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2025

2025,  
Sleep medicine

Exploring nightly variability and clinical influences on sleep measures: insights from a digital brain health platform.

Ding, H., et al.
2025,  
Alzheimer disease and associated disorders

Asian Cohort for Alzheimer Disease (ACAD) Pilot Study: Vietnamese Americans.

Peavy, GM., et al.
2025,  
Alzheimer disease and associated disorders

Visuospatial and Verbal Memory Differences in Amish Individuals With Alzheimer Disease and Related Dementias.

Prough, MB., et al.
2025,  
Alzheimer disease and associated disorders

Clinical Profiles of Arteriolosclerosis and Alzheimer Disease at Mild Cognitive Impairment and Mild Dementia in a National Neuropathology Cohort.

Yang, D.
2025,  
Alzheimer disease and associated disorders

A Novel Method for Establishing Functional Change in Older Adults With Cognitive Impairment.

González, DA., et al.
2025,  
Journal of the American Society of Nephrology : JASN

Uremic Toxins, CKD, and Cognitive Dysfunction.

Andrews, TD., et al.
2025,  
Nature human behaviour

Charting brain functional development from birth to 6 years of age.

Yin, W., et al.
2025,  
Annals of neurology

The Use of Antihypertensive Medication and In Vivo Alzheimer's Disease Pathology.

Keum, M., et al.
2025,  
Molecular psychiatry

X-chromosome-wide association study for Alzheimer's disease.

Le Borgne, J., et al.
2025,  
Glia

Contributions of Genetic Variation in Astrocytes to Cell and Molecular Mechanisms of Risk and Resilience to Late-Onset Alzheimer's Disease.

Lee, H., et al.
2025,  
The journals of gerontology. Series B, Psychological sciences and social sciences

Understanding the Stress Process Among Mexican American Adults Aged 50 and Older in the United States.

Muñoz, E., et al.
2025,  
Acta neuropathologica communications

Age-dependent interactions of APOE isoform 4 and Alzheimer's disease neuropathology: findings from the NACC.

Hayes, CA., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Sleep macro-architecture, nocturnal hypoxemia, and Alzheimer's disease-related MRI patterns among diverse older adults.

Liu, DX., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Racial ethnic variations in the cardiometabolic determinants and blood pressure of white matter hyperintensities among females-The HABS-HD Study.

Hayes, CA., et al.
2025,  
medRxiv : the preprint server for health sciences

Identification and Validation of New Molecular Subtypes within the Early and Late Mild Cognitive Impairment Stages of Alzheimer's Disease.

Li, B., et al.
2025,  
The Clinical neuropsychologist

Health insurance coverage moderates the relationship between metabolic syndrome and baseline memory outcomes in Latino older adults.

Breton, J., et al.
2025,  
medRxiv : the preprint server for health sciences

Mediating effect of pro-inflammatory cytokines in the association between depression, anxiety, and cardiometabolic disorders in an ethnically diverse community-dwelling middle-aged and older US population.

Hallab, A.
2025,  
medRxiv : the preprint server for health sciences

Mediating role of Interleukin-6 in the predictive association of diabetes with Hippocampus atrophy, Amyloid, Tau, and Neurofilament pathology at pre-clinical stages of diabetes-related cognitive impairment.

Hallab, A.
2025,  
Nature genetics

CHOIR improves significance-based detection of cell types and states from single-cell data.

Sant, C., et al.
2025,  
Neuron

Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures across the Alzheimer disease continuum.

Ali, M., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Ubiquitin-proteasome system in the different stages of dominantly inherited Alzheimer's disease.

Liu, H., et al.
2025,  
Molecular neurodegeneration

Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication.

Zhao, X., et al.
2025,  
Research square

Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American Populations.

Acosta-Uribe, J., et al.
2025,  
medRxiv : the preprint server for health sciences

Interpretable MRI-Based Deep Learning for Alzheimer's Risk and Progression.

Lu, B., et al.
2025,  
BioData mining

Network-based analyses of multiomics data in biomedicine.

Kumar, R., et al.
2025,  
medRxiv : the preprint server for health sciences

Bayesian inference of genetic pleiotropy identifies drug targets and repurposable medicines for human complex diseases.

Lorincz-Comi, N.
2025,  
Proceedings of the National Academy of Sciences of the United States of America

Inhibiting 15-PGDH blocks blood-brain barrier deterioration and protects mice from Alzheimer's disease and traumatic brain injury.

Koh, Y., et al.
2025,  
medRxiv : the preprint server for health sciences

D3MI: an efficient and powerful federated imputation method for bias reduction in the analysis of distributed incomplete data by accounting for within-site correlation and between-site heterogeneity.

Lian, Y., et al.
2025,  
International journal of molecular sciences

Genetic, Transcriptomic, and Epigenomic Insights into Sjögren's Disease: An Integrative Network Investigation and Immune Diseases Comparison.

Enduru, N., et al.
2025,  
Briefings in bioinformatics

iGTP: learning interpretable cellular embedding for inferring biological mechanisms underlying single-cell transcriptomics.

Hsieh, K., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference.

Frost, B., et al.
2025,  
Journal of neurology, neurosurgery, and psychiatry

Telomere length, in vivo Alzheimer's disease pathologies and cognitive decline in older adults.

Jung, JH., et al.
2025,  
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

The Effect of Cholinesterase Inhibitors on Neurodegeneration in Individuals with Amnestic Mild Cognitive Impairment.

Byeon, G., et al.
2025,  
Communications biology

Leveraging multivariate information for community detection in functional brain networks.

Puxeddu, MG., et al.
2025,  
Nature medicine

A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer's disease.

Oh, HS., et al.
2025,  
The journal of prevention of Alzheimer's disease

Association of dietary fatty acids with longitudinal change in plasma-based biomarkers of Alzheimer's disease.

Hoost, SS., et al.
2025,  
medRxiv : the preprint server for health sciences

Heritability of Alzheimer-related plasma biomarkers in the Amish population.

Wang, P., et al.
2025,  
Nature communications

An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration.

Leventhal, MJ., et al.
2025,  
Movement disorders : official journal of the Movement Disorder Society

Copy Number Variation and Haplotype Analysis of 17q21.31 Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells.

Wang, H., et al.
2025,  
medRxiv : the preprint server for health sciences

Multi-population Genome-Wide Association Study Identifies Multiple Novel Loci associated with Asymptomatic Intracranial Large Artery Stenosis.

Liu, M., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Alzheimer's Disease Sequencing Project release 4 whole genome sequencing dataset.

Leung, YY., et al.
2025,  
bioRxiv : the preprint server for biology

Sequencing the gaps: dark genomic regions persist in CHM13 despite long-read advances.

Wadsworth, ME., et al.
2025,  
Journal of Alzheimer's disease : JAD

Association of Alzheimer's disease biomarkers with low premorbid intellectual functioning in a multi-ethnic community-dwelling cohort: A cross-sectional study of HABS-HD.

Abdullah, L., et al.
2025,  
Proceedings. IEEE International Symposium on Biomedical Imaging

AUTOENCODER FOR 4-DIMENSIONAL FIBER ORIENTATION DISTRIBUTIONS FROM DIFFUSION MRI.

Huang, S., et al.
2025,  
medRxiv : the preprint server for health sciences

Chronic emotional stress and mediating role of Interleukine-6 in the association with cardiometabolic disorders in a multiethnic middle-aged and older US-population.

Hallab, A.
2025,  
medRxiv : the preprint server for health sciences

Mediating effect of pro-inflammatory cytokines in the association between depression, anxiety, and cardiometabolic disorders in an ethnically diverse middle-aged and older population.

Hallab, A.
2025,  
Cell

Turnover atlas of proteome and phosphoproteome across mouse tissues and brain regions.

Li, W., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Somatic and Stem Cell Bank to study the contribution of African ancestry to dementia: African iPSC Initiative.

Maina, MB., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Genome-wide association analysis identifies APOE as a mitophagy modifier in Lewy body disease.

Hou, X., et al.
2025,  
Genome research

Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease.

Jensen, TD., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Addressing overfitting bias due to sample overlap in polygenic risk scoring.

Jeong, S., et al.
2025,  
Human brain mapping

MRI Distance Measures as a Predictor of Subsequent Clinical Status During the Preclinical Phase of Alzheimer's Disease and Related Disorders.

Zhang, X., et al.
2025,  
PLoS genetics

Enhancing nonlinear transcriptome- and proteome-wide association studies via trait imputation with applications to Alzheimer's disease.

He, R., et al.
2025,  
Nature genetics

Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes.

Henry, A., et al.
2025,  
Scientific reports

Association of the digital clock drawing test with amyloid and tau PET biomarkers in low age risk adults.

Ding, H., et al.
2025,  
Nature communications

A genetically informed brain atlas for enhancing brain imaging genomics.

Bao, J., et al.
2025,  
BioData mining

Enhancing clinical outcome predictions through effective sample size evaluation in graph-based digital twin modeling.

Li, X., et al.
2025,  
ArXiv

Knowledge-Driven Feature Selection and Engineering for Genotype Data with Large Language Models.

Lee, J., et al.
2025,  
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Utilization of precision medicine digital twins for drug discovery in Alzheimer's disease.

Ren, Y., et al.
2025,  
Scientific reports

A pioneering artificial intelligence tool to predict treatment outcomes in ovarian cancer via diagnostic laparoscopy.

Ma, X., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

APOE and Alzheimer's disease and related dementias risk among 12,221 Hispanics/Latinos.

Barral, S., et al.
2025,  
medRxiv : the preprint server for health sciences

Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review.

Liu, S., et al.
2025,  
Alzheimer's research & therapy

Integrative network analysis reveals novel moderators of Aβ-Tau interaction in Alzheimer's disease.

Kitani, A.
2025,  
Acta neuropathologica

LATE-NC Stage 3: a diagnostic rubric to differentiate severe LATE-NC from FTLD-TDP.

Shahidehpour, RK., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Long sleep duration, cognitive performance, and the moderating role of depression: A cross-sectional analysis in the Framingham Heart Study.

Young, VM., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Elevated serum cortisol associated with early-detected increase of brain amyloid deposition in Alzheimer's disease imaging biomarkers among menopausal women: The Framingham Heart Study.

Salardini, A., et al.
2025,  
Neurology. Genetics

Whole Genome Variable Number Tandem Repeat Analysis in Alzheimer Disease.

Heath, A., et al.
2025,  
Nature genetics

Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing.

Humphrey, J., et al.
2025,  
medRxiv : the preprint server for health sciences

SingleBrain: A Meta-Analysis of Single-Nucleus eQTLs Linking Genetic Risk to Brain Disorders.

Jang, B., et al.
2025,  
bioRxiv : the preprint server for biology

Cytosine-to-uracil RNA editing is upregulated by pro-inflammatory stimulation of myeloid cells.

Seo, H., et al.
2025,  
Journal of the American Geriatrics Society

Design and methodology of the harmonized diagnostic assessment of dementia for the longitudinal aging study in India: Wave 2.

Khobragade, PY., et al.
2025,  
Neuropsychology

The association of multilingualism with diverse language families and cognition among adults with and without education in India.

Petrosyan, S., et al.
2025,  
Nature biotechnology

Analysis and benchmarking of small and large genomic variants across tandem repeats.

English, AC., et al.
2025,  
Nature genetics

Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk.

Choi, SH., et al.
2025,  
Journal of neurology, neurosurgery, and psychiatry

Genetics impact risk of Alzheimer's disease through mechanisms modulating structural brain morphology in late life.

Korologou-Linden, R., et al.
2025,  
International journal of molecular sciences

Differential Transcriptional Programs Reveal Modular Network Rearrangements Associated with Late-Onset Alzheimer's Disease.

Pérez-González, AP., et al.
2025,  
medRxiv : the preprint server for health sciences

Leveraging multimodal neuroimaging and GWAS for identifying modality-level causal pathways to Alzheimer's disease.

Tian, Y., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Distinct medical and substance use histories associate with cognitive decline in Alzheimer's disease.

Mansel, C., et al.
2025,  
Research square

Sex-specific Associations of Gene Expression with Alzheimer's Disease Neuropathology and Ante-mortem Cognitive Performance.

Dumitrescu, L., et al.
2025,  
PLoS genetics

Local genetic covariance analysis with lipid traits identifies novel loci for early-onset Alzheimer's Disease.

Ray, NR., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Generalizability of tau and amyloid plasma biomarkers in Alzheimer's disease cohorts of diverse genetic ancestries.

Griswold, AJ., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Chronic stress, social support, and Alzheimer's blood-based biomarkers in the HABS-HD study.

Lee, JK., et al.
2025,  
medRxiv : the preprint server for health sciences

Objective Sleep Quality in Diverse Older Adults: the Importance of Race and Ethnicity and Sex.

Cavaillès, C., et al.
2025,  
Neurobiology of disease

Alzheimer's disease risk ABCA7 p.A696S variant disturbs the microglial response to amyloid pathology in mice.

Ma, X., et al.
2025,  
bioRxiv : the preprint server for biology

Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer's disease.

Trushin, S., et al.
2025,  
Neuron

The night's watch: Exploring how sleep protects against neurodegeneration.

Parhizkar, S.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Neuronal ABCA7 deficiency aggravates mitochondrial dysfunction and neurodegeneration in Alzheimer's disease.

Wang, N., et al.
2025,  
bioRxiv : the preprint server for biology

Midkine Attenuates Aβ Fibril Assembly and Amyloid Plaque Formation.

Zaman, M., et al.
2025,  
Neuron

CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions.

Li, E., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Interactions between menopause and high-fat diet on cognition and pathology in a mouse model of Alzheimer's disease.

Abi-Ghanem, C., et al.
2025,  
NPJ Parkinson's disease

Longitudinal multi-omics in alpha-synuclein Drosophila model discriminates disease- from age-associated pathologies in Parkinson's disease.

Moore, J., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

The impact of arteriolosclerosis on cognitive impairment in decedents without severe dementia from the National Alzheimer's Coordinating Center.

Hayes, CA., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Amyloid PET predicts longitudinal functional and cognitive trajectories in a heterogeneous cohort.

Younes, K., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Plasma protein risk scores for mild cognitive impairment and Alzheimer's disease in the Framingham heart study.

Rehman, H., et al.
2025,  
Neural networks : the official journal of the International Neural Network Society

BPEN: Brain Posterior Evidential Network for trustworthy brain imaging analysis.

Ye, K., et al.
2025,  
BioData mining

High-dimensional mediation analysis reveals the mediating role of physical activity patterns in genetic pathways leading to AD-like brain atrophy.

Xu, H., et al.
2025,  
Communications biology

Longitudinal excitation-inhibition balance altered by sex and APOE-ε4.

Burns, AP., et al.
2025,  
medRxiv : the preprint server for health sciences

Leveraging functional annotations to map rare variants associated with Alzheimer's disease with gruyere.

Das, A., et al.
2025,  
medRxiv : the preprint server for health sciences

Vision Transformer Autoencoders for Unsupervised Representation Learning: Capturing Local and Non-Local Features in Brain Imaging to Reveal Genetic Associations.

Islam, SR., et al.
2025,  
Human genetics

Assessing the predicted impact of single amino acid substitutions in calmodulin for CAGI6 challenges.

Turina, P., et al.
2025,  
Human genetics

Assessing the predicted impact of single amino acid substitutions in MAPK proteins for CAGI6 challenges.

Turina, P., et al.
2025,  
Human genetics

Evaluation of enzyme activity predictions for variants of unknown significance in Arylsulfatase A.

Jain, S., et al.
2025,  
The Journal of clinical endocrinology and metabolism

Defining Continuous Glucose Monitor Time in Range in a Large, Community-Based Cohort Without Diabetes.

Spartano, NL., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Dynamic lifetime risk prediction of Alzheimer's disease with longitudinal cognitive assessment measurements.

Ding, H., et al.
2025,  
JMIR formative research

Digital Assessment of Cognitive Health in Outpatient Primary Care: Usability Study.

Doerr, AJ., et al.
2025,  
Bioinformatics (Oxford, England)

Rethinking GWAS: how lessons from genetic screens and artificial intelligence could reveal biological mechanisms.

Hazelett, DJ.
2025,  
Bioinformatics (Oxford, England)

Predicting explainable dementia types with LLM-aided feature engineering.

Kashyap, AM., et al.
2025,  
PLoS medicine

Efficacy and safety of passive immunotherapies targeting amyloid beta in Alzheimer's disease: A systematic review and meta-analysis.

Tonegawa-Kuji, R., et al.
2025,  
Genome medicine

Structural variants linked to Alzheimer's disease and other common age-related clinical and neuropathologic traits.

Vialle, RA., et al.
2025,  
Stroke

Socioeconomic Status and Stroke: A Review of the Latest Evidence on Inequalities and Their Drivers.

Pantoja-Ruiz, C., et al.
2025,  
medRxiv : the preprint server for health sciences

Genetic Regulation of the Metabolome Differs by Sex, Alzheimer's Disease Stage, and Plasma Biomarker Status.

Eissman, JM., et al.
2025,  
eNeuro

Detection of Mitotic Neuroblasts Provides Additional Evidence of Steady-State Neurogenesis in the Adult Small Intestinal Myenteric Plexus.

Gorecki, AM., et al.
2025,  
Journal of neurotrauma

Traumatic Brain Injury and Alzheimer's Disease Biomarkers: A Systematic Review of Findings from Amyloid and Tau Positron Emission Tomography.

Dybing, KM., et al.
2025,  
Journal of Alzheimer's disease : JAD

Daily fluid intake and brain amyloid deposition: A cohort study.

Kim, JW., et al.
2025,  
Research square

Large-scale Plasma Proteomic Profiling Unveils Novel Diagnostic Biomarkers and Pathways for Alzheimer's Disease.

Cruchaga, C., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Considerations in the clinical use of amyloid PET and CSF biomarkers for Alzheimer's disease.

Leuzy, A., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Preclinical Alzheimer's disease shows alterations in circulating neuronal-derived extracellular vesicle microRNAs in a multiethnic cohort.

Reho, P., et al.
2025,  
Journal of the American Geriatrics Society

Neighborhoods, Networks, and Neurodegeneration: A Call for Population-Level Policy and Advancing the Exposome.

Babulal, GM.
2025,  
Human brain mapping

Cross-Sectional Comparison of Structural MRI Markers of Impairment in a Diverse Cohort of Older Adults.

Wisch, JK., et al.
2025,  
Nature communications

Human and mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome.

Yarbro, JM., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Role of tau versus TDP-43 pathology on medial temporal lobe atrophy in aging and Alzheimer's disease.

Wisse, LEM., et al.
2025,  
bioRxiv : the preprint server for biology

CHOIR improves significance-based detection of cell types and states from single-cell data.

Sant, C., et al.
2025,  
Human brain mapping

Head Motion in Diffusion Magnetic Resonance Imaging: Quantification, Mitigation, and Structural Associations in Large, Cross-Sectional Datasets Across the Lifespan.

Schilling, KG., et al.
2025,  
Nature communications

Automated cytometric gating with human-level performance using bivariate segmentation.

Chen, J., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Functional insight into East Asian-specific genetic risk loci for Alzheimer's disease.

Cho, M., et al.
2025,  
bioRxiv : the preprint server for biology

Synthetic Diffusion Tensor Imaging Maps Generated by 2D and 3D Probabilistic Diffusion Models: Evaluation and Applications.

Chattopadhyay, T., et al.
2025,  
Cancers

Advancing Pancreatic Cancer Prediction with a Next Visit Token Prediction Head on Top of Med-BERT.

He, J., et al.
2025,  
Journal of diabetes science and technology

Expert Clinical Interpretation of Continuous Glucose Monitor Reports From Individuals Without Diabetes.

Spartano, NL., et al.
2025,  
Bioinformatics (Oxford, England)

ESCARGOT: an AI agent leveraging large language models, dynamic graph of thoughts, and biomedical knowledge graphs for enhanced reasoning.

Matsumoto, N., et al.
2025,  
Nature communications

Drug repurposing for Alzheimer's disease and other neurodegenerative disorders.

Cummings, JL., et al.
2025,  
bioRxiv : the preprint server for biology

Gene module-trait network analysis uncovers cell type specific systems and genes relevant to Alzheimer's Disease.

de Paiva Lopes, K., et al.
2025,  
medRxiv : the preprint server for health sciences

A Novel Method to Disentangle Tightly Linked Risk and Resilience Genes for Brain Disorders: Application to Alzheimer's Disease.

Barnett, EJ., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Tau pathway-based gene analysis on PET identifies CLU and FYN in a Korean cohort.

Yi, D., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Locus coeruleus tau is linked to successive cortical tau accumulation.

Yi, D., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Transcriptome analysis of early- and late-onset Alzheimer's disease in Korean cohorts.

Han, S., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Moderation of midlife cognitive activity on tau-related cognitive impairment.

Ko, K., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Benchmarking of a multi-biomarker low-volume panel for Alzheimer's disease and related dementia research.

Ibanez, L., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

The association between adult child education and cognitive functioning among older parents: A cross-national comparison of diverse contexts.

Nichols, E., et al.
2025,  
Nature communications

Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility.

Gong, J., et al.
2025,  
Scientific reports

Association of genetic risk of Alzheimer's disease and cognitive function in two European populations.

Wang, B., et al.
2025,  
Brain : a journal of neurology

Amyloid-β predominant Alzheimer's disease neuropathologic change.

Kovacs, GG., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Association of APOE alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease neuroimaging markers.

Kulminski, AM., et al.
2025,  
medRxiv : the preprint server for health sciences

GWAS links APOE to neuropsychiatric symptoms in mild cognitive impairment and dementia.

Vattathil, SM., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Human herpesvirus-associated transposable element activation in human aging brains with Alzheimer's disease.

Feng, Y., et al.
2025,  
Nature communications

Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease.

Arnold, M., et al.
2025,  
bioRxiv : the preprint server for biology

BTS: scalable Bayesian Tissue Score for prioritizing GWAS variants and their functional contexts across omics data.

Kuksa, PP., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Comparing Alzheimer's genes in African, European, and Amerindian induced pluripotent stem cell-derived microglia.

Moura, S., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Plasma proteomic characterization of motoric cognitive risk and mild cognitive impairment.

Gomez, GT., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Blood biomarkers in Down syndrome: Facilitating Alzheimer's disease detection and monitoring.

Petersen, ME., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Differential associations of neighborhood disadvantage, race/ethnicity, and cognitive status with experiences of psychosocial distress in the HABS-HD cohort.

Rhoads, T., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Alzheimer's disease plasma biomarkers and physical functioning in a diverse sample of adults.

Knell, G., et al.
2025,  
Cell

Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes.

Guo, JL., et al.
2025,  
medRxiv : the preprint server for health sciences

Somatic and Stem Cell Bank to Study the Contribution of African Ancestry to Dementia: African iPSC Initiative.

Maina, MB., et al.
2025,  
Nature communications

regionalpcs improve discovery of DNA methylation associations with complex traits.

Eulalio, T., et al.
2025,  
Journal of medical imaging (Bellingham, Wash.)

Learning disentangled representations to harmonize connectome network measures.

Newlin, NR., et al.
2025,  
Alzheimer's research & therapy

Plasma phospho-tau217 as a predictive biomarker for Alzheimer's disease in a large south American cohort.

Pandey, N., et al.
2025,  
International journal of medical informatics

Modeling the impact of socioeconomic disparity, biological markers and environmental exposures on phenotypic age using mediation analysis and structural equation models.

Pala, D., et al.
2025,  
Radiology

Open-Source Large Language Models in Radiology: A Review and Tutorial for Practical Research and Clinical Deployment.

Savage, CH., et al.
2025,  
Computers in biology and medicine

Generalizable self-supervised learning for brain CTA in acute stroke.

Dong, Y., et al.
2025,  
Nature communications

Meta-EA: a gene-specific combination of available computational tools for predicting missense variant effects.

Katsonis, P.
2025,  
Genetic epidemiology

Enhancing Gene Expression Predictions Using Deep Learning and Functional Annotations.

Ramprasad, P., et al.
2025,  
Nature genetics

The impact of common and rare genetic variants on bradyarrhythmia development.

Weng, L., et al.
2025,  
IEEE transactions on medical imaging

Multi-Modal Diagnosis of Alzheimer's Disease Using Interpretable Graph Convolutional Networks.

Zhou, H., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association

Single-microglia transcriptomic transition network-based prediction and real-world patient data validation identifies ketorolac as a repurposable drug for Alzheimer's disease.

Xu, J., et al.
2025,  
NPJ Parkinson's disease

A network-based systems genetics framework identifies pathobiology and drug repurposing in Parkinson's disease.

Dou, L., et al.
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Artificial intelligence streamlines scientific discovery of drug-target interactions.

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The X chromosome's influences on the human brain.

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The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association

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The Dynamics of Cognitive Decline towards Alzheimer's Disease Progression: Results from ADSP-PHC's Harmonized Cognitive Composites.

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Comprehensive characterization of the transcriptional landscape in Alzheimer's disease (AD) brains.

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Liver function and Alzheimer's brain pathologies: A longitudinal study: Liver and Alzheimer's pathologies.

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Multi-Omics Analysis for Identifying Cell-Type-Specific Druggable Targets in Alzheimer's Disease.

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TrimNN: Characterizing cellular community motifs for studying multicellular topological organization in complex tissues.

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Biotin mitigates the development of manganese-induced, Parkinson's disease-related neurotoxicity in Drosophila and human neurons.

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Examination of MGMT as a risk gene for dementia in the Amish.

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Alzheimer's & dementia : the journal of the Alzheimer's Association

Sex and APOE ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease.

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bioRxiv : the preprint server for biology

Sex-specific Associations of Gene Expression with Alzheimer's Disease Neuropathology and Ante-mortem Cognitive Performance.

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Evaluating the association of APOE genotype and cognitive resilience in SuperAgers.

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Alzheimer's & dementia : the journal of the Alzheimer's Association

Association between dietary inflammatory index score and incident dementia.

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Differential Item Functioning and Clinical Utility of the Subjective Memory Complaints Questionnaire in a Multi-Ethnic Cohort.

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Characterization of plasma AT(N) biomarkers among a racial and ethnically diverse community-based cohort: an HABS-HD study.

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Alzheimer's & dementia (New York, N. Y.)

Predictive value and weight of factors associated with cognitive performance in Hispanics/Latinos enrolled in the Health and Aging Brain Study: Health Disparities.

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Patient stratification by genetic risk in Alzheimer's disease is only effective in the presence of phenotypic heterogeneity.

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Astrocyte Reactivity Polygenic Risk Score May Predict Cognitive Decline in Alzheimer's Disease.

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DNA methylation age from peripheral blood predicts progression to Alzheimer's disease, white matter disease burden, and cortical atrophy.

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Multi-modal Imaging-based Pseudotime Analysis of Alzheimer progression.

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Exploring the Early Adoption of Open AI among Laypeople and Technical Professionals: An Analysis of Twitter Conversations on #ChatGPT and #GPT3.

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Journal of electrocardiology

A novel electrocardiogram-based model for prediction of dementia-The Atherosclerosis Risk in Communities (ARIC) study.

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The Impact of Ancestry on Genome-Wide Association Studies.

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Connecting intermediate phenotypes to disease using multi-omics in heart failure.

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Enhancing the utility of polygenic scores in Alzheimer's disease through systematic curation and annotation.

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Deep5mC: Predicting 5-methylcytosine (5mC) methylation status using a deep learning transformer approach.

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Normative data for the CERAD verbal episodic memory tests in a sample of older illiterate Korean women.

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Deciphering novel mitochondrial signatures: multi-omics analysis uncovers cross-disease markers and oligodendrocyte pathways in Alzheimer's disease and glioblastoma.

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Alzheimer's & dementia (New York, N. Y.)

LD-informed deep learning for Alzheimer's gene loci detection using WGS data.

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