying large-scale functional genomics knowledge

Kuksa, PP., et al.
2022,  
Journal of magnetic resonance imaging: JMRI

Deep Generative Medical Image Harmonization for Improving Cross-Site Generalization in Deep Learning Predictors

Bashyam, VM., et al.
2022,  
Alzheimer's Research & Therapy

Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease

Panitch, R., et al.
2022,  
Social Science & Medicine (1982)

Longitudinal associations between racial discrimination and hippocampal and white matter hyperintensity volumes among older Black adults

Zahodne, LB., et al.
2022,  
Alzheimer's Research & Therapy

Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping

Belloy, ME., et al.
2022,  
Medical Image Analysis

Embracing the disharmony in medical imaging: A Simple and effective framework for domain adaptation

Wang, R., et al.
2022,  
Aging Cell

Aging-related cell type-specific pathophysiologic immune responses that exacerbate disease severity in aged COVID-19 patients

Hou, Y., et al.
2022,  
Current Opinion in Structural Biology

Interpretable artificial intelligence and exascale molecular dynamics simulations to reveal kinetics: Applications to Alzheimer's disease

Martin, W., et al.
2022,  
Neurology. Genetics

Confirming Pathogenicity of the F386L PSEN1 Variant in a South Asian Family With Early-Onset Alzheimer Disease

Eger, SJ., et al.
2022,  
Genetic Epidemiology

Precisely modeling zero-inflated count phenotype for rare variants

Fan, Q., et al.
2022,  
Neurobiology of Aging

Cognitive reserve proxies, Alzheimer pathologies, and cognition

Ko, K., et al.
2022,  
BMC genomics

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