Investigating Causal Relations Between Risk Tolerance, Risky Behaviors, and Alzheimer’s Disease: A Bidirectional Two-Sample Mendelian Randomization Study.

Several studies have shown risky behaviors and risk tolerance are associated with Alzheimer’s disease. However, the underlying causality remains unclear. Risky behavior and risk tolerance may induce the onset of Alzheimer’s disease, and/or vulnerability to Alzheimer’s disease may result in more risky behaviors.