Amyloid and tau pathology are associated with cerebral blood flow in a mixed sample of nondemented older adults with and without vascular risk factors for Alzheimer's disease
Swinford, CG., et al.
2023,
Statistics in Medicine
Deep causal feature extraction and inference with neuroimaging genetic data
Yao, Y., et al.
2023,
JAMA neurology
Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults
Walters, S., et al.
2023,
Alzheimer Disease and Associated Disorders
Visuospatial and Verbal Memory Differences in Amish Individuals With Alzheimer Disease and Related Dementias
Prough, MB., et al.
2023,
Journal of the American Geriatrics Society
Can virtual reality travel help nursing home patients fulfill their bucket list?
Rodriguez, DK.
2023,
Nature Reviews. Cardiology
The bidirectional association between atrial fibrillation and myocardial infarction
Frederiksen, TC., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
The Early-Onset Alzheimer's Disease Whole-Genome Sequencing Project: Study design and methodology
Ray, NR., et al.
2023,
International Journal of Geriatric Psychiatry
Neuropsychiatric features in a multi-ethnic population with Alzheimer disease and mild cognitive impairment
Celis, K., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Ancestry-related differences in chromatin accessibility and gene expression of APOE ε4 are associated with Alzheimer's disease risk
Celis, K., et al.
2023,
Cell Reports
Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1
Lee, H., et al.
2023,
Cell Reports
Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions
Park, J., et al.
2023,
Human Molecular Genetics
Integrating GWAS summary statistics, individual-level genotypic and omic data to enhance the performance for large-scale trait imputation
Ren, J., et al.
2023,
Journal of Neuropathology and Experimental Neurology
LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry
Proceedings of the National Academy of Sciences of the United States of America
The liquid-to-solid transition of FUS is promoted by the condensate surface
Shen, Y., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
DNA from multiple viral species is associated with Alzheimer's disease risk
Tejeda, M., et al.
2023,
Genetic Epidemiology
Inference of causal metabolite networks in the presence of invalid instrumental variables with GWAS summary data
Chen, S., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Transcriptional risk scores in Alzheimer's disease: From pathology to cognition
Pyun, J., et al.
2023,
Journal of Clinical Medicine
Genetics of Alzheimer's Disease in the African American Population
Logue, MW., et al.
2023,
Cell Genomics
Multiset correlation and factor analysis enables exploration of multi-omics data
Brown, BC., et al.
2023,
Biology of Sex Differences
Sex differences in metabolic phenotype and hypothalamic inflammation in the 3xTg-AD mouse model of Alzheimer's disease
Robison, LS., et al.
2023,
BMJ open
Using community-based geographical information system (GIS) to recruit older Asian Americans in an Alzheimer's disease study
Lee, H., et al.
2023,
Neuron
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology
Sheehan, PW., et al.
2023,
Bioinformatics (Oxford, England)
ShinyBioHEAT: an interactive shiny app to identify phenotype driver genes in E.coli and B.subtilis
Wang, C., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Genome-wide methylomic regulation of multiscale gene networks in Alzheimer's disease
Wang, E., et al.
2023,
Journal of the American Geriatrics Society
Nursing home infection control strategies during the COVID-19 pandemic
Festa, N., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Identification of circRNAs linked to Alzheimer's disease and related dementias
Puri, S., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Obesity impacts the expression of Alzheimer's disease-related genes: The Framingham Heart Study
Charisis, S., et al.
2023,
International Journal of Stroke: Official Journal of the International Stroke Society
Pleiotropy analysis between lobar intracerebral hemorrhage and CSF β-amyloid highlights new and established associations
Marini, S., et al.
2023,
Human Molecular Genetics
Human herpesvirus 8 ORF57 protein is able to reduce TDP-43 pathology: network analysis identifies interacting pathways
Webber, CJ., et al.
2023,
Proceedings of the National Academy of Sciences of the United States of America
Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease
Cazzaro, S., et al.
2023,
medRxiv: The Preprint Server for Health Sciences
APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's Disease pathology
Chemparathy, A., et al.
2023,
Journal of Neuropathology and Experimental Neurology
The frequency and distribution of TDP-43 pathology in argyrophilic grain disease
Koga, S., et al.
2023,
Human Molecular Genetics
Genetic architecture of plasma Alzheimer disease biomarkers
Bradley, J., et al.
2023,
Science Translational Medicine
Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life
Walker, KA., et al.
2023,
HGG advances
Using GWAS summary data to impute traits for genotyped individuals
Ren, J., et al.
2023,
HGG advances
Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations
Horimoto, ARVR., et al.
2023,
Cell Metabolism
When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging
Mihaylova, MM., et al.
2023,
NPJ Regenerative medicine
Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer's disease
Siddiqui, T., et al.
2023,
NPJ Parkinson's disease
Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson's disease
Phillips, B., et al.
2023,
Acta Neuropathologica Communications
Diffuse argyrophilic grain disease with TDP-43 proteinopathy and neuronal intermediate filament inclusion disease: FTLD with mixed tau, TDP-43 and FUS pathologies
Koga, S., et al.
2023,
Science Translational Medicine
Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease
Sung, YJ., et al.
2023,
Brain: A Journal of Neurology
Reduced endothelial caveolin-1 underlies deficits in brain insulin signalling in type 2 diabetes
Shetti, AU., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Long-term blood pressure patterns in midlife and dementia in later life: Findings from the Framingham Heart Study
Kim, H., et al.
2023,
International Journal of Molecular Sciences
Stealth Liposomes Encapsulating a Potent ACAT1/SOAT1 Inhibitor F12511: Pharmacokinetic, Biodistribution, and Toxicity Studies in Wild-Type Mice and Efficacy Studies in Triple Transgenic Alzheimer's Disease Mice
De La Torre, AL., et al.
2023,
NeuroImage
Image harmonization: A review of statistical and deep learning methods for removing batch effects and evaluation metrics for effective harmonization
Hu, F., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Examination of potentially modifiable dementia risk factors across the adult life course: The Framingham Heart Study
Hwang, PH., et al.
2023,
Behavior Genetics
A Varying Coefficient Model to Jointly Test Genetic and Gene-Environment Interaction Effects
Zhou, Z., et al.
2023,
Acta Neuropathologica
Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals OTUD4 in shared dysregulated signatures across pathological subtypes
Fodder, K., et al.
2023,
Circulation. Cardiovascular Quality and Outcomes
Association Between Electrocardiographic Age and Cardiovascular Events in Community Settings: The Framingham Heart Study
Brant, LCC., et al.
2023,
Nature Human Behaviour
Identifying modifiable factors and their joint effect on dementia risk in the UK Biobank
Zhang, Y., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Identification of novel genes for age-at-onset of Alzheimer's disease by combining quantitative and survival trait analyses
Li, Y., et al.
2023,
Otolaryngology--Head and Neck Surgery: Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Association of Central Auditory Processing Dysfunction With Preclinical Alzheimer's Disease
Byun, MS., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Prevalence of dementia in India: National and state estimates from a nationwide study
Lee, J., et al.
2023,
Nature Medicine
Clonal hematopoiesis is associated with protection from Alzheimer's disease
Bouzid, H., et al.
2023,
Scientific Reports
Modeling of mitochondrial genetic polymorphisms reveals induction of heteroplasmy by pleiotropic disease locus 10398A>G
Smullen, M., et al.
2023,
Molecular Neurodegeneration
A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores
Kang, M., et al.
2023,
International Journal of Molecular Sciences
Cholesterol, Amyloid Beta, Fructose, and LPS Influence ROS and ATP Concentrations and the Phagocytic Capacity of HMC3 Human Microglia Cell Line
Muñoz Herrera, OM., et al.
2023,
Nature Communications
Leveraging football accelerometer data to quantify associations between repetitive head impacts and chronic traumatic encephalopathy in males
Daneshvar, DH., et al.
2023,
British Journal of Pharmacology
Hydrogen sulfide signalling in neurodegenerative diseases
Tripathi, SJ., et al.
2023,
The Journal of Clinical Investigation
Complement C3aR depletion reverses HIF-1α-induced metabolic impairment and enhances microglial response to Aβ pathology
Gedam, M., et al.
2023,
Alzheimer's Research & Therapy
Body mass index and two-year change of in vivo Alzheimer's disease pathologies in cognitively normal older adults
Lee, S., et al.
2023,
GeroScience
Sexual dimorphic metabolic and cognitive responses of C57BL/6 mice to Fisetin or Dasatinib and quercetin cocktail oral treatment
Fang, Y., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Profiling and predicting distinct tau progression patterns: An unsupervised data-driven approach to flortaucipir positron emission tomography
Tosun, D., et al.
2023,
Neurology
The Importance of Understanding Neighborhood Environments in Neurology Care
Kobau, R.
2023,
Angewandte Chemie (International Ed. in English)
Apolipoprotein E Recognizes Alzheimer's Disease Associated 3-O Sulfation of Heparan Sulfate
Mah, D., et al.
2023,
The Journal of Cell Biology
Autolysosomal exocytosis of lipids protect neurons from ferroptosis
Ralhan, I., et al.
2023,
Neurobiology of Disease
Amyloid beta peptides (Aβ) from Alzheimer's disease neuronal secretome induce endothelial activation in a human cerebral microvessel model
Shin, YJ., et al.
2023,
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Chronic, Mild Hypothermic Environmental Temperature Does Not Ameliorate Cognitive Deficits in an Alzheimer's Disease Mouse
McFadden, S., et al.
2023,
Brain: A Journal of Neurology
The pathotome and precision health
Younes, K.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews
Li, D., et al.
2023,
Aging and Disease
Serum Adiponectin and In Vivo Brain Amyloid Deposition in Cognitively Normal Older Adults: A Cohort Study
Kim, JW., et al.
2023,
Telemedicine Journal and E-Health: The Official Journal of the American Telemedicine Association
Decreasing Racial Disparities in Preventable Emergency Department Visits Through Hospital Health Information Technology Patient Engagement Functionalities
Wang, N.
2023,
Nature Neuroscience
Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease
Sun, N., et al.
2023,
GeroScience
Geroprotective interventions in the 3xTg mouse model of Alzheimer's disease
Sonsalla, MM.
2023,
Journal of the American Geriatrics Society
Factors affecting the recruitment of Hispanic/Latinx American older adults in clinical trials in the United States: A scoping review
Rodriguez, DK., et al.
2023,
Nature Aging
Targeting the biology of aging with mTOR inhibitors
Mannick, JB.
2023,
Neurobiology of Aging
Characterization of apathy-like behaviors in the 5xFAD mouse model of Alzheimer's disease
Keszycki, R., et al.
2023,
The Journal of Physiology
Regulation of metabolic health by dietary histidine in mice
Flores, V., et al.
2023,
British Journal of Cancer
Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state
Yu, W., et al.
2023,
Journal of Biomedical Informatics
HLA amino acid Mismatch-Based risk stratification of kidney allograft failure using a novel Machine learning algorithm
Dasariraju, S., et al.
2023,
Acta Neuropathologica
Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation
Filipello, F., et al.
2023,
Trends in Neurosciences
Moving beyond amyloid and tau to capture the biological heterogeneity of Alzheimer's disease
Young-Pearse, TL., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
APOE and immunity: Research highlights
Kloske, CM., et al.
2023,
Neurobiology of Aging
Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease
Seto, M., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Social enrichment on the job: Complex work with people improves episodic memory, promotes brain reserve, and reduces the risk of dementia
Coleman, ME., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans
Rajabli, F., et al.
2023,
Journal of Racial and Ethnic Health Disparities
Multiple Chronic Conditions and Disability among Vietnamese Older Adults: Results from the Vietnamese Aging and Care Survey (VACS)
Miyawaki, CE., et al.
2023,
Science Advances
Increased 3-O-sulfated heparan sulfate in Alzheimer's disease brain is associated with genetic risk gene HS3ST1
Wang, Z., et al.
2023,
Translational Psychiatry
Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study
Pan, M., et al.
2023,
Cancers
Genetic Variants Associated with Longitudinal Cognitive Performance in Older Breast Cancer Patients and Controls
Nudelman, K., et al.
2023,
Biology of Sex Differences
Menopause causes metabolic and cognitive impairments in a chronic cerebral hypoperfusion model of vascular contributions to cognitive impairment and dementia
Gannon, OJ., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Large-scale proteome and metabolome analysis of CSF implicates altered glucose and carbon metabolism and succinylcarnitine in Alzheimer's disease
Panyard, DJ., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Leveraging African American family connectors for Alzheimer's disease genomic studies
Byfield, G., et al.
2023,
Biology of Sex Differences
Sex differences in the effects of high fat diet on underlying neuropathology in a mouse model of VCID
Abi-Ghanem, C., et al.
2023,
Neuropathology: Official Journal of the Japanese Society of Neuropathology
Comments on an autopsy case of progressive supranuclear palsy treated with monoclonal antibody against tau
Koga, S., et al.
2023,
Scientific Reports
Transcriptomic and glycomic analyses highlight pathway-specific glycosylation alterations unique to Alzheimer's disease
Tang, X., et al.
2023,
Antioxidants (Basel, Switzerland)
Protective Roles of Hydrogen Sulfide in Alzheimer's Disease and Traumatic Brain Injury
Paul, BD.
2023,
Nature Communications
Functional variants identify sex-specific genes and pathways in Alzheimer's Disease
Bourquard, T., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Alzheimer's disease heterogeneity explained by polygenic risk scores derived from brain transcriptomic profiles
Chung, J., et al.
2023,
Cerebral Cortex (New York, N.Y.: 1991)
Heritability of cognitive abilities and regional brain structures in middle-aged to elderly East Asians
Lee, Y., et al.
2023,
Cell Stem Cell
Advancing cell therapy for neurodegenerative diseases
Temple, S.
2023,
Biological Psychiatry
Integrative Co-methylation Network Analysis Identifies Novel DNA Methylation Signatures and Their Target Genes in Alzheimer's Disease
Kim, JP., et al.
2023,
Nature Reviews. Neurology
A global view of the genetic basis of Alzheimer disease
Reitz, C., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains
Novotny, BC., et al.
2023,
Glia
The role of FUT8-catalyzed core fucosylation in Alzheimer's amyloid-β oligomer-induced activation of human microglia
Jin, L., et al.
2023,
Dementia (London, England)
Understanding Capacity and Optimizing Meaningful Engagement among Persons Living with Dementia
Kemp, CL., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Cost-effectiveness models for Alzheimer's disease and related dementias: IPECAD modeling workshop cross-comparison challenge
Handels, RLH., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Association of spermidine plasma levels with brain aging in a population-based study
Wortha, SM., et al.
2023,
Neuropsychology
Harmonizing the preclinical Alzheimer cognitive composite for multicohort studies
Hampton, OL., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Population-based discovery and Mendelian randomization analysis identify telmisartan as a candidate medicine for Alzheimer's disease in African Americans
Zhang, P., et al.
2023,
PLoS genetics
Combining Mendelian randomization and network deconvolution for inference of causal networks with GWAS summary data
Lin, Z., et al.
2023,
Neuropsychology
Cognitive domain harmonization and cocalibration in studies of older adults
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Blood levels of MCP-1 modulate the genetic risks of Alzheimer's disease mediated by HLA-DRB1 and APOE for Alzheimer's disease
Huang, J., et al.
2023,
Experimental & Molecular Medicine
Sex differences in the progression of glucose metabolism dysfunction in Alzheimer's disease
Park, J., et al.
2023,
Annals of Neurology
Aberrant GAP43 Gene Expression Is Alzheimer Disease Pathology-Specific
Pyun, J., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Measurement differences in the assessment of functional limitations for cognitive impairment classification across geographic locations
Nichols, E., et al.
2023,
Acta Neuropathologica Communications
Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease
Ali, M., et al.
2023,
Cell Reports
A plasma membrane-associated glycolytic metabolon is functionally coupled to KATP channels in pancreatic α and β cells from humans and mice
Ho, T., et al.
2023,
iScience
Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer's and coronary disease pathways
Wang, L., et al.
2023,
Nature Communications
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers
Brase, L., et al.
2023,
The World Journal of Men's Health
Responses to Many Anti-Aging Interventions Are Sexually Dimorphic
Bartke, A., et al.
2023,
Alzheimer's Research & Therapy
Higher performance for women than men in MRI-based Alzheimer's disease detection
Klingenberg, M., et al.
2023,
Science Translational Medicine
Lateral mammillary body neurons in mouse brain are disproportionately vulnerable in Alzheimer's disease
Huang, W., et al.
2023,
Brain: A Journal of Neurology
Brain functional connectivity mirrors genetic pleiotropy in psychiatric conditions
Moreau, CA., et al.
2023,
Genes
Interaction between KLOTHO-VS Heterozygosity and APOE ε4 Allele Predicts Rate of Cognitive Decline in Late-Onset Alzheimer's Disease
Chen, XR., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease
Bai, H., et al.
2023,
Scientific Reports
Sex-specific differences in the genetic and environmental effects on cardiac phenotypic variation assessed by echocardiography
Lin, H., et al.
2023,
Human Molecular Genetics
MATS: a novel multi-ancestry transcriptome-wide association study to account for heterogeneity in the effects of cis-regulated gene expression on complex traits
Knutson, KA.
2023,
American Journal of Human Genetics
Robust multivariable Mendelian randomization based on constrained maximum likelihood
Lin, Z., et al.
2023,
American Journal of Human Genetics
Evidence of epistasis in regions of long-range linkage disequilibrium across five complex diseases in the UK Biobank and eMERGE datasets
Singhal, P., et al.
2023,
Annals of Behavioral Medicine: A Publication of the Society of Behavioral Medicine
An Examination of the Longitudinal Relationship Between Cognitive Function and Physical Activity Among Older Breast Cancer Survivors in the Thinking and Living With Cancer Study
Tometich, DB., et al.
2023,
JAMA network open
Assessment of Risk Factors and Clinical Importance of Enlarged Perivascular Spaces by Whole-Brain Investigation in the Multi-Ethnic Study of Atherosclerosis
Charisis, S., et al.
2023,
JAMA network open
Evaluation of Plasma Biomarkers for A/T/N Classification of Alzheimer Disease Among Adults of Caribbean Hispanic Ethnicity
Honig, LS., et al.
2023,
American Journal of Physiology. Cell Physiology
Heparan sulfate proteoglycan in Alzheimer's disease: aberrant expression and functions in molecular pathways related to amyloid-β metabolism
Ozsan McMillan, I., et al.
2023,
NeuroImage
Deep neural network heatmaps capture Alzheimer's disease patterns reported in a large meta-analysis of neuroimaging studies
Wang, D., et al.
2023,
NeuroImage
Multiscale functional connectivity patterns of the aging brain learned from harmonized rsfMRI data of the multi-cohort iSTAGING study
Zhou, Z., et al.
2023,
NeuroImage
Applications of generative adversarial networks in neuroimaging and clinical neuroscience
Wang, R., et al.
2023,
EBioMedicine
The complex genetic architecture of Alzheimer's disease: novel insights and future directions
Andrews, SJ., et al.
2023,
Nature Genetics
Adjusting for common variant polygenic scores improves yield in rare variant association analyses
Jurgens, SJ., et al.
2023,
Nature Medicine
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease
Duperron, M., et al.
2023,
Neurobiology of Aging
Neural atrophy produced by AAV tau injections into hippocampus and anterior cortex of middle-aged mice
Tetlow, AM., et al.
2023,
eNeuro
Amyloid β-Peptide Effects on Glucose Regulation Are Dependent on Apolipoprotein E Genotype
Sung, JH., et al.
2023,
AJNR. American journal of neuroradiology
Incidental Findings from 16,400 Brain MRI Examinations of Research Volunteers
Rowley, PA., et al.
2023,
Acta Neuropathologica
Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts
McKee, AC., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Comorbidity-driven multi-modal subtype analysis in mild cognitive impairment of Alzheimer's disease
Katabathula, S., et al.
2023,
Journal of the American Geriatrics Society
Reappraising the public health benefits conferred by environmental policy: Considerations for an aging society
Festa, N., et al.
2023,
GeroScience
Resistance to mild cold stress is greater in both wild-type and long-lived GHR-KO female mice
Fang, Y., et al.
2023,
GeroScience
Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer's disease
Ballesteros-Álvarez, J., et al.
2023,
The Journal of Biological Chemistry
Coevolutionary signals in metabotropic glutamate receptors capture residue contacts and long-range functional interactions
Huh, E., et al.
2023,
Neurobiology of Disease
The role of innate lymphocytes in regulating brain and cognitive function
Altered cerebral blood flow in older adults with Alzheimer's disease: a systematic review
Swinford, CG., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Differential diagnosis of amnestic dementia patients based on an FDG-PET signature of autopsy-confirmed LATE-NC
Grothe, MJ., et al.
2023,
International Journal of Geriatric Psychiatry
Psychometric approaches to defining cognitive phenotypes in the Old Order Amish
Zaman, A., et al.
2023,
Alzheimer's Research & Therapy
Alzheimer's disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals
Pettigrew, C., et al.
2023,
JMIR public health and surveillance
The Effect of Activity Participation in Middle-Aged and Older People on the Trajectory of Depression in Later Life: National Cohort Study
Gao, Y., et al.
2023,
International Journal of Molecular Sciences
Co-Expression Network Analysis Identifies Molecular Determinants of Loneliness Associated with Neuropsychiatric and Neurodegenerative Diseases
Santiago, JA., et al.
2023,
Briefings in Bioinformatics
Integrative analysis of multi-omics and imaging data with incorporation of biological information via structural Bayesian factor analysis
Bao, J., et al.
2023,
Alzheimer's Research & Therapy
The relationship of insulin resistance and diabetes to tau PET SUVR in middle-aged to older adults
Ennis, GE., et al.
2023,
International Journal of Molecular Sciences
Integrin β3-Mediated Cell Senescence Associates with Gut Inflammation and Intestinal Degeneration in Models of Alzheimer's Disease
Tun, X., et al.
2023,
International Journal of Molecular Sciences
ACAT1/SOAT1 Blockade Suppresses LPS-Mediated Neuroinflammation by Modulating the Fate of Toll-like Receptor 4 in Microglia
Li, H., et al.
2023,
Neuron
Evolutionarily conserved regulators of tau identify targets for new therapies
Kim, J., et al.
2023,
International Journal of Molecular Sciences
Acute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity
Harned, TC., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
The Nairobi Declaration-Reducing the burden of dementia in low- and middle-income countries (LMICs): Declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs
Maestre, G., et al.
2023,
Journal of Medical Internet Research
Step Count, Self-reported Physical Activity, and Predicted 5-Year Risk of Atrial Fibrillation: Cross-sectional Analysis
Shapira-Daniels, A., et al.
2023,
JAMA network open
Association of Intensive vs Standard Blood Pressure Control With Regional Changes in Cerebral Small Vessel Disease Biomarkers: Post Hoc Secondary Analysis of the SPRINT MIND Randomized Clinical Trial
Rashid, T., et al.
2023,
Genes
Deep Learning-Based Feature Extraction with MRI Data in Neuroimaging Genetics for Alzheimer's Disease
Chakraborty, D., et al.
2023,
Molecular Psychiatry
African ancestry GWAS of dementia in a large military cohort identifies significant risk loci
Sherva, R., et al.
2023,
Nature Aging
Human striatal glia differentially contribute to AD- and PD-specific neurodegeneration
Xu, J., et al.
2023,
Annals of Neurology
Alzheimer's Disease Genetic Risk, Cognition, and Brain Aging in Midlife
Brenowitz, WD., et al.
2023,
Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
Evaluation of Tau Radiotracers in Chronic Traumatic Encephalopathy
Varlow, C.
2023,
Cell Research
mTOR gets greasy: lysosomal sensing of cholesterol
Bar-Peled, L.
2023,
Neuroimage. Reports
Deep Learning Based Detection of Enlarged Perivascular Spaces on Brain MRI
Rashid, T., et al.
2023,
Trends in Neurosciences
The foundation and architecture of precision medicine in neurology and psychiatry
Hampel, H., et al.
2023,
JAMA
Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease
Le Guen, Y., et al.
2023,
Genome Biology
FixItFelix: improving genomic analysis by fixing reference errors
Behera, S., et al.
2023,
Genome Medicine
TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation
Moutinho, M., et al.
2023,
Human Brain Mapping
Benchmarking the generalizability of brain age models: Challenges posed by scanner variance and prediction bias
Jirsaraie, RJ., et al.
2023,
BMC public health
Cohort Profile: Real-Time Insights of COVID-19 in India (RTI COVID-India)
Banerjee, J., et al.
2023,
Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology: Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference
Schnabel, RB., et al.
2023,
Proceedings of the National Academy of Sciences of the United States of America
Bias in machine learning models can be significantly mitigated by careful training: Evidence from neuroimaging studies
Wang, R., et al.
2023,
Scientific Reports
In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration
Ganne, A., et al.
2023,
Nature Communications
Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders
Cui, Y., et al.
2023,
Bioinformatics (Oxford, England)
LDmat: efficiently queryable compression of linkage disequilibrium matrices
Weiner, RJ., et al.
2023,
Science Advances
Chaperoning of specific tau structure by immunophilin FKBP12 regulates the neuronal resilience to extracellular stress
Jiang, L., et al.
2023,
CNS neuroscience & therapeutics
Enlarged perivascular spaces are associated with decreased brain tau deposition
Kang, KM., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Genetic variants in the SHISA6 gene are associated with delayed cognitive impairment in two family datasets
Ramos, J., et al.
2023,
Neurobiology of Aging
Investigation of the independent role of a rare APOE variant (L28P; APOE*4Pittsburgh) in late-onset Alzheimer disease
Fan, K., et al.
2023,
Molecular Psychiatry
Neuroimmune transcriptome changes in patient brains of psychiatric and neurological disorders
Chen, Y., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Higher Dietary Inflammatory Index scores are associated with brain MRI markers of brain aging: Results from the Framingham Heart Study Offspring cohort
Melo Van Lent, D., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
COVID-19 breakthrough infections and hospitalizations among vaccinated patients with dementia in the United States between December 2020 and August 2021
Wang, L., et al.
2023,
Molecular Psychiatry
Association of COVID-19 with endocarditis in patients with cocaine or opioid use disorders in the US
Wang, L., et al.
2023,
Journal of Pain and Symptom Management
Patient-Reported Quality Measures for Palliative Care: The Time is now
Walling, AM., et al.
2023,
American Journal of Public Health
Revisiting Patient Engagement and Empowerment Within the NIMHD Health Disparity Framework
Spencer, MRT.
2023,
The American Journal of Clinical Nutrition
Human fasting modulates macrophage function and upregulates multiple bioactive metabolites that extend lifespan in Caenorhabditis elegans: a pilot clinical study
Rhodes, CH., et al.
2023,
Clinics in Geriatric Medicine
Vascular and Nonvascular Mechanisms of Cognitive Impairment and Dementia
Kara, B., et al.
2023,
IEEE transactions on medical imaging
BrainGB: A Benchmark for Brain Network Analysis With Graph Neural Networks
Cui, H., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
The small HDL particle hypothesis of Alzheimer's disease
Martinez, AE., et al.
2023,
Human Molecular Genetics
Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson's disease genes
Li, J., et al.
2023,
Annual Review of Pathology
Genetics and Pathogenesis of Parkinson's Syndrome
Ye, H., et al.
2023,
BMC psychiatry
AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale
Fu, CHY., et al.
2023,
Journal of Medical Internet Research
Increasing Engagement in the Electronic Framingham Heart Study: Factorial Randomized Controlled Trial
Trinquart, L., et al.
2023,
Scientific Data
Deep phenotyping and genomic data from a nationally representative study on dementia in India
Lee, J., et al.
2023,
Neuron
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4
Gratuze, M., et al.
2023,
Alzheimer's Research & Therapy
A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice
Barendrecht, S., et al.
2023,
Neurology
Determinants of Perivascular Spaces in the General Population: A Pooled Cohort Analysis of Individual Participant Data
Evans, TE., et al.
2023,
Proceedings of the National Academy of Sciences of the United States of America
Anatomically interpretable deep learning of brain age captures domain-specific cognitive impairment
Yin, C., et al.
2023,
Scientific Reports
Explainable machine learning aggregates polygenic risk scores and electronic health records for Alzheimer's disease prediction
Gao, XR., et al.
2023,
Molecular Neurodegeneration
Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer's disease related proteins
Oatman, SR., et al.
2023,
Cell
Strength in diversity: Intra-cellular metabolite sharing enhances longevity
Lamming, DW.
2023,
Biostatistics (Oxford, England)
DeLIVR: a deep learning approach to IV regression for testing nonlinear causal effects in transcriptome-wide association studies
He, R., et al.
2023,
Medical Care
Hospital-based Health Information Technology Infrastructure: Evidence of Reduced Medicare Payments and Racial Disparities Among Patients With ADRD
Chen, J., et al.
2023,
Neurobiology of Disease
The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms
Felsky, D., et al.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Identification of the Aβ37/42 peptide ratio in CSF as an improved Aβ biomarker for Alzheimer's disease
Liu, L., et al.
2023,
Brain Research Bulletin
Posttranscriptional regulation of neurofilament proteins and tau in health and disease
Yuan, A.
2023,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4
Weiner, MW., et al.
2023,
Journal of Palliative Medicine
Revelations from a Machine Learning Analysis of the Most Downloaded Articles Published in Journal of Palliative Medicine 1999-2018
Tamang, S., et al.
2023,
Journal of Palliative Medicine
Palliative Care Is Proven
Periyakoil, VS.
2023,
Peptide Science (Hoboken, N.J.)
Current Peptide Vaccine and Immunotherapy Approaches Against Alzheimer's Disease
Parrocha, CMT.
2023,
Microcirculation (New York, N.Y.: 1994)
KIR channel regulation of electrical conduction along cerebrovascular endothelium: Enhanced modulation during Alzheimer's disease
Hakim, MA.
2023,
Radiology
Gadolinium Deposition in the Rat Brain Measured with Quantitative MRI versus Elemental Mass Spectrometry
Hua, N., et al.
2023,
Nature Biotechnology
A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
Zhou, Y., et al.
2023,
PLoS genetics
Using epigenomics to understand cellular responses to environmental influences in diseases
Wattacheril, JJ., et al.
2023,
Nature Neuroscience
Integrative transcriptomic analysis of the amyotrophic lateral sclerosis spinal cord implicates glial activation and suggests new risk genes
Humphrey, J., et al.
2023,
Medical Image Analysis
Signed graph representation learning for functional-to-structural brain network mapping
Tang, H., et al.
2023,
Journal of Alzheimer's disease: JAD
Polygenic Liability to Alzheimer's Disease Is Associated with a Wide Range of Chronic Diseases: A Cohort Study of 312,305 Participants
Wu, B., et al.
2023,
Methods in Molecular Biology (Clifton, N.J.)
Human-Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons and Glia for the Elucidation of Pathogenic Mechanisms in Alzheimer's Disease
Young, JE.
2023,
The Journal of Cardiovascular Aging
Protein homeostasis in the aged and diseased heart
Mainali, N., et al.
2023,
Journal of Alzheimer's disease: JAD
Wisconsin Healthcare Utilization Cost Among American Indians/Alaska Natives with and without Alzheimer's Disease and Related Dementias
Johnson, AL., et al.
2023,
Journal of Alzheimer's disease: JAD
Prodromal Glutamatergic Modulation with Riluzole Impacts Glucose Homeostasis and Spatial Cognition in Alzheimer's Disease Mice
Findley, CA., et al.
2023,
Frontiers in Aging Neuroscience
Health disparities in aging: Improving dementia care for Black women
Findley, CA., et al.
2023,
Brain Communications
Associations between self-reported sleep patterns and health, cognition and amyloid measures: results from the Wisconsin Registry for Alzheimer's Prevention
Du, L., et al.
2023,
The Journal of Prevention of Alzheimer's Disease
Understanding Online Registry Facilitators and Barriers Experienced by Black Brain Health Registry Participants: The Community Engaged Digital Alzheimer's Research (CEDAR) Study
Ashford, MT., et al.
2023,
Alzheimer's & Dementia (New York, N. Y.)
Alzheimer's disease drug development pipeline: 2023
Cummings, J., et al.
2023,
Frontiers in Cardiovascular Medicine
Association of lifestyle with deep learning predicted electrocardiographic age
Zhang, C., et al.
2023,
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Polygenic resilience score may be sensitive to preclinical Alzheimer's disease changes
Eissman, JM., et al.
2023,
Journal of Alzheimer's disease: JAD
A Surface-Based Federated Chow Test Model for Integrating APOE Status, Tau Deposition Measure, and Hippocampal Surface Morphometry
Wu, J., et al.
2023,
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
Exploring Automated Machine Learning for Cognitive Outcome Prediction from Multimodal Brain Imaging using STREAMLINE
Wang, X., et al.
2023,
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
Comparing Amyloid Imaging Normalization Strategies for Alzheimer's Disease Classification using an Automated Machine Learning Pipeline
Tong, B., et al.
2023,
Frontiers in Molecular Biosciences
Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling
Minaya, MA., et al.
2023,
Neuroendocrinology
Changes in Corticotropin-Releasing Factor Receptor Type 1, Co-Expression with Tyrosine Hydroxylase and Oxytocin Neurons, and Anxiety-Like Behaviors across the Postpartum Period in Mice
De Guzman, RM., et al.
2023,
Clinical Gerontologist
A scoping review of dementia caregiving for Korean Americans and recommendations for future research
Ta Park, VM., et al.
2023,
Journal of Alzheimer's disease: JAD
Low Ankle-Brachial Index Relates to Alzheimer-Signature Cerebral Glucose Metabolism in Cognitively Impaired Older Adults
Moon, SW., et al.
2023,
Neuroepidemiology
Estimating the Prevalence of Dementia in India Using a Semi-Supervised Machine Learning Approach
Jin, H., et al.
2023,
Journal of Sleep Disorders & Therapy
Strategies to Engage Blacks in Sleep Medicine: Lessons Learned from Three Studies Applying Community-Based Participatory Research Principles
Rogers, A., et al.
2022
2022,
NPJ digital medicine
Factors associated with long-term use of digital devices in the electronic Framingham Heart Study
Pathiravasan, CH., et al.
2022,
Alzheimer's Research & Therapy
Synergistic interaction of high blood pressure and cerebral beta-amyloid on tau pathology
Kim, T., et al.
2022,
Journal of Medical Internet Research
Association Between Acoustic Features and Neuropsychological Test Performance in the Framingham Heart Study: Observational Study
Ding, H., et al.
2022,
Translational Psychiatry
The impact of increasing levels of blood C-reactive protein on the inflammatory loci SPI1 and CD33 in Alzheimer's disease
Huang, J., et al.
2022,
Brain: A Journal of Neurology
Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan
Luo, J., et al.
2022,
Genome Medicine
Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes
Yang, C., et al.
2022,
International Journal of Molecular Sciences
Physiological Consequences of Targeting 14-3-3 and Its Interacting Partners in Neurodegenerative Diseases
Ganne, A., et al.
2022,
Cells
Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females
Pan, AL., et al.
2022,
Biomedicines
Microglia and Cholesterol Handling: Implications for Alzheimer's Disease
Muñoz Herrera, OM.
2022,
JAMA network open
Development and Validation of a Prediction Model for Need for Massive Transfusion During Surgery Using Intraoperative Hemodynamic Monitoring Data
Lee, SM., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Progranulin mutations in clinical and neuropathological Alzheimer's disease
Vardarajan, BN., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population
Godrich, D., et al.
2022,
Nature
Medin co-aggregates with vascular amyloid-β in Alzheimer's disease
Wagner, J., et al.
2022,
European journal of human genetics: EJHG
Exploiting family history in aggregation unit-based genetic association tests
Wang, Y., et al.
2022,
Molecular & cellular proteomics: MCP
Glycoproteomics Landscape of Asymptomatic and Symptomatic Human Alzheimer's Disease Brain
Suttapitugsakul, S., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [11 C]UCB-J
Mecca, AP., et al.
2022,
Aging Cell
SIRT3 deficiency decreases oxidative metabolism capacity but increases lifespan in male mice under caloric restriction
Dhillon, RS., et al.
2022,
Population Health Management
Strengthening the Public Health Partnership and Telehealth Infrastructure to Reduce Health Care Disparities
Chen, J., et al.
2022,
Genetic Epidemiology
Statistical power of transcriptome-wide association studies
He, R., et al.
2022,
Journal of Computational Biology: A Journal of Computational Molecular Cell Biology
Multimodal Genotype and Phenotype Data Integration to Improve Partial Data-Based Longitudinal Prediction
Ganjdanesh, A., et al.
2022,
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine
Consistency of Graph Theoretical Measurements of Alzheimer's Disease Fiber Density Connectomes Across Multiple Parcellation Scales
Xu, F., et al.
2022,
Genetic Epidemiology
Genetic heterogeneity: Challenges, impacts, and methods through an associative lens
Woodward, AA., et al.
2022,
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine
Preference Matrix Guided Sparse Canonical Correlation Analysis for Genetic Study of Quantitative Traits in Alzheimer's Disease
Sha, J., et al.
2022,
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine
Mediation Analysis and Mixed-Effects Models for the Identification of Stage-specific Imaging Genetics Patterns in Alzheimer's Disease
Pala, D., et al.
2022,
Nature Genetics
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease
Holstege, H., et al.
2022,
Biomolecules
Heparan Sulfate Proteoglycans in Tauopathy
Zhu, Y., et al.
2022,
Cell Reports
Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease
Xu, J., et al.
2022,
Science Advances
Generative and reproducible benchmarks for comprehensive evaluation of machine learning classifiers
Orzechowski, P.
2022,
Scientific Reports
The association between eicosanoids and incident atrial fibrillation in the Framingham Heart Study
Kornej, J., et al.
2022,
Journal of Neuroinflammation
Neuroimmune proteins can differentiate between tauopathies
Cherry, JD., et al.
2022,
Briefings in Bioinformatics
Integrating multi-omics summary data using a Mendelian randomization framework
Jin, C., et al.
2022,
Genome Medicine
Towards elucidating disease-relevant states of neurons and glia by CRISPR-based functional genomics
Leng, K.
2022,
Cells
Intranasal Peptide Therapeutics: A Promising Avenue for Overcoming the Challenges of Traditional CNS Drug Development
Bose, M., et al.
2022,
JAMA
Development of a Prediction Model for Ascending Aortic Diameter Among Asymptomatic Individuals
Pirruccello, JP., et al.
2022,
IEEE transactions on neural networks and learning systems
Contrastive Brain Network Learning via Hierarchical Signed Graph Pooling Model
Tang, H., et al.
2022,
Cerebral Cortex (New York, N.Y.: 1991)
Co-expression network analysis of frontal cortex during the progression of Alzheimer's disease
Beck, JS., et al.
2022,
Cell Reports
Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function
Pratt, KJB., et al.
2022,
NPJ digital medicine
Multimodal machine learning in precision health: A scoping review
Kline, A., et al.
2022,
Toxins
Omics Methods in Toxins Research-A Toolkit to Drive the Future of Scientific Inquiry
Romano, JD.
2022,
Neuron
Microglial efferocytosis: Diving into the Alzheimer's disease gene pool
Romero-Molina, C., et al.
2022,
Nature
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes
Blanchard, JW., et al.
2022,
Journal of Geriatric Psychiatry and Neurology
Towards Defining the Neuroanatomical Basis of Late-Onset Psychiatric Symptoms
Barker, MS., et al.
2022,
Acta Neuropathologica
Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers
Jansen, IE., et al.
2022,
Nature
Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid
Drieu, A., et al.
2022,
Medical Care
Identifying Medicare Beneficiaries With Delirium
Moura, LMVR., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease
Jun, GR., et al.
2022,
Neurobiology of Disease
Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities
Katsumata, Y., et al.
2022,
Journal of Psychiatric Research
Association of autoimmune diseases with Alzheimer's disease: A mendelian randomization study
Yeung, CHC., et al.
2022,
Molecular Psychiatry
Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning
Lahti, J., et al.
2022,
Molecular & cellular proteomics: MCP
Regio-Specific N-Glycome and N-Glycoproteome Map of the Elderly Human Brain With and Without Alzheimer's Disease
Tena, J., et al.
2022,
Autophagy
Autolysosomal acidification failure as a primary driver of Alzheimer disease pathogenesis
Lee, J.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Crosswalk between the Mini-Mental State Examination and the Telephone Interview for Cognitive Status (TICS-27/30/40)
Hlávka, JP., et al.
2022,
Proceedings of the National Academy of Sciences of the United States of America
Understanding the roles of central and autonomic activity during sleep in the improvement of working memory and episodic memory
Chen, P., et al.
2022,
The American Journal of Geriatric Psychiatry: Official Journal of the American Association for Geriatric Psychiatry
An HIT-Supported Care Coordination Framework for Reducing Structural Racism and Discrimination for Patients With ADRD
Chen, J., et al.
2022,
EClinicalMedicine
Different loneliness types, cognitive function, and brain structure in midlife: Findings from the Framingham Heart Study
Tao, Q., et al.
2022,
Acta Neuropathologica Communications
Artificial intelligence-derived neurofibrillary tangle burden is associated with antemortem cognitive impairment
Marx, GA., et al.
2022,
Translational Neurodegeneration
Myelin repair in Alzheimer's disease: a review of biological pathways and potential therapeutics
Hirschfeld, LR., et al.
2022,
Molecular Neurodegeneration
The Golgi apparatus: Site for convergence of COVID-19 brain fog and Alzheimer's disease?
Wang, Y.
2022,
Nature Communications
Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model
Rickner, HD., et al.
2022,
Human Molecular Genetics
Human Molecular Genetics Review Issue 2022
Cheng, F.
2022,
Human Molecular Genetics
Quantitative trait locus (xQTL) approaches identify risk genes and drug targets from human non-coding genomes
Bykova, M., et al.
2022,
Biochemistry
Ganglioside-Enriched Phospholipid Vesicles Induce Cooperative Aβ Oligomerization and Membrane Disruption
Saha, J., et al.
2022,
Cell Reports. Medicine
Transcriptomics-based network medicine approach identifies metformin as a repurposable drug for atrial fibrillation
Lal, JC., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains
Novotny, BC., et al.
2022,
Nature Communications
Spatial snapshots of amyloid precursor protein intramembrane processing via early endosome proteomics
Park, H., et al.
2022,
Nature Communications
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis
Boland, S., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Whole genome sequencing-based copy number variations reveal novel pathways and targets in Alzheimer's disease
Ming, C., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
The National Institute on Aging Late-Onset Alzheimer's Disease Family Based Study: A resource for genetic discovery
Reyes-Dumeyer, D., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Identifying differential regulatory control of APOE ɛ4 on African versus European haplotypes as potential therapeutic targets
Nuytemans, K., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance
Gao, Y., et al.
2022,
Movement Disorders: Official Journal of the Movement Disorder Society
Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy
Hopfner, F., et al.
2022,
Molecular Psychiatry
Cognitive performance protects against Alzheimer's disease independently of educational attainment and intelligence
Hu, Y., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk
Hu, Y., et al.
2022,
Nature Biotechnology
DIALOGUE maps multicellular programs in tissue from single-cell or spatial transcriptomics data
Jerby-Arnon, L.
2022,
Neurobiology of Aging
RNASE6 is a novel modifier of APOE-ε4 effects on cognition
Seto, M., et al.
2022,
Preventive Medicine
Rural and urban disparities in potentially preventable hospitalizations among US patients with Alzheimer's Disease and Related Dementias: Evidence of hospital-based telehealth and enabling services
Wang, N., et al.
2022,
Acta Neuropathologica
Rainwater Charitable Foundation criteria for the neuropathologic diagnosis of progressive supranuclear palsy
Roemer, SF., et al.
2022,
Journal of Palliative Medicine
Symptom Control Research
Periyakoil, VS., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Moving beyond disclosure: Stages of care in preclinical Alzheimer's disease biomarker testing
Ketchum, FB., et al.
2022,
Current Opinion in Physiology
Mechanisms Controlling Selective Elimination of Damaged Lysosomes
Hoyer, MJ., et al.
2022,
Epilepsy Research
A replicable, open-source, data integration method to support national practice-based research & quality improvement systems
Fernandes, M., et al.
2022,
PLoS computational biology
Deep mendelian randomization: Investigating the causal knowledge of genomic deep learning models
Malina, S., et al.
2022,
Human Genetics
Genome interpretation using in silico predictors of variant impact
Katsonis, P., et al.
2022,
Computer Science & Information Technology
Tensor-Based Multi-Modality Feature Selection and Regression for Alzheimer's Disease Diagnosis
Yu, J., et al.
2022,
Genome Research
Mosaic loss of Chromosome Y in aged human microglia
Vermeulen, MC., et al.
2022,
Psychiatry and Clinical Neurosciences
Spouse bereavement and brain pathologies: A propensity score matching study
Kim, JW., et al.
2022,
Neurology. Genetics
A Fast and Robust Strategy to Remove Variant-Level Artifacts in Alzheimer Disease Sequencing Project Data
Belloy, ME., et al.
2022,
Nature
Stroke genetics informs drug discovery and risk prediction across ancestries
Mishra, A., et al.
2022,
BMC bioinformatics
Deep multiview learning to identify imaging-driven subtypes in mild cognitive impairment
Feng, Y., et al.
2022,
Human Molecular Genetics
Genotype-phenotype correlation of T-cell subtypes reveals senescent and cytotoxic genes in Alzheimer's disease
Dressman, D., et al.
2022,
BMC bioinformatics
Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data
Mai, H., et al.
2022,
Scientific Reports
Molecular pathways enhance drug response prediction using transfer learning from cell lines to tumors and patient-derived xenografts
Tang, Y., et al.
2022,
Neurogenetics
Whole-exome sequencing reveals PSEN1 and ATP7B combined variants as a possible cause of early-onset Lewy body dementia: a case study of genotype-phenotype correlation
Tábuas-Pereira, M., et al.
2022,
Alzheimer's Research & Therapy
Distinct sex-specific DNA methylation differences in Alzheimer's disease
C Silva, T., et al.
2022,
Human Genetics
The promise of automated machine learning for the genetic analysis of complex traits
Manduchi, E., et al.
2022,
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Association Between Mediterranean Diet and Functional Status in Older Adults: A Longitudinal Study Based on the Washington Heights-Inwood Columbia Aging Project
Guo, J., et al.
2022,
Trends in genetics: TIG
'Fly-ing' from rare to common neurodegenerative disease mechanisms
Ma, M., et al.
2022,
Neurobiology of Aging
Amyloid, cerebrovascular disease, and neurodegeneration biomarkers are associated with cognitive trajectories in a racially and ethnically diverse, community-based sample
Lao, PJ., et al.
2022,
Human Molecular Genetics
Genetic architecture of RNA editing regulation in Alzheimer's disease across diverse ancestral populations
Gardner, OK., et al.
2022,
Genes
Mining High-Level Imaging Genetic Associations via Clustering AD Candidate Variants with Similar Brain Association Patterns
Wu, R., et al.
2022,
Proceedings of the National Academy of Sciences of the United States of America
Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation
Saroja, SR., et al.
2022,
Science (New York, N.Y.)
Functional regulatory variants implicate distinct transcriptional networks in dementia
Cooper, YA., et al.
2022,
Bioinformatics (Oxford, England)
Omnibus and Robust Deconvolution Scheme for Bulk RNA Sequencing Data Integrating Multiple Single-Cell Reference Sets and Prior Biological Knowledge
Chen, C., et al.
2022,
Nature Communications
Cross-tissue analysis of blood and brain epigenome-wide association studies in Alzheimer's disease
C Silva, T., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Differential diagnosis of amnestic dementia patients based on an FDG-PET signature of autopsy-confirmed LATE-NC
Grothe, MJ., et al.
2022,
Human Molecular Genetics
Scalable approaches for functional analyses of whole-genome sequencing non-coding variants
Kuksa, PP., et al.
2022,
Brain: A Journal of Neurology
Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI
Yang, Y., et al.
2022,
Neuropsychology
Cognitive domain harmonization and cocalibration in studies of older adults
Mukherjee, S., et al.
2022,
BMC medical genomics
Identifying genetic markers enriched by brain imaging endophenotypes in Alzheimer's disease
Kim, M., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau
Frank, B., et al.
2022,
Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism
Genome-wide association study of brain arteriolosclerosis
Shade, LM., et al.
2022,
Journal of Alzheimer's disease: JAD
The Advisory Group on Risk Evidence Education for Dementia: Multidisciplinary and Open to All
Rosen, AC., et al.
2022,
Brain: A Journal of Neurology
Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease
Eissman, JM., et al.
2022,
Translational Psychiatry
Polygenic resilience scores capture protective genetic effects for Alzheimer's disease
Hou, J., et al.
2022,
Human Molecular Genetics
Accounting for nonlinear effects of gene expression identifies additional associated genes in transcriptome-wide association studies
Lin, Z., et al.
2022,
Cells
A Method for Bridging Population-Specific Genotypes to Detect Gene Modules Associated with Alzheimer's Disease
Dai, Y., et al.
2022,
HGG advances
The genetic architecture of Alzheimer disease risk in the Ohio and Indiana Amish
Osterman, MD., et al.
2022,
Nucleic Acids Research
EPIMUTESTR: a nearest neighbor machine learning approach to predict cancer driver genes from the evolutionary action of coding variants
Parvandeh, S., et al.
2022,
PLoS genetics
A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer's Disease in African Ancestry
Rajabli, F., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Contribution of Alzheimer's biomarkers and risk factors to cognitive impairment and decline across the Alzheimer's disease continuum
Tosun, D., et al.
2022,
JAMA neurology
Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease
Le Guen, Y., et al.
2022,
Acta Neuropathologica
FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer's disease
Lee, AJ., et al.
2022,
Stem Cell Research
Generation of two iPSC lines (UMi038-A & UMi039-A) from siblings bearing an Alzheimer's disease-associated variant in SORL1
DeRosa, BA., et al.
2022,
Annals of Neurology
Association of Apolipoprotein E ɛ4 Allele with Enlarged Perivascular Spaces
Pinheiro, A., et al.
2022,
Brain: A Journal of Neurology
Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate
Mishra, A., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women
Chung, J., et al.
2022,
Biological Psychiatry
Integrative Co-methylation Network Analysis Identifies Novel DNA Methylation Signatures and Their Target Genes in Alzheimer's Disease
Kim, JP., et al.
2022,
Cell
Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
Tcw, J., et al.
2022,
American Journal of Human Genetics
Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss
Trpchevska, N., et al.
2022,
BMC genomics
Integrative analysis of summary data from GWAS and eQTL studies implicates genes differentially expressed in Alzheimer's disease
Lee, B., et al.
2022,
American Journal of Human Genetics
Integration of rare expression outlier-associated variants improves polygenic risk prediction
Smail, C., et al.
2022,
Biological Psychiatry. Cognitive Neuroscience and Neuroimaging
Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes
Le Grand, Q., et al.
2022,
Molecular Psychiatry
Admixture Mapping of Alzheimer's disease in Caribbean Hispanics identifies a new locus on 22q13.1
Kizil, C., et al.
2022,
Nature Protocols
Chromatin accessibility profiling by ATAC-seq
Grandi, FC., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease
Horgusluoglu, E., et al.
2022,
Aging Cell
Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells
You, Y., et al.
2022,
Cells
Single Cell/Nucleus Transcriptomics Comparison in Zebrafish and Humans Reveals Common and Distinct Molecular Responses to Alzheimer's Disease
Cosacak, MI., et al.
2022,
Neurology
Genetic Risk, Midlife Life's Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study
Tin, A., et al.
2022,
Nucleic Acids Research
MethReg: estimating the regulatory potential of DNA methylation in gene transcription
Silva, TC., et al.
2022,
Scientific Reports
Genome-wide association of polygenic risk extremes for Alzheimer's disease in the UK Biobank
Gouveia, C., et al.
2022,
Journal of Neuroinflammation
High-fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner
Gannon, OJ., et al.
2022,
Brain: A Journal of Neurology
Antemortem plasma phosphorylated tau (181) predicts Alzheimer's disease neuropathology and regional tau at autopsy
Morrison, MS., et al.
2022,
JAMA psychiatry
Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression
Wen, J., et al.
2022,
Genome Research
A general calculus of fitness landscapes finds genes under selection in cancers
Hsu, T., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Genetic variants in the SHISA6 gene are associated with delayed cognitive impairment in two family datasets
Ramos, J., et al.
2022,
European Journal of Neurology
Rare variants in TP73 in a frontotemporal dementia cohort link this gene with primary progressive aphasia phenotypes
Tábuas-Pereira, M., et al.
2022,
Current Protocols
Molecular Quantitative Trait Locus Mapping in Human Complex Diseases
Olayinka, OA., et al.
2022,
Annals of Clinical and Translational Neurology
Correlation of plasma and neuroimaging biomarkers in Alzheimer's disease
Brickman, AM., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Current directions in tau research: Highlights from Tau 2020
Sexton, C., et al.
2022,
Cells
Identifying Blood Biomarkers for Dementia Using Machine Learning Methods in the Framingham Heart Study
Lin, H., et al.
2022,
Neurology
Multiple Cortical to Striatal Accumulation Trajectories of β-Amyloid: Do All Roads Lead to Rome?
Vogel, JW.
2022,
Neuron
ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias
Martens, YA., et al.
2022,
Journal of Medical Internet Research
Associations Between the Digital Clock Drawing Test and Brain Volume: Large Community-Based Prospective Cohort (Framingham Heart Study)
Yuan, J., et al.
2022,
Scientific Reports
Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90
Heath, L., et al.
2022,
Med (New York, N.Y.)
Integrating functional genomics with genetics to understand the biology of ALS and FTD
Cruchaga, C.
2022,
Communications Biology
Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels
Sarnowski, C., et al.
2022,
American Journal of Human Genetics
Family history aggregation unit-based tests to detect rare genetic variant associations with application to the Framingham Heart Study
Wang, Y., et al.
2022,
Circulation
Circulating Metabolome and White Matter Hyperintensities in Women and Men
Sliz, E., et al.
2022,
Neurobiology of Disease
Soluble TREM2: Innocent bystander or active player in neurological diseases?
Filipello, F., et al.
2022,
Journal of the International Neuropsychological Society: JINS
Midlife Vascular Factors and Prevalence of Mild Cognitive Impairment in Late-Life in Mexico
Arce Rentería, M., et al.
2022,
Nature Genetics
New insights into the genetic etiology of Alzheimer's disease and related dementias
Bellenguez, C., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Replication study of AD-associated rare variants
Neupane, A., et al.
2022,
Genome Research
An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns
Jin, B., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Midlife lipid and glucose levels are associated with Alzheimer's disease
Zhang, X., et al.
2022,
Briefings in Bioinformatics
Deep learning-based identification of genetic variants: application to Alzheimer's disease classification
Jo, T., et al.
2022,
Acta Neuropathologica Communications
Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease
Chen, H., et al.
2022,
NeuroImage
Deep learning for Alzheimer's disease: Mapping large-scale histological tau protein for neuroimaging biomarker validation
Ushizima, D., et al.
2022,
NAR genomics and bioinformatics
FILER: a framework for harmonizing and querying large-scale functional genomics knowledge
Kuksa, PP., et al.
2022,
Journal of magnetic resonance imaging: JMRI
Deep Generative Medical Image Harmonization for Improving Cross-Site Generalization in Deep Learning Predictors
Bashyam, VM., et al.
2022,
Alzheimer's Research & Therapy
Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease
Panitch, R., et al.
2022,
Social Science & Medicine (1982)
Longitudinal associations between racial discrimination and hippocampal and white matter hyperintensity volumes among older Black adults
Zahodne, LB., et al.
2022,
Alzheimer's Research & Therapy
Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping
Belloy, ME., et al.
2022,
Medical Image Analysis
Embracing the disharmony in medical imaging: A Simple and effective framework for domain adaptation
Wang, R., et al.
2022,
Aging Cell
Aging-related cell type-specific pathophysiologic immune responses that exacerbate disease severity in aged COVID-19 patients
Hou, Y., et al.
2022,
Current Opinion in Structural Biology
Interpretable artificial intelligence and exascale molecular dynamics simulations to reveal kinetics: Applications to Alzheimer's disease
Martin, W., et al.
2022,
Neurology. Genetics
Confirming Pathogenicity of the F386L PSEN1 Variant in a South Asian Family With Early-Onset Alzheimer Disease
Eger, SJ., et al.
2022,
Genetic Epidemiology
Precisely modeling zero-inflated count phenotype for rare variants
Fan, Q., et al.
2022,
Neurobiology of Aging
Cognitive reserve proxies, Alzheimer pathologies, and cognition
Ko, K., et al.
2022,
BMC genomics
Genome-Wide association study of quantitative biomarkers identifies a novel locus for alzheimer's disease at 12p12.1
Lee, B., et al.
2022,
European Journal of Hybrid Imaging
Regional uptakes from early-frame amyloid PET and 18F-FDG PET scans are comparable independent of disease state
Myoraku, A., et al.
2022,
Molecular Neurodegeneration
Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains
Bigley, TM., et al.
2022,
Biomedicines
Phenotypic Heterogeneity among GBA p.R202X Carriers in Lewy Body Spectrum Disorders
Napolioni, V., et al.
2022,
Alzheimer's Research & Therapy
Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer's disease
Fang, J., et al.
2022,
Molecular Neurodegeneration
Challenge accepted: uncovering the role of rare genetic variants in Alzheimer's disease
Khani, M., et al.
2022,
Neurology
Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population
Angevaare, MJ., et al.
2022,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Harmonizing neuropsychological assessment for mild neurocognitive disorders in Europe
Boccardi, M., et al.
2022,
Alzheimer's & Dementia (New York, N. Y.)
The Alzheimer's Cell Atlas (TACA): A single-cell molecular map for translational therapeutics accelerator in Alzheimer's disease
Zhou, Y., et al.
2022,
Journal of Alzheimer's disease: JAD
Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease
Kuksa, PP., et al.
2022,
Journal of Alzheimer's disease: JAD
Polygenic Risk Scores in Alzheimer's Disease Genetics: Methodology, Applications, Inclusion, and Diversity
Clark, K., et al.
2022,
Frontiers in Molecular Neuroscience
Cell type-specific histone acetylation profiling of Alzheimer's disease subjects and integration with genetics
A knowledge graph-based disease-gene prediction system using multi-relational graph convolution networks
Gao, Z., et al.
2022,
PloS One
SPARE-Tau: A flortaucipir machine-learning derived early predictor of cognitive decline
Toledo, JB., et al.
2022,
PloS One
Gut microbiome alterations in preclinical Alzheimer's disease
Jung, JH., et al.
2022,
Alzheimer's & Dementia (Amsterdam, Netherlands)
Immunity gene IFITM3 variant: Relation to cognition and Alzheimer's disease pathology
Pyun, J., et al.
2022,
Alzheimer's & Dementia (Amsterdam, Netherlands)
Network-wise concordance of multimodal neuroimaging features across the Alzheimer's disease continuum
Stocks, J., et al.
2022,
PloS One
Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk
Ali, M., et al.
2022,
Journal of Alzheimer's disease: JAD
Comparative Analysis of Alzheimer's Disease Cerebrospinal Fluid Biomarkers Measurement by Multiplex SOMAscan Platform and Immunoassay-Based Approach
Timsina, J., et al.
2022,
Human Brain Mapping
Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years
Dima, D., et al.
2022,
Nature Genetics
Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies
Lopes, KdP., et al.
2022,
Human Brain Mapping
Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years
Frangou, S., et al.
2022,
Acta Neuropathologica
Genome-wide association study and functional validation implicates JADE1 in tauopathy
Farrell, K., et al.
2022,
Frontiers in Neurology
Exome Sequencing of a Portuguese Cohort of Frontotemporal Dementia Patients: Looking Into the ALS-FTD Continuum
Tábuas-Pereira, M., et al.
2022,
Brain Communications
Disentangling Alzheimer's disease neurodegeneration from typical brain ageing using machine learning
Hwang, G., et al.
2022,
Frontiers in Psychiatry
Associations of digital neuro-signatures with molecular and neuroimaging measures of brain resilience: The altoida large cohort study
Seixas, AA., et al.
2022,
Journal of Alzheimer's disease: JAD
Measuring Subjective Cognitive Decline in Older Adults: Harmonization Between the Cognitive Change Index and the Measurement of Everyday Cognition Instruments
Wells, LF., et al.
2022,
Journal of Alzheimer's disease: JAD
Late-Life Physical Activities Moderate the Relationship of Amyloid-β Pathology with Neurodegeneration in Individuals Without Dementia
Sohn, BK., et al.
2022,
Journal of Alzheimer's disease: JAD
Functional Neural Correlates of Semantic Fluency Task Performance in Mild Cognitive Impairment and Alzheimer's Disease: An FDG-PET Study
Ahn, H., et al.
2021
2021,
Proceedings of the National Academy of Sciences of the United States of America
Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer's disease-associated genes
Moulton, MJ., et al.
2021,
Scientific Reports
Using imputation to provide harmonized longitudinal measures of cognition across AIBL and ADNI
Shishegar, R., et al.
2021,
Translational Psychiatry
Genetically regulated expression in late-onset Alzheimer's disease implicates risk genes within known and novel loci
Chen, H., et al.
2021,
Translational Psychiatry
Association of low-frequency and rare coding variants with information processing speed
Bressler, J., et al.
2021,
Nature Communications
A deep learning framework identifies dimensional representations of Alzheimer's Disease from brain structure
Yang, Z., et al.
2021,
American Journal of Human Genetics
Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics
He, Z., et al.
2021,
Nature Aging
Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease
Fang, J., et al.
2021,
Alzheimer's Research & Therapy
Serum zinc levels and in vivo beta-amyloid deposition in the human brain
Kim, JW., et al.
2021,
Translational Psychiatry
A missense variant in SHARPIN mediates Alzheimer's disease-specific brain damages
Park, JY., et al.
2021,
Alzheimer's Research & Therapy
Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer's disease
Park, YH., et al.
2021,
IEEE transactions on bio-medical engineering
Improved Prediction of Cognitive Outcomes via Globally Aligned Imaging Biomarker Enrichments Over Progressions
Lu, L., et al.
2021,
European journal of human genetics: EJHG
Exploiting family history in aggregation unit-based genetic association tests
Wang, Y., et al.
2021,
Cells
KYNA/Ahr Signaling Suppresses Neural Stem Cell Plasticity and Neurogenesis in Adult Zebrafish Model of Alzheimer's Disease
Siddiqui, T., et al.
2021,
Alzheimer's Research & Therapy
BMI1 is associated with CS8F amyloid-β and rates of cognitive decline in Alzheimer's disease
Kim, JP., et al.
2021,
JAMA network open
Association of Regional White Matter Hyperintensities With Longitudinal Alzheimer-Like Pattern of Neurodegeneration in Older Adults
Rizvi, B., et al.
2021,
Molecular Psychiatry
Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease
Panitch, R., et al.
2021,
Molecular Psychiatry
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease
DeMichele-Sweet, MAA., et al.
2021,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants
Damotte, V., et al.
2021,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Dementia in Africa: Current evidence, knowledge gaps, and future directions
Akinyemi, RO., et al.
2021,
Nature Neuroscience
Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders
Yang, C., et al.
2021,
Annals of Neurology
Polygenic Risk Score for Alzheimer's Disease in Caribbean Hispanics
Sariya, S., et al.
2021,
PLoS genetics
Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences
Zhan, L., et al.
2021,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Midlife vascular risk factors and risk of incident dementia: Longitudinal cohort and Mendelian randomization analyses in the UK Biobank
Malik, R., et al.
2021,
Translational Neurodegeneration
Predictability of polygenic risk score for progression to dementia and its interaction with APOE ε4 in mild cognitive impairment
Pyun, J., et al.
2021,
Neurobiology of Aging
Linkage of Alzheimer disease families with Puerto Rican ancestry identifies a chromosome 9 locus
Rajabli, F., et al.
2021,
Translational Psychiatry
Heterogeneous effects of genetic risk for Alzheimer's disease on the phenome
Wu, HM., et al.
2021,
Alzheimer's Research & Therapy
Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer's disease in Caribbean Hispanics
Horimoto, ARVR., et al.
2021,
Medical Image Analysis
A structural enriched functional network: An application to predict brain cognitive performance
Kim, M., et al.
2021,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds
Griswold, AJ., et al.
2021,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease
Zhang, X., et al.
2021,
Nature Communications
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
de Rojas, I., et al.
2021,
Journal of Genetic Counseling
Genetic counseling for early onset and familial dementia: Patient perspectives on exome sequencing
Rolf, B., et al.
2021,
Neurobiology of Disease
Deconstructing the epigenomic architecture of human neurodegeneration
De Jager, PL.
2021,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
The chronic neuropsychiatric sequelae of COVID-19: The need for a prospective study of viral impact on brain functioning
de Erausquin, GA., et al.
2021,
Stroke
Autonomic Imbalance and Risk of Dementia and Stroke: The Framingham Study
Weinstein, G., et al.
2021,
The European Journal of Neuroscience
Lifelong chronic psychosocial stress induces a proteomic signature of Alzheimer's disease in wildtype mice
Lyons, CE., et al.
2021,
Nature Communications
Identification of putative causal loci in whole-genome sequencing data via knockoff statistics
He, Z., et al.
2021,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Social network characteristics moderate associations between cortical thickness and cognitive functioning in older adults
Sharifian, N., et al.
2021,
Neurobiology of Aging
Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population
Marca-Ysabel, MV., et al.
2021,
Acta Neuropathologica
Proteomic identification of select protein variants of the SNARE interactome associated with cognitive reserve in a large community sample
Ramos-Miguel, A., et al.
2021,
Translational Psychiatry
Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue
Patel, D., et al.
2021,
Acta Neuropathologica Communications
Sex-specific DNA methylation differences in Alzheimer's disease pathology
Zhang, L., et al.
2021,
Journal of Neuropathology and Experimental Neurology
Asymmetry of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer Disease
An exploration of genetic association tests for disease risk and age at onset
Martin, ER., et al.
2021,
Stem Cell Research
Derivation of stem cell line UMi028-A-2 containing a CRISPR/Cas9 induced Alzheimer's disease risk variant p.S1038C in the TTC3 gene
Laverde-Paz, MJ., et al.
2021,
Acta Neuropathologica
Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer's disease in the European American population
Kirola, L., et al.
2021,
Neurology
Amyloid PET Imaging in Self-Identified Non-Hispanic Black Participants of the Anti-Amyloid in Asymptomatic Alzheimer's Disease (A4) Study
Deters, KD., et al.
2021,
Genes
Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants
Patel, D., et al.
2021,
Nature Communications
Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes
Novikova, G., et al.
2021,
Alzheimer's Research & Therapy
Genome-wide epistasis analysis for Alzheimer's disease and implications for genetic risk prediction
Wang, H., et al.
2021,
American Journal of Human Genetics
Genetic control of the human brain proteome
Robins, C., et al.
2021,
Molecular Psychiatry
Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer's disease
Mahoney, ER., et al.
2021,
Neurobiology of Aging
Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-ε4 carriers
Fulton-Howard, B., et al.
2021,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL)
Granot-Hershkovitz, E., et al.
2021,
Nature Genetics
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
Chia, R., et al.
2021,
Translational Psychiatry
Long runs of homozygosity are associated with Alzheimer's disease
Moreno-Grau, S., et al.
2021,
Neuron
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis
Dewan, R., et al.
2021,
Acta Neuropathologica
In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics
Xu, H., et al.
2021,
Nature Genetics
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis
Wingo, AP., et al.
2021,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Non-coding variants in MYH11, FZD3, and SORCS3 are associated with dementia in women
Blue, EE., et al.
2021,
Neuron
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease
Wang, M., et al.
2021,
Current Neurology and Neuroscience Reports
Early-Onset Alzheimer's Disease: What Is Missing in Research?
Ayodele, T., et al.
2021,
Translational Psychiatry
A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies
Patrick, E., et al.
2021,
Genome Biology
The variant call format provides efficient and robust storage of GWAS summary statistics
Lyon, MS., et al.
2021,
JAMA neurology
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis
Kunkle, BW., et al.
2021,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Education differentially contributes to cognitive reserve across racial/ethnic groups
Avila, JF., et al.
2021,
Molecular Psychiatry
Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging
Yan, Q., et al.
2021,
Journal of the American Geriatrics Society
A Systematic Review of Delirium Biomarkers and Their Alignment with the NIA-AA Research Framework
Wang, S., et al.
2021,
Science Advances
Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets
Neff, RA., et al.
2021,
Annals of Neurology
Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome
Andrews, SJ., et al.
2021,
PLoS genetics
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome
Baird, DA., et al.
2021,
Frontiers in Neuroscience
Predicting Brain Amyloid Using Multivariate Morphometry Statistics, Sparse Coding, and Correntropy: Validation in 1,101 Individuals From the ADNI and OASIS Databases
Wu, J., et al.
2021,
Methods in Molecular Biology (Clifton, N.J.)
Using INFERNO to Infer the Molecular Mechanisms Underlying Noncoding Genetic Associations
Amlie-Wolf, A., et al.
2021,
Journal of Alzheimer's disease: JAD
Lower Levels of Education Are Associated with Cognitive Impairment in the Old Order Amish
Ramos, J., et al.
2021,
Alzheimer's & Dementia (Amsterdam, Netherlands)
Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease
Xue, D., et al.
2020
2020,
BMC bioinformatics
Deep learning detection of informative features in tau PET for Alzheimer's disease classification
Jo, T., et al.
2020,
Science Translational Medicine
Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis
Lananna, BV., et al.
2020,
BMC medical informatics and decision making
Cognitive biomarker prioritization in Alzheimer's Disease using brain morphometric data
Peng, B., et al.
2020,
European journal of human genetics: EJHG
A quantitative trait rare variant nonparametric linkage method with application to age-at-onset of Alzheimer's disease
Zhao, L., et al.
2020,
NeuroImage
A comparison of Freesurfer and multi-atlas MUSE for brain anatomy segmentation: Findings about size and age bias, and inter-scanner stability in multi-site aging studies
Srinivasan, D., et al.
2020,
Trends in Neurosciences
Microglial Phagocytosis: A Disease-Associated Process Emerging from Alzheimer's Disease Genetics
Podleśny-Drabiniok, A., et al.
2020,
Acta Neuropathologica Communications
Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease
Ibanez, L., et al.
2020,
IEEE transactions on medical imaging
Associating Multi-Modal Brain Imaging Phenotypes and Genetic Risk Factors via a Dirty Multi-Task Learning Method
Du, L., et al.
2020,
Molecular Psychiatry
Genetic data and cognitively defined late-onset Alzheimer's disease subgroups
Mukherjee, S., et al.
2020,
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Parental History of Dementia Is Associated with Increased Small Vessel Cerebrovascular Disease
Stamm, BC., et al.
2020,
NeuroImage
Longitudinal ComBat: A method for harmonizing longitudinal multi-scanner imaging data
Beer, JC., et al.
2020,
JAMA neurology
Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease
Raghavan, NS., et al.
2020,
JAMA network open
Association of Uncommon, Noncoding Variants in the APOE Region With Risk of Alzheimer Disease in Adults of European Ancestry
Blue, EE., et al.
2020,
Neurobiology of Aging
LRP10 variants in progressive supranuclear palsy
Vergouw, LJM., et al.
2020,
Acta Neuropathologica
TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis
Cignarella, F., et al.
2020,
Nature
Negative feedback control of neuronal activity by microglia
Badimon, A., et al.
2020,
Nature Communications
Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture
Zhang, Q., et al.
2020,
Nature Communications
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults
Hofer, E., et al.
2020,
Neurology
Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study
Peloso, GM., et al.
2020,
EMBO molecular medicine
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation
Ewers, M., et al.
2020,
Alzheimer's Research & Therapy
Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease
Lancour, D., et al.
2020,
Journal of Neuropathology and Experimental Neurology
Insoluble Tau From Human FTDP-17 Cases Exhibit Unique Transmission Properties In Vivo
Weitzman, SA., et al.
2020,
Cell Reports
Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia
Ouellette, AR., et al.
2020,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Circulating ethanolamine plasmalogen indices in Alzheimer's disease: Relation to diagnosis, cognition, and CSF tau
Kling, MA., et al.
2020,
Genome Biology
PSCAN: Spatial scan tests guided by protein structures improve complex disease gene discovery and signal variant detection
Tang, Z., et al.
2020,
Journal of the American Geriatrics Society
Measurement and Structure of Cognition in the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia
Gross, AL., et al.
2020,
Journal of the American Geriatrics Society
Introduction to LASI-DAD: The Longitudinal Aging Study in India-Diagnostic Assessment of Dementia
Lee, J.
2020,
Journal of the American Geriatrics Society
Design and Methodology of the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (LASI-DAD)
Lee, J., et al.
2020,
Journal of the American Geriatrics Society
Association Between Episodic Memory and Genetic Risk Factors for Alzheimer's Disease in South Asians from the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (LASI-DAD)
Smith, JA., et al.
2020,
Neurology. Genetics
Synonymous variants associated with Alzheimer disease in multiplex families
Tang, M., et al.
2020,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways
Sherva, R., et al.
2020,
Neurobiology of Disease
Genetic architecture of common non-Alzheimer's disease dementias
Guerreiro, R., et al.
2020,
PLoS genetics
On the cross-population generalizability of gene expression prediction models
Keys, KL., et al.
2020,
Brain: A Journal of Neurology
Genetic variants and functional pathways associated with resilience to Alzheimer's disease
Dumitrescu, L., et al.
2020,
Molecular Psychiatry
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation
Bis, JC., et al.
2020,
Journal of the American Geriatrics Society
Hypertension and Cognitive Health Among Older Adults in India
Farron, MR., et al.
2020,
Journal of the American Geriatrics Society
New Insights and Knowledge on Cognition and Dementia from Population-Based Cohort of Older Adults in India
Kenny, RA.
2020,
Journal of the American Geriatrics Society
Online Clinical Consensus Diagnosis of Dementia: Development and Validation
Lee, J., et al.
2020,
Journal of the American Geriatrics Society
Sex Differences in Cognitive Health Among Older Adults in India
Angrisani, M., et al.
2020,
Brain: A Journal of Neurology
Sex-dependent autosomal effects on clinical progression of Alzheimer's disease
Fan, CC., et al.
2020,
JAMA neurology
Association of Klotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who Carry APOE4
Belloy, ME., et al.
2020,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
MAPT haplotype-stratified GWAS reveals differential association for AD risk variants
Strickland, SL., et al.
2020,
Stroke
Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities
Armstrong, NJ., et al.
2020,
Journal of the American Geriatrics Society
Interplay between Socioeconomic Markers and Polygenic Predisposition on Timing of Dementia Diagnosis
Ajnakina, O., et al.
2020,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community
Knopman, D., et al.
2020,
Bioinformatics (Oxford, England)
SparkINFERNO: a scalable high-throughput pipeline for inferring molecular mechanisms of non-coding genetic variants
Kuksa, PP., et al.
2020,
An International Journal on Information Fusion
Autosomal Dominantly Inherited Alzheimer Disease: Analysis of genetic subgroups by Machine Learning
Castillo-Barnes, D., et al.
2020,
Neurobiology of Disease
Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2
Hsu, S., et al.
2020,
NAR genomics and bioinformatics
HIPPIE2: a method for fine-scale identification of physically interacting chromatin regions
Kuksa, PP., et al.
2020,
Alzheimer Disease and Associated Disorders
The Utility of the National Alzheimer's Coordinating Center's Database for the Rapid Assessment of Evolving Neuropathologic Conditions
Mock, C., et al.
2020,
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Time for Well-Powered Controlled Prospective Studies to Test a Causal Role for Herpes Viruses in Alzheimer's Disease Using Antiherpetic Drugs
Goldschmidt-Clermont, PJ., et al.
2020,
Neurobiology of Aging
Failure to detect synergy between variants in transferrin and hemochromatosis and Alzheimer's disease in large cohort
Vance, E., et al.
2020,
Neurology
Long-term exposure to air pollution and trajectories of cognitive decline among older adults
Kulick, ER., et al.
2020,
JAMA psychiatry
Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition
Writing Committee for the ENIGMA-CNV Working Group, ., et al.
2020,
The Lancet. Neurology
Interpretation of risk loci from genome-wide association studies of Alzheimer's disease
Andrews, SJ., et al.
2020,
Neurology. Genetics
Use of local genetic ancestry to assess TOMM40-523' and risk for Alzheimer disease
Bussies, PL., et al.
2020,
Science (New York, N.Y.)
The genetic architecture of the human cerebral cortex
Grasby, KL., et al.
2020,
Molecular Psychiatry
A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease
Hartl, D., et al.
2020,
Scientific Reports
Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype
Friedberg, JS., et al.
2020,
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Epigenetic Age Acceleration and Cognitive Function in African American Adults in Midlife: The Atherosclerosis Risk in Communities Study
Bressler, J., et al.
2020,
Science Translational Medicine
APOE genotype regulates pathology and disease progression in synucleinopathy
Davis, AA., et al.
2020,
Nature Communications
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study
Reiman, EM., et al.
2020,
Annals of Clinical and Translational Neurology
Circulating ceramide ratios and risk of vascular brain aging and dementia
McGrath, ER., et al.
2020,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Intact global cognitive and olfactory ability predicts lack of transition to dementia
Devanand, DP., et al.
2020,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Association between alcohol consumption and Alzheimer's disease: A Mendelian randomization study
Andrews, SJ., et al.
2020,
PLoS genetics
Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs
Ramdhani, S., et al.
2020,
Current Opinion in Immunology
Innate sensing of mechanical properties of brain tissue by microglia
Ayata, P.
2020,
Neurology
Association of CD14 with incident dementia and markers of brain aging and injury
Pase, MP., et al.
2020,
Nature Communications
Transmission of tauopathy strains is independent of their isoform composition
He, Z., et al.
2020,
The Lancet. Neurology
Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies
Ding, J., et al.
2020,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer
Pathak, GA., et al.
2020,
Acta Neuropathologica
The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion
Li, Z., et al.
2020,
Neuropsychology
Linking depressive symptoms and cognitive functioning: The mediating role of leisure activity
Sharifian, N., et al.
2020,
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Packaging Biocomputing Software to Maximize Distribution and Reuse
Bush, WS., et al.
2020,
Alzheimer's & Dementia (New York, N. Y.)
Development and validation of language and visuospatial composite scores in ADNI
Choi, S., et al.
2020,
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Hadoop and PySpark for reproducibility and scalability of genomic sequencing studies
Wheeler, NR., et al.
2020,
Journal of Alzheimer's disease: JAD
Circulating Vitamin D Levels and Alzheimer's Disease: A Mendelian Randomization Study in the IGAP and UK Biobank
Wang, L., et al.
2020,
Alzheimer's & Dementia (New York, N. Y.)
Differences in plasma metabolites related to Alzheimer's disease, APOE ε4 status, and ethnicity
Vardarajan, B., et al.
2020,
Journal of Alzheimer's disease: JAD
Immune and Inflammatory Pathways Implicated by Whole Blood Transcriptomic Analysis in a Diverse Ancestry Alzheimer's Disease Cohort
Griswold, AJ., et al.
2020,
Journal of Alzheimer's disease: JAD
Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD Through Multiple Phenotypes
Olive, C., et al.
2020,
Journal of Alzheimer's disease: JAD
A Coordinated Approach by Public Domain Bioinformatics Resources to Aid the Fight Against Alzheimer's Disease Through Expert Curation of Key Protein Targets
Breuza, L., et al.
2020,
Computational and Structural Biotechnology Journal
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA)
González, HM., et al.
2019,
PLoS genetics
Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations
Kowalski, MH., et al.
2019,
Alzheimer's & Dementia (Amsterdam, Netherlands)
Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration
Smith, EE., et al.
2019,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Local ancestry at APOE modifies Alzheimer's disease risk in Caribbean Hispanics
Blue, EE., et al.
2019,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Secular trends in cognitive trajectories of diverse older adults
Vonk, JMJ., et al.
2019,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Current and past leisure time physical activity in relation to risk of Alzheimer's disease in older adults
Ogino, E., et al.
2019,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Sex/gender differences in cognitive trajectories vary as a function of race/ethnicity
Avila, JF., et al.
2019,
Brain: A Journal of Neurology
Genetic and epigenetic study of an Alzheimer's disease family with monozygotic triplets
Zhang, M., et al.
2019,
Nature Neuroscience
An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations
Dube, U., et al.
2019,
Nature Genetics
Genetic architecture of subcortical brain structures in 38,851 individuals
Satizabal, CL., et al.
2019,
Neuroscience Letters
Promoter DNA hypermethylation - Implications for Alzheimer's disease
Liu, Y., et al.
2019,
American Journal of Human Genetics
A Rare Variant Nonparametric Linkage Method for Nuclear and Extended Pedigrees with Application to Late-Onset Alzheimer Disease via WGS Data
Zhao, L., et al.
2019,
Circulation Research
Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals
Georgakis, MK., et al.
2019,
Nature Communications
Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease
Huan, T., et al.
2019,
Human Molecular Genetics
RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways
Gardner, OK., et al.
2019,
Brain: A Journal of Neurology
Sex differences in the genetic predictors of Alzheimer's pathology
Dumitrescu, L., et al.
2019,
JAMA neurology
Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype
Ma, Y., et al.
2019,
Liver International: Official Journal of the International Association for the Study of the Liver
Non-alcoholic fatty liver disease, liver fibrosis score and cognitive function in middle-aged adults: The Framingham Study
Weinstein, G., et al.
2019,
Nature Genetics
Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Kunkle, BW., et al.
2019,
Science Translational Medicine
Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease
Ewers, M., et al.
2019,
Journal of Clinical Medicine
APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer's Disease Risk in a Multiracial Sample
Choi, KY., et al.
2019,
Science Translational Medicine
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk
Deming, Y., et al.
2019,
Alzheimer's Research & Therapy
A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain
Del-Aguila, JL., et al.
2019,
American Journal of Human Genetics
TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits
Nagpal, S., et al.
2019,
The American Journal of Clinical Nutrition
Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals
Mandaviya, PR., et al.
2019,
JAMA neurology
Association of Variants in PINX1 and TREM2 With Late-Onset Alzheimer Disease
Tosto, G., et al.
2019,
Aging Cell
CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease
Ma, Y., et al.
2019,
Cell Reports
Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer's Disease
Canchi, S., et al.
2019,
Genomics
Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project
Naj, AC., et al.
2019,
Bioinformatics (Oxford, England)
VCPA: genomic variant calling pipeline and data management tool for Alzheimer's Disease Sequencing Project
Leung, YY., et al.
2019,
Nature
Genetic analyses of diverse populations improves discovery for complex traits
Wojcik, GL., et al.
2019,
Genome Biology
Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight
Ebbert, MTW., et al.
2019,
Nature Communications
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Davies, G., et al.
2019,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Brain arterial dilatation and the risk of Alzheimer's disease
Gutierrez, J., et al.
2019,
Neurology
A prospective study of serum metabolites and risk of ischemic stroke
Sun, D., et al.
2019,
JAMA network open
Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study
Spartano, NL., et al.
2019,
Brain: A Journal of Neurology
Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects
Mishra, A., et al.
2019,
Annals of Clinical and Translational Neurology
Alternative splicing in a presenilin 2 variant associated with Alzheimer disease
Braggin, JE., et al.
2019,
Nature Genetics
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Bentley, AR., et al.
2019,
JAMA network open
Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry
Patel, D., et al.
2019,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease
Zhang, X., et al.
2019,
Nature Genetics
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Kunkle, BW., et al.
2019,
Blood
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology
de Vries, PS., et al.
2019,
Neurology
Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study
Larsson, SC., et al.
2019,
Neurology
The emerging genetic landscape of cerebral white matter hyperintensities
Fornage, M.
2019,
Acta Neuropathologica
Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease
Broce, IJ., et al.
2019,
Briefings in Bioinformatics
Association score testing for rare variants and binary traits in family data with shared controls
Saad, M.
2019,
Journal of Diabetes Research
Self-Reported Physical Activity and Relations to Growth and Neurotrophic Factors in Diabetes Mellitus: The Framingham Offspring Study
Spartano, NL., et al.
2019,
Alzheimer's & Dementia (New York, N. Y.)
Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study
Spartano, NL., et al.
2019,
Communications Biology
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes
van der Lee, SJ., et al.
2019,
PloS One
Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts
Weinstein, G., et al.
2019,
Journal of Alzheimer's disease: JAD
Education Moderates the Relation Between APOE ɛ4 and Memory in Nondemented Non-Hispanic Black Older Adults
Vonk, JMJ., et al.
2019,
PloS One
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease
Baker, E., et al.
2019,
Frontiers in Genetics
Rare Variants Imputation in Admixed Populations: Comparison Across Reference Panels and Bioinformatics Tools
Sariya, S., et al.
2019,
Frontiers in Genetics
The Puerto Rico Alzheimer Disease Initiative (PRADI): A Multisource Ascertainment Approach
Feliciano-Astacio, BE., et al.
2019,
Journal of Alzheimer's disease: JAD
Inferring the Molecular Mechanisms of Noncoding Alzheimer's Disease-Associated Genetic Variants
Amlie-Wolf, A., et al.
2019,
PloS One
The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)
Wolters, FJ., et al.
2019,
Genome Research
Comparison and assessment of family- and population-based genotype imputation methods in large pedigrees
Ullah, E., et al.
2018
2018,
Translational Psychiatry
Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP
Jiang, S., et al.
2018,
PLoS genetics
Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations
Rajabli, F., et al.
2018,
Neurobiology of Aging
Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease
Gusareva, ES., et al.
2018,
Acta Neuropathologica
Sex-specific genetic predictors of Alzheimer's disease biomarkers
Deming, Y., et al.
2018,
Neurology. Genetics
Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease
Beecham, GW., et al.
2018,
Nucleic Acids Research
INFERNO: inferring the molecular mechanisms of noncoding genetic variants
Amlie-Wolf, A., et al.
2018,
Stroke
Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults
Raman, MR., et al.
2018,
Genetic Epidemiology
Analysis of pedigree data in populations with multiple ancestries: Strategies for dealing with admixture in Caribbean Hispanic families from the ADSP
Nafikov, RA., et al.
2018,
Bioinformatics (Oxford, England)
Functional annotation of genomic variants in studies of late-onset Alzheimer's disease
Butkiewicz, M., et al.
2018,
Stroke
Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging
Jian, X., et al.
2018,
Bioinformatics (Oxford, England)
Integrative DNA copy number detection and genotyping from sequencing and array-based platforms
Zhou, Z., et al.
2018,
Genes, Brain, and Behavior
Variants regulating ZBTB4 are associated with age-at-onset of Alzheimer's disease
Blue, EE., et al.
2018,
Annals of Clinical and Translational Neurology
Whole-exome sequencing in 20,197 persons for rare variants in Alzheimer's disease
Raghavan, NS., et al.
2018,
Preventive Medicine
Vascular risk factor burden and new-onset depression in the community
Adams, S., et al.
2018,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts
Tynkkynen, J., et al.
2018,
Translational Psychiatry
GWAS on family history of Alzheimer's disease
Marioni, RE., et al.
2018,
Bioinformatics (Oxford, England)
GIGI-Quick: a fast approach to impute missing genotypes in genome-wide association family data
Kunji, K., et al.
2018,
Annals of Clinical and Translational Neurology
Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease
Vardarajan, BN., et al.
2018,
PloS One
The APOE ε4 allele is associated with a reduction in FEV1/FVC in women: A cross-sectional analysis of the Long Life Family Study
Kulminski, AM., et al.
2018,
Journal of Alzheimer's disease: JAD
Genetic Interaction with Plasma Lipids on Alzheimer's Disease in the Framingham Heart Study
Peloso, GM., et al.
2018,
Dementia and Geriatric Cognitive Disorders
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project
Blue, EE., et al.
2017
2017,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Alzheimer's Disease Sequencing Project discovery and replication criteria for cases and controls: Data from a community-based prospective cohort study with autopsy follow-up
Crane, PK., et al.
2017,
PLoS genetics
Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease
Fernández, MV., et al.
2017,
Molecular Neurodegeneration
Whole blood gene expression and white matter Hyperintensities
Lin, H., et al.
2017,
Bioinformatics (Oxford, England)
Introducing COCOS: codon consequence scanner for annotating reading frame changes induced by stop-lost and frame shift variants
Butkiewicz, M., et al.
2017,
Journal of Alzheimer's disease: JAD
Methionine Sulfoxide Reductase-B3 (MsrB3) Protein Associates with Synaptic Vesicles and its Expression Changes in the Hippocampi of Alzheimer's Disease Patients
Adams, SL., et al.
2016
2016,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease
Kunkle, BW., et al.
2015
2015,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease