Exploring nightly variability and clinical influences on sleep measures: insights from a digital brain health platform.
Ding, H., et al.
2025,  
Sleep medicine
Exploring nightly variability and clinical influences on sleep measures: insights from a digital brain health platform.
Ding, H., et al.
2025,  
Sleep medicine
Exploring nightly variability and clinical influences on sleep measures: insights from a digital brain health platform.
Ding, H., et al.
2025,  
Sleep medicine
Exploring nightly variability and clinical influences on sleep measures: insights from a digital brain health platform.
Ding, H., et al.
2025,  
Sleep medicine
Exploring nightly variability and clinical influences on sleep measures: insights from a digital brain health platform.
Ding, H., et al.
2025,  
Sleep medicine
Exploring nightly variability and clinical influences on sleep measures: insights from a digital brain health platform.
Ding, H., et al.
2025,  
Alzheimer disease and associated disorders
Asian Cohort for Alzheimer Disease (ACAD) Pilot Study: Vietnamese Americans.
Peavy, GM., et al.
2025,  
Alzheimer disease and associated disorders
Visuospatial and Verbal Memory Differences in Amish Individuals With Alzheimer Disease and Related Dementias.
Prough, MB., et al.
2025,  
Alzheimer disease and associated disorders
Clinical Profiles of Arteriolosclerosis and Alzheimer Disease at Mild Cognitive Impairment and Mild Dementia in a National Neuropathology Cohort.
Yang, D.
2025,  
Alzheimer disease and associated disorders
A Novel Method for Establishing Functional Change in Older Adults With Cognitive Impairment.
González, DA., et al.
2025,  
Journal of the American Society of Nephrology : JASN
Uremic Toxins, CKD, and Cognitive Dysfunction.
Andrews, TD., et al.
2025,  
Nature human behaviour
Charting brain functional development from birth to 6 years of age.
Yin, W., et al.
2025,  
Annals of neurology
The Use of Antihypertensive Medication and In Vivo Alzheimer's Disease Pathology.
Keum, M., et al.
2025,  
Molecular psychiatry
X-chromosome-wide association study for Alzheimer's disease.
Le Borgne, J., et al.
2025,  
Glia
Contributions of Genetic Variation in Astrocytes to Cell and Molecular Mechanisms of Risk and Resilience to Late-Onset Alzheimer's Disease.
Lee, H., et al.
2025,  
The journals of gerontology. Series B, Psychological sciences and social sciences
Understanding the Stress Process Among Mexican American Adults Aged 50 and Older in the United States.
Muñoz, E., et al.
2025,  
Acta neuropathologica communications
Age-dependent interactions of APOE isoform 4 and Alzheimer's disease neuropathology: findings from the NACC.
Hayes, CA., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Sleep macro-architecture, nocturnal hypoxemia, and Alzheimer's disease-related MRI patterns among diverse older adults.
Liu, DX., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Racial ethnic variations in the cardiometabolic determinants and blood pressure of white matter hyperintensities among females-The HABS-HD Study.
Hayes, CA., et al.
2025,  
medRxiv : the preprint server for health sciences
Identification and Validation of New Molecular Subtypes within the Early and Late Mild Cognitive Impairment Stages of Alzheimer's Disease.
Li, B., et al.
2025,  
The Clinical neuropsychologist
Health insurance coverage moderates the relationship between metabolic syndrome and baseline memory outcomes in Latino older adults.
Breton, J., et al.
2025,  
medRxiv : the preprint server for health sciences
Mediating effect of pro-inflammatory cytokines in the association between depression, anxiety, and cardiometabolic disorders in an ethnically diverse community-dwelling middle-aged and older US population.
Hallab, A.
2025,  
medRxiv : the preprint server for health sciences
Mediating role of Interleukin-6 in the predictive association of diabetes with Hippocampus atrophy, Amyloid, Tau, and Neurofilament pathology at pre-clinical stages of diabetes-related cognitive impairment.
Hallab, A.
2025,  
Nature genetics
CHOIR improves significance-based detection of cell types and states from single-cell data.
Sant, C., et al.
2025,  
Neuron
Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures across the Alzheimer disease continuum.
Ali, M., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Ubiquitin-proteasome system in the different stages of dominantly inherited Alzheimer's disease.
Liu, H., et al.
2025,  
Molecular neurodegeneration
Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication.
Zhao, X., et al.
2025,  
Research square
Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American Populations.
Acosta-Uribe, J., et al.
2025,  
medRxiv : the preprint server for health sciences
Interpretable MRI-Based Deep Learning for Alzheimer's Risk and Progression.
Lu, B., et al.
2025,  
BioData mining
Network-based analyses of multiomics data in biomedicine.
Kumar, R., et al.
2025,  
medRxiv : the preprint server for health sciences
Bayesian inference of genetic pleiotropy identifies drug targets and repurposable medicines for human complex diseases.
Lorincz-Comi, N.
2025,  
Proceedings of the National Academy of Sciences of the United States of America
Inhibiting 15-PGDH blocks blood-brain barrier deterioration and protects mice from Alzheimer's disease and traumatic brain injury.
Koh, Y., et al.
2025,  
medRxiv : the preprint server for health sciences
D3MI: an efficient and powerful federated imputation method for bias reduction in the analysis of distributed incomplete data by accounting for within-site correlation and between-site heterogeneity.
Lian, Y., et al.
2025,  
International journal of molecular sciences
Genetic, Transcriptomic, and Epigenomic Insights into Sjögren's Disease: An Integrative Network Investigation and Immune Diseases Comparison.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference.
Frost, B., et al.
2025,  
Journal of neurology, neurosurgery, and psychiatry
Telomere length, in vivo Alzheimer's disease pathologies and cognitive decline in older adults.
Jung, JH., et al.
2025,  
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
The Effect of Cholinesterase Inhibitors on Neurodegeneration in Individuals with Amnestic Mild Cognitive Impairment.
Byeon, G., et al.
2025,  
Communications biology
Leveraging multivariate information for community detection in functional brain networks.
Puxeddu, MG., et al.
2025,  
Nature medicine
A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer's disease.
Oh, HS., et al.
2025,  
The journal of prevention of Alzheimer's disease
Association of dietary fatty acids with longitudinal change in plasma-based biomarkers of Alzheimer's disease.
Hoost, SS., et al.
2025,  
medRxiv : the preprint server for health sciences
Heritability of Alzheimer-related plasma biomarkers in the Amish population.
Wang, P., et al.
2025,  
Nature communications
An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration.
Leventhal, MJ., et al.
2025,  
Movement disorders : official journal of the Movement Disorder Society
Copy Number Variation and Haplotype Analysis of 17q21.31 Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells.
Wang, H., et al.
2025,  
medRxiv : the preprint server for health sciences
Multi-population Genome-Wide Association Study Identifies Multiple Novel Loci associated with Asymptomatic Intracranial Large Artery Stenosis.
Liu, M., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Sequencing the gaps: dark genomic regions persist in CHM13 despite long-read advances.
Wadsworth, ME., et al.
2025,  
Journal of Alzheimer's disease : JAD
Association of Alzheimer's disease biomarkers with low premorbid intellectual functioning in a multi-ethnic community-dwelling cohort: A cross-sectional study of HABS-HD.
Abdullah, L., et al.
2025,  
Proceedings. IEEE International Symposium on Biomedical Imaging
AUTOENCODER FOR 4-DIMENSIONAL FIBER ORIENTATION DISTRIBUTIONS FROM DIFFUSION MRI.
Huang, S., et al.
2025,  
medRxiv : the preprint server for health sciences
Chronic emotional stress and mediating role of Interleukine-6 in the association with cardiometabolic disorders in a multiethnic middle-aged and older US-population.
Hallab, A.
2025,  
medRxiv : the preprint server for health sciences
Mediating effect of pro-inflammatory cytokines in the association between depression, anxiety, and cardiometabolic disorders in an ethnically diverse middle-aged and older population.
Hallab, A.
2025,  
Cell
Turnover atlas of proteome and phosphoproteome across mouse tissues and brain regions.
Li, W., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Somatic and Stem Cell Bank to study the contribution of African ancestry to dementia: African iPSC Initiative.
Maina, MB., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genome-wide association analysis identifies APOE as a mitophagy modifier in Lewy body disease.
Hou, X., et al.
2025,  
Genome research
Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease.
Jensen, TD., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Addressing overfitting bias due to sample overlap in polygenic risk scoring.
Jeong, S., et al.
2025,  
Human brain mapping
MRI Distance Measures as a Predictor of Subsequent Clinical Status During the Preclinical Phase of Alzheimer's Disease and Related Disorders.
Zhang, X., et al.
2025,  
PLoS genetics
Enhancing nonlinear transcriptome- and proteome-wide association studies via trait imputation with applications to Alzheimer's disease.
He, R., et al.
2025,  
Nature genetics
Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes.
Henry, A., et al.
2025,  
Scientific reports
Association of the digital clock drawing test with amyloid and tau PET biomarkers in low age risk adults.
Ding, H., et al.
2025,  
Nature communications
A genetically informed brain atlas for enhancing brain imaging genomics.
Bao, J., et al.
2025,  
BioData mining
Enhancing clinical outcome predictions through effective sample size evaluation in graph-based digital twin modeling.
Li, X., et al.
2025,  
ArXiv
Knowledge-Driven Feature Selection and Engineering for Genotype Data with Large Language Models.
Lee, J., et al.
2025,  
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Utilization of precision medicine digital twins for drug discovery in Alzheimer's disease.
Ren, Y., et al.
2025,  
Scientific reports
A pioneering artificial intelligence tool to predict treatment outcomes in ovarian cancer via diagnostic laparoscopy.
Ma, X., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
APOE and Alzheimer's disease and related dementias risk among 12,221 Hispanics/Latinos.
Barral, S., et al.
2025,  
medRxiv : the preprint server for health sciences
Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review.
Liu, S., et al.
2025,  
Alzheimer's research & therapy
Integrative network analysis reveals novel moderators of Aβ-Tau interaction in Alzheimer's disease.
Kitani, A.
2025,  
Acta neuropathologica
LATE-NC Stage 3: a diagnostic rubric to differentiate severe LATE-NC from FTLD-TDP.
Shahidehpour, RK., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Long sleep duration, cognitive performance, and the moderating role of depression: A cross-sectional analysis in the Framingham Heart Study.
Young, VM., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Elevated serum cortisol associated with early-detected increase of brain amyloid deposition in Alzheimer's disease imaging biomarkers among menopausal women: The Framingham Heart Study.
Salardini, A., et al.
2025,  
Neurology. Genetics
Whole Genome Variable Number Tandem Repeat Analysis in Alzheimer Disease.
Heath, A., et al.
2025,  
Nature genetics
Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing.
Humphrey, J., et al.
2025,  
medRxiv : the preprint server for health sciences
SingleBrain: A Meta-Analysis of Single-Nucleus eQTLs Linking Genetic Risk to Brain Disorders.
Jang, B., et al.
2025,  
bioRxiv : the preprint server for biology
Cytosine-to-uracil RNA editing is upregulated by pro-inflammatory stimulation of myeloid cells.
Seo, H., et al.
2025,  
Journal of the American Geriatrics Society
Design and methodology of the harmonized diagnostic assessment of dementia for the longitudinal aging study in India: Wave 2.
Khobragade, PY., et al.
2025,  
Neuropsychology
The association of multilingualism with diverse language families and cognition among adults with and without education in India.
Petrosyan, S., et al.
2025,  
Nature biotechnology
Analysis and benchmarking of small and large genomic variants across tandem repeats.
English, AC., et al.
2025,  
Nature genetics
Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk.
Choi, SH., et al.
2025,  
Journal of neurology, neurosurgery, and psychiatry
Genetics impact risk of Alzheimer's disease through mechanisms modulating structural brain morphology in late life.
Leveraging multimodal neuroimaging and GWAS for identifying modality-level causal pathways to Alzheimer's disease.
Tian, Y., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Distinct medical and substance use histories associate with cognitive decline in Alzheimer's disease.
Mansel, C., et al.
2025,  
Research square
Sex-specific Associations of Gene Expression with Alzheimer's Disease Neuropathology and Ante-mortem Cognitive Performance.
Dumitrescu, L., et al.
2025,  
PLoS genetics
Local genetic covariance analysis with lipid traits identifies novel loci for early-onset Alzheimer's Disease.
Ray, NR., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Generalizability of tau and amyloid plasma biomarkers in Alzheimer's disease cohorts of diverse genetic ancestries.
Griswold, AJ., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Chronic stress, social support, and Alzheimer's blood-based biomarkers in the HABS-HD study.
Lee, JK., et al.
2025,  
medRxiv : the preprint server for health sciences
Objective Sleep Quality in Diverse Older Adults: the Importance of Race and Ethnicity and Sex.
Cavaillès, C., et al.
2025,  
Neurobiology of disease
Alzheimer's disease risk ABCA7 p.A696S variant disturbs the microglial response to amyloid pathology in mice.
Ma, X., et al.
2025,  
bioRxiv : the preprint server for biology
Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer's disease.
Trushin, S., et al.
2025,  
Neuron
The night's watch: Exploring how sleep protects against neurodegeneration.
Parhizkar, S.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Neuronal ABCA7 deficiency aggravates mitochondrial dysfunction and neurodegeneration in Alzheimer's disease.
Wang, N., et al.
2025,  
bioRxiv : the preprint server for biology
Midkine Attenuates Aβ Fibril Assembly and Amyloid Plaque Formation.
Zaman, M., et al.
2025,  
Neuron
CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions.
Li, E., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Interactions between menopause and high-fat diet on cognition and pathology in a mouse model of Alzheimer's disease.
Abi-Ghanem, C., et al.
2025,  
NPJ Parkinson's disease
Longitudinal multi-omics in alpha-synuclein Drosophila model discriminates disease- from age-associated pathologies in Parkinson's disease.
Moore, J., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
The impact of arteriolosclerosis on cognitive impairment in decedents without severe dementia from the National Alzheimer's Coordinating Center.
Hayes, CA., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Amyloid PET predicts longitudinal functional and cognitive trajectories in a heterogeneous cohort.
Younes, K., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Plasma protein risk scores for mild cognitive impairment and Alzheimer's disease in the Framingham heart study.
Rehman, H., et al.
2025,  
Neural networks : the official journal of the International Neural Network Society
BPEN: Brain Posterior Evidential Network for trustworthy brain imaging analysis.
Ye, K., et al.
2025,  
BioData mining
High-dimensional mediation analysis reveals the mediating role of physical activity patterns in genetic pathways leading to AD-like brain atrophy.
Xu, H., et al.
2025,  
Communications biology
Longitudinal excitation-inhibition balance altered by sex and APOE-ε4.
Burns, AP., et al.
2025,  
medRxiv : the preprint server for health sciences
Leveraging functional annotations to map rare variants associated with Alzheimer's disease with gruyere.
Das, A., et al.
2025,  
medRxiv : the preprint server for health sciences
Vision Transformer Autoencoders for Unsupervised Representation Learning: Capturing Local and Non-Local Features in Brain Imaging to Reveal Genetic Associations.
Islam, SR., et al.
2025,  
Human genetics
Assessing the predicted impact of single amino acid substitutions in calmodulin for CAGI6 challenges.
Turina, P., et al.
2025,  
Human genetics
Assessing the predicted impact of single amino acid substitutions in MAPK proteins for CAGI6 challenges.
Turina, P., et al.
2025,  
Human genetics
Evaluation of enzyme activity predictions for variants of unknown significance in Arylsulfatase A.
Jain, S., et al.
2025,  
The Journal of clinical endocrinology and metabolism
Defining Continuous Glucose Monitor Time in Range in a Large, Community-Based Cohort Without Diabetes.
Spartano, NL., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Dynamic lifetime risk prediction of Alzheimer's disease with longitudinal cognitive assessment measurements.
Ding, H., et al.
2025,  
JMIR formative research
Digital Assessment of Cognitive Health in Outpatient Primary Care: Usability Study.
Doerr, AJ., et al.
2025,  
Bioinformatics (Oxford, England)
Rethinking GWAS: how lessons from genetic screens and artificial intelligence could reveal biological mechanisms.
Hazelett, DJ.
2025,  
Bioinformatics (Oxford, England)
Predicting explainable dementia types with LLM-aided feature engineering.
Kashyap, AM., et al.
2025,  
PLoS medicine
Efficacy and safety of passive immunotherapies targeting amyloid beta in Alzheimer's disease: A systematic review and meta-analysis.
Tonegawa-Kuji, R., et al.
2025,  
Genome medicine
Structural variants linked to Alzheimer's disease and other common age-related clinical and neuropathologic traits.
Vialle, RA., et al.
2025,  
Stroke
Socioeconomic Status and Stroke: A Review of the Latest Evidence on Inequalities and Their Drivers.
Pantoja-Ruiz, C., et al.
2025,  
medRxiv : the preprint server for health sciences
Genetic Regulation of the Metabolome Differs by Sex, Alzheimer's Disease Stage, and Plasma Biomarker Status.
Eissman, JM., et al.
2025,  
eNeuro
Detection of Mitotic Neuroblasts Provides Additional Evidence of Steady-State Neurogenesis in the Adult Small Intestinal Myenteric Plexus.
Gorecki, AM., et al.
2025,  
Journal of neurotrauma
Traumatic Brain Injury and Alzheimer's Disease Biomarkers: A Systematic Review of Findings from Amyloid and Tau Positron Emission Tomography.
Dybing, KM., et al.
2025,  
Journal of Alzheimer's disease : JAD
Daily fluid intake and brain amyloid deposition: A cohort study.
Kim, JW., et al.
2025,  
Research square
Large-scale Plasma Proteomic Profiling Unveils Novel Diagnostic Biomarkers and Pathways for Alzheimer's Disease.
Cruchaga, C., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Considerations in the clinical use of amyloid PET and CSF biomarkers for Alzheimer's disease.
Leuzy, A., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Preclinical Alzheimer's disease shows alterations in circulating neuronal-derived extracellular vesicle microRNAs in a multiethnic cohort.
Reho, P., et al.
2025,  
Journal of the American Geriatrics Society
Neighborhoods, Networks, and Neurodegeneration: A Call for Population-Level Policy and Advancing the Exposome.
Babulal, GM.
2025,  
Human brain mapping
Cross-Sectional Comparison of Structural MRI Markers of Impairment in a Diverse Cohort of Older Adults.
Wisch, JK., et al.
2025,  
Nature communications
Human and mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome.
Yarbro, JM., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Role of tau versus TDP-43 pathology on medial temporal lobe atrophy in aging and Alzheimer's disease.
Wisse, LEM., et al.
2025,  
bioRxiv : the preprint server for biology
CHOIR improves significance-based detection of cell types and states from single-cell data.
Sant, C., et al.
2025,  
Human brain mapping
Head Motion in Diffusion Magnetic Resonance Imaging: Quantification, Mitigation, and Structural Associations in Large, Cross-Sectional Datasets Across the Lifespan.
Schilling, KG., et al.
2025,  
Nature communications
Automated cytometric gating with human-level performance using bivariate segmentation.
Chen, J., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Functional insight into East Asian-specific genetic risk loci for Alzheimer's disease.
Cho, M., et al.
2025,  
bioRxiv : the preprint server for biology
Synthetic Diffusion Tensor Imaging Maps Generated by 2D and 3D Probabilistic Diffusion Models: Evaluation and Applications.
Chattopadhyay, T., et al.
2025,  
Cancers
Advancing Pancreatic Cancer Prediction with a Next Visit Token Prediction Head on Top of Med-BERT.
He, J., et al.
2025,  
Journal of diabetes science and technology
Expert Clinical Interpretation of Continuous Glucose Monitor Reports From Individuals Without Diabetes.
Spartano, NL., et al.
2025,  
Bioinformatics (Oxford, England)
ESCARGOT: an AI agent leveraging large language models, dynamic graph of thoughts, and biomedical knowledge graphs for enhanced reasoning.
Matsumoto, N., et al.
2025,  
Nature communications
Drug repurposing for Alzheimer's disease and other neurodegenerative disorders.
Cummings, JL., et al.
2025,  
bioRxiv : the preprint server for biology
Gene module-trait network analysis uncovers cell type specific systems and genes relevant to Alzheimer's Disease.
de Paiva Lopes, K., et al.
2025,  
medRxiv : the preprint server for health sciences
A Novel Method to Disentangle Tightly Linked Risk and Resilience Genes for Brain Disorders: Application to Alzheimer's Disease.
Barnett, EJ., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Tau pathway-based gene analysis on PET identifies CLU and FYN in a Korean cohort.
Yi, D., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Locus coeruleus tau is linked to successive cortical tau accumulation.
Yi, D., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Transcriptome analysis of early- and late-onset Alzheimer's disease in Korean cohorts.
Han, S., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Moderation of midlife cognitive activity on tau-related cognitive impairment.
Ko, K., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Benchmarking of a multi-biomarker low-volume panel for Alzheimer's disease and related dementia research.
Ibanez, L., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
The association between adult child education and cognitive functioning among older parents: A cross-national comparison of diverse contexts.
Nichols, E., et al.
2025,  
Nature communications
Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility.
Gong, J., et al.
2025,  
Scientific reports
Association of genetic risk of Alzheimer's disease and cognitive function in two European populations.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Association of APOE alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease neuroimaging markers.
Kulminski, AM., et al.
2025,  
medRxiv : the preprint server for health sciences
GWAS links APOE to neuropsychiatric symptoms in mild cognitive impairment and dementia.
Vattathil, SM., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Human herpesvirus-associated transposable element activation in human aging brains with Alzheimer's disease.
Feng, Y., et al.
2025,  
Nature communications
Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease.
Arnold, M., et al.
2025,  
bioRxiv : the preprint server for biology
BTS: scalable Bayesian Tissue Score for prioritizing GWAS variants and their functional contexts across omics data.
Kuksa, PP., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Comparing Alzheimer's genes in African, European, and Amerindian induced pluripotent stem cell-derived microglia.
Moura, S., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Plasma proteomic characterization of motoric cognitive risk and mild cognitive impairment.
Gomez, GT., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Blood biomarkers in Down syndrome: Facilitating Alzheimer's disease detection and monitoring.
Petersen, ME., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Differential associations of neighborhood disadvantage, race/ethnicity, and cognitive status with experiences of psychosocial distress in the HABS-HD cohort.
Rhoads, T., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Alzheimer's disease plasma biomarkers and physical functioning in a diverse sample of adults.
Knell, G., et al.
2025,  
Cell
Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes.
Guo, JL., et al.
2025,  
medRxiv : the preprint server for health sciences
Somatic and Stem Cell Bank to Study the Contribution of African Ancestry to Dementia: African iPSC Initiative.
Maina, MB., et al.
2025,  
Nature communications
regionalpcs improve discovery of DNA methylation associations with complex traits.
Eulalio, T., et al.
2025,  
Journal of medical imaging (Bellingham, Wash.)
Learning disentangled representations to harmonize connectome network measures.
Newlin, NR., et al.
2025,  
Alzheimer's research & therapy
Plasma phospho-tau217 as a predictive biomarker for Alzheimer's disease in a large south American cohort.
Pandey, N., et al.
2025,  
International journal of medical informatics
Modeling the impact of socioeconomic disparity, biological markers and environmental exposures on phenotypic age using mediation analysis and structural equation models.
Pala, D., et al.
2025,  
Radiology
Open-Source Large Language Models in Radiology: A Review and Tutorial for Practical Research and Clinical Deployment.
Savage, CH., et al.
2025,  
Computers in biology and medicine
Generalizable self-supervised learning for brain CTA in acute stroke.
Dong, Y., et al.
2025,  
Nature communications
Meta-EA: a gene-specific combination of available computational tools for predicting missense variant effects.
Katsonis, P.
2025,  
Genetic epidemiology
Enhancing Gene Expression Predictions Using Deep Learning and Functional Annotations.
Ramprasad, P., et al.
2025,  
Nature genetics
The impact of common and rare genetic variants on bradyarrhythmia development.
Weng, L., et al.
2025,  
IEEE transactions on medical imaging
Multi-Modal Diagnosis of Alzheimer's Disease Using Interpretable Graph Convolutional Networks.
Zhou, H., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Single-microglia transcriptomic transition network-based prediction and real-world patient data validation identifies ketorolac as a repurposable drug for Alzheimer's disease.
Xu, J., et al.
2025,  
NPJ Parkinson's disease
A network-based systems genetics framework identifies pathobiology and drug repurposing in Parkinson's disease.
Dou, L., et al.
2025,  
British journal of pharmacology
Artificial intelligence streamlines scientific discovery of drug-target interactions.
Yang, Y.
2025,  
Science advances
The X chromosome's influences on the human brain.
Jiang, Z., et al.
2025,  
The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association
Rural health research in the 21st century: A commentary on challenges and the role of digital technology.
Moloney, M., et al.
2025,  
medRxiv : the preprint server for health sciences
The Dynamics of Cognitive Decline towards Alzheimer's Disease Progression: Results from ADSP-PHC's Harmonized Cognitive Composites.
Kang, K., et al.
2025,  
Journal of Alzheimer's disease : JAD
A DAT1 gene and APOE ε4 interaction is associated with apathy and structural brain changes in mild cognitive impairment and Alzheimer's disease.
Malik, R., et al.
2025,  
Science advances
Comprehensive characterization of the transcriptional landscape in Alzheimer's disease (AD) brains.
Chen, C., et al.
2025,  
The journal of prevention of Alzheimer's disease
Liver function and Alzheimer's brain pathologies: A longitudinal study: Liver and Alzheimer's pathologies.
Kim, JW., et al.
2025,  
medRxiv : the preprint server for health sciences
Multi-Omics Analysis for Identifying Cell-Type-Specific Druggable Targets in Alzheimer's Disease.
Liu, S., et al.
2025,  
Molecular neurodegeneration
Cell-specific transcriptional signatures of vascular cells in Alzheimer's disease: perspectives, pathways, and therapeutic directions.
Chaudhuri, S., et al.
2025,  
Research square
TrimNN: Characterizing cellular community motifs for studying multicellular topological organization in complex tissues.
Yu, Y., et al.
2025,  
Scientific reports
Parallel median consensus clustering in complex networks.
Hussain, MT., et al.
2025,  
Science signaling
Biotin mitigates the development of manganese-induced, Parkinson's disease-related neurotoxicity in Drosophila and human neurons.
Lai, Y., et al.
2025,  
Immunity
Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus.
Matera, A., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Examination of MGMT as a risk gene for dementia in the Amish.
Main, LR., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Sex and APOE ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease.
Peterson, A., et al.
2025,  
bioRxiv : the preprint server for biology
Sex-specific Associations of Gene Expression with Alzheimer's Disease Neuropathology and Ante-mortem Cognitive Performance.
Seto, M., et al.
2025,  
medRxiv : the preprint server for health sciences
Evaluating the association of APOE genotype and cognitive resilience in SuperAgers.
Durant, A., et al.
2025,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Association between dietary inflammatory index score and incident dementia.
van Lent, DM., et al.
2025,  
Nature communications
Polygenic burden of short tandem repeat expansions promotes risk for Alzheimer's disease.
Guo, MH., et al.
2025,  
Dementia and geriatric cognitive disorders
Differential Item Functioning and Clinical Utility of the Subjective Memory Complaints Questionnaire in a Multi-Ethnic Cohort.
Ochoa Lopez, AP., et al.
2025,  
Alzheimer's & dementia (New York, N. Y.)
Characterization of plasma AT(N) biomarkers among a racial and ethnically diverse community-based cohort: an HABS-HD study.
Petersen, ME., et al.
2025,  
Alzheimer's & dementia (New York, N. Y.)
Predictive value and weight of factors associated with cognitive performance in Hispanics/Latinos enrolled in the Health and Aging Brain Study: Health Disparities.
Vintimilla, R., et al.
2025,  
PloS one
Patient stratification by genetic risk in Alzheimer's disease is only effective in the presence of phenotypic heterogeneity.
Euesden, J., et al.
2025,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Astrocyte Reactivity Polygenic Risk Score May Predict Cognitive Decline in Alzheimer's Disease.
Phillips, JM., et al.
2025,  
NPJ dementia
DNA methylation age from peripheral blood predicts progression to Alzheimer's disease, white matter disease burden, and cortical atrophy.
Bonham, LW., et al.
2025,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Multi-modal Imaging-based Pseudotime Analysis of Alzheimer progression.
He, B., et al.
2025,  
International journal of human-computer interaction
Exploring the Early Adoption of Open AI among Laypeople and Technical Professionals: An Analysis of Twitter Conversations on #ChatGPT and #GPT3.
Zou, W., et al.
2025,  
Journal of electrocardiology
A novel electrocardiogram-based model for prediction of dementia-The Atherosclerosis Risk in Communities (ARIC) study.
Chen, D., et al.
2025,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
The Impact of Ancestry on Genome-Wide Association Studies.
Jones, SC., et al.
2025,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Connecting intermediate phenotypes to disease using multi-omics in heart failure.
Moore, A., et al.
2025,  
Frontiers in genetics
Enhancing the utility of polygenic scores in Alzheimer's disease through systematic curation and annotation.
Mwesigwa, S., et al.
2025,  
Computational and structural biotechnology journal
Deep5mC: Predicting 5-methylcytosine (5mC) methylation status using a deep learning transformer approach.
Kinnear, E., et al.
2025,  
PloS one
Research participants' perception of ethical issues in stroke genomics and neurobiobanking research in Africa.
Jegede, A., et al.
2025,  
Journal of Alzheimer's disease reports
Normative data for the CERAD verbal episodic memory tests in a sample of older illiterate Korean women.
Ahn, H., et al.
2025,  
Frontiers in aging neuroscience
Deciphering novel mitochondrial signatures: multi-omics analysis uncovers cross-disease markers and oligodendrocyte pathways in Alzheimer's disease and glioblastoma.
Xu, X., et al.
2025,  
Alzheimer's & dementia (New York, N. Y.)
LD-informed deep learning for Alzheimer's gene loci detection using WGS data.
Jo, T., et al.
2024
2024,  
Journal of the International Neuropsychological Society : JINS
Impact of white matter hyperintensity volume on cognition among US Mexican American adults.
Graves, LV., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Dementia risk scores, apolipoprotein E, and risk of Alzheimer's disease: One size does not fit all.
Andrews, SJ., et al.
2024,  
Journal of chemical theory and computation
Accounting for Fast vs Slow Exchange in Single Molecule FRET Experiments Reveals Hidden Conformational States.
Miller, JJ., et al.
2024,  
Nature neuroscience
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery.
Bonev, B., et al.
2024,  
International journal of obesity (2005)
Effects of high fat diet on metabolic health vary by age of menopause onset.
Salinero, AE., et al.
2024,  
Nature genetics
Genetic architecture of cerebrospinal fluid and brain metabolite levels and the genetic colocalization of metabolites with human traits.
Wang, C., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Pathway enrichment in genome-wide analysis of longitudinal Alzheimer's disease biomarker endophenotypes.
Rosewood, TJ., et al.
2024,  
ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine
Causality-based Subject and Task Fingerprints using fMRI Time-series Data.
IEEE transactions on pattern analysis and machine intelligence
Novel Uncertainty Quantification Through Perturbation-Assisted Sample Synthesis.
Liu, Y., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
The Alzheimer's Disease Neuroimaging Initiative-4 (ADNI-4) Engagement Core: A culturally informed, community-engaged research (CI-CER) model to advance brain health equity.
Rivera Mindt, M., et al.
2024,  
medRxiv : the preprint server for health sciences
A One-Shot Lossless Algorithm for Cross-Cohort Learning in Mixed-Outcomes Analysis.
Li, R., et al.
2024,  
Targets (Basel)
Repurposing FDA-Approved Drugs Against Potential Drug Targets Involved in Brain Inflammation Contributing to Alzheimer's Disease.
Sharo, C., et al.
2024,  
Neurochemistry international
Ras, RhoA, and vascular pharmacology in neurodevelopment and aging.
Nussinov, R., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Association of amyloid and cardiovascular risk with cognition: Findings from KBASE.
Chaudhuri, S., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genome-wide transcriptome analysis of Aβ deposition on PET in a Korean cohort.
Park, T., et al.
2024,  
bioRxiv : the preprint server for biology
Cell Type Differentiation Using Network Clustering Algorithms.
Nasrollahi, FSF., et al.
2024,  
Nature genetics
Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease.
Western, D., et al.
2024,  
Nature neuroscience
Integrated multimodal cell atlas of Alzheimer's disease.
Gabitto, MI., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Whole-genome sequencing study in Koreans identifies novel loci for Alzheimer's disease.
Kang, M., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project.
Lee, W., et al.
2024,  
Research square
Ancestral Genomic Functional Differences in Oligodendroglia: Implications for Alzheimer's Disease.
Ramirez, AM., et al.
2024,  
medRxiv : the preprint server for health sciences
Long Sleep Duration, Cognitive Performance, and the Moderating Role of Depression: A Cross-Sectional Analysis in the Framingham Heart Study.
Young, VM., et al.
2024,  
medRxiv : the preprint server for health sciences
LD-informed deep learning for Alzheimer's gene loci detection using WGS data.
Jo, T., et al.
2024,  
medRxiv : the preprint server for health sciences
NIAGADS: A Comprehensive National Data Repository for Alzheimer's Disease and Related Dementia Genetics and Genomics Research.
Alzheimer's & dementia : the journal of the Alzheimer's Association
The Health Equity Scholars Program: Fostering Culturally Competent and Successful Independent Investigators in Alzheimer's Disease and Related Dementia Research.
Amaza, H., et al.
2024,  
Brain, behavior, and immunity
CD8+ T cells exacerbate AD-like symptoms in mouse model of amyloidosis
Wang, X., et al.
2024,  
Journal of the International Neuropsychological Society : JINS
Heterogeneity in cognitive profiles of monolingual and bilingual Hispanic/Latino older adults in HABS-HD.
Clark, AL., et al.
2024,  
Journal of Alzheimer's disease : JAD
Neurofilament light and cognition in community-dwelling non-Hispanic Blacks.
Abdullah, L., et al.
2024,  
Nature aging
Diagnosis of Alzheimer's disease using plasma biomarkers adjusted to clinical probability.
Therriault, J., et al.
2024,  
bioRxiv : the preprint server for biology
CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions.
Li, E., et al.
2024,  
Acta neuropathologica
Pathologic and clinical correlates of region-specific brain GFAP in Alzheimer's disease.
Phillips, JM., et al.
2024,  
bioRxiv : the preprint server for biology
TIA1 Mediates Divergent Inflammatory Responses to Tauopathy in Microglia and Macrophages.
Webber, CJ., et al.
2024,  
medRxiv : the preprint server for health sciences
Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American Populations.
Acosta-Uribe, J., et al.
2024,  
BioData mining
Deciphering the tissue-specific functional effect of Alzheimer risk SNPs with deep genome annotation.
Pugalenthi, PV., et al.
2024,  
Genetics
Trait imputation enhances nonlinear genetic prediction for some traits.
He, R., et al.
2024,  
Nature genetics
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.
García-Marín, LM., et al.
2024,  
JMIR formative research
Exploring the Perspectives of Older Adults on a Digital Brain Health Platform Using Natural Language Processing: Cohort Study.
Ding, H., et al.
2024,  
bioRxiv : the preprint server for biology
CASTER-DTA: Equivariant Graph Neural Networks for Predicting Drug-Target Affinity.
Kumar, R., et al.
2024,  
Genes
Is the Relationship Between Cardiovascular Disease and Alzheimer's Disease Genetic? A Scoping Review.
Moore, A.
2024,  
Briefings in bioinformatics
QOT: Quantized Optimal Transport for sample-level distance matrix in single-cell omics.
Wang, Z., et al.
2024,  
NPJ systems biology and applications
Network medicine informed multiomics integration identifies drug targets and repurposable medicines for Amyotrophic Lateral Sclerosis.
Yu, M., et al.
2024,  
Nature neuroscience
Integration across biophysical scales identifies molecular and cellular correlates of person-to-person variability in human brain connectivity.
Ng, B., et al.
2024,  
medRxiv : the preprint server for health sciences
Mapping rare protein-coding variants on multi-organ imaging traits.
Fan, Y., et al.
2024,  
Scientific reports
De-identification is not enough: a comparison between de-identified and synthetic clinical notes.
Sarkar, AR., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Integrating amyloid imaging and genetics for early risk stratification of Alzheimer's disease.
He, B., et al.
2024,  
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
Visual and Auditory Sensory Impairments Differentially Relate with Alzheimer's Pathology.
Byeon, G., et al.
2024,  
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
The Moderating Effect of Serum Vitamin D on the Relationship between Beta-amyloid Deposition and Neurodegeneration.
Park, J., et al.
2024,  
Nature communications
Network community detection via neural embeddings.
Kojaku, S., et al.
2024,  
Movement disorders : official journal of the Movement Disorder Society
Genetic Risk Factors in Isolated Dystonia Escape Genome-Wide Association Studies.
Laabs, B., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genetic analysis of cognitive preservation in the midwestern Amish reveals a novel locus on chromosome 2.
Main, LR., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Missense and loss-of-function variants at GWAS loci in familial Alzheimer's disease.
Gunasekaran, TI., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers.
Liu, S., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
The plasma miRNAome in ADNI: Signatures to aid the detection of at-risk individuals.
Krüger, DM., et al.
2024,  
Genome research
High-coverage nanopore sequencing of samples from the 1000 Genomes Project to build a comprehensive catalog of human genetic variation.
Gustafson, JA., et al.
2024,  
Nature communications
Genetic risk factors underlying white matter hyperintensities and cortical atrophy.
Patel, Y., et al.
2024,  
medRxiv : the preprint server for health sciences
Biobank-scale characterization of Alzheimer's disease and related dementias identifies potential disease-causing variants, risk factors, and genetic modifiers across diverse ancestries.
Khani, M., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Widespread transposable element dysregulation in human aging brains with Alzheimer's disease.
Feng, Y., et al.
2024,  
Nature genetics
GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia.
Shade, LMP., et al.
2024,  
Research square
DNA Methylation Signature of a Lifestyle-based Resilience Index for Cognitive Health.
Zhang, W., et al.
2024,  
medRxiv : the preprint server for health sciences
Distinct medical and substance use histories associate with cognitive decline in Alzheimer's Disease.
Mansel, C., et al.
2024,  
bioRxiv : the preprint server for biology
CHARMER: detecting and harmonizing high-confidence chromatin interactions across tissues and Hi-C protocols.
Cole, S., et al.
2024,  
Briefings in bioinformatics
iDOMO: identification of drug combinations via multi-set operations for treating diseases.
Zhou, X., et al.
2024,  
Journal of Alzheimer's disease : JAD
Circulating adipokines and MRI markers of brain aging in middle-aged adults from the community.
Satizabal, CL., et al.
2024,  
bioRxiv : the preprint server for biology
Integrative Network Analysis Reveals Novel Moderators of Aβ-Tau Interaction in Alzheimer's Disease.
Kitani, A.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Cognitive resilience to Alzheimer's disease characterized by cell-type abundance.
O'Neill, N., et al.
2024,  
bioRxiv : the preprint server for biology
African origin haplotype protective for Alzheimer's disease in APOEε4 carriers: exploring potential mechanisms.
Bertholim-Nasciben, L., et al.
2024,  
Alzheimer's research & therapy
Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites.
Tong, T., et al.
2024,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Adaptive Subtype and Stage Inference for Alzheimer's Disease.
Wang, X.
2024,  
Immunological reviews
Current insights into apolipoprotein E and the immune response in Alzheimer's disease.
Lin, PB.
2024,  
bioRxiv : the preprint server for biology
Human-mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome.
Exploring Cellular Heterogeneity: Single-Cell and Spatial Transcriptomics of Alzheimer Disease Brains and iPSC-Derived Microglia.
Garg, A., et al.
2024,  
Trends in molecular medicine
Does glial lipid dysregulation alter sleep in Alzheimer's and Parkinson's disease?
Goodman, LD., et al.
2024,  
Human molecular genetics
Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity.
Pavešković, M., et al.
2024,  
medRxiv : the preprint server for health sciences
Cross-Linguistic Analysis of Speech Markers: Insights from English, Chinese, and Italian Speakers.
Santi, GC., et al.
2024,  
Research square
DNA methylation age from peripheral blood predicts progression to Alzheimer's disease, white matter disease burden, and cortical atrophy.
Bonham, L., et al.
2024,  
Nature medicine
Brain aging patterns in a large and diverse cohort of 49,482 individuals.
Yang, Z., et al.
2024,  
Informatics for health & social care
Identifying biological markers and sociodemographic factors that influence the gap between phenotypic and chronological ages.
Pala, D., et al.
2024,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Self-guided Knowledge-Injected Graph Neural Network for Alzheimer's Diseases.
Wang, Z., et al.
2024,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Interpretable Spatio-Temporal Embedding for Brain Structural-Effective Network with Ordinary Differential Equation.
Tang, H., et al.
2024,  
European heart journal
The AORTA Gene score for detection and risk stratification of ascending aortic dilation.
Pirruccello, JP., et al.
2024,  
JMIR aging
Assessment of Wearable Device Adherence for Monitoring Physical Activity in Older Adults: Pilot Cohort Study.
Ding, H., et al.
2024,  
Medical image analysis
Interpretable deep clustering survival machines for Alzheimer's disease subtype discovery.
Hou, B., et al.
2024,  
BioData mining
Assessing the limitations of relief-based algorithms in detecting higher-order interactions.
Freda, PJ., et al.
2024,  
BioData mining
Deep learning-based approaches for multi-omics data integration and analysis.
Ballard, JL., et al.
2024,  
BioData mining
PAGER: A novel genotype encoding strategy for modeling deviations from additivity in complex trait association studies.
Freda, PJ., et al.
2024,  
Research square
Genome wide association studies are enriched for interacting genes.
Nguyen, PT., et al.
2024,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Volume-optimal persistence homological scaffolds of hemodynamic networks covary with MEG theta-alpha aperiodic dynamics.
Nguyen, N., et al.
2024,  
Current opinion in chemical biology
Neuroprotective signaling by hydrogen sulfide and its dysregulation in Alzheimer's disease.
Paul, BD.
2024,  
Nature biotechnology
A structurally informed human protein-protein interactome reveals proteome-wide perturbations caused by disease mutations.
Xiong, D., et al.
2024,  
Research square
A network-based systems genetics framework identifies pathobiology and drug repurposing in Parkinson's disease.
Dou, L., et al.
2024,  
Bioinformatics (Oxford, England)
GENEVIC: GENetic data Exploration and Visualization via Intelligent interactive Console.
Nath, A., et al.
2024,  
Genome research
Dynamic dysregulation of retrotransposons in neurodegenerative diseases at the single-cell level.
Deng, W., et al.
2024,  
bioRxiv : the preprint server for biology
Methylation Clocks Do Not Predict Age or Alzheimer's Disease Risk Across Genetically Admixed Individuals.
Cruz-González, S., et al.
2024,  
medRxiv : the preprint server for health sciences
Genome-wide scan of Flortaucipir PET levels finds JARID2 associated with cerebral tau deposition.
Gunasekaran, TI., et al.
2024,  
Cell
CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease.
Shen, Y., et al.
2024,  
Research square
Polygenic proxies of age-related plasma protein levels reveal TIMP2 role in cognitive performance.
Anastasi, F., et al.
2024,  
bioRxiv : the preprint server for biology
Cytokine-induced reprogramming of human macrophages toward Alzheimer's disease-relevant molecular and cellular phenotypes in vitro.
Podlesny-Drabiniok, A., et al.
2024,  
Nature biotechnology
Detection of mosaic and population-level structural variants with Sniffles2.
Smolka, M., et al.
2024,  
Nature biotechnology
Comprehensive genome analysis and variant detection at scale using DRAGEN.
Behera, S., et al.
2024,  
bioRxiv : the preprint server for biology
An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration.
Leventhal, MJ., et al.
2024,  
Nature neuroscience
Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress.
Goodman, LD., et al.
2024,  
Acta neuropathologica
Hypothesis-based investigation of known AD risk variants reveals the genetic underpinnings of neuropathological lesions observed in Alzheimer's-type dementia.
Laureyssen, C., et al.
2024,  
JAMA network open
Derivation of Indices of Cognitive Change Among Hispanic Adults and Elders.
Duff, K., et al.
2024,  
Neuroscience
A transient brain endothelial translatome response to endotoxin is associated with mild cognitive changes post-shock in young mice.
Lu, S., et al.
2024,  
PLoS computational biology
pyPAGE: A framework for Addressing biases in gene-set enrichment analysis-A case study on Alzheimer's disease.
Bakulin, A., et al.
2024,  
medRxiv : the preprint server for health sciences
Characterizing patterns of diffusion tensor imaging variance in aging brains.
Gao, C., et al.
2024,  
Magnetic resonance imaging
MidRISH: Unbiased harmonization of rotationally invariant harmonics of the diffusion signal.
Newlin, NR., et al.
2024,  
American journal of speech-language pathology
Applications of the R.A.I.S.E. Assessment Framework to Support the Process of Assessment in Primary Progressive Aphasia.
Gallée, J., et al.
2024,  
Nature
Cellular communities reveal trajectories of brain ageing and Alzheimer's disease.
Green, GS., et al.
2024,  
bioRxiv : the preprint server for biology
gsQTL: Associating genetic risk variants with gene sets by exploiting their shared variability.
Bouland, GA., et al.
2024,  
Journal of neurochemistry
The complexity of extracellular vesicles: Bridging the gap between cellular communication and neuropathology.
Tam, S., et al.
2024,  
ArXiv
Adapting Machine Learning Diagnostic Models to New Populations Using a Small Amount of Data: Results from Clinical Neuroscience.
Wang, R., et al.
2024,  
bioRxiv : the preprint server for biology
Comparison of Explainable AI Models for MRI-based Alzheimer's Disease Classification.
Chattopadhyay, T., et al.
2024,  
The annals of applied statistics
A bootstrap model comparison test for identifying genes with context-specific patterns of genetic regulation.
Malakhov, MM., et al.
2024,  
medRxiv : the preprint server for health sciences
Frequency of Variants in Mendelian Alzheimer's Disease Genes within the Alzheimer's Disease Sequencing Project (ADSP).
Wang, D., et al.
2024,  
American heart journal plus : cardiology research and practice
The association of exhaled carbon monoxide with atrial fibrillation and left atrial size in the Framingham Heart Study.
Eromosele, OB., et al.
2024,  
Research square
Assessing the Limitations of Relief-Based Algorithms in Detecting Higher-Order Interactions.
Freda, PJ., et al.
2024,  
IEEE/ACM transactions on computational biology and bioinformatics
MG-TCCA: Tensor Canonical Correlation Analysis across Multiple Groups.
Zhou, Z., et al.
2024,  
medRxiv : the preprint server for health sciences
Language Modeling Screens Parkinson's Disease with Self-reported Questionnaires.
Reyes, DM., et al.
2024,  
Briefings in bioinformatics
A review of feature selection strategies utilizing graph data structures and Knowledge Graphs.
Shao, S., et al.
2024,  
medRxiv : the preprint server for health sciences
The Interaction Effects of Sex, Age, APOE and Common Health Risk Factors on Human Brain Functions.
Li, T., et al.
2024,  
Aging cell
An interpretable machine learning-based cerebrospinal fluid proteomics clock for predicting age reveals novel insights into brain aging.
Melendez, J., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
A genetic and proteomic comparison of key AD biomarkers across tissues.
Marsh, TW., et al.
2024,  
Environmental health perspectives
Seminar: Functional Exposomics and Mechanisms of Toxicity-Insights from Model Systems and NAMs.
Lai, Y., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference.
Kloske, CM., et al.
2024,  
Translational psychiatry
Chromosome X-wide association study in case control studies of pathologically confirmed Alzheimer's disease in a European population.
Simmonds, E., et al.
2024,  
Communications biology
AutoFocus: a hierarchical framework to explore multi-omic disease associations spanning multiple scales of biomolecular interaction.
Schweickart, A., et al.
2024,  
Nature communications
Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes.
Farrell, K., et al.
2024,  
Translational psychiatry
Causal relationships between dyslexia and the risk of eight dementias.
Zhu, P., et al.
2024,  
Nature communications
CYP1B1-RMDN2 Alzheimer's disease endophenotype locus identified for cerebral tau PET.
Nho, K., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Admixture mapping of cognitive function in diverse Hispanic and Latino adults: Results from the Hispanic Community Health Study/Study of Latinos.
Xia, R., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
A genome-wide association meta-analysis of all-cause and vascular dementia.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Leptin bioavailability and markers of brain atrophy and vascular injury in the middle age.
Charisis, S., et al.
2024,  
Communications biology
Genome-wide association study meta-analysis of neurofilament light (NfL) levels in blood reveals novel loci related to neurodegeneration.
Ahmad, S., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup.
Jack, CR., et al.
2024,  
Nature medicine
Revised criteria for the diagnosis and staging of Alzheimer's disease.
Jack, CR., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Sex and gender differences in cognitive resilience to aging and Alzheimer's disease.
Arenaza-Urquijo, EM., et al.
2024,  
Hormones and behavior
Treatment with brain specific estrogen prodrug ameliorates cognitive effects of surgical menopause in mice.
Salinero, AE., et al.
2024,  
medRxiv : the preprint server for health sciences
Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication.
Zhao, X., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Florbetaben amyloid PET acquisition time: Influence on Centiloids and interpretation.
Johns, E., et al.
2024,  
Scientific reports
Global perspectives on the management of primary progressive aphasia.
Gallée, J., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
An ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome.
Snyder, A., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Assessing the lack of diversity in genetics research across neurodegenerative diseases: A systematic review of the GWAS Catalog and literature.
Jonson, C., et al.
2024,  
Research square
Variable and interactive effects of Sex, APOE ε4 and TREM2 on the deposition of tau in entorhinal and neocortical regions
2024,  
medRxiv : the preprint server for health sciences
Country Level Incidence of Alzheimer Disease and Related Dementias is Associated with Increased Omega6 PUFA Consumption.
Ciesielski, TH., et al.
2024,  
bioRxiv : the preprint server for biology
Amyloid, Tau, and APOE in Alzheimer's Disease: Impact on White Matter Tracts.
Chandio, BQ., et al.
2024,  
American journal of human genetics
Inferring causal direction between two traits using R2 with application to transcriptome-wide association studies
2024,  
Human molecular genetics
Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium.
Jiang, M., et al.
2024,  
JMIR aging
Detection of Mild Cognitive Impairment From Non-Semantic, Acoustic Voice Features: The Framingham Heart Study.
Ding, H., et al.
2024,  
Annual review of biomedical data science
Centralized and Federated Models for the Analysis of Clinical Data.
Li, R., et al.
2024,  
Annual review of biomedical data science
Employing Informatics Strategies in Alzheimer's Disease Research: A Review from Genetics, Multiomics, and Biomarkers to Clinical Outcomes.
Bao, J., et al.
2024,  
medRxiv : the preprint server for health sciences
Connecting intermediate phenotypes to disease using multi-omics in heart failure.
Moore, A., et al.
2024,  
Research square
Single-nucleus multiome analysis of human cerebellum in Alzheimer's disease-related dementia.
Cheng, F., et al.
2024,  
Molecular psychiatry
Genetic overlap between Alzheimer's disease and immune-mediated diseases: an atlas of shared genetic determinants and biological convergence.
Enduru, N., et al.
2024,  
Research square
Single-nucleus multiomics reveals the disrupted regulatory programs in three brain regions of sporadic early-onset Alzheimer's disease.
Zhao, Z., et al.
2024,  
medRxiv : the preprint server for health sciences
Structural variants linked to Alzheimer's Disease and other common age-related clinical and neuropathologic traits.
Vialle, RA., et al.
2024,  
bioRxiv : the preprint server for biology
Scupa: Single-cell unified polarization assessment of immune cells using the single-cell foundation model.
Liu, W.
2024,  
medRxiv : the preprint server for health sciences
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.
García-Marín, LM., et al.
2024,  
Research square
Region-based analysis with functional annotation identifies genes associated with cognitive function in South Asians from India.
Abu-Amara, H., et al.
2024,  
Acta neuropathologica
Epigenetic and genetic risk of Alzheimer disease from autopsied brains in two ethnic groups.
Ma, Y., et al.
2024,  
Nature communications
SR-TWAS: leveraging multiple reference panels to improve transcriptome-wide association study power by ensemble machine learning.
Parrish, RL., et al.
2024,  
bioRxiv : the preprint server for biology
BLEND: Probabilistic Cellular Deconvolution with Automated Reference Selection.
Huang, P., et al.
2024,  
Molecular neurodegeneration
Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy.
Wang, H., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.
Ray, NR., et al.
2024,  
Scientific reports
Targeted co-expression networks for the study of traits.
Gómez-Pascual, A., et al.
2024,  
medRxiv : the preprint server for health sciences
A Specialized Reference Panel with Structural Variants Integration for Improving Genotype Imputation in Alzheimer's Disease and Related Dementias (ADRD).
Cheng, P., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Concurrent nutrient deficiencies are associated with dementia incidence.
van Soest, APM., et al.
2024,  
Stem cell research & therapy
Secretome from iPSC-derived MSCs exerts proangiogenic and immunosuppressive effects to alleviate radiation-induced vascular endothelial cell damage.
Gupta, K., et al.
2024,  
Brain, behavior, and immunity
Temporal tau asymmetry spectrum influences divergent behavior and language patterns in Alzheimer's disease.
Younes, K., et al.
2024,  
Journal of medical imaging (Bellingham, Wash.)
Characterizing patterns of diffusion tensor imaging variance in aging brains.
Gao, C., et al.
2024,  
Biological psychiatry
A Single-Nucleus Transcriptome-Wide Association Study Implicates Novel Genes in Depression Pathogenesis.
Zeng, L., et al.
2024,  
Annals of neurology
Evaluating the Effect of Alzheimer's Disease-Related Biomarker Change in Corticobasal Syndrome and Progressive Supranuclear Palsy.
Garcia-Cordero, I., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Expansion of highly interferon-responsive T cells in early-onset Alzheimer's disease.
Sirkis, DW., et al.
2024,  
Pathogens (Basel, Switzerland)
Dementia Prevalence and Onchocerca volvulus Infection among Rural Elderly Persons in the Ntui Health District, Cameroon: A Population-Based Study.
Njamnshi, WY., et al.
2024,  
ArXiv
A principled framework to assess the information-theoretic fitness of brain functional sub-circuits.
Duong-Tran, D., et al.
2024,  
Nature communications
A robust cis-Mendelian randomization method with application to drug target discovery.
Lin, Z.
2024,  
JMIR biomedical engineering
Agreement Between Apple Watch and Actical Step Counts in a Community Setting: Cross-Sectional Investigation From the Framingham Heart Study.
Spartano, NL., et al.
2024,  
ArXiv
MotifbreakR v2: extended capability and database integration.
Coetzee, SG.
2024,  
ArXiv
Volume-optimal persistence homological scaffolds of hemodynamic networks covary with MEG theta-alpha aperiodic dynamics.
Nguyen, N., et al.
2024,  
NPJ digital medicine
Identification of Parkinson's disease PACE subtypes and repurposing treatments through integrative analyses of multimodal data.
Su, C., et al.
2024,  
medRxiv : the preprint server for health sciences
GRPa-PRS: A risk stratification method to identify genetically-regulated pathways in polygenic diseases.
Li, X., et al.
2024,  
HGG advances
DeepFace: Deep-learning-based framework to contextualize orofacial-cleft-related variants during human embryonic craniofacial development.
Dai, Y., et al.
2024,  
Nature communications
Eye-brain connections revealed by multimodal retinal and brain imaging genetics.
Zhao, B., et al.
2024,  
Human brain mapping
Brain-age prediction: Systematic evaluation of site effects, and sample age range and size.
Yu, Y., et al.
2024,  
Alzheimer's research & therapy
Moderation of thyroid hormones for the relationship between amyloid and tau pathology.
Byeon, JH., et al.
2024,  
Scientific reports
Iterative embedding and reweighting of complex networks reveals community structure.
Kovács, B., et al.
2024,  
Aging
Association between osteoporosis and the rate of telomere shortening.
Han, M., et al.
2024,  
Scientific reports
Peripheral inflammation is associated with brain atrophy and cognitive decline linked to mild cognitive impairment and Alzheimer's disease.
Liang, N., et al.
2024,  
Cerebral cortex (New York, N.Y. : 1991)
Multiparameter cortical surface morphology in former amateur contact sport athletes.
Recht, G., et al.
2024,  
medRxiv : the preprint server for health sciences
Missense and Loss of Function Variants at GWAS Loci in Familial Alzheimer's Disease.
Gunasekaran, TI., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Post-GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease highlights a potential role for GPX3.
Panyard, DJ., et al.
2024,  
Scientific data
Genetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research Center.
Fernandez, MV., et al.
2024,  
medRxiv : the preprint server for health sciences
A Comprehensive Head-to-Head Comparison of Key Plasma Phosphorylated Tau 217 Biomarker Tests.
Warmenhoven, N., et al.
2024,  
Research square
Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease.
Debette, S., et al.
2024,  
Research square
Ubiquitin-Proteasome System in the Different Stages of Dominantly Inherited Alzheimer's Disease.
McDade, E., et al.
2024,  
Research square
European and African-specific plasma protein-QTL and metabolite-QTL analyses identify ancestry-specific T2D effector proteins and metabolites.
Cruchaga, C., et al.
2024,  
Environmental science & technology
High-Resolution Mass Spectrometry for Human Exposomics: Expanding Chemical Space Coverage.
Lai, Y., et al.
2024,  
medRxiv : the preprint server for health sciences
Ancestry specific distribution of LPA Kringle IV-Type-2 genetic variants highlight associations to apo(a) copy number, glucose, and hypertension.
Li, Y., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Considerations for the use of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) in cross-country comparisons of cognitive aging and dementia.
Nichols, E., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Effect of apolipoprotein E ε4 and its modification by sociodemographic characteristics on cognitive measures in South Asians from LASI-DAD.
Wang, YZ., et al.
2024,  
Journal of medical imaging (Bellingham, Wash.)
Field-of-view extension for brain diffusion MRI via deep generative models.
Gao, C., et al.
2024,  
ArXiv
Diffusion Model-based FOD Restoration from High Distortion in dMRI.
Huang, S., et al.
2024,  
Neuron
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Litvinchuk, A., et al.
2024,  
Research square
Midkine Attenuates Aβ Fibril Assembly and AmyloidPlaque Formation.
Peng, J., et al.
2024,  
bioRxiv : the preprint server for biology
Accounting for fast vs slow exchange in single molecule FRET experiments reveals hidden conformational states.
Miller, JJ., et al.
2024,  
Trends in cell biology
Decoding polygenic diseases: advances in noncoding variant prioritization and validation.
Chin, IM., et al.
2024,  
Hormones and behavior
Androgen regulation of behavioral stress responses and the hypothalamic-pituitary-adrenal axis.
Zuloaga, DG., et al.
2024,  
bioRxiv : the preprint server for biology
Proximity labeling reveals dynamic changes in the SQSTM1 protein network.
Ortiz, ANR., et al.
2024,  
Journal of racial and ethnic health disparities
Multiple Chronic Conditions and Disability among Vietnamese Older Adults: Results from the Vietnamese Aging and Care Survey (VACS).
Miyawaki, CE., et al.
2024,  
Journal of racial and ethnic health disparities
Intersections of Racial/Ethnic and Religious Identities on Bodily Well-Being for Black College-Attending Emerging Adults.
Ross, JM., et al.
2024,  
Annals of neurology
Prevalence of and Annual Conversion Rates to Mild Cognitive Impairment and Dementia: Prospective, Longitudinal Study of an Essential Tremor Cohort.
Ghanem, A., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden.
Levin, J., et al.
2024,  
JAMA neurology
Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial.
Wagemann, O., et al.
2024,  
Nature reviews. Neurology
The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology.
Benatar, M., et al.
2024,  
Nature reviews. Neurology
Publisher Correction: The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology.
Benatar, M., et al.
2024,  
IEEE transactions on neural networks and learning systems
Contrastive Brain Network Learning via Hierarchical Signed Graph Pooling Model.
Tang, H., et al.
2024,  
bioRxiv : the preprint server for biology
Evaluation of enzyme activity predictions for variants of unknown significance in Arylsulfatase A.
Jain, S., et al.
2024,  
Journal of the American Heart Association
Bidirectional Association Between Atrial Fibrillation and Myocardial Infarction, and Relation to Mortality in the Framingham Heart Study.
Frederiksen, TC., et al.
2024,  
Journal of medical Internet research
Association of Smartwatch-Based Heart Rate and Physical Activity With Cardiorespiratory Fitness Measures in the Community: Cohort Study.
Zhang, Y., et al.
2024,  
Bioinformatics (Oxford, England)
KRAGEN: a knowledge graph-enhanced RAG framework for biomedical problem solving using large language models.
Matsumoto, N., et al.
2024,  
Molecular neurodegeneration
Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.
Parra Bravo, C., et al.
2024,  
Annals of statistics
ON BLOCKWISE AND REFERENCE PANEL-BASED ESTIMATORS FOR GENETIC DATA PREDICTION IN HIGH DIMENSIONS.
Zhao, B., et al.
2024,  
medRxiv : the preprint server for health sciences
Benchmarking of a multi-biomarker low-volume panel for Alzheimer's Disease and related dementia research.
Ibanez, L., et al.
2024,  
Nature communications
Gliovascular transcriptional perturbations in Alzheimer's disease reveal molecular mechanisms of blood brain barrier dysfunction.
2024,  
bioRxiv : the preprint server for biology
Sex, racial, and APOE-ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease.
Peterson, A., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Metabolomics profiling reveals distinct, sex-specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease.
Pandey, RS., et al.
2024,  
Research square
Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracell signaling pathways.
Cruchaga, C., et al.
2024,  
The neuroradiology journal
Association of brain arterial diameters with demographic and anatomical factors in a multi-national pooled analysis of cohort studies.
Del Brutto, VJ., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact.
Montelukast as a repurposable additive drug for standard-efficacy multiple sclerosis treatment: Emulating clinical trials with retrospective administrative health claims data.
Manuel, AM., et al.
2024,  
JAMA network open
Plasma Leptin and Alzheimer Protein Pathologies Among Older Adults.
Lee, S., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Key variants via the Alzheimer's Disease Sequencing Project whole genome sequence data.
Wang, Y., et al.
2024,  
medRxiv : the preprint server for health sciences
SR-TWAS: Leveraging Multiple Reference Panels to Improve TWAS Power by Ensemble Machine Learning.
Brain cell-type shifts in Alzheimer's disease, autism, and schizophrenia interrogated using methylomics and genetics.
Yap, CX., et al.
2024,  
eLife
Biobank-wide association scan identifies risk factors for late-onset Alzheimer's disease and endophenotypes.
Yan, D., et al.
2024,  
Briefings in bioinformatics
CWAS-Plus: estimating category-wide association of rare noncoding variation from whole-genome sequencing data with cell-type-specific functional data.
Kim, Y., et al.
2024,  
Nature communications
Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes.
Keener, R., et al.
2024,  
Cell reports. Medicine
Genetic variants for head size share genes and pathways with cancer.
Knol, MJ., et al.
2024,  
Life science alliance
A comparative study of structural variant calling in WGS from Alzheimer's disease families.
Malamon, JS., et al.
2024,  
Human brain mapping
Diffusion MRI harmonization via personalized template mapping.
Xia, Y.
2024,  
Neuron
Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins.
Strickland, MR., et al.
2024,  
The Journal of experimental medicine
Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy.
Toral-Rios, D., et al.
2024,  
Journal of proteome research
Profiling Protein-Protein Interactions in the Human Brain by Refined Cofractionation Mass Spectrometry.
Shrestha, HK., et al.
2024,  
PLoS biology
Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease.
Eteleeb, AM., et al.
2024,  
Nature neuroscience
Glial lipid droplets resolve ROS during sleep.
Goodman, LD., et al.
2024,  
Neuroinformatics
DeepN4: Learning N4ITK Bias Field Correction for T1-weighted Images.
Kanakaraj, P., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons.
Hsieh, Y., et al.
2024,  
Sleep medicine
Sleep problems as predictors of cognitive decline in essential tremor: A prospective longitudinal cohort study.
Tsapanou, A., et al.
2024,  
JAMA network open
Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration.
Staffaroni, AM., et al.
2024,  
medRxiv : the preprint server for health sciences
Gene specific effects on brain volume and cognition of TMEM106B in frontotemporal lobar degeneration.
Vandebergh, M., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
More than a piece of cake: Noun classifier processing in primary progressive aphasia.
Tee, BL., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Data stewardship in FTLD research: Investigator and research participant views.
Arias, JJ., et al.
2024,  
Communications biology
Unsupervised deep representation learning enables phenotype discovery for genetic association studies of brain imaging.
Patel, K., et al.
2024,  
BMC genomics
Tissue-specific atlas of trans-models for gene regulation elucidates complex regulation patterns.
Dagostino, R.
2024,  
Biostatistics (Oxford, England)
DeLIVR: a deep learning approach to IV regression for testing nonlinear causal effects in transcriptome-wide association studies.
He, R., et al.
2024,  
PLoS genetics
Collider bias correction for multiple covariates in GWAS using robust multivariable Mendelian randomization.
Wang, P., et al.
2024,  
Journal of medical Internet research
The Alzheimer's Knowledge Base: A Knowledge Graph for Alzheimer Disease Research.
Romano, JD., et al.
2024,  
Journal of personalized medicine
Identifying Progression-Specific Alzheimer's Subtypes Using Multimodal Transformer.
Machado Reyes, D., et al.
2024,  
Current opinion in structural biology
Artificial intelligence for drug discovery and development in Alzheimer's disease.
Qiu, Y.
2024,  
PLOS digital health
Deep learning to predict rapid progression of Alzheimer's disease from pooled clinical trials: A retrospective study.
Ma, X., et al.
2024,  
Epigenomes
Unveiling Gene Interactions in Alzheimer's Disease by Integrating Genetic and Epigenetic Data with a Network-Based Approach.
Sanders, KL., et al.
2024,  
Research square
SAFER: sub-hypergraph attention-based neural network for predicting effective responses to dose combinations.
Tang, Y., et al.
2024,  
Science advances
CSF biomarkers of immune activation and Alzheimer's disease for predicting cognitive impairment risk in the elderly.
Shue, F., et al.
2024,  
Scientific data
TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasma.
Yi, H., et al.
2024,  
medRxiv : the preprint server for health sciences
Comparative gene regulatory networks modulating APOE expression in microglia and astrocytes.
Brase, L., et al.
2024,  
medRxiv : the preprint server for health sciences
CWAS-Plus: Estimating category-wide association of rare noncoding variation from whole-genome sequencing data with cell-type-specific functional data.
Kim, Y., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.
Xicota, L., et al.
2024,  
Acta neuropathologica
Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease.
Bhattarai, P., et al.
2024,  
medRxiv : the preprint server for health sciences
Generalizability of Tau and Amyloid Plasma Biomarkers in Alzheimer's Disease Cohorts of Diverse Genetic Ancestries.
Griswold, AJ., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genetic associations with dementia-related proteinopathy: Application of item response theory.
Katsumata, Y., et al.
2024,  
medRxiv : the preprint server for health sciences
The Role of X Chromosome in Alzheimer's Disease Genetics.
Belloy, ME., et al.
2024,  
medRxiv : the preprint server for health sciences
The Role of Genomic-Informed Risk Assessments in Predicting Dementia Outcomes.
Andrews, SJ., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Lewy body dementia: Overcoming barriers and identifying solutions.
Agarwal, K., et al.
2024,  
bioRxiv : the preprint server for biology
Network medicine informed multi-omics integration identifies drug targets and repurposable medicines for Amyotrophic Lateral Sclerosis.
Yu, M., et al.
2024,  
Molecular cancer research : MCR
Single-Cell Transcriptomics Reveals Pre-existing COVID-19 Vulnerability Factors in Lung Cancer Patients.
Liu, W., et al.
2024,  
Journal of biomedical informatics
SPeC: A Soft Prompt-Based Calibration on Performance Variability of Large Language Model in Clinical Notes Summarization.
Chuang, Y., et al.
2024,  
Bioinformatics (Oxford, England)
FPLS-DC: functional partial least squares through distance covariance for imaging genetics.
Pan, W., et al.
2024,  
Current protocols
Data-Independent Acquisition and Label-Free Quantification for Quantitative Proteomics Analysis of Human Cerebrospinal Fluid.
Makepeace, KAT., et al.
2024,  
Neuron
Harnessing diversity to study Alzheimer's disease: A new iPSC resource from the NIH CARD and ADNI.
Screven, LA., et al.
2024,  
Alzheimer's research & therapy
Association between brain amyloid deposition and longitudinal changes of white matter hyperintensities.
Cha, W., et al.
2024,  
medRxiv : the preprint server for health sciences
CSF proteomic profiling with amyloid/tau positivity identifies distinctive sex-different alteration of multiple proteins involved in Alzheimer's disease.
Do, AN., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Risk of Alzheimer's disease is associated with longitudinal changes in plasma biomarkers in the multi-ethnic Washington Heights-Hamilton Heights-Inwood Columbia Aging Project (WHICAP) cohort.
Gu, Y., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Periodontitis and brain magnetic resonance imaging markers of Alzheimer's disease and cognitive aging.
Rubinstein, T., et al.
2024,  
Nature communications
BHLHE40/41 regulate microglia and peripheral macrophage responses associated with Alzheimer's disease and other disorders of lipid-rich tissues.
Podleśny-Drabiniok, A., et al.
2024,  
medRxiv : the preprint server for health sciences
Nanopore sequencing of 1000 Genomes Project samples to build a comprehensive catalog of human genetic variation.
Gustafson, JA., et al.
2024,  
American journal of human genetics
The association of GNB5 with Alzheimer disease revealed by genomic analysis restricted to variants impacting gene function.
Zhang, J., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genome-wide association studies identify novel loci in rapidly progressive Alzheimer's disease.
Wang, P., et al.
2024,  
iScience
AI-enabled evaluation of genome-wide association relevance and polygenic risk score prediction in Alzheimer's disease.
Platt, DE., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
A novel neuroimaging signature for ADRD risk stratification in the community.
Satizabal, CL., et al.
2024,  
Molecular psychiatry
ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism.
Kawatani, K., et al.
2024,  
Nature neuroscience
Microglia enhance post-anesthesia neuronal activity by shielding inhibitory synapses.
Haruwaka, K., et al.
2024,  
Biomolecules
In Silico Investigation of Parkin-Activating Mutations Using Simulations and Network Modeling.
Islam, NN., et al.
2024,  
medRxiv : the preprint server for health sciences
Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease.
Global Perspectives on the Management of Primary Progressive Aphasia.
Gallée, J., et al.
2024,  
Research square
Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration.
Saloner, R., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Asian Cohort for Alzheimer's Disease (ACAD) pilot study on genetic and non-genetic risk factors for Alzheimer's disease among Asian Americans and Canadians.
Ho, P., et al.
2024,  
Angewandte Chemie (International ed. in English)
Mining the Metabolic Capacity of Clostridium sporogenes Aided by Machine Learning.
Ouyang, H., et al.
2024,  
iScience
A self-supervised learning approach for registration agnostic imaging models with 3D brain CTA.
Dong, Y., et al.
2024,  
iScience
Distance-weighted Sinkhorn loss for Alzheimer's disease classification.
Wang, Z., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Plasma Aβ42/Aβ40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease.
Rissman, RA., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Empirically derived psychosocial-behavioral phenotypes in Black/African American and Hispanic/Latino older adults enrolled in HABS-HD: Associations with AD biomarkers and cognitive outcomes.
Clark, AL., et al.
2024,  
Neuron
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Litvinchuk, A., et al.
2024,  
Acta neuropathologica communications
Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer's disease.
Raulin, A., et al.
2024,  
Proceedings of SPIE--the International Society for Optical Engineering
Assessment of Subject Head Motion in Diffusion MRI.
Topolnjak, E., et al.
2024,  
Proceedings of SPIE--the International Society for Optical Engineering
Cell Spatial Analysis in Crohn's Disease: Unveiling Local Cell Arrangement Pattern with Graph-based Signatures.
Bao, S., et al.
2024,  
Proceedings of SPIE--the International Society for Optical Engineering
Predicting Age from White Matter Diffusivity with Residual Learning.
Gao, C., et al.
2024,  
Acta neuropathologica
Scientific commentary on: "Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies".
Oertel, FC., et al.
2024,  
Molecular psychiatry
Cortical microstructural associations with CSF amyloid and pTau.
Nir, TM., et al.
2024,  
bioRxiv : the preprint server for biology
Deep Normative Tractometry for Identifying Joint White Matter Macro- and Micro-structural Abnormalities in Alzheimer's Disease.
Feng, Y., et al.
2024,  
Research square
Deciphering the tissue-specific functional effect of Alzheimer risk SNPs with deep genome annotation.
Pugalenthi, PV., et al.
2024,  
Proceedings of SPIE--the International Society for Optical Engineering
Investigating Causal Genetic Effects on Overall Survival of Glioblastoma Patients using Normalizing Flow and Structural Causal Model.
Yu, F., et al.
2024,  
iScience
Strategies to combine 3D vasculature and brain CTA with deep neural networks: Application to LVO.
Lal-Trehan Estrada, UM., et al.
2024,  
Statistics in medicine
Statistical inference with large-scale trait imputation.
Ren, J.
2024,  
bioRxiv : the preprint server for biology
QOT: Efficient Computation of Sample Level Distance Matrix from Single-Cell Omics Data through Quantized Optimal Transport.
Wang, Z., et al.
2024,  
BioData mining
Interaction models matter: an efficient, flexible computational framework for model-specific investigation of epistasis.
Batista, S., et al.
2024,  
bioRxiv : the preprint server for biology
Structurally-informed human interactome reveals proteome-wide perturbations by disease mutations.
Xiong, D., et al.
2024,  
Cell reports. Medicine
Artificial intelligence and open science in discovery of disease-modifying medicines for Alzheimer's disease.
Cheng, F., et al.
2024,  
Genome medicine
Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans.
Akinyemi, RO., et al.
2024,  
Cell reports
Spatial transcriptomic patterns underlying amyloid-β and tau pathology are associated with cognitive dysfunction in Alzheimer's disease.
Yu, M., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome.
Gorijala, P., et al.
2024,  
Research square
Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures for asymptomatic and symptomatic Alzheimer's disease.
Cruchaga, C., et al.
2024,  
Aging cell
Integrative multi-omics analysis reveals the critical role of the PBXIP1 gene in Alzheimer's disease.
Zhang, J., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Microglial immunometabolism endophenotypes contribute to sex difference in Alzheimer's disease.
Hou, Y., et al.
2024,  
Translational psychiatry
APOE genotype-specific methylation patterns are linked to Alzheimer disease pathology and estrogen response.
Panitch, R., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's disease genetic and genomic knowledge.
Greenfest-Allen, E., et al.
2024,  
medRxiv : the preprint server for health sciences
Association of Structural Forms of 17q21.31 with the Risk of Progressive Supranuclear Palsy and MAPT Sub-haplotypes.
Wang, H., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Sex-specific genetic architecture of late-life memory performance.
Eissman, JM., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease.
Archer, DB., et al.
2024,  
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
Cross-phenotype associations between Alzheimer's Disease and its comorbidities may provide clues to progression.
Moore, A.
2024,  
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
Multivariate mediation analysis with voxel-based morphometry revealed the neurodegeneration pathways from genetic variants to Alzheimer's Disease.
Mu, S., et al.
2024,  
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
Topology-based Clustering of Functional Brain Networks in an Alzheimer's Disease Cohort.
Xu, FH., et al.
2024,  
Journal of Alzheimer's disease : JAD
Sildenafil as a Candidate Drug for Alzheimer's Disease: Real-World Patient Data Observation and Mechanistic Observations from Patient-Induced Pluripotent Stem Cell-Derived Neurons.
Gohel, D., et al.
2024,  
Alzheimer's & dementia (New York, N. Y.)
Alzheimer's disease drug development pipeline: 2024
2024,  
Journal of Alzheimer's disease : JAD
Disentangling Accelerated Cognitive Decline from the Normal Aging Process and Unraveling Its Genetic Components: A Neuroimaging-Based Deep Learning Approach.
Dai, Y., et al.
2024,  
Frontiers in genetics
Dissecting the shared genetic architecture between Alzheimer's disease and frailty: a cross-trait meta-analyses of genome-wide association studies.
Enduru, N., et al.
2024,  
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
FERI: A Multitask-based Fairness Achieving Algorithm with Applications to Fair Organ Transplantation.
Federated Multiple Imputation for Variables that Are Missing Not At Random in Distributed Electronic Health Records.
Lian, Y., et al.
2024,  
Expert review of neurotherapeutics
Current perspectives on prevention of vascular cognitive impairment and promotion of vascular brain health.
Kalaria, RN., et al.
2024,  
Journal of Alzheimer's disease : JAD
Attitudes and Perceptions about Brain Donation Among African Americans: Implications for Recruitment into Alzheimer's Disease Research.
Caban-Holt, A., et al.
2024,  
Journal of Alzheimer's disease : JAD
Does the Cognitive Change Index Predict Future Cognitive and Clinical Decline? Longitudinal Analysis in a Demographically Diverse Cohort.
Nester, CO., et al.
2024,  
Journal of Alzheimer's disease : JAD
Moderation of Amyloid-β Deposition on the Effect of Cholinesterase Inhibitors on Cognition in Mild Cognitive Impairment.
Byeon, G., et al.
2024,  
Frontiers in aging neuroscience
Association of CSF soluble TREM1 levels with hippocampal atrophy in cognitively impaired older adults.
Shu, H., et al.
2024,  
Frontiers in toxicology
Effect of altered production and storage of dopamine on development and behavior in C. elegans.
Lee, I., et al.
2024,  
PloS one
Prevalence of DSM-5 mild and major neurocognitive disorder in India: Results from the LASI-DAD.
Gross, AL., et al.
2024,  
Alzheimer's & dementia (New York, N. Y.)
Genetic associations with psychosis and affective disturbance in Alzheimer's disease.
Antonsdottir, IM., et al.
2024,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Disentangling the genetic underpinnings of neuropsychiatric symptoms in Alzheimer's disease in the Alzheimer's Disease Sequencing Project: Study design and methodology.
Ray, NR., et al.
2024,  
PloS one
Molecular regulation of PPARγ/RXRα signaling by the novel cofactor ZFP407.
Charrier, A., et al.
2024,  
Alzheimer's & dementia (New York, N. Y.)
Genetic and multi-omic risk assessment of Alzheimer's disease implicates core associated biological domains.
Cary, GA., et al.
2024,  
Journal of Alzheimer's disease : JAD
Deep Trans-Omic Network Fusion for Molecular Mechanism of Alzheimer's Disease.
Xie, L., et al.
2024,  
Journal of Alzheimer's disease : JAD
Epistatic Features and Machine Learning Improve Alzheimer's Disease Risk Prediction Over Polygenic Risk Scores.
Hermes, S., et al.
2024,  
JVS-vascular science
Small apolipoprotein(a) isoforms may predict primary patency following peripheral arterial revascularization.
Pavlyha, M., et al.
2024,  
Journal of Alzheimer's disease : JAD
African Ancestry Individuals with Higher Educational Attainment Are Resilient to Alzheimer's Disease Measured by pTau181.
Rajabli, F., et al.
2024,  
Journal of Alzheimer's disease : JAD
Under-Diagnosis of Dementia with Lewy Bodies in Individuals Racialized as Black: Hypotheses Regarding Potential Contributors.
Armstrong, MJ.
2024,  
Cell
APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread.
Chen, Y., et al.
2024,  
bioRxiv : the preprint server for biology
ER and SOCE Ca2+ signals are not required for directed cell migration in human microglia
2024,  
bioRxiv : the preprint server for biology
Effects of High Fat Diet on Metabolic Health Vary by Age of Menopause Onset.
Salinero, AE., et al.
2024,  
Nature communications
OXR1 maintains the retromer to delay brain aging under dietary restriction.
Wilson, KA., et al.
2024,  
ArXiv
Predicting Age from White Matter Diffusivity with Residual Learning.
Gao, C., et al.
2024,  
Medical image analysis
Riemannian frameworks for the harmonization of resting-state functional MRI scans.
Honnorat, N., et al.
2024,  
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Identifying and Diagnosing TDP-43 Neurodegenerative Diseases in Psychiatry.
Ducharme, S., et al.
2024,  
Neurology
Changes in Digital Speech Measures in Asymptomatic Carriers of Pathogenic Variants Associated With Frontotemporal Degeneration.
Nevler, N., et al.
2024,  
medRxiv : the preprint server for health sciences
Psychotic symptoms are associated with elevated tau PET signal in the amygdala independent of Alzheimer's disease clinical severity and amyloid burden.
Johnson, AS., et al.
2024,  
bioRxiv : the preprint server for biology
Expansion of highly interferon-responsive T cells in early-onset Alzheimer's disease.
Sirkis, DW., et al.
2024,  
medRxiv : the preprint server for health sciences
Assessing the lack of diversity in genetics research across neurodegenerative diseases: a systematic review of the GWAS Catalog and literature.
Jonson, C., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Identifying individuals with non-Alzheimer's disease co-pathologies: A precision medicine approach to clinical trials in sporadic Alzheimer's disease.
Tosun, D., et al.
2024,  
Nature communications
Gene-SGAN: discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering.
Yang, Z., et al.
2024,  
Research square
Alzheimer's disease transcriptional landscape in ex-vivo human microglia.
Roussos, P., et al.
2024,  
Biometrics
Inferring a directed acyclic graph of phenotypes from GWAS summary statistics.
Zilinskas, R., et al.
2024,  
Journal of the American Heart Association
Comparing Cognitive Tests and Smartphone-Based Assessment in 2 US Community-Based Cohorts.
De Anda-Duran, I., et al.
2024,  
Neurobiology of aging
Sex modifies effects of imaging and CSF biomarkers on cognitive and functional outcomes: a study of Alzheimer's disease.
Lee, BN., et al.
2024,  
Biomolecules
Neuroprotective Roles of the Biliverdin Reductase-A/Bilirubin Axis in the Brain.
Paul, BD.
2024,  
Journal of the American Medical Informatics Association : JAMIA
Enabling the clinical application of artificial intelligence in genomics: a perspective of the AMIA Genomics and Translational Bioinformatics Workgroup.
Walton, NA., et al.
2024,  
Research square
Lysophosphatidylcholines are associated with P-tau181 levels in early stages of Alzheimer's Disease.
Vardarajan, B., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Transcriptional risk scores in Alzheimer's disease: From pathology to cognition.
Pyun, J., et al.
2024,  
Alzheimer's research & therapy
miR-129-5p as a biomarker for pathology and cognitive decline in Alzheimer's disease.
Han, S., et al.
2024,  
medRxiv : the preprint server for health sciences
Region-based analysis with functional annotation identifies genes associated with cognitive function in South Asians from India.
Abu-Amara, H., et al.
2024,  
Hypertension (Dallas, Tex. : 1979)
Hypertension Trends and White Matter Brain Injury in the Offspring Framingham Heart Study Cohort.
Petrea, RE., et al.
2024,  
Genome biology
PICALO: principal interaction component analysis for the identification of discrete technical, cell-type, and environmental factors that mediate eQTLs.
Vochteloo, M., et al.
2024,  
eLife
Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model.
Martin Flores, N., et al.
2024,  
medRxiv : the preprint server for health sciences
Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease.
Arnold, M., et al.
2024,  
Biometrics
Accounting for network noise in graph-guided Bayesian modeling of structured high-dimensional data.
Li, W., et al.
2024,  
medRxiv : the preprint server for health sciences
Whole-Genome Sequencing Analysis Reveals New Susceptibility Loci and Structural Variants Associated with Progressive Supranuclear Palsy.
Wang, H., et al.
2024,  
Nature communications
Human whole-exome genotype data for Alzheimer's disease.
Leung, YY., et al.
2024,  
Molecular neurodegeneration
Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease.
Wang, L., et al.
2024,  
Neurobiology of aging
Genetic analyses in multiplex families confirms chromosome 5q35 as a risk locus for Alzheimer's Disease in individuals of African Ancestry.
Nuytemans, K., et al.
2024,  
European journal of neurology
Nonalcoholic fatty liver disease, liver fibrosis, and structural brain imaging: The Cross-Cohort Collaboration.
Weinstein, G., et al.
2024,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
DNA from multiple viral species is associated with Alzheimer's disease risk.
Tejeda, M., et al.
2024,  
Journal of Alzheimer's disease : JAD
Under-Diagnosis of Dementia with Lewy Bodies in Individuals Racialized as Black: Hypotheses Regarding Potential Contributors.
Armstrong, MJ.
2024,  
Journal of Alzheimer's disease : JAD
Using Neuroimaging to Study Cerebral Amyloid Angiopathy and Its Relationship to Alzheimer's Disease.
Wheeler, KV., et al.
2024,  
Dementia and geriatric cognitive disorders
The Association of Neighborhood Socioeconomic Status with Executive Function and Processing Speed in Cognitively Normal Mexican American Elders from the Health and Aging Brains Study: Health Disparities Cohort.
Vintimilla, R., et al.
2024,  
Frontiers in cellular neuroscience
A novel histone deacetylase inhibitor W2A-16 improves the barrier integrity in brain vascular endothelial cells.
Inoue, Y., et al.
2024,  
Journal of Alzheimer's disease : JAD
Effects of Menopause and High Fat Diet on Metabolic Outcomes in a Mouse Model of Alzheimer's Disease.
Abi-Ghanem, C., et al.
2024,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
A deep neural network estimation of brain age is sensitive to cognitive impairment and decline.
Yang, Y., et al.
2024,  
Nature. Mental health
Neuroanatomical dimensions in medication-free individuals with major depressive disorder and treatment response to SSRI antidepressant medications or placebo.
Fu, CHY., et al.
2024,  
KDD : proceedings. International Conference on Knowledge Discovery & Data Mining
Distributed Harmonization: Federated Clustered Batch Effect Adjustment and Generalization.
Hoang, B., et al.
2024,  
Journal of the American Statistical Association
Discovery and inference of a causal network with hidden confounding.
Chen, L., et al.
2024,  
Journal of the American Statistical Association
Nonlinear causal discovery with confounders.
Li, C., et al.
2024,  
Journal of machine learning research : JMLR
Causal Discovery with Generalized Linear Models through Peeling Algorithms.
Wang, M., et al.
2024,  
Frontiers in neurology
Digital neuropsychological measures by defense automated neurocognitive assessment: reference values and clinical correlates.
Ding, H., et al.
2024,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Exploring cognitive progression subtypes in the Framingham Heart Study.
Ding, H., et al.
2024,  
Frontiers in cardiovascular medicine
Association between deep neural network-derived electrocardiographic-age and incident stroke.
Leung, R., et al.
2024,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
SynTwin: A graph-based approach for predicting clinical outcomes using digital twins derived from synthetic patients.
Moore, JH., et al.
2024,  
Machine learning in medical imaging. MLMI (Workshop)
Class-Balanced Deep Learning with Adaptive Vector Scaling Loss for Dementia Stage Detection.
Tong, B., et al.
2024,  
Medical image computing and computer assisted intervention - MICCAI 2023 workshops : ISIC 2023, Care-AI 2023, MedAGI 2023, DeCaF 2023, held in conjunction with MICCAI 2023, Vancouver, BC, Canada, October 8-12, 2023, proceedings
Identifying Shared Neuroanatomic Architecture between Cognitive Traits through Multiscale Morphometric Correlation Analysis.
Wen, Z., et al.
2024,  
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
SABER: Statistical Identification of Loci of Interest in GWAS Summary Statistics using a Bayesian Gaussian Mixture Model.
Kumar, R., et al.
2024,  
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
Cluster Analysis of Cortical Amyloid Burden for Identifying Imaging-driven Subtypes in Mild Cognitive Impairment.
Wu, R., et al.
2024,  
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
PFERM: A Fair Empirical Risk Minimization Approach with Prior Knowledge.
Hou, B., et al.
2023
2023,  
Molecular neurodegeneration
Microglial APOE4: more is less and less is more.
Eskandari-Sedighi, G.
2023,  
Cell stem cell
Toward a CRISPR understanding of gene function in human brain development.
Li, E.
2023,  
Acta neuropathologica communications
Mimicking hypomethylation of FUS requires liquid-liquid phase separation to induce synaptic dysfunctions.
Kim, SC., et al.
2023,  
Brain : a journal of neurology
Speech and language markers of neurodegeneration: a call for global equity.
García, AM., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Profiling and predicting distinct tau progression patterns: An unsupervised data-driven approach to flortaucipir positron emission tomography.
Tosun, D., et al.
2023,  
bioRxiv : the preprint server for biology
Homological landscape of human brain functional sub-circuits.
Duong-Tran, D., et al.
2023,  
medRxiv : the preprint server for health sciences
Five dominant dimensions of brain aging are identified via deep learning: associations with clinical, lifestyle, and genetic measures.
Yang, Z., et al.
2023,  
PLoS genetics
FiMAP: A fast identity-by-descent mapping test for biobank-scale cohorts.
Chen, H., et al.
2023,  
Genetic epidemiology
Inference of causal metabolite networks in the presence of invalid instrumental variables with GWAS summary data.
Chen, S., et al.
2023,  
Scientific reports
Integrated omics analysis of coronary artery calcifications and myocardial infarction: the Framingham Heart Study.
Møller, AL., et al.
2023,  
Advances in neural information processing systems
Fair Canonical Correlation Analysis.
Zhou, Z., et al.
2023,  
Nature communications
High-throughput target trial emulation for Alzheimer's disease drug repurposing with real-world data.
Zang, C., et al.
2023,  
Genes & genomics
A comparative investigation of single nucleotide variant calling for a personal non-Caucasian sequencing sample.
Park, H.
2023,  
The Lancet. Neurology
Pragmatic solutions to reduce the global burden of stroke: a World Stroke Organization-Lancet Neurology Commission.
Feigin, VL.
2023,  
Nature communications
Accelerating African neuroscience to provide an equitable framework using perspectives from West and Southern Africa.
Besharati, S.
2023,  
medRxiv : the preprint server for health sciences
Traumatic brain injury and Alzheimer's Disease biomarkers: A systematic review of findings from amyloid and tau positron emission tomography (PET).
Dybing, KM., et al.
2023,  
Alzheimer's research & therapy
White matter integrity is associated with cognition and amyloid burden in older adult Koreans along the Alzheimer's disease continuum.
Hirschfeld, LR., et al.
2023,  
medRxiv : the preprint server for health sciences
BrainAGE Estimation: Influence of Field Strength, Voxel Size, Race, and Ethnicity.
Dempsey, DA., et al.
2023,  
Proceedings of the National Academy of Sciences of the United States of America
Genomic loci influence patterns of structural covariance in the human brain.
Wen, J., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Large-scale proteome and metabolome analysis of CSF implicates altered glucose and carbon metabolism and succinylcarnitine in Alzheimer's disease.
Panyard, DJ., et al.
2023,  
Nature
Organ aging signatures in the plasma proteome track health and disease.
A comprehensive survey of complex brain network representation.
Tang, H., et al.
2023,  
bioRxiv : the preprint server for biology
Inferring a directed acyclic graph of phenotypes from GWAS summary statistics.
Zilinskas, R., et al.
2023,  
medRxiv : the preprint server for health sciences
Cross-phenotype associations between Alzheimer's Disease and its comorbidities may provide clues to progression.
Moore, A.
2023,  
BMC medical informatics and decision making
Predicting multiple sclerosis severity with multimodal deep neural networks.
Zhang, K., et al.
2023,  
International journal of environmental research and public health
Precision Recruitment and Engagement of Individuals at Risk for Diabetes and Hypertension in Clinical Trials (PREDHICT): A Randomized Trial for an E-Persuasive Mobile Application to Inform Decision Making about Clinical Trials.
Seixas, A., et al.
2023,  
EBioMedicine
Associations of circulating saturated long-chain fatty acids with risk of mild cognitive impairment and Alzheimer's disease in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort.
Fan, L., et al.
2023,  
EBioMedicine
Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data.
Jo, T., et al.
2023,  
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
A Preliminary Study on the Potential Protective Role of the Antioxidative Stress Markers of Cognitive Impairment: Glutathione and Glutathione Reductase.
Park, S., et al.
2023,  
Research square
miR-129-5p as a biomarker for pathology and cognitive decline in Alzheimer's disease.
Han, S., et al.
2023,  
medRxiv : the preprint server for health sciences
A 3'UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated with Increased Risk for FTLD-TDP.
Chemparathy, A., et al.
2023,  
Journal of the American Heart Association
Genome-Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the CETP Gene.
Yu, C., et al.
2023,  
PLoS genetics
Transfer learning with false negative control improves polygenic risk prediction.
Jeng, XJ., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease.
Bai, H., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Alzheimer's disease heterogeneity explained by polygenic risk scores derived from brain transcriptomic profiles.
Chung, J., et al.
2023,  
Neurobiology of aging
An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons.
Cukier, HN., et al.
2023,  
Bioinformatics (Oxford, England)
hipFG: high-throughput harmonization and integration pipeline for functional genomics data.
Cifello, J., et al.
2023,  
Nature communications
INPP5D regulates inflammasome activation in human microglia.
Chou, V., et al.
2023,  
Communications biology
Identification of circulating proteins associated with general cognitive function among middle-aged and older adults.
Tin, A., et al.
2023,  
medRxiv : the preprint server for health sciences
Polygenic burden of short tandem repeat expansions promote risk for Alzheimer's disease.
Guo, MH., et al.
2023,  
medRxiv : the preprint server for health sciences
Research participants' perception of ethical issues in stroke genomics and neurobiobanking research in Africa.
Jegede, A., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Predicting cognitive stage transition using p-tau181, Centiloid, and other measures.
Kwon, HS., et al.
2023,  
Neurobiology of aging
Amyloid and tau pathology are associated with cerebral blood flow in a mixed sample of nondemented older adults with and without vascular risk factors for Alzheimer's disease.
Swinford, CG., et al.
2023,  
Genome medicine
Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning.
Neumann, A., et al.
2023,  
bioRxiv : the preprint server for biology
Effect of altered production and storage of dopamine on development and behavior in C. elegans.
Lee, I., et al.
2023,  
HGG advances
Founder population-specific weights yield improvements in performance of polygenic risk scores for Alzheimer disease in the Midwestern Amish.
Osterman, MD., et al.
2023,  
Genes
Genome-Wide Association Analysis across Endophenotypes in Alzheimer's Disease: Main Effects and Disease Stage-Specific Interactions.
Rosewood, TJ., et al.
2023,  
Research square
Structural Variation Detection and Association Analysis of Whole-Genome-Sequence Data from 16,905 Alzheimer's Diseases Sequencing Project Subjects.
Lee, W., et al.
2023,  
Computational diffusion MRI : MICCAI Workshop
FASSt : Filtering via Symmetric Autoencoder for Spherical Superficial White Matter Tractography.
Li, Y., et al.
2023,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Shape-Aware 3D Small Vessel Segmentation with Local Contrast Guided Attention.
Deng, Z., et al.
2023,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Personalized Patch-based Normality Assessment of Brain Atrophy in Alzheimer's Disease.
Zhang, J.
2023,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Uncovering Heterogeneity in Alzheimer's Disease from Graphical Modeling of the Tau Spatiotemporal Topography.
Yue, J.
2023,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Flow-based Geometric Interpolation of Fiber Orientation Distribution Functions.
Nie, X.
2023,  
Neurology
Retrospective Evaluation of Neuropathologic Proxies of the Minimal Atrophy Subtype Compared With Corticolimbic Alzheimer Disease Subtypes.
Boon, BDC., et al.
2023,  
Scientific reports
Deconvolution reveals cell-type-specific transcriptomic changes in the aging mouse brain.
Ren, Y., et al.
2023,  
Molecular neurodegeneration
Regulation of cortical hyperexcitability in amyotrophic lateral sclerosis: focusing on glial mechanisms.
Xie, M., et al.
2023,  
bioRxiv : the preprint server for biology
A deep neural network estimation of brain age is sensitive to cognitive impairment and decline.
Yang, Y., et al.
2023,  
Annals of neurology
Network Connectivity Alterations across the MAPT Mutation Clinical Spectrum.
Zhang, L., et al.
2023,  
Research square
An ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome.
Snyder, A., et al.
2023,  
Human brain mapping
Style transfer generative adversarial networks to harmonize multisite MRI to a single reference image to avoid overcorrection.
Liu, M., et al.
2023,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Bidirectional Mapping with Contrastive Learning on Multimodal Neuroimaging Data.
Ye, K., et al.
2023,  
bioRxiv : the preprint server for biology
The human microglia responsome: a resource to better understand microglia states in health and disease.
Snijders, GJLJ., et al.
2023,  
bioRxiv : the preprint server for biology
Large-scale causal discovery using interventional data sheds light on the regulatory network architecture of blood traits.
Brown, BC., et al.
2023,  
bioRxiv : the preprint server for biology
A BOOTSTRAP MODEL COMPARISON TEST FOR IDENTIFYING GENES WITH CONTEXT-SPECIFIC PATTERNS OF GENETIC REGULATION.
Malakhov, MM., et al.
2023,  
Clinical epigenetics
Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer's disease at CPT1A locus.
Sarnowski, C., et al.
2023,  
Methods (San Diego, Calif.)
Preference matrix guided sparse canonical correlation analysis for mining brain imaging genetic associations in Alzheimer's disease.
Sha, J., et al.
2023,  
NeuroImage
Brain-wide genome-wide colocalization study for integrating genetics, transcriptomics and brain morphometry in Alzheimer's disease.
Bao, J., et al.
2023,  
medRxiv : the preprint server for health sciences
Characterizing Treatment Non-responders vs. Responders in Completed Alzheimer's Disease Clinical Trials.
Wang, D., et al.
2023,  
Neuron
Blood-based biomarkers for Alzheimer's disease: Current state and future use in a transformed global healthcare landscape.
Hampel, H., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genetic associations with age at dementia onset in the PSEN1 E280A Colombian kindred.
Cochran, JN., et al.
2023,  
Nature medicine
Emerging diagnostics and therapeutics for Alzheimer disease.
Self, WK.
2023,  
APL bioengineering
Direct differentiation of human pluripotent stem cells into vascular network along with supporting mural cells.
Bertucci, T., et al.
2023,  
Nature communications
Single cell multiomic analysis reveals diabetes-associated β-cell heterogeneity driven by HNF1A.
Weng, C., et al.
2023,  
Briefings in bioinformatics
scMultiGAN: cell-specific imputation for single-cell transcriptomes with multiple deep generative adversarial networks.
Wang, T., et al.
2023,  
Scientific reports
Synthetic OCT-A blood vessel maps using fundus images and generative adversarial networks.
Coronado, I., et al.
2023,  
ArXiv
Genetic InfoMax: Exploring Mutual Information Maximization in High-Dimensional Imaging Genetics Studies.
Xie, Y., et al.
2023,  
Journal of the American Heart Association
Evolutionary Action-Machine Learning Model Identifies Candidate Genes Associated With Early-Onset Coronary Artery Disease.
Shapiro, D., et al.
2023,  
Statistics in medicine
Deep causal feature extraction and inference with neuroimaging genetic data.
Yao, Y., et al.
2023,  
Nature reviews. Cardiology
The bidirectional association between atrial fibrillation and myocardial infarction.
Frederiksen, TC., et al.
2023,  
Research square
Adherence type impacts completion rates of frequent mobile cognitive assessments among older adults with and without cognitive impairment.
Christianson, K., et al.
2023,  
ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine
Genetic overlap between Alzheimer's disease and immune-mediated diseases: An atlas of shared genetic determinants and biological convergence.
Fernandes, B., et al.
2023,  
Medical research archives
Effects of Vascular Risk Factors on the Association of Blood-Based Biomarkers with Alzheimer's Disease.
Hoost, SS., et al.
2023,  
BMC bioinformatics
Bulk brain tissue cell-type deconvolution with bias correction for single-nuclei RNA sequencing data using DeTREM.
O'Neill, NK., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
The Early-Onset Alzheimer's Disease Whole-Genome Sequencing Project: Study design and methodology.
Ray, NR., et al.
2023,  
JAMA neurology
Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults.
Walters, S., et al.
2023,  
Aging cell
Sex- and APOE-specific genetic risk factors for late-onset Alzheimer's disease: Evidence from gene-gene interaction of longevity-related loci.
Dato, S., et al.
2023,  
Research square
The impact of blood MCP-1 levels on Alzheimer's disease with genetic variation of UNC5C and NAV3 loci.
Huang, J., et al.
2023,  
medRxiv : the preprint server for health sciences
Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project.
Lee, W., et al.
2023,  
medRxiv : the preprint server for health sciences
Structural Variation Detection and Association Analysis of Whole-Genome-Sequence Data from 16,905 Alzheimer's Diseases Sequencing Project Subjects.
Wang, H., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Ancestry-related differences in chromatin accessibility and gene expression of APOE ε4 are associated with Alzheimer's disease risk.
Celis, K., et al.
2023,  
International journal of geriatric psychiatry
Neuropsychiatric features in a multi-ethnic population with Alzheimer disease and mild cognitive impairment.
Celis, K., et al.
2023,  
Alzheimer's research & therapy
The association of circulating endocannabinoids with neuroimaging and blood biomarkers of neuro-injury.
Vered, S., et al.
2023,  
JAMA network open
Evaluation of Neighborhood-Level Disadvantage and Cognition in Mexican American and Non-Hispanic White Adults 50 Years and Older in the US.
Wong, CG., et al.
2023,  
Molecular & cellular proteomics : MCP
Dissecting Detergent-Insoluble Proteome in Alzheimer's Disease by TMTc-Corrected Quantitative Mass Spectrometry.
Zaman, M., et al.
2023,  
Stem cell research & therapy
APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids.
MidRISH: Unbiased harmonization of rotationally invariant harmonics of the diffusion signal.
Newlin, NR., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Identification of circRNAs linked to Alzheimer's disease and related dementias.
Puri, S., et al.
2023,  
Cell reports
Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions.
Park, J., et al.
2023,  
Proceedings of the National Academy of Sciences of the United States of America
The liquid-to-solid transition of FUS is promoted by the condensate surface.
Shen, Y., et al.
2023,  
Cell reports
Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1.
Lee, H., et al.
2023,  
Nature communications
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases.
Nutma, E., et al.
2023,  
BMJ open
Using community-based geographical information system (GIS) to recruit older Asian Americans in an Alzheimer's disease study.
Lee, H., et al.
2023,  
The Clinical neuropsychologist
Can the Montreal Cognitive Assessment and Mini-Mental State Examination detect cognitive decline in elderly patients with essential tremor?
McGurn, M., et al.
2023,  
Research square
Multimodal nonlinear correlates of behavioural symptoms in frontotemporal dementia.
Zamboni, G., et al.
2023,  
bioRxiv : the preprint server for biology
Disrupted excitation-inhibition balance in cognitively normal individuals at risk of Alzheimer's disease.
Fortel, I., et al.
2023,  
Cell genomics
Multiset correlation and factor analysis enables exploration of multi-omics data.
Brown, BC., et al.
2023,  
Bioinformatics (Oxford, England)
ShinyBioHEAT: an interactive shiny app to identify phenotype driver genes in E.coli and B.subtilis.
Wang, C., et al.
2023,  
Human molecular genetics
Integrating GWAS summary statistics, individual-level genotypic and omic data to enhance the performance for large-scale trait imputation.
Ren, J., et al.
2023,  
Journal of econometrics
Distribution-Invariant Differential Privacy.
Bi, X.
2023,  
medRxiv : the preprint server for health sciences
AORTA Gene: Polygenic prediction improves detection of thoracic aortic aneurysm.
Pirruccello, JP., et al.
2023,  
CPT: pharmacometrics & systems pharmacology
Knowledge graph aids comprehensive explanation of drug and chemical toxicity.
Hao, Y., et al.
2023,  
medRxiv : the preprint server for health sciences
Improving Genetic Association Studies with a Novel Methodology that Unveils the Hidden Complexity of All-Cause Heart Failure.
Gregg, JT., et al.
2023,  
Proceedings of machine learning research
Fairness-Aware Class Imbalanced Learning on Multiple Subgroups.
Tarzanagh, DA., et al.
2023,  
medRxiv : the preprint server for health sciences
Extended genome-wide association study employing the African Genome Resources Panel identifies novel susceptibility loci for Alzheimer's Disease in individuals of African ancestry.
Ray, NR., et al.
2023,  
medRxiv : the preprint server for health sciences
Risk of Alzheimer's Disease is Associated with Longitudinal Changes in Plasma Biomarkers in the Multiethnic Washington Heights, Inwood Columbia Aging Project Cohort.
Gu, Y., et al.
2023,  
medRxiv : the preprint server for health sciences
Lysophosphatidylcholines are associated with P-tau181 levels in early stages of Alzheimer's Disease.
International journal of stroke : official journal of the International Stroke Society
Pleiotropy analysis between lobar intracerebral hemorrhage and CSF β-amyloid highlights new and established associations.
Marini, S., et al.
2023,  
Journal of neuropathology and experimental neurology
LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry.
Katsumata, Y., et al.
2023,  
Journal of clinical medicine
Genetics of Alzheimer's Disease in the African American Population.
Logue, MW., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genome-wide methylomic regulation of multiscale gene networks in Alzheimer's disease.
Wang, E., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Obesity impacts the expression of Alzheimer's disease-related genes: The Framingham Heart Study.
Charisis, S., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Placental growth factor as a sensitive biomarker for vascular cognitive impairment.
Hinman, JD., et al.
2023,  
Scientific reports
Cerebral small vessel disease burden is associated with decreased abundance of gut Barnesiella intestinihominis bacterium in the Framingham Heart Study.
Fongang, B., et al.
2023,  
Behavior genetics
A Varying Coefficient Model to Jointly Test Genetic and Gene-Environment Interaction Effects.
Zhou, Z., et al.
2023,  
Molecular neurodegeneration
Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease.
Inoue, Y., et al.
2023,  
bioRxiv : the preprint server for biology
Improved Protocol for Reproducible Human Cortical Organoids Reveals Early Alterations in Metabolism with MAPT Mutations.
Bertucci, T., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Prediction of neuropathologic lesions from clinical data.
Phongpreecha, T., et al.
2023,  
Journal of neurology, neurosurgery, and psychiatry
Plasma inflammation for predicting phenotypic conversion and clinical progression of autosomal dominant frontotemporal lobar degeneration.
Asken, BM., et al.
2023,  
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Predictive Modeling Of Alzheimer's Disease Prognosis Using Anatomical & Diffusion MRI.
Goel, N., et al.
2023,  
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Efficiently Training Vision Transformers on Structural MRI Scans for Alzheimer's Disease Detection.
Dhinagar, NJ., et al.
2023,  
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Evaluating Fiber Orientation Dispersion Measures Computed From Single-Shell Diffusion MRI.
Villalon-Reina, JE., et al.
2023,  
Acta neuropathologica
Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals OTUD4 in shared dysregulated signatures across pathological subtypes.
Fodder, K., et al.
2023,  
HGG advances
Using GWAS summary data to impute traits for genotyped individuals.
Ren, J., et al.
2023,  
Circulation. Cardiovascular quality and outcomes
Association Between Electrocardiographic Age and Cardiovascular Events in Community Settings: The Framingham Heart Study.
Brant, LCC., et al.
2023,  
Proceedings of the National Academy of Sciences of the United States of America
Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease.
Cazzaro, S., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
A call for clinical trial globalization in Alzheimer's disease and related dementia.
Llibre-Guerra, JJ., et al.
2023,  
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Association of Central Auditory Processing Dysfunction With Preclinical Alzheimer's Disease.
Byun, MS., et al.
2023,  
NeuroImage
Image harmonization: A review of statistical and deep learning methods for removing batch effects and evaluation metrics for effective harmonization.
Hu, F., et al.
2023,  
Human molecular genetics
Genetic architecture of plasma Alzheimer disease biomarkers.
Bradley, J., et al.
2023,  
Science translational medicine
Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease.
Sung, YJ., et al.
2023,  
NPJ Parkinson's disease
Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson's disease.
Phillips, B., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Prevalence of dementia in India: National and state estimates from a nationwide study.
Lee, J., et al.
2023,  
Nature human behaviour
Identifying modifiable factors and their joint effect on dementia risk in the UK Biobank.
Zhang, Y., et al.
2023,  
NPJ Regenerative medicine
Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer's disease.
Siddiqui, T., et al.
2023,  
Neurobiology of aging
Inflammatory biomarkers and MRI visible perivascular spaces: The Framingham Heart Study.
Ekenze, O., et al.
2023,  
Science translational medicine
Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life.
Walker, KA., et al.
2023,  
Nature medicine
Clonal hematopoiesis is associated with protection from Alzheimer's disease.
Bouzid, H., et al.
2023,  
HGG advances
Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations.
Horimoto, ARVR., et al.
2023,  
medRxiv : the preprint server for health sciences
APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's Disease pathology.
Chemparathy, A., et al.
2023,  
Trends in neurosciences
Moving beyond amyloid and tau to capture the biological heterogeneity of Alzheimer's disease.
Young-Pearse, TL., et al.
2023,  
British journal of cancer
Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state.
Yu, W., et al.
2023,  
Journal of biomedical informatics
HLA amino acid Mismatch-Based risk stratification of kidney allograft failure using a novel Machine learning algorithm.
Dasariraju, S., et al.
2023,  
NPJ digital medicine
A flexible symbolic regression method for constructing interpretable clinical prediction models.
La Cava, WG., et al.
2023,  
British journal of pharmacology
Hydrogen sulfide signalling in neurodegenerative diseases.
Tripathi, SJ., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Social enrichment on the job: Complex work with people improves episodic memory, promotes brain reserve, and reduces the risk of dementia.
Coleman, ME., et al.
2023,  
Aging and disease
Serum Adiponectin and In Vivo Brain Amyloid Deposition in Cognitively Normal Older Adults: A Cohort Study.
Kim, JW., et al.
2023,  
Alzheimer's research & therapy
Body mass index and two-year change of in vivo Alzheimer's disease pathologies in cognitively normal older adults.
Lee, S., et al.
2023,  
Research square
Unique genetic architecture of CSF and brain metabolites pinpoints the novel targets for the traits of human wellness.
Wang, C., et al.
2023,  
Research square
Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer's disease.
Cruchaga, C., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
APOE and immunity: Research highlights.
Kloske, CM., et al.
2023,  
Neurobiology of aging
Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease.
Seto, M., et al.
2023,  
Scientific reports
Modeling of mitochondrial genetic polymorphisms reveals induction of heteroplasmy by pleiotropic disease locus 10398A>G.
Smullen, M., et al.
2023,  
Molecular neurodegeneration
A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores.
Kang, M., et al.
2023,  
Acta neuropathologica
Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation.
Filipello, F., et al.
2023,  
Molecular neurodegeneration
Sex specific molecular networks and key drivers of Alzheimer's disease.
Guo, L., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.
Rajabli, F., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
AD and non-AD mediators of the pathway between the APOE genotype and cognition.
Nichols, E., et al.
2023,  
STAR protocols
Standardized immunoprecipitation protocol for efficient isolation of native apolipoprotein E particles utilizing HJ15.4 monoclonal antibody.
O'Leary, J., et al.
2023,  
Medicine
The SERPINA5 coding variant E228Q does not contribute to clinicopathologic characteristics in Alzheimer's disease: A cross-sectional study.
Matchett, BJ., et al.
2023,  
The Journal of cell biology
Autolysosomal exocytosis of lipids protect neurons from ferroptosis.
Ralhan, I., et al.
2023,  
Brain : a journal of neurology
The pathotome and precision health.
Younes, K.
2023,  
Cell stem cell
Advancing cell therapy for neurodegenerative diseases.
Temple, S.
2023,  
Biology of sex differences
Sex differences in the effects of high fat diet on underlying neuropathology in a mouse model of VCID.
Abi-Ghanem, C., et al.
2023,  
Biology of sex differences
Menopause causes metabolic and cognitive impairments in a chronic cerebral hypoperfusion model of vascular contributions to cognitive impairment and dementia.
Gannon, OJ., et al.
2023,  
Neuropsychology
Harmonizing the preclinical Alzheimer cognitive composite for multicohort studies.
Hampton, OL., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Association of spermidine plasma levels with brain aging in a population-based study.
Wortha, SM., et al.
2023,  
bioRxiv : the preprint server for biology
Leveraging longitudinal diffusion MRI data to quantify differences in white matter microstructural decline in normal and abnormal aging.
Archer, DB., et al.
2023,  
Research square
Accumulation of m6A exhibits stronger correlation with MAPT than β-amyloid pathology in an APPNL-G-F/MAPTP301S mouse model of Alzheimer's disease
2023,  
medRxiv : the preprint server for health sciences
Single-cell RNA sequencing data reveals rewiring of transcriptional relationships in Alzheimer's Disease associated with risk variants.
Bouland, GA., et al.
2023,  
Journal of geriatric psychiatry and neurology
Demographic and Symptom Correlates of Initial Idiopathic Psychiatric Diagnosis in Frontotemporal Dementia.
Sejourne, C., et al.
2023,  
Biological psychiatry
Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood.
Ge, Y., et al.
2023,  
JAMA neurology
Evaluation of Plasma Phosphorylated Tau217 for Differentiation Between Alzheimer Disease and Frontotemporal Lobar Degeneration Subtypes Among Patients With Corticobasal Syndrome.
VandeVrede, L., et al.
2023,  
Neuropsychology
Cognitive domain harmonization and cocalibration in studies of older adults.
Mukherjee, S., et al.
2023,  
Cancers
Genetic Variants Associated with Longitudinal Cognitive Performance in Older Breast Cancer Patients and Controls.
Nudelman, K., et al.
2023,  
Nature communications
Functional variants identify sex-specific genes and pathways in Alzheimer's Disease.
Bourquard, T., et al.
2023,  
PLoS genetics
Combining Mendelian randomization and network deconvolution for inference of causal networks with GWAS summary data.
Lin, Z., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Population-based discovery and Mendelian randomization analysis identify telmisartan as a candidate medicine for Alzheimer's disease in African Americans.
Zhang, P., et al.
2023,  
Antioxidants (Basel, Switzerland)
Protective Roles of Hydrogen Sulfide in Alzheimer's Disease and Traumatic Brain Injury.
Paul, BD.
2023,  
Cell reports methods
Longitudinal in vivo monitoring of axonal degeneration after brain injury.
Chornyy, S., et al.
2023,  
Biological psychiatry
Integrative Co-methylation Network Analysis Identifies Novel DNA Methylation Signatures and Their Target Genes in Alzheimer's Disease.
Kim, JP., et al.
2023,  
Annals of neurology
Aberrant GAP43 Gene Expression Is Alzheimer Disease Pathology-Specific.
Pyun, J., et al.
2023,  
Experimental & molecular medicine
Sex differences in the progression of glucose metabolism dysfunction in Alzheimer's disease.
Park, J., et al.
2023,  
Neuropsychology
Linking self-perceived cognitive functioning questionnaires using item response theory: The subjective cognitive decline initiative.
Rabin, LA., et al.
2023,  
bioRxiv : the preprint server for biology
Harmonization of CSF and imaging biomarkers for Alzheimer's disease biomarkers: need and practical applications for genetics studies and preclinical classification.
Timsina, J., et al.
2023,  
The journals of gerontology. Series A, Biological sciences and medical sciences
Polygenic Risk Scores for Alzheimer's Disease and General Cognitive Function Are Associated With Measures of Cognition in Older South Asians.
Zhao, W., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Measurement differences in the assessment of functional limitations for cognitive impairment classification across geographic locations.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains.
Novotny, BC., et al.
2023,  
Cerebral cortex (New York, N.Y. : 1991)
Heritability of cognitive abilities and regional brain structures in middle-aged to elderly East Asians.
Lee, Y., et al.
2023,  
Translational psychiatry
Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study.
Pan, M., et al.
2023,  
Nature reviews. Neurology
A global view of the genetic basis of Alzheimer disease.
Reitz, C., et al.
2023,  
Neurology
Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts.
Zhang, Y., et al.
2023,  
Stroke
Vascular Risk Predicts Plasma Amyloid β 42/40 Through Cerebral Amyloid Burden in Apolipoprotein E ε4 Carriers.
Sapkota, S., et al.
2023,  
Annals of neurology
APOE2 Exacerbates TDP-43 Related Toxicity in the Absence of Alzheimer Pathology.
Meneses, AD., et al.
2023,  
Journal of lipid research
Regulation of astrocyte lipid metabolism and ApoE secretionby the microglial oxysterol, 25-hydroxycholesterol.
Cashikar, AG., et al.
2023,  
JCI insight
LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4.
Oue, H., et al.
2023,  
Neurobiology of disease
The role of innate lymphocytes in regulating brain and cognitive function.
Si, Y., et al.
2023,  
NeuroImage
Deep neural network heatmaps capture Alzheimer's disease patterns reported in a large meta-analysis of neuroimaging studies.
Wang, D., et al.
2023,  
Alzheimer's research & therapy
Higher performance for women than men in MRI-based Alzheimer's disease detection.
Klingenberg, M., et al.
2023,  
JAMA network open
Assessment of Risk Factors and Clinical Importance of Enlarged Perivascular Spaces by Whole-Brain Investigation in the Multi-Ethnic Study of Atherosclerosis.
Charisis, S., et al.
2023,  
bioRxiv : the preprint server for biology
A benchmark study on current GWAS models in admixed populations.
Yang, Z., et al.
2023,  
Brain : a journal of neurology
Brain functional connectivity mirrors genetic pleiotropy in psychiatric conditions.
Moreau, CA., et al.
2023,  
NeuroImage
Applications of generative adversarial networks in neuroimaging and clinical neuroscience.
Wang, R., et al.
2023,  
NeuroImage
Multiscale functional connectivity patterns of the aging brain learned from harmonized rsfMRI data of the multi-cohort iSTAGING study.
Zhou, Z., et al.
2023,  
The Journal of biological chemistry
Coevolutionary signals in metabotropic glutamate receptors capture residue contacts and long-range functional interactions.
Huh, E., et al.
2023,  
Human molecular genetics
MATS: a novel multi-ancestry transcriptome-wide association study to account for heterogeneity in the effects of cis-regulated gene expression on complex traits.
Knutson, KA.
2023,  
American journal of human genetics
Robust multivariable Mendelian randomization based on constrained maximum likelihood.
Lin, Z., et al.
2023,  
Scientific reports
Sex-specific differences in the genetic and environmental effects on cardiac phenotypic variation assessed by echocardiography.
Lin, H., et al.
2023,  
American journal of human genetics
Evidence of epistasis in regions of long-range linkage disequilibrium across five complex diseases in the UK Biobank and eMERGE datasets.
Singhal, P., et al.
2023,  
Biomedicines
Increased Risk of Aging-Related Neurodegenerative Disease after Traumatic Brain Injury.
Barker, S., et al.
2023,  
JAMA network open
Evaluation of Plasma Biomarkers for A/T/N Classification of Alzheimer Disease Among Adults of Caribbean Hispanic Ethnicity.
Honig, LS., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Differential diagnosis of amnestic dementia patients based on an FDG-PET signature of autopsy-confirmed LATE-NC.
Grothe, MJ., et al.
2023,  
Annals of behavioral medicine : a publication of the Society of Behavioral Medicine
An Examination of the Longitudinal Relationship Between Cognitive Function and Physical Activity Among Older Breast Cancer Survivors in the Thinking and Living With Cancer Study.
Tometich, DB., et al.
2023,  
Brain imaging and behavior
Altered cerebral blood flow in older adults with Alzheimer's disease: a systematic review.
White matter integrity is associated with cognition and amyloid burden in older adult Koreans along the Alzheimer's disease continuum.
Hirschfeld, LR., et al.
2023,  
iScience
Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer's and coronary disease pathways.
Wang, L., et al.
2023,  
Acta neuropathologica communications
Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease.
Ali, M., et al.
2023,  
EBioMedicine
The complex genetic architecture of Alzheimer's disease: novel insights and future directions.
Andrews, SJ., et al.
2023,  
International journal of geriatric psychiatry
Psychometric approaches to defining cognitive phenotypes in the Old Order Amish.
Zaman, A., et al.
2023,  
Nature genetics
Adjusting for common variant polygenic scores improves yield in rare variant association analyses.
Jurgens, SJ., et al.
2023,  
Genes
Interaction between KLOTHO-VS Heterozygosity and APOE ε4 Allele Predicts Rate of Cognitive Decline in Late-Onset Alzheimer's Disease.
Chen, XR., et al.
2023,  
Communications medicine
Deep learning-based polygenic risk analysis for Alzheimer's disease prediction.
Zhou, X., et al.
2023,  
Nature communications
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers.
Brase, L., et al.
2023,  
bioRxiv : the preprint server for biology
hipFG: High-throughput harmonization and integration pipeline for functional genomics data.
Cifello, J., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Plasma metabolites associated with cognitive function across race/ethnicities affirming the importance of healthy nutrition.
Granot-Hershkovitz, E., et al.
2023,  
European journal of epidemiology
Serum neurofilament light chain, brain infarcts, and the risk of stroke: a prospective population-based cohort study.
Dhana, A., et al.
2023,  
Nature medicine
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease.
Duperron, M., et al.
2023,  
Molecular psychiatry
African ancestry GWAS of dementia in a large military cohort identifies significant risk loci.
Sherva, R., et al.
2023,  
medRxiv : the preprint server for health sciences
Epistatic Features and Machine Learning Improve Alzheimer's Risk Prediction Over Polygenic Risk Scores.
Hermes, S., et al.
2023,  
Nature communications
OTTERS: a powerful TWAS framework leveraging summary-level reference data.
Dai, Q., et al.
2023,  
Nature aging
Human striatal glia differentially contribute to AD- and PD-specific neurodegeneration.
Xu, J., et al.
2023,  
Annals of neurology
Alzheimer's Disease Genetic Risk, Cognition, and Brain Aging in Midlife.
Brenowitz, WD., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Phosphorylated tau sites that are elevated in Alzheimer's disease fluid biomarkers are visualized in early neurofibrillary tangle maturity levels in the post mortem brain.
Moloney, CM., et al.
2023,  
STAR protocols
An assay to evaluate the capacity of cholesterol acceptors using BODIPY-cholesterol in cells.
Raulin, A., et al.
2023,  
Molecular neurodegeneration
hiPSC-based models to decipher the contribution of human astrocytes to Alzheimer's disease and potential therapeutics.
Tcw, J.
2023,  
JAMA network open
Association of Intensive vs Standard Blood Pressure Control With Regional Changes in Cerebral Small Vessel Disease Biomarkers: Post Hoc Secondary Analysis of the SPRINT MIND Randomized Clinical Trial.
Rashid, T., et al.
2023,  
bioRxiv : the preprint server for biology
Accumulation of m6A exhibits stronger correlation with MAPT than β-amyloid pathology in an APPNL-G-F/MAPTP301S mouse model of Alzheimer's disease
2023,  
medRxiv : the preprint server for health sciences
A single-nucleus transcriptome-wide association study implicates novel genes in depression pathogenesis.
Zeng, L., et al.
2023,  
JMIR public health and surveillance
The Effect of Activity Participation in Middle-Aged and Older People on the Trajectory of Depression in Later Life: National Cohort Study.
Gao, Y., et al.
2023,  
Trends in neurosciences
The foundation and architecture of precision medicine in neurology and psychiatry.
Hampel, H., et al.
2023,  
Neuroimage. Reports
Deep Learning Based Detection of Enlarged Perivascular Spaces on Brain MRI.
Rashid, T., et al.
2023,  
Genes
Deep Learning-Based Feature Extraction with MRI Data in Neuroimaging Genetics for Alzheimer's Disease.
Chakraborty, D., et al.
2023,  
Journal of medical Internet research
Step Count, Self-reported Physical Activity, and Predicted 5-Year Risk of Atrial Fibrillation: Cross-sectional Analysis.
Shapira-Daniels, A., et al.
2023,  
Briefings in bioinformatics
Integrative analysis of multi-omics and imaging data with incorporation of biological information via structural Bayesian factor analysis.
Bao, J., et al.
2023,  
Alzheimer's research & therapy
Alzheimer's disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals.
Pettigrew, C., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Differences in the measurement of cognition for the assessment of dementia across geographic contexts: Recommendations for cross-national research.
Nichols, E., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women.
Chung, J., et al.
2023,  
Biochemistry
Evaluation of a Pooling Chemoproteomics Strategy with an FDA-Approved Drug Library.
Sun, H., et al.
2023,  
Proteomics
JUMPptm: Integrated software for sensitive identification of post-translational modifications and its application in Alzheimer's disease study.
Poudel, S., et al.
2023,  
Proceedings of the National Academy of Sciences of the United States of America
Apolipoprotein E4 has extensive conformational heterogeneity in lipid-free and lipid-bound forms.
Stuchell-Brereton, MD., et al.
2023,  
Science advances
Chaperoning of specific tau structure by immunophilin FKBP12 regulates the neuronal resilience to extracellular stress.
Jiang, L., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
The small HDL particle hypothesis of Alzheimer's disease.
Martinez, AE., et al.
2023,  
IEEE transactions on medical imaging
BrainGB: A Benchmark for Brain Network Analysis With Graph Neural Networks.
Cui, H., et al.
2023,  
Human brain mapping
Benchmarking the generalizability of brain age models: Challenges posed by scanner variance and prediction bias.
Jirsaraie, RJ., et al.
2023,  
Proceedings of the National Academy of Sciences of the United States of America
Bias in machine learning models can be significantly mitigated by careful training: Evidence from neuroimaging studies.
Wang, R., et al.
2023,  
Bioinformatics (Oxford, England)
LDmat: efficiently queryable compression of linkage disequilibrium matrices.
Weiner, RJ., et al.
2023,  
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference.
Schnabel, RB., et al.
2023,  
Computational toxicology (Amsterdam, Netherlands)
Exploring genetic influences on adverse outcome pathways using heuristic simulation and graph data science.
Romano, JD., et al.
2023,  
CNS neuroscience & therapeutics
Enlarged perivascular spaces are associated with decreased brain tau deposition.
Kang, KM., et al.
2023,  
Genome medicine
TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation.
Moutinho, M., et al.
2023,  
bioRxiv : the preprint server for biology
BHLHE40/41 regulate macrophage/microglia responses associated with Alzheimer's disease and other disorders of lipid-rich tissues.
Podlesny-Drabiniok, A., et al.
2023,  
BMC public health
Cohort Profile: Real-Time Insights of COVID-19 in India (RTI COVID-India).
Banerjee, J., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genetic variants in the SHISA6 gene are associated with delayed cognitive impairment in two family datasets.
Ramos, J., et al.
2023,  
JAMA
Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease.
Le Guen, Y., et al.
2023,  
Genome biology
FixItFelix: improving genomic analysis by fixing reference errors.
Behera, S., et al.
2023,  
Molecular psychiatry
Neuroimmune transcriptome changes in patient brains of psychiatric and neurological disorders.
Chen, Y., et al.
2023,  
Stroke
Comparative Effectiveness and Safety of Seizure Prophylaxis Among Adults After Acute Ischemic Stroke.
Moura, LMVR., et al.
2023,  
Journal of clinical epidemiology
No short-term mortality from benzodiazepine use post-acute ischemic stroke after accounting for bias.
Moura, LMVR., et al.
2023,  
Nature communications
Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders.
Cui, Y., et al.
2023,  
medRxiv : the preprint server for health sciences
MS4A4A modifies the risk of Alzheimer disease by regulating lipid metabolism and immune response in a unique microglia state.
You, S., et al.
2023,  
Brain : a journal of neurology
Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI.
Yang, Y., et al.
2023,  
Medicine and science in sports and exercise
Association of Accelerometer-Measured Physical Activity and Sedentary Time with Epigenetic Markers of Aging.
Spartano, NL., et al.
2023,  
medRxiv : the preprint server for health sciences
Chromosome 10q24.32 Variants Associate with Brain Arterial Diameters in Diverse Populations: A Genome-Wide Association Study.
Liu, M., et al.
2023,  
Molecules (Basel, Switzerland)
Evolutionary Couplings and Molecular Dynamic Simulations Highlight Details of GPCRs Heterodimers' Interfaces.
Nchourupouo, KWT., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Higher Dietary Inflammatory Index scores are associated with brain MRI markers of brain aging: Results from the Framingham Heart Study Offspring cohort.
Melo Van Lent, D., et al.
2023,  
Neurobiology of aging
Investigation of the independent role of a rare APOE variant (L28P; APOE*4Pittsburgh) in late-onset Alzheimer disease.
Fan, K., et al.
2023,  
Journal of sleep disorders & therapy
Strategies to Engage Blacks in Sleep Medicine: Lessons Learned from Three Studies Applying Community-Based Participatory Research Principles.
Rogers, A., et al.
2023,  
Journal of Alzheimer's disease : JAD
Biomarkers and Risk Assessment of Alzheimer's Disease in Low- and Middle-Income Countries.
Adewale, BA., et al.
2023,  
Journal of Alzheimer's disease : JAD
Low Ankle-Brachial Index Relates to Alzheimer-Signature Cerebral Glucose Metabolism in Cognitively Impaired Older Adults.
Moon, SW., et al.
2023,  
Alzheimer's & dementia (New York, N. Y.)
Accelerating diversity in Alzheimer's disease research by partnering with a community advisory board.
Pena-Garcia, A., et al.
2023,  
Journal of Alzheimer's disease : JAD
Development of a Cognitive Composite for Preclinical Alzheimer's Disease in Korean Older Adults.
Kim, M., et al.
2023,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Predicting amyloid PET positivity using plasma p-tau181 and other blood-based biomarkers.
Kwon, HS., et al.
2023,  
Journal of Alzheimer's disease : JAD
Reliability and Validity of Self-Reported Vascular Risk Factors: Hypertension, Diabetes, and Heart Disease, in a Multi-Ethnic Community Based Study of Aging and Dementia.
Lee, AJ., et al.
2023,  
Journal of Alzheimer's disease : JAD
Linking Air Pollution Exposure to Blood-Based Metabolic Features in a Community-Based Aging Cohort with and without Dementia.
Kalia, V., et al.
2023,  
Neuroepidemiology
Estimating the Prevalence of Dementia in India Using a Semi-Supervised Machine Learning Approach.
Jin, H., et al.
2023,  
Journal of Parkinson's disease
Sleep Disorders in Early-Onset Parkinsonism: A Population-Based Study.
McCarter, SJ., et al.
2023,  
Journal of Alzheimer's disease : JAD
Visit-to-Visit Blood Pressure Variability and Cognitive Decline in Apolipoprotein ɛ4 Carriers versus Apolipoprotein ɛ3 Homozygotes.
Sible, IJ.
2023,  
Journal of Alzheimer's disease : JAD
Polygenic Liability to Alzheimer's Disease Is Associated with a Wide Range of Chronic Diseases: A Cohort Study of 312,305 Participants.
Wu, B., et al.
2023,  
Alzheimer's & dementia (New York, N. Y.)
Altered gene expression in excitatory neurons is associated with Alzheimer's disease and its higher incidence in women.
Garcia, AX., et al.
2023,  
Frontiers in aging neuroscience
Effects of copy number variations on longevity in late-onset Alzheimer's disease patients: insights from a causality network analysis.
Hao, Y., et al.
2023,  
Journal of Alzheimer's disease : JAD
Association of Physical Inactivity with MRI Markers of Brain Aging: Assessing Mediation by Cardiometabolic and Epigenetic Factors.
Spartano, NL., et al.
2023,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Early-onset Alzheimer's disease explained by polygenic risk of late-onset disease?
Mantyh, WG., et al.
2023,  
Molecular neurobiology
Suppression of Wnt/β-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer's Disease.
Macyczko, JR., et al.
2023,  
Annual review of pathology
Genetics and Pathogenesis of Parkinson's Syndrome.
Ye, H., et al.
2023,  
Human molecular genetics
Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson's disease genes.
Li, J., et al.
2023,  
Neurology
Determinants of Perivascular Spaces in the General Population: A Pooled Cohort Analysis of Individual Participant Data.
Evans, TE., et al.
2023,  
Molecular neurodegeneration
APOE effects on regional tau in preclinical Alzheimer's disease.
Young, CB., et al.
2023,  
JMIR public health and surveillance
Social Support and Technology Use and Their Association With Mental and Physical Health During the COVID-19 Pandemic Among Asian Americans: The COMPASS Cross-sectional Study.
Park, LG., et al.
2023,  
JAMA neurology
Association of Physical Activity With Neurofilament Light Chain Trajectories in Autosomal Dominant Frontotemporal Lobar Degeneration Variant Carriers.
Casaletto, KB., et al.
2023,  
Biological psychiatry
Genetic Heterogeneity Shapes Brain Connectivity in Psychiatry.
Moreau, CA., et al.
2023,  
Medical image analysis
Signed graph representation learning for functional-to-structural brain network mapping.
Tang, H., et al.
2023,  
Proceedings of the National Academy of Sciences of the United States of America
Anatomically interpretable deep learning of brain age captures domain-specific cognitive impairment.
Yin, C., et al.
2023,  
BMC psychiatry
AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale.
Fu, CHY., et al.
2023,  
Nature neuroscience
Integrative transcriptomic analysis of the amyotrophic lateral sclerosis spinal cord implicates glial activation and suggests new risk genes.
Humphrey, J., et al.
2023,  
Journal of medical Internet research
Increasing Engagement in the Electronic Framingham Heart Study: Factorial Randomized Controlled Trial.
Trinquart, L., et al.
2023,  
Nature biotechnology
A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.
Zhou, Y., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Midlife lipid and glucose levels are associated with Alzheimer's disease.
Zhang, X., et al.
2023,  
Neurobiology of disease
The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms.
Felsky, D., et al.
2023,  
Scientific data
Deep phenotyping and genomic data from a nationally representative study on dementia in India.
Lee, J., et al.
2023,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Identification of the Aβ37/42 peptide ratio in CSF as an improved Aβ biomarker for Alzheimer's disease.
Liu, L., et al.
2023,  
Neuron
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.
Gratuze, M., et al.
2023,  
Molecular neurodegeneration
Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer's disease related proteins.
Oatman, SR., et al.
2023,  
Scientific reports
Explainable machine learning aggregates polygenic risk scores and electronic health records for Alzheimer's disease prediction.
Gao, XR., et al.
2023,  
Alzheimer's research & therapy
A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice.
Barendrecht, S., et al.
2023,  
Computational diffusion MRI : MICCAI Workshop
Automated Mapping of Residual Distortion Severity in Diffusion MRI.
Huang, S., et al.
2023,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Association of cardiovascular risk factors and blood biomarkers with cognition: The HABS-HD study.
Jiang, X., et al.
2023,  
The journal of prevention of Alzheimer's disease
Understanding Online Registry Facilitators and Barriers Experienced by Black Brain Health Registry Participants: The Community Engaged Digital Alzheimer's Research (CEDAR) Study.
Ashford, MT., et al.
2023,  
Gerontology & geriatric medicine
Association of Area Deprivation Index and hypertension, diabetes, dyslipidemia, and Obesity: A Cross-Sectional Study of the HABS-HD Cohort.
Vintimilla, R., et al.
2023,  
Alzheimer's & dementia (Amsterdam, Netherlands)
A fresh look at the multi-level social determinants of disparities in Alzheimer's disease and related dementias.
Britton, GB.
2023,  
The journal of prevention of Alzheimer's disease
The Community Engaged Digital Alzheimer's Research (CEDAR) Study: A Digital Intervention to Increase Research Participation of Black American Participants in the Brain Health Registry.
Mindt, MR., et al.
2023,  
Journal of Alzheimer's disease : JAD
Comorbidities Incorporated to Improve Prediction for Prevalent Mild Cognitive Impairment and Alzheimer's Disease in the HABS-HD Study.
Zhang, F., et al.
2023,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Bilingual neurocognitive resiliency, vulnerability, and Alzheimer's disease biomarker correlates in Latino older adults enrolled in the Health and Aging Brain Study - Health Disparities (HABS-HD).
Grasso, SM., et al.
2023,  
Journal of Alzheimer's disease : JAD
Hypermethylation at CREBBP Is Associated with Cognitive Impairment in a Mexican American Cohort.
Abraham Daniel, A., et al.
2023,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Top Alzheimer's disease risk allele frequencies differ in HABS-HD Mexican- versus Non-Hispanic White Americans.
Housini, M., et al.
2023,  
Frontiers in neuroscience
Understanding the molecular basis of resilience to Alzheimer's disease.
Montine, KS., et al.
2023,  
Frontiers in molecular biosciences
Conserved gene signatures shared among MAPT mutations reveal defects in calcium signaling.
Minaya, MA., et al.
2023,  
Neuroendocrinology
Changes in Corticotropin-Releasing Factor Receptor Type 1, Co-Expression with Tyrosine Hydroxylase and Oxytocin Neurons, and Anxiety-Like Behaviors across the Postpartum Period in Mice.
De Guzman, RM., et al.
2023,  
Alzheimer's & dementia (Amsterdam, Netherlands)
White matter microstructural metrics are sensitively associated with clinical staging in Alzheimer's disease.
Yang, Y., et al.
2023,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Leveraging longitudinal diffusion MRI data to quantify differences in white matter microstructural decline in normal and abnormal aging.
Archer, DB., et al.
2023,  
Journal of Alzheimer's disease : JAD
Postmortem Brain Imaging in Alzheimer's Disease and Related Dementias: The South Texas Alzheimer's Disease Research Center Repository.
Li, K., et al.
2023,  
Clinical gerontologist
A scoping review of dementia caregiving for Korean Americans and recommendations for future research.
Ta Park, VM., et al.
2023,  
Alzheimer's & dementia (New York, N. Y.)
The development of the Cognitive Assessment for Tagalog Speakers (CATS): A culturally and linguistically tailored test battery for Filipino Americans.
de Leon, J., et al.
2023,  
Brain communications
Uncovering spatiotemporal patterns of atrophy in progressive supranuclear palsy using unsupervised machine learning.
Scotton, WJ., et al.
2023,  
Frontiers in neurology
Case report: TMEM106B haplotype alters penetrance of GRN mutation in frontotemporal dementia family.
Perneel, J., et al.
2023,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research.
Taylor, JC., et al.
2023,  
Journal of Alzheimer's disease : JAD
Improved Prediction of Amyloid-β and Tau Burden Using Hippocampal Surface Multivariate Morphometry Statistics and Sparse Coding.
Wu, J., et al.
2023,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Polygenic resilience score may be sensitive to preclinical Alzheimer's disease changes.
Eissman, JM., et al.
2023,  
Journal of Alzheimer's disease : JAD
A Surface-Based Federated Chow Test Model for Integrating APOE Status, Tau Deposition Measure, and Hippocampal Surface Morphometry.
Wu, J., et al.
2023,  
Journal of Alzheimer's disease : JAD
Disrupted Excitation-Inhibition Balance in Cognitively Normal Individuals at Risk of Alzheimer's Disease.
Fortel, I., et al.
2023,  
Frontiers in aging neuroscience
An interpretable Alzheimer's disease oligogenic risk score informed by neuroimaging biomarkers improves risk prediction and stratification.
Suh, EH., et al.
2023,  
Digital health
Medical artificial intelligence ethics: A systematic review of empirical studies.
Tang, L., et al.
2023,  
Digital health
The spread of COVID-19 vaccine information in Arabic on YouTube: A network exposure study.
Zeid, N., et al.
2023,  
Journal of machine learning research : JMLR
Inference for a Large Directed Acyclic Graph with Unspecified Interventions.
Li, C., et al.
2023,  
Journal of the American Statistical Association
Causal Inference in Transcriptome-Wide Association Studies with Invalid Instruments and GWAS Summary Data.
Xue, H., et al.
2023,  
Frontiers in dementia
Matching science to reality: how to deploy a participant-driven digital brain health platform.
Anda-Duran, ID., et al.
2023,  
Frontiers in dementia
Prediction of Progression from Mild Cognitive Impairment to Alzheimer's disease with Longitudinal and Multimodal Data.
Ding, H., et al.
2023,  
Frontiers in dementia
Association Between Acoustic Features and Brain Volumes: the Framingham Heart Study.
Ding, H., et al.
2023,  
Frontiers in cardiovascular medicine
Association of lifestyle with deep learning predicted electrocardiographic age.
Zhang, C., et al.
2023,  
Journal of Alzheimer's disease : JAD
Cerebral Gray and White Matter Monogalactosyl Diglyceride Levels Rise with the Progression of Alzheimer's Disease.
Blusztajn, JK., et al.
2023,  
Journal of Alzheimer's disease : JAD
Multimodal Machine Learning for 10-Year Dementia Risk Prediction: The Framingham Heart Study.
Ding, H., et al.
2023,  
Frontiers in digital health
Technology engagement is associated with higher perceived physical well-being in stroke patients prescribed smartwatches for atrial fibrillation detection.
Mensah Otabil, E., et al.
2023,  
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
Comparing Amyloid Imaging Normalization Strategies for Alzheimer's Disease Classification using an Automated Machine Learning Pipeline.
Tong, B., et al.
2023,  
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
Discovering Precision AD Biomarkers with Varying Prognosis Effects in Genetics Driven Subpopulations.
Lee, BN., et al.
2023,  
AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science
Exploring Automated Machine Learning for Cognitive Outcome Prediction from Multimodal Brain Imaging using STREAMLINE.
Wang, X., et al.
2023,  
Alzheimer's & dementia (New York, N. Y.)
Listening session with the US Food and Drug Administration, Lewy Body Dementia Association, and an expert panel.
Sabbagh, MN., et al.
2023,  
Alzheimer's & dementia (New York, N. Y.)
Alzheimer's disease drug development pipeline: 2023.
Cummings, J., et al.
2023,  
Alzheimer's & dementia (New York, N. Y.)
PDE5 inhibitor drugs for use in dementia.
Hainsworth, AH., et al.
2023,  
Computational and structural biotechnology journal
Accurate prediction of functional effect of single amino acid variants with deep learning.
Derbel, H., et al.
2022
2022,  
Acta neuropathologica
Neuropathologic scales of cerebrovascular disease associated with diffusion changes on MRI.
Nguyen, AT., et al.
2022,  
Brain : a journal of neurology
Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan.
Luo, J., et al.
2022,  
Translational psychiatry
The impact of increasing levels of blood C-reactive protein on the inflammatory loci SPI1 and CD33 in Alzheimer's disease.
Huang, J., et al.
2022,  
Journal of computational biology : a journal of computational molecular cell biology
Multimodal Genotype and Phenotype Data Integration to Improve Partial Data-Based Longitudinal Prediction.
Ganjdanesh, A., et al.
2022,  
JAMA network open
Development and Validation of a Prediction Model for Need for Massive Transfusion During Surgery Using Intraoperative Hemodynamic Monitoring Data.
Lee, SM., et al.
2022,  
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine
Consistency of Graph Theoretical Measurements of Alzheimer's Disease Fiber Density Connectomes Across Multiple Parcellation Scales.
Xu, F., et al.
2022,  
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine
Using Optimal Transport to Improve Spherical Harmonic Quantification of Complex Biological Shapes.
Wang, Z., et al.
2022,  
Genetic epidemiology
Statistical power of transcriptome-wide association studies.
He, R., et al.
2022,  
Journal of medical Internet research
Association Between Acoustic Features and Neuropsychological Test Performance in the Framingham Heart Study: Observational Study.
Ding, H., et al.
2022,  
NPJ digital medicine
Factors associated with long-term use of digital devices in the electronic Framingham Heart Study.
Pathiravasan, CH., et al.
2022,  
Genetic epidemiology
Genetic heterogeneity: Challenges, impacts, and methods through an associative lens.
Woodward, AA., et al.
2022,  
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine
Mediation Analysis and Mixed-Effects Models for the Identification of Stage-specific Imaging Genetics Patterns in Alzheimer's Disease.
Pala, D., et al.
2022,  
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine
Preference Matrix Guided Sparse Canonical Correlation Analysis for Genetic Study of Quantitative Traits in Alzheimer's Disease.
Sha, J., et al.
2022,  
Journal of clinical medicine
Genome-Wide Pleiotropy Study Identifies Association of PDGFB with Age-Related Macular Degeneration and COVID-19 Infection Outcomes.
Chung, J., et al.
2022,  
Alzheimer's research & therapy
Synergistic interaction of high blood pressure and cerebral beta-amyloid on tau pathology.
Kim, T., et al.
2022,  
Annals of clinical and translational neurology
Vascular endothelial-cadherin as a marker of endothelial injury in preclinical Alzheimer disease.
Tarawneh, R., et al.
2022,  
Genome medicine
Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes.
Yang, C., et al.
2022,  
Nature genetics
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.
Holstege, H., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population.
Godrich, D., et al.
2022,  
Nature
Medin co-aggregates with vascular amyloid-β in Alzheimer's disease.
Wagner, J., et al.
2022,  
Nature neuroscience
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment.
Chiou, KL., et al.
2022,  
European journal of human genetics : EJHG
Exploiting family history in aggregation unit-based genetic association tests.
Wang, Y., et al.
2022,  
Neurology
Association of Red Blood Cell Omega-3 Fatty Acids With MRI Markers and Cognitive Function in Midlife: The Framingham Heart Study.
Satizabal, CL., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Progranulin mutations in clinical and neuropathological Alzheimer's disease.
Vardarajan, BN., et al.
2022,  
Molecular neurodegeneration
ApoE in Alzheimer's disease: pathophysiology and therapeutic strategies.
Raulin, A., et al.
2022,  
Molecular neurodegeneration
Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination.
Wang, N., et al.
2022,  
Nature
Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid.
Drieu, A., et al.
2022,  
Journal of geriatric psychiatry and neurology
Towards Defining the Neuroanatomical Basis of Late-Onset Psychiatric Symptoms.
Barker, MS., et al.
2022,  
Briefings in bioinformatics
Integrating multi-omics summary data using a Mendelian randomization framework.
Jin, C., et al.
2022,  
JAMA
Development of a Prediction Model for Ascending Aortic Diameter Among Asymptomatic Individuals.
Pirruccello, JP., et al.
2022,  
Scientific reports
The association between eicosanoids and incident atrial fibrillation in the Framingham Heart Study.
Kornej, J., et al.
2022,  
Toxins
Omics Methods in Toxins Research-A Toolkit to Drive the Future of Scientific Inquiry.
Romano, JD.
2022,  
Science advances
Generative and reproducible benchmarks for comprehensive evaluation of machine learning classifiers.
Orzechowski, P.
2022,  
NPJ digital medicine
Multimodal machine learning in precision health: A scoping review.
Kline, A., et al.
2022,  
Cell reports
Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease.
Xu, J., et al.
2022,  
iScience
Association of low meal frequency with decreased in vivo Alzheimer's pathology.
Kim, JW., et al.
2022,  
Acta neuropathologica
Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers.
Jansen, IE., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease.
Jun, GR., et al.
2022,  
Medical care
Identifying Medicare Beneficiaries With Delirium.
Moura, LMVR., et al.
2022,  
Journal of psychiatric research
Association of autoimmune diseases with Alzheimer's disease: A mendelian randomization study.
Yeung, CHC., et al.
2022,  
Neuron
Microglial efferocytosis: Diving into the Alzheimer's disease gene pool.
Romero-Molina, C., et al.
2022,  
Cell reports
Spatiotemporal and genetic regulation of A-to-I editing throughout human brain development.
Cuddleston, WH., et al.
2022,  
Molecular psychiatry
Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.
Lahti, J., et al.
2022,  
Neurobiology of disease
Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities.
Katsumata, Y., et al.
2022,  
Proteomics
29-Plex tandem mass tag mass spectrometry enabling accurate quantification by interference correction.
Sun, H., et al.
2022,  
Acta neuropathologica
Rainwater Charitable Foundation criteria for the neuropathologic diagnosis of progressive supranuclear palsy.
Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model.
Rickner, HD., et al.
2022,  
Genome research
Mosaic loss of Chromosome Y in aged human microglia.
Vermeulen, MC., et al.
2022,  
Human genetics
Genome interpretation using in silico predictors of variant impact.
Katsonis, P., et al.
2022,  
Cardiovascular digital health journal
Psychosocial measures in relation to smartwatch alerts for atrial fibrillation detection.
Filippaios, A., et al.
2022,  
Computer science & information technology
Tensor-Based Multi-Modality Feature Selection and Regression for Alzheimer's Disease Diagnosis.
Yu, J., et al.
2022,  
Human molecular genetics
Quantitative trait locus (xQTL) approaches identify risk genes and drug targets from human non-coding genomes.
Bykova, M., et al.
2022,  
Cell reports. Medicine
Transcriptomics-based network medicine approach identifies metformin as a repurposable drug for atrial fibrillation.
Lal, JC., et al.
2022,  
Human molecular genetics
Human Molecular Genetics Review Issue 2022.
Cheng, F.
2022,  
Psychiatry and clinical neurosciences
Spouse bereavement and brain pathologies: A propensity score matching study.
Kim, JW., et al.
2022,  
Communications biology
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Baloni, P., et al.
2022,  
Translational neurodegeneration
Myelin repair in Alzheimer's disease: a review of biological pathways and potential therapeutics.
Hirschfeld, LR., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Identifying differential regulatory control of APOE ɛ4 on African versus European haplotypes as potential therapeutic targets.
Nuytemans, K., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.
Gao, Y., et al.
2022,  
Nature biotechnology
DIALOGUE maps multicellular programs in tissue from single-cell or spatial transcriptomics data.
Jerby-Arnon, L.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk.
Hu, Y., et al.
2022,  
Molecular psychiatry
Cognitive performance protects against Alzheimer's disease independently of educational attainment and intelligence.
Hu, Y., et al.
2022,  
Neurobiology of aging
RNASE6 is a novel modifier of APOE-ε4 effects on cognition.
Seto, M., et al.
2022,  
Movement disorders : official journal of the Movement Disorder Society
Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.
Hopfner, F., et al.
2022,  
HGG advances
A scalable Bayesian functional GWAS method accounting for multivariate quantitative functional annotations with applications for studying Alzheimer disease.
Chen, J., et al.
2022,  
Annals of translational medicine
Causal effects of serum sex hormone binding protein levels on the risk of amyotrophic lateral sclerosis: a mendelian randomization study.
Ou, Y., et al.
2022,  
Human molecular genetics
Scalable approaches for functional analyses of whole-genome sequencing non-coding variants.
Kuksa, PP., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Whole genome sequencing-based copy number variations reveal novel pathways and targets in Alzheimer's disease.
Ming, C., et al.
2022,  
Human molecular genetics
Non-coding RNAs in Alzheimer's disease: perspectives from omics studies.
Wang, E., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
The National Institute on Aging Late-Onset Alzheimer's Disease Family Based Study: A resource for genetic discovery.
Reyes-Dumeyer, D., et al.
2022,  
Annals of clinical and translational neurology
A population-based meta-analysis of circulating GFAP for cognition and dementia risk.
Gonzales, MM., et al.
2022,  
Neurology. Genetics
A Fast and Robust Strategy to Remove Variant-Level Artifacts in Alzheimer Disease Sequencing Project Data.
Belloy, ME., et al.
2022,  
Statistics in medicine
Deep reinforcement learning for personalized treatment recommendation.
Liu, M., et al.
2022,  
Nature communications
Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.
Young, WJ., et al.
2022,  
Human genetics
The promise of automated machine learning for the genetic analysis of complex traits.
Manduchi, E., et al.
2022,  
Patterns (New York, N.Y.)
Knowledge-guided deep learning models of drug toxicity improve interpretation.
Hao, Y., et al.
2022,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Sparse Interpretation of Graph Convolutional Networks for Multi-Modal Diagnosis of Alzheimer's Disease.
Zhou, H., et al.
2022,  
Neurology
Association Between Enlarged Perivascular Spaces and Cognition in a Memory Clinic Population.
Choe, YM., et al.
2022,  
The journals of gerontology. Series A, Biological sciences and medical sciences
Association Between Mediterranean Diet and Functional Status in Older Adults: A Longitudinal Study Based on the Washington Heights-Inwood Columbia Aging Project.
Guo, J., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
The contribution of behavioral features to caregiver burden in FTLD spectrum disorders.
Silverman, HE., et al.
2022,  
Alzheimer's research & therapy
Distinct sex-specific DNA methylation differences in Alzheimer's disease.
C Silva, T., et al.
2022,  
Brain sciences
Determining Whether Sex and Zygosity Modulates the Association between APOE4 and Psychosis in a Neuropathologically-Confirmed Alzheimer's Disease Cohort.
Valcic, M., et al.
2022,  
Bioinformatics (Oxford, England)
Omnibus and robust deconvolution scheme for bulk RNA sequencing data integrating multiple single-cell reference sets and prior biological knowledge.
Chen, C., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer's Symposium.
Quiroz, YT., et al.
2022,  
Genes
Combination of Serum and Plasma Biomarkers Could Improve Prediction Performance for Alzheimer's Disease.
Zhang, F., et al.
2022,  
Molecular neurodegeneration
LRP1 is a neuronal receptor for α-synuclein uptake and spread.
Chen, K., et al.
2022,  
Trends in genetics : TIG
'Fly-ing' from rare to common neurodegenerative disease mechanisms.
Ma, M., et al.
2022,  
STAR protocols
Using population-scale transcriptomic and genomic data to map 3' UTR alternative polyadenylation quantitative trait loci.
Zou, X., et al.
2022,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Explainable Contrastive Multiview Graph Representation of Brain, Mind, and Behavior.
Zhao, C., et al.
2022,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Revealing Continuous Brain Dynamical Organization with Multimodal Graph Transformer.
Zhao, C., et al.
2022,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Predicting Spatio-Temporal Human Brain Response Using fMRI.
Zhao, C., et al.
2022,  
BMC bioinformatics
Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data.
Mai, H., et al.
2022,  
BMC bioinformatics
Deep multiview learning to identify imaging-driven subtypes in mild cognitive impairment.
Feng, Y., et al.
2022,  
... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics
Genomics transformer for diagnosing Parkinson's disease.
Reyes, DM., et al.
2022,  
Cell genomics
Identification of risk genes for Alzheimer's disease by gene embedding.
Lagisetty, Y., et al.
2022,  
Journal of medical Internet research
Racial Bias Beliefs Related to COVID-19 Among Asian Americans, Native Hawaiians, and Pacific Islanders: Findings From the COVID-19 Effects on the Mental and Physical Health of Asian Americans and Pacific Islanders Survey Study (COMPASS).
Park, VT., et al.
2022,  
BMC medical genomics
Identifying genetic markers enriched by brain imaging endophenotypes in Alzheimer's disease.
Kim, M., et al.
2022,  
Genes
Mining High-Level Imaging Genetic Associations via Clustering AD Candidate Variants with Similar Brain Association Patterns.
Wu, R., et al.
2022,  
Nature genetics
Genetics of the human microglia regulome refines Alzheimer's disease risk loci.
Kosoy, R., et al.
2022,  
JAMA network open
Use of a Digital Assistant to Report COVID-19 Rapid Antigen Self-test Results to Health Departments in 6 US Communities.
Multi-Omics-Based Autophagy-Related Untypical Subtypes in Patients with Cerebral Amyloid Pathology.
Park, J., et al.
2022,  
Nature aging
Designing the next-generation clinical care pathway for Alzheimer's disease.
Hampel, H., et al.
2022,  
Neurology
Effects of Sex, APOE4, and Lifestyle Activities on Cognitive Reserve in Older Adults.
Pa, J., et al.
2022,  
Proceedings of the National Academy of Sciences of the United States of America
Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation.
Saroja, SR., et al.
2022,  
Methods (San Diego, Calif.)
Linear linking for related traits (LLRT): A novel method for the harmonization of cognitive domains with no or few common items.
Nichols, EL., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau.
Frank, B., et al.
2022,  
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Genome-wide association study of brain arteriolosclerosis.
Shade, LM., et al.
2022,  
Nature neuroscience
Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function.
Liu, C., et al.
2022,  
Human molecular genetics
Genetic architecture of RNA editing regulation in Alzheimer's disease across diverse ancestral populations.
Gardner, OK., et al.
2022,  
NeuroImage
Covariance shrinkage can assess and improve functional connectomes.
Honnorat, N.
2022,  
Proceedings of the National Academy of Sciences of the United States of America
Stroke-associated intergenic variants modulate a human FOXF2 transcriptional enhancer.
Ryu, J., et al.
2022,  
Nature communications
The causes and consequences of Alzheimer's disease: phenome-wide evidence from Mendelian randomization.
Korologou-Linden, R., et al.
2022,  
Applied sciences (Basel, Switzerland)
Hyperparameter Tuning with High Performance Computing Machine Learning for Imbalanced Alzheimer's Disease Data.
Zhang, F., et al.
2022,  
Acta neuropathologica
Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts.
Nelson, PT., et al.
2022,  
Brain : a journal of neurology
Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke.
Ibanez, L., et al.
2022,  
Nature genetics
DeepLoop robustly maps chromatin interactions from sparse allele-resolved or single-cell Hi-C data at kilobase resolution.
Zhang, S., et al.
2022,  
PLoS genetics
Fine-mapping from summary data with the "Sum of Single Effects" model.
Zou, Y., et al.
2022,  
International journal of environmental research and public health
Examine Race/Ethnicity Disparities in Perception, Intention, and Screening of Dementia in a Community Setting: Scoping Review.
Lee, S., et al.
2022,  
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
FiberNeat: Unsupervised White Matter Tract Filtering.
Chandio, BQ., et al.
2022,  
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Attention-based multiple instance learning with self-supervision to predict microsatellite instability in colorectal cancer from histology whole-slide images.
Leiby, JS., et al.
2022,  
Cells
A Method for Bridging Population-Specific Genotypes to Detect Gene Modules Associated with Alzheimer's Disease.
Dai, Y., et al.
2022,  
Nucleic acids research
EPIMUTESTR: a nearest neighbor machine learning approach to predict cancer driver genes from the evolutionary action of coding variants.
Parvandeh, S., et al.
2022,  
PLoS computational biology
Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer's disease.
Gupta, C., et al.
2022,  
medRxiv : the preprint server for health sciences
Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer and coronary disease pathways.
Wang, L., et al.
2022,  
Acta neuropathologica
FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer's disease.
Lee, AJ., et al.
2022,  
Brain, behavior, & immunity - health
Infection and inflammation: New perspectives on Alzheimer's disease.
Whitson, HE., et al.
2022,  
HGG advances
The genetic architecture of Alzheimer disease risk in the Ohio and Indiana Amish.
Osterman, MD., et al.
2022,  
Human molecular genetics
Accounting for nonlinear effects of gene expression identifies additional associated genes in transcriptome-wide association studies.
Lin, Z., et al.
2022,  
Brain : a journal of neurology
Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.
Eissman, JM., et al.
2022,  
Alzheimer's research & therapy
Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways.
Ibanez, KR., et al.
2022,  
Scientific reports
Using a two-sample mendelian randomization analysis to explore the relationship between physical activity and Alzheimer's disease.
Zhang, B., et al.
2022,  
PLoS genetics
A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer's Disease in African Ancestry.
Rajabli, F., et al.
2022,  
Annals of neurology
Association of Apolipoprotein E ɛ4 Allele with Enlarged Perivascular Spaces.
Pinheiro, A., et al.
2022,  
Annals of neurology
Menopause Status Moderates Sex Differences in Tau Burden: A Framingham PET Study.
Buckley, RF., et al.
2022,  
Neurology
Genetic Risk, Midlife Life's Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study.
Tin, A., et al.
2022,  
Journal of the American College of Cardiology
Polygenic Score Assessed in Young Adulthood and Onset of Subclinical Atherosclerosis and Coronary Heart Disease.
Emdin, CA., et al.
2022,  
Annual review of biochemistry
Lipoproteins in the Central Nervous System: From Biology to Pathobiology.
Raulin, A., et al.
2022,  
Acta neuropathologica
APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer's disease with Lewy body pathology.
Jin, Y., et al.
2022,  
Nature protocols
Chromatin accessibility profiling by ATAC-seq.
Grandi, FC., et al.
2022,  
American journal of human genetics
Integration of rare expression outlier-associated variants improves polygenic risk prediction.
Smail, C., et al.
2022,  
Journal of racial and ethnic health disparities
Differences in COVID-19 Vaccine Concerns Among Asian Americans and Pacific Islanders: The COMPASS Survey.
Ta Park, V., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Rates of longitudinal change in 18 F-flortaucipir PET vary by brain region, cognitive impairment, and age in atypical Alzheimer's disease
2022,  
BMC genomics
Integrative analysis of summary data from GWAS and eQTL studies implicates genes differentially expressed in Alzheimer's disease.
Lee, B., et al.
2022,  
Network neuroscience (Cambridge, Mass.)
Inferring excitation-inhibition dynamics using a maximum entropy model unifying brain structure and function.
Fortel, I., et al.
2022,  
Nature communications
Evolutionary action of mutations reveals antimicrobial resistance genes in Escherichia coli.
Marciano, DC., et al.
2022,  
IEEE transactions on neural networks and learning systems
Significance Tests of Feature Relevance for a Black-Box Learner.
Dai, B., et al.
2022,  
Current opinion in structural biology
Editorial overview: Artificial intelligence (AI) methodologies in structural biology.
Cheng, F.
2022,  
Research square
A comprehensive SARS-CoV-2-human protein-protein interactome network identifies pathobiology and host-targeting therapies for COVID-19.
Zhou, Y., et al.
2022,  
Molecular psychiatry
Admixture Mapping of Alzheimer's disease in Caribbean Hispanics identifies a new locus on 22q13.1.
Kizil, C., et al.
2022,  
Cell
Cholesterol and matrisome pathways dysregulated in astrocytes and microglia.
Tcw, J., et al.
2022,  
Genome medicine
Penetrance estimation of Alzheimer disease in SORL1 loss-of-function variant carriers using a family-based strategy and stratification by APOE genotypes.
Schramm, C., et al.
2022,  
Aging cell
Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells.
You, Y., et al.
2022,  
PLoS genetics
Integrated analysis of direct and proxy genome wide association studies highlights polygenicity of Alzheimer's disease outside of the APOE region.
de la Fuente, J., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease.
Horgusluoglu, E., et al.
2022,  
Nature reviews. Endocrinology
The emerging role of lipidomics in prediction of diseases.
Han, X.
2022,  
American journal of human genetics
Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss.
Trpchevska, N., et al.
2022,  
Nutrients
Red Blood Cell DHA Is Inversely Associated with Risk of Incident Alzheimer's Disease and All-Cause Dementia: Framingham Offspring Study.
Sala-Vila, A., et al.
2022,  
Biological psychiatry. Cognitive neuroscience and neuroimaging
Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes.
Le Grand, Q., et al.
2022,  
Brain : a journal of neurology
Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.
Mishra, A., et al.
2022,  
Neurology
Clinicopathologic Factors Associated With Reversion to Normal Cognition in Patients With Mild Cognitive Impairment.
Li, Z., et al.
2022,  
Journal of neuroinflammation
High-fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner.
Gannon, OJ., et al.
2022,  
Nutrition, metabolism, and cardiovascular diseases : NMCD
A deep learning model for screening type 2 diabetes from retinal photographs.
Yun, J., et al.
2022,  
BMC medical genomics
Identifying Alzheimer's genes via brain transcriptome mapping.
Baik, JY., et al.
2022,  
Genome research
A general calculus of fitness landscapes finds genes under selection in cancers.
Hsu, T., et al.
2022,  
PLoS genetics
A practical problem with Egger regression in Mendelian randomization.
Lin, Z., et al.
2022,  
Protein science : a publication of the Protein Society
Shape shifting: The multiple conformational substates of the PTEN N-terminal PIP2 -binding domain.
Dawson, JE., et al.
2022,  
Journal of immunology (Baltimore, Md. : 1950)
Peripheral sTREM2-Related Inflammatory Activity Alterations in Early-Stage Alzheimer's Disease.
Weber, GE., et al.
2022,  
Journal of clinical periodontology
Replication of gene polymorphisms associated with periodontitis-related traits in an elderly cohort: the Washington Heights/Inwood Community Aging Project Ancillary Study of Oral Health.
Yang, T., et al.
2022,  
Current protocols
Molecular Quantitative Trait Locus Mapping in Human Complex Diseases.
Olayinka, OA., et al.
2022,  
Neurobiology of disease
Multi-transcriptomic analysis points to early organelle dysfunction in human astrocytes in Alzheimer's disease.
Galea, E., et al.
2022,  
Aging cell
Transcriptional landscape of human microglia implicates age, sex, and APOE-related immunometabolic pathway perturbations.
Patel, T., et al.
2022,  
The European journal of neuroscience
Lifelong chronic psychosocial stress induces a proteomic signature of Alzheimer's disease in wildtype mice.
Lyons, CE., et al.
2022,  
JAMA psychiatry
Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression.
Wen, J., et al.
2022,  
Hypertension (Dallas, Tex. : 1979)
Arterial Stiffness and Long-Term Risk of Health Outcomes: The Framingham Heart Study.
Vasan, RS., et al.
2022,  
Nature neuroscience
Genetic variants associated with longitudinal changes in brain structure across the lifespan.
Brouwer, RM., et al.
2022,  
Journal of medical Internet research
Associations Between the Digital Clock Drawing Test and Brain Volume: Large Community-Based Prospective Cohort (Framingham Heart Study).
Yuan, J., et al.
2022,  
Med (New York, N.Y.)
Integrating functional genomics with genetics to understand the biology of ALS and FTD.
Cruchaga, C.
2022,  
Neuron
ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias.
Martens, YA., et al.
2022,  
Biological psychiatry global open science
Disentangling Independent and Mediated Causal Relationships Between Blood Metabolites, Cognitive Factors, and Alzheimer's Disease.
Lord, J., et al.
2022,  
Nature neuroscience
Integrating whole-genome sequencing with multi-omic data reveals the impact of structural variants on gene regulation in the human brain.
Vialle, RA., et al.
2022,  
Scientific reports
Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.
Heath, L., et al.
2022,  
BMC medical genomics
Integrative analysis of eQTL and GWAS summary statistics reveals transcriptomic alteration in Alzheimer brains.
Varathan, P., et al.
2022,  
Scientific reports
ODACH: a one-shot distributed algorithm for Cox model with heterogeneous multi-center data.
Luo, C., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Dementia in Africa: Current evidence, knowledge gaps, and future directions.
Akinyemi, RO., et al.
2022,  
NeuroImage
Hemodynamic and metabolic correspondence of resting-state voxel-based physiological metrics in healthy adults.
Deng, S., et al.
2022,  
American journal of human genetics
Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits.
Highland, HM., et al.
2022,  
American journal of human genetics
Family history aggregation unit-based tests to detect rare genetic variant associations with application to the Framingham Heart Study.
Wang, Y., et al.
2022,  
Communications biology
Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels.
Sarnowski, C., et al.
2022,  
Nature genetics
New insights into the genetic etiology of Alzheimer's disease and related dementias.
Bellenguez, C., et al.
2022,  
Cells
Identifying Blood Biomarkers for Dementia Using Machine Learning Methods in the Framingham Heart Study.
Lin, H., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Replication study of AD-associated rare variants.
Neupane, A., et al.
2022,  
Genome research
An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns.
Jin, B., et al.
2022,  
Analytical chemistry
Deep Single-Cell-Type Proteome Profiling of Mouse Brain by Nonsurgical AAV-Mediated Proximity Labeling.
Sun, X., et al.
2022,  
Neuron
Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility.
Meijer, M., et al.
2022,  
Neurobiology of disease
Soluble TREM2: Innocent bystander or active player in neurological diseases?
Filipello, F., et al.
2022,  
The Lancet. Neurology
Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study.
Morenas-Rodríguez, E., et al.
2022,  
Sleep
Future directions to address sleep health disparity among Asian American immigrants.
Song, Y., et al.
2022,  
JAMA psychiatry
Associations Between Neuropsychiatric Symptoms and Neuropathological Diagnoses of Alzheimer Disease and Related Dementias.
Devanand, DP., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease.
Veitch, DP., et al.
2022,  
Molecular neurodegeneration
Solving neurodegeneration: common mechanisms and strategies for new treatments.
Wareham, LK., et al.
2022,  
Journal of magnetic resonance imaging : JMRI
Deep Generative Medical Image Harmonization for Improving Cross-Site Generalization in Deep Learning Predictors.
Bashyam, VM., et al.
2022,  
Human brain mapping
Mitigating site effects in covariance for machine learning in neuroimaging data.
Chen, AA., et al.
2022,  
Briefings in bioinformatics
Deep learning-based identification of genetic variants: application to Alzheimer's disease classification.
Jo, T., et al.
2022,  
Proceedings. IEEE International Symposium on Biomedical Imaging
INVESTIGATING THE EFFECT OF TAU DEPOSITION AND APOE ON HIPPOCAMPAL MORPHOMETRY IN ALZHEIMER'S DISEASE: A FEDERATED CHOW TEST MODEL.
Wu, J., et al.
2022,  
Proceedings. IEEE International Symposium on Biomedical Imaging
HIERARCHICAL BRAIN EMBEDDING USING EXPLAINABLE GRAPH LEARNING.
Tang, H., et al.
2022,  
Acta neuropathologica
Transcriptomic analysis of frontotemporal lobar degeneration with TDP-43 pathology reveals cellular alterations across multiple brain regions.
Hasan, R., et al.
2022,  
Nature
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A.
Brown, A., et al.
2022,  
Scientific reports
The association between social network index, atrial fibrillation, and mortality in the Framingham Heart Study.
Kornej, J., et al.
2022,  
Acta neuropathologica communications
Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease.
Chen, H., et al.
2022,  
Neurobiology of disease
APOE4 confers transcriptomic and functional alterations to primary mouse microglia.
Machlovi, SI., et al.
2022,  
Neurobiology of aging
Association between WWOX/MAF variants and dementia-related neuropathologic endophenotypes.
Dugan, AJ., et al.
2022,  
Epilepsia
Association of ultra-rare coding variants with genetic generalized epilepsy: A case-control whole exome sequencing study.
Koko, M., et al.
2022,  
Nature neuroscience
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain.
Marsh, SE., et al.
2022,  
NAR genomics and bioinformatics
FILER: a framework for harmonizing and querying large-scale functional genomics knowledge.
Kuksa, PP., et al.
2022,  
Molecular neurodegeneration
Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer's disease: review, recommendation, implementation and application.
Wang, M., et al.
2022,  
Stroke
Clonal Hematopoiesis Is Associated With Higher Risk of Stroke.
Bhattacharya, R., et al.
2022,  
Neurology
Association of Serum Neurofilament Light Chain Concentration and MRI Findings in Older Adults: The Cardiovascular Health Study.
Fohner, AE., et al.
2022,  
Translational psychiatry
Correction: Association of low-frequency and rare coding variants with information processing speed.
Bressler, J., et al.
2022,  
Neurology
Association of Loneliness With 10-Year Dementia Risk and Early Markers of Vulnerability for Neurocognitive Decline.
Salinas, J., et al.
2022,  
Journal of lipid research
The foundations and development of lipidomics.
Han, X.
2022,  
Current opinion in neurobiology
Recent insights into the role of glia and oxidative stress in Alzheimer's disease gained from Drosophila.
Goodman, LD.
2022,  
International journal of environmental research and public health
Ethnicity, Social, and Clinical Risk Factors to Tooth Loss among Older Adults in the U.S., NHANES 2011-2018.
Lee, H., et al.
2022,  
Medical image analysis
Multi-task learning based structured sparse canonical correlation analysis for brain imaging genetics.
Kim, M., et al.
2022,  
Medical image analysis
Embracing the disharmony in medical imaging: A Simple and effective framework for domain adaptation.
Wang, R., et al.
2022,  
Current opinion in structural biology
Interpretable artificial intelligence and exascale molecular dynamics simulations to reveal kinetics: Applications to Alzheimer's disease.
Martin, W., et al.
2022,  
Aging cell
Aging-related cell type-specific pathophysiologic immune responses that exacerbate disease severity in aged COVID-19 patients.
Hou, Y., et al.
2022,  
Neurobiology of aging
Cognitive reserve proxies, Alzheimer pathologies, and cognition.
Ko, K., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Social network characteristics moderate associations between cortical thickness and cognitive functioning in older adults.
Sharifian, N., et al.
2022,  
BMJ open
Adherence to COVID-19 protective behaviours in India from May to December 2020: evidence from a nationally representative longitudinal survey.
Schaner, S., et al.
2022,  
Nature communications
Inferring protein expression changes from mRNA in Alzheimer's dementia using deep neural networks.
Tasaki, S., et al.
2022,  
Alzheimer's research & therapy
Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease.
Panitch, R., et al.
2022,  
BMJ open
Association of social isolation, loneliness and genetic risk with incidence of dementia: UK Biobank Cohort Study.
Elovainio, M., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Analysis of high-risk pedigrees identifies 11 candidate variants for Alzheimer's disease.
Teerlink, CC., et al.
2022,  
Circulation
Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease.
Katz, DH., et al.
2022,  
Stroke
Imaging Markers of Vascular Brain Health: Quantification, Clinical Implications, and Future Directions.
Vemuri, P., et al.
2022,  
Neurology. Genetics
Migraine, Stroke, and Cervical Arterial Dissection: Shared Genetics for a Triad of Brain Disorders With Vascular Involvement.
Daghlas, I., et al.
2022,  
Aging
Mid-life epigenetic age, neuroimaging brain age, and cognitive function: coronary artery risk development in young adults (CARDIA) study.
Zheng, Y., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease.
Zhang, X., et al.
2022,  
Alzheimer's research & therapy
Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping.
Belloy, ME., et al.
2022,  
Alzheimer's & dementia (New York, N. Y.)
Chronic neuropsychiatric sequelae of SARS-CoV-2: Protocol and methods from the Alzheimer's Association Global Consortium.
de Erausquin, GA., et al.
2022,  
Journal of Alzheimer's disease : JAD
Functional Neural Correlates of Semantic Fluency Task Performance in Mild Cognitive Impairment and Alzheimer's Disease: An FDG-PET Study.
Ahn, H., et al.
2022,  
Journal of Alzheimer's disease : JAD
Late-Life Physical Activities Moderate the Relationship of Amyloid-β Pathology with Neurodegeneration in Individuals Without Dementia.
Sohn, BK., et al.
2022,  
Journal of Alzheimer's disease : JAD
Measuring Subjective Cognitive Decline in Older Adults: Harmonization Between the Cognitive Change Index and the Measurement of Everyday Cognition Instruments.
Wells, LF., et al.
2022,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Immunity gene IFITM3 variant: Relation to cognition and Alzheimer's disease pathology.
Pyun, J., et al.
2022,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Integrative analysis of DNA methylation and gene expression identifies genes associated with biological aging in Alzheimer's disease.
Kim, B., et al.
2022,  
PloS one
Gut microbiome alterations in preclinical Alzheimer's disease.
Jung, JH., et al.
2022,  
PloS one
Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk.
Ali, M., et al.
2022,  
Journal of Alzheimer's disease : JAD
Comparative Analysis of Alzheimer's Disease Cerebrospinal Fluid Biomarkers Measurement by Multiplex SOMAscan Platform and Immunoassay-Based Approach.
Timsina, J., et al.
2022,  
PloS one
Cross-national harmonization of cognitive measures across HRS HCAP (USA) and LASI-DAD (India).
Vonk, JMJ., et al.
2022,  
Journal of Alzheimer's disease : JAD
The Advisory Group on Risk Evidence Education for Dementia: Multidisciplinary and Open to All.
Rosen, AC., et al.
2022,  
Frontiers in aging neuroscience
The role of structural variations in Alzheimer's disease and other neurodegenerative diseases.
Wang, H., et al.
2022,  
IEEE/ACM transactions on computational biology and bioinformatics
GuiltyTargets: Prioritization of Novel Therapeutic Targets With Network Representation Learning.
Muslu, O., et al.
2022,  
Journal of Alzheimer's disease : JAD
Predictors of Mortality in Individuals with Dementia in the National Alzheimer's Coordinating Center.
Armstrong, MJ., et al.
2022,  
Journal of Alzheimer's disease : JAD
Investigating Causal Relations Between Circulating Metabolites and Alzheimer's Disease: A Mendelian Randomization Study.
Huang, S., et al.
2022,  
Dementia and geriatric cognitive disorders extra
Early-Stage MRI Volumetric Differences in White Matter Hyperintensity and Temporal Lobe Volumes between Autopsy-Confirmed Alzheimer's Disease, Cerebral Small Vessel Disease, and Mixed Pathologies.
Yang, D.
2022,  
Journal of Alzheimer's disease : JAD
Parkinson's Disease rs117896735 Variant Regulates INPP5F Expression in Brain Tissues and Increases Risk of Alzheimer's Disease.
Xue, F., et al.
2022,  
Journal of Alzheimer's disease : JAD
The Association of Serum Uric Acid Level, Gout, and Alzheimer's Disease: A Bidirectional Mendelian Randomization Study.
Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease.
Kuksa, PP., et al.
2022,  
Journal of Alzheimer's disease : JAD
Polygenic Risk Scores in Alzheimer's Disease Genetics: Methodology, Applications, Inclusion, and Diversity.
Clark, K., et al.
2022,  
Journal of Alzheimer's disease : JAD
Associations Between Brainstem Volume and Alzheimer's Disease Pathology in Middle-Aged Individuals of the Framingham Heart Study.
Jacobs, HIL., et al.
2022,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Blood biomarkers for cognitive decline and clinical progression in a Mexican American cohort.
Gonzales, MM., et al.
2022,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Instrumental validation of free water, peak-width of skeletonized mean diffusivity, and white matter hyperintensities: MarkVCID neuroimaging kits.
Maillard, P., et al.
2022,  
Journal of Alzheimer's disease : JAD
Spillover: The Approval of New Medications for Alzheimer's Disease Dementia Will Impact Biomarker Disclosure Among Asymptomatic Research Participants.
Mozersky, J., et al.
2022,  
Alzheimer's & dementia (Amsterdam, Netherlands)
MRI free water as a biomarker for cognitive performance: Validation in the MarkVCID consortium.
Maillard, P., et al.
2022,  
Journal of Alzheimer's disease : JAD
Plasma EFEMP1 Is Associated with Brain Aging and Dementia: The Framingham Heart Study.
McGrath, ER., et al.
2022,  
Journal of Alzheimer's disease : JAD
Non-Alcoholic Fatty Liver Disease, Liver Fibrosis, and Regional Amyloid-β and Tau Pathology in Middle-Aged Adults: The Framingham Study.
Weinstein, G., et al.
2022,  
Journal of Alzheimer's disease : JAD
Blood Phosphorylated Tau 181 as a Biomarker for Amyloid Burden on Brain PET in Cognitively Healthy Adults.
McGrath, ER., et al.
2022,  
Journal of Alzheimer's disease : JAD
Insulin-Like Growth Factor, Inflammation, and MRI Markers of Alzheimer's Disease in Predominantly Middle-Aged Adults.
Wittfeld, K., et al.
2022,  
Journal of Alzheimer's disease : JAD
Association of Carotid Intima Media Thickening with Future Brain Region Specific Amyloid-β Burden.
Baradaran, H., et al.
2022,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
A blood screening tool for detecting mild cognitive impairment and Alzheimer's disease among community-dwelling Mexican Americans and non-Hispanic Whites: A method for increasing representation of diverse populations in clinical research.
O'Bryant, SE., et al.
2022,  
Developmental neurobiology
Microglial TREM2 in amyotrophic lateral sclerosis.
Xie, M., et al.
2022,  
Nature neuroscience
TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.
Xie, M., et al.
2022,  
Seminars in immunology
APOE mediated neuroinflammation and neurodegeneration in Alzheimer's disease.
Parhizkar, S.
2022,  
International journal of environmental research and public health
Discrimination Experiences during COVID-19 among a National, Multi-Lingual, Community-Based Sample of Asian Americans and Pacific Islanders: COMPASS Findings.
Ta Park, VM., et al.
2022,  
Journal of geriatric psychiatry and neurology
Depression Is Associated With Preserved Cortical Thickness Relative to Apathy in Frontotemporal Dementia.
Basavaraju, R., et al.
2022,  
Human brain mapping
Greater male than female variability in regional brain structure across the lifespan.
Wierenga, LM., et al.
2022,  
Human brain mapping
Testing a convolutional neural network-based hippocampal segmentation method in a stroke population.
Zavaliangos-Petropulu, A., et al.
2022,  
Human brain mapping
Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years.
Dima, D., et al.
2022,  
Human brain mapping
Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years.
Frangou, S., et al.
2022,  
Neurobiology of aging
Tau pathology mediates age effects on medial temporal lobe structure.
Wisse, LE., et al.
2022,  
Medical image analysis
Multi-scale semi-supervised clustering of brain images: Deriving disease subtypes.
Wen, J., et al.
2022,  
Medical image analysis
Multi-Class ASD Classification via Label Distribution Learning with Class-Shared and Class-Specific Decomposition.
Wang, J., et al.
2022,  
BMC genomics
Genome-Wide association study of quantitative biomarkers identifies a novel locus for alzheimer's disease at 12p12.1.
Lee, B., et al.
2022,  
Bioinformatics (Oxford, England)
echolocatoR: an automated end-to-end statistical and functional genomic fine-mapping pipeline.
Schilder, BM., et al.
2022,  
Nature genetics
Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies.
Lopes, KdP., et al.
2022,  
Alzheimer's research & therapy
Correction to: BMI1 is associated with CSF amyloid-β and rates of cognitive decline in Alzheimer's disease.
Kim, JP., et al.
2022,  
Molecular neurodegeneration
Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains.
Bigley, TM., et al.
2022,  
Neurology
Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population.
Angevaare, MJ., et al.
2022,  
Acta neuropathologica
Genome-wide association study and functional validation implicates JADE1 in tauopathy.
Farrell, K., et al.
2022,  
Nature communications
Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants.
Sanders, B., et al.
2022,  
Alzheimer's research & therapy
Mendelian randomization highlights significant difference and genetic heterogeneity in clinically diagnosed Alzheimer's disease GWAS and self-report proxy phenotype GWAX.
Liu, H., et al.
2022,  
Biological psychiatry
Sex Differences in Alzheimer's Disease: Insights From the Multiomics Landscape.
Guo, L., et al.
2022,  
Molecular neurodegeneration
The landscape of human tissue and cell type specific expression and co-regulation of senescence genes.
Xu, P., et al.
2022,  
Journal of Alzheimer's disease : JAD
Proteomic Profiles of Neurodegeneration Among Mexican Americans and Non-Hispanic Whites in the HABS-HD Study.
O'Bryant, SE., et al.
2022,  
Dementia and geriatric cognitive disorders
The Link between APOE4 Presence and Neuropsychological Test Performance among Mexican Americans and Non-Hispanic Whites of the Multiethnic Health & Aging Brain Study - Health Disparities Cohort.
O'Bryant, SE., et al.
2022,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Vascular risk profile and white matter hyperintensity volume among Mexican Americans and non-Hispanic Whites: The HABLE study.
King, KS., et al.
2022,  
Journal of Alzheimer's disease : JAD
Metabolic Factors Are Related to Brain Amyloid Among Mexican Americans: A HABS-HD Study.
O'Bryant, SE., et al.
2022,  
Journal of Alzheimer's disease : JAD
Characterization of Mild Cognitive Impairment and Dementia among Community-Dwelling Mexican Americans and Non-Hispanic Whites.
O'Bryant, SE., et al.
2022,  
Journal of Alzheimer's disease : JAD
Cancer and Vascular Comorbidity Effects on Dementia Risk and Neuropathology in the Oldest-Old.
Lachner, C., et al.
2022,  
Alzheimer's & dementia (New York, N. Y.)
Disentangling tau and brain atrophy cluster heterogeneity across the Alzheimer's disease continuum.
Toledo, JB., et al.
2022,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Uncertainties in the PET defined A-/TNeocortical+ subtype.
Mormino, EC.
2022,  
PloS one
SPARE-Tau: A flortaucipir machine-learning derived early predictor of cognitive decline.
Toledo, JB., et al.
2022,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Identifying imaging genetic associations via regional morphometricity estimation.
Bao, J., et al.
2022,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Identifying highly heritable brain amyloid phenotypes through mining Alzheimer's imaging and sequencing biobank data.
Bao, J., et al.
2022,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Effects of ApoE4 and ApoE2 genotypes on subcortical magnetic susceptibility and microstructure in 27,535 participants from the UK Biobank.
Nir, TM., et al.
2022,  
Frontiers in radiology
Sex Differences in the Metabolome of Alzheimer's Disease Progression.
Zarzar, TG., et al.
2022,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Association of the top 20 Alzheimer's disease risk genes with [
Stage, E., et al.
2022,  
Brain communications
Disentangling Alzheimer's disease neurodegeneration from typical brain ageing using machine learning.
Hwang, G., et al.
2022,  
Proceedings of SPIE--the International Society for Optical Engineering
Harmonization of multi-site functional connectivity measures in tangent space improves brain age prediction.
Zhou, Z., et al.
2022,  
Harvard data science review
Data Flush.
Shen, X., et al.
2022,  
Alzheimer's & dementia (New York, N. Y.)
The Alzheimer's Cell Atlas (TACA): A single-cell molecular map for translational therapeutics accelerator in Alzheimer's disease.
Zhou, Y., et al.
2021
2021,  
European journal of neurology
Clinical, pathological and genetic characteristics of Perry disease-new cases and literature review.
Dulski, J., et al.
2021,  
Molecular neurodegeneration
TDP-43 Pathology in Alzheimer's Disease.
Meneses, A., et al.
2021,  
Proceedings of the National Academy of Sciences of the United States of America
Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer's disease-associated genes.
Moulton, MJ., et al.
2021,  
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine
Interpretable temporal graph neural network for prognostic prediction of Alzheimer's disease using longitudinal neuroimaging data.
Kim, M., et al.
2021,  
Nature aging
Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease.
Fang, J., et al.
2021,  
Autophagy
Loss-of-function mutation in VCP mimics the characteristic pathology as in FTLD-TARDBP.
Wani, A.
2021,  
American journal of human genetics
Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics.
He, Z., et al.
2021,  
Translational psychiatry
Genetically regulated expression in late-onset Alzheimer's disease implicates risk genes within known and novel loci.
Chen, H., et al.
2021,  
Diagnostics (Basel, Switzerland)
Integrated Genomic, Transcriptomic and Proteomic Analysis for Identifying Markers of Alzheimer's Disease.
Madrid, L., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Association of Life's Simple 7 with incident dementia and its modification by the apolipoprotein E genotype.
Guo, J., et al.
2021,  
NeuroImage
Multi-vendor and multisite evaluation of cerebrovascular reactivity mapping using hypercapnia challenge.
Liu, P., et al.
2021,  
Nature communications
A deep learning framework identifies dimensional representations of Alzheimer's Disease from brain structure.
Yang, Z., et al.
2021,  
Nature aging
Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology.
Dehkordi, SK., et al.
2021,  
Acta neuropathologica
Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids.
Zhao, J., et al.
2021,  
IEEE transactions on bio-medical engineering
Improved Prediction of Cognitive Outcomes via Globally Aligned Imaging Biomarker Enrichments Over Progressions.
Lu, L., et al.
2021,  
Proceedings of SPIE--the International Society for Optical Engineering
Alzheimer's Disease Classification Accuracy is Improved by MRI Harmonization based on Attention-Guided Generative Adversarial Networks.
Sinha, S., et al.
2021,  
Alzheimer's research & therapy
Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer's disease.
Park, YH., et al.
2021,  
Alzheimer's research & therapy
Serum zinc levels and in vivo beta-amyloid deposition in the human brain.
Kim, JW., et al.
2021,  
The Journal of clinical investigation
Recipient APOL1 risk alleles associate with death-censored renal allograft survival and rejection episodes.
Zhang, Z., et al.
2021,  
Briefings in bioinformatics
Integrative-omics for discovery of network-level disease biomarkers: a case study in Alzheimer's disease.
Xie, L., et al.
2021,  
Neuron
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors.
Lagomarsino, VN., et al.
2021,  
Translational psychiatry
A missense variant in SHARPIN mediates Alzheimer's disease-specific brain damages.
Park, JY., et al.
2021,  
Journal of neuroimaging : official journal of the American Society of Neuroimaging
Prevalence of incidental brain MRI findings of clinical relevance in a diverse Hispanic/Latino population.
Ivanovic, V., et al.
2021,  
Nature communications
Author Correction: Regulation of local GTP availability controls RAC1 activity and cell invasion.
Bianchi-Smiraglia, A., et al.
2021,  
Analytical chemistry
JUMPt: Comprehensive Protein Turnover Modeling of In Vivo Pulse SILAC Data by Ordinary Differential Equations.
Chepyala, SR., et al.
2021,  
Molecular cell
Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
2021,  
Health promotion international
Use of Korean dramas to facilitate precision mental health understanding and discussion for Asian Americans.
Ta Park, VM., et al.
2021,  
Acta neuropathologica
HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing.
Bampton, A., et al.
2021,  
Cells
KYNA/Ahr Signaling Suppresses Neural Stem Cell Plasticity and Neurogenesis in Adult Zebrafish Model of Alzheimer's Disease.
Siddiqui, T., et al.
2021,  
Alzheimer's research & therapy
BMI1 is associated with CS8F amyloid-β and rates of cognitive decline in Alzheimer's disease.
Kim, JP., et al.
2021,  
Genome research
Bayesian estimation of cell type-specific gene expression with prior derived from single-cell data.
Wang, J., et al.
2021,  
Bioinformatics (Oxford, England)
Identification of cell-type-specific marker genes from co-expression patterns in tissue samples.
Qiu, Y., et al.
2021,  
Molecular psychiatry
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease.
DeMichele-Sweet, MAA., et al.
2021,  
Molecular psychiatry
The acute phase protein lactoferrin is a key feature of Alzheimer's disease and predictor of Aβ burden through induction of APP amyloidogenic processing.
Tsatsanis, A., et al.
2021,  
Molecular psychiatry
Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease.
Panitch, R., et al.
2021,  
Genes & nutrition
Mendelian randomization to evaluate the effect of plasma vitamin C levels on the risk of Alzheimer's disease.
Liu, H., et al.
2021,  
Nature aging
Effect of APOE alleles on the glial transcriptome in normal aging and Alzheimer's disease.
Serrano-Pozo, A., et al.
2021,  
Nature communications
Regulation of local GTP availability controls RAC1 activity and cell invasion.
Bianchi-Smiraglia, A., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants.
Damotte, V., et al.
2021,  
STAR protocols
Preparation of single cell suspensions enriched in mouse brain vascular cells for single-cell RNA sequencing.
Yamazaki, A., et al.
2021,  
Nature reviews. Neurology
The human connectome in Alzheimer disease - relationship to biomarkers and genetics.
Yu, M., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Alzheimer's disease alters oligodendrocytic glycolytic and ketolytic gene expression.
Saito, ER., et al.
2021,  
Nature neuroscience
Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders.
Yang, C., et al.
2021,  
bioRxiv : the preprint server for biology
Weakly activated core inflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer's disease.
Li, F., et al.
2021,  
Nature communications
Large scale enzyme based xenobiotic identification for exposomics.
Liu, KH., et al.
2021,  
Bioinformatics (Oxford, England)
Modeling multifunctionality of genes with secondary gene co-expression networks in human brain provides novel disease insights.
Sánchez, JA., et al.
2021,  
American journal of epidemiology
A Robust Test for Additive Gene-Environment Interaction Under the Trend Effect of Genotype Using an Empirical Bayes-Type Shrinkage Estimator.
Sanyal, N., et al.
2021,  
Annals of neurology
Polygenic Risk Score for Alzheimer's Disease in Caribbean Hispanics.
Sariya, S., et al.
2021,  
Cell systems
Dysregulation of the secretory pathway connects Alzheimer's disease genetics to aggregate formation.
Kuo, C., et al.
2021,  
Alzheimer's research & therapy
Leukotriene receptor antagonist use and cognitive decline in normal cognition, mild cognitive impairment, and Alzheimer's dementia.
Xiong, LY., et al.
2021,  
Acta neuropathologica communications
Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study.
Dugan, AJ., et al.
2021,  
Translational psychiatry
Cortical structure and the risk for Alzheimer's disease: a bidirectional Mendelian randomization study.
Wu, B., et al.
2021,  
medRxiv : the preprint server for health sciences
Olfactory Bulb and Amygdala Gene Expression Changes in Subjects Dying with COVID-19.
Piras, IS., et al.
2021,  
Science translational medicine
In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer's disease pathology and cognitive decline.
Jacobs, HIL., et al.
2021,  
Alzheimer's research & therapy
Herpesvirus infections and Alzheimer's disease: a Mendelian randomization study.
Huang, S., et al.
2021,  
Biomedicines
Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer's and Parkinson's Diseases.
Lam, S., et al.
2021,  
Molecular psychiatry
MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis.
Cao, J., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Midlife vascular risk factors and risk of incident dementia: Longitudinal cohort and Mendelian randomization analyses in the UK Biobank.
Malik, R., et al.
2021,  
Nature genetics
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease.
Wightman, DP., et al.
2021,  
Science translational medicine
APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia.
Liu, C., et al.
2021,  
PLoS genetics
Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences.
Zhan, L., et al.
2021,  
BMC bioinformatics
A pipeline for RNA-seq based eQTL analysis with automated quality control procedures.
Wang, T., et al.
2021,  
Circulation. Cardiovascular imaging
Progress and Research Priorities in Imaging Genomics for Heart and Lung Disease: Summary of an NHLBI Workshop.
Nayor, M., et al.
2021,  
Translational neurodegeneration
Predictability of polygenic risk score for progression to dementia and its interaction with APOE ε4 in mild cognitive impairment.
Pyun, J., et al.
2021,  
Genes
Advances in Genetic and Molecular Understanding of Alzheimer's Disease.
Ibanez, L., et al.
2021,  
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists
Associations Between Loneliness, Reading Ability and Episodic Memory in Non-Hispanic Black and White Older Adults.
Sol, K., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Plasma p-tau181, p-tau217, and other blood-based Alzheimer's disease biomarkers in a multi-ethnic, community study.
Brickman, AM., et al.
2021,  
Environmental health perspectives
Utilizing a Biology-Driven Approach to Map the Exposome in Health and Disease: An Essential Investment to Drive the Next Generation of Environmental Discovery.
Chung, MK., et al.
2021,  
Neurobiology of aging
Linkage of Alzheimer disease families with Puerto Rican ancestry identifies a chromosome 9 locus.
Rajabli, F., et al.
2021,  
Nature genetics
Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer's disease.
Morabito, S., et al.
2021,  
Nature chemistry
SARS-CoV-2 simulations go exascale to predict dramatic spike opening and cryptic pockets across the proteome.
Zimmerman, MI., et al.
2021,  
Medical image analysis
A structural enriched functional network: An application to predict brain cognitive performance.
Kim, M., et al.
2021,  
Nature methods
QSIPrep: an integrative platform for preprocessing and reconstructing diffusion MRI data.
Cieslak, M., et al.
2021,  
Cell reports
Neuronal VCP loss of function recapitulates FTLD-TDP pathology.
Wani, A., et al.
2021,  
Molecular psychiatry
Older molecular brain age in severe mental illness.
Lin, C., et al.
2021,  
BMC medicine
Investigating causal relationships between exposome and human longevity: a Mendelian randomization analysis.
Huang, S., et al.
2021,  
Nature communications
Identifying individuals with high risk of Alzheimer's disease using polygenic risk scores.
Leonenko, G., et al.
2021,  
Cell reports methods
Model-based assessment of mammalian cell metabolic functionalities using omics data.
Richelle, A., et al.
2021,  
Translational psychiatry
Heterogeneous effects of genetic risk for Alzheimer's disease on the phenome.
Wu, HM., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.
Griswold, AJ., et al.
2021,  
STAR protocols
Generation and validation of APOE knockout human iPSC-derived cerebral organoids.
Martens, YA., et al.
2021,  
Cardiovascular research
New biomarkers from multiomics approaches: improving risk prediction of atrial fibrillation.
Kornej, J., et al.
2021,  
Journal of medical Internet research
Association Between the Digital Clock Drawing Test and Neuropsychological Test Performance: Large Community-Based Prospective Cohort (Framingham Heart Study).
Yuan, J., et al.
2021,  
Journal of medical Internet research
Association of Habitual Physical Activity With Home Blood Pressure in the Electronic Framingham Heart Study (eFHS): Cross-sectional Study.
Sardana, M., et al.
2021,  
Nature neuroscience
Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease.
Zalocusky, KA., et al.
2021,  
Scientific reports
Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration.
Zhou, L., et al.
2021,  
STAR protocols
Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons.
Li, A., et al.
2021,  
Molecular psychiatry
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.
de las Fuentes, L., et al.
2021,  
Stroke
Autonomic Imbalance and Risk of Dementia and Stroke: The Framingham Study.
Weinstein, G., et al.
2021,  
Nature communications
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
de Rojas, I., et al.
2021,  
Nature
Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy.
Da Mesquita, S., et al.
2021,  
Medical image analysis
Predicting future cognitive decline with hyperbolic stochastic coding.
Zhang, J., et al.
2021,  
Human molecular genetics
Exome sequencing revealed PDE11A as a novel candidate gene for early-onset Alzheimer's disease.
Qin, W., et al.
2021,  
JMIR mental health
Learning From Clinical Consensus Diagnosis in India to Facilitate Automatic Classification of Dementia: Machine Learning Study.
Jin, H., et al.
2021,  
Neurobiology of aging
Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population.
Marca-Ysabel, MV., et al.
2021,  
Neurobiology of aging
Genetic variants in glutamate-, Aβ-, and tau-related pathways determine polygenic risk for Alzheimer's disease.
Lawingco, T., et al.
2021,  
The journals of gerontology. Series A, Biological sciences and medical sciences
A Non-APOE Polygenic Risk Score for Alzheimer's Disease Is Associated With Cerebrospinal Fluid Neurofilament Light in a Representative Sample of Cognitively Unimpaired 70-Year Olds.
Skoog, I., et al.
2021,  
EMBO reports
Increased Alu RNA processing in Alzheimer brains is linked to gene expression changes.
Cheng, Y., et al.
2021,  
Journal of psychiatric research
Evaluation relationships between subjective wellbeing, personality traits, and Alzheimer's disease: A two-sample Mendelian randomization study.
Ma, Y., et al.
2021,  
Genome medicine
Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer's disease.
Gockley, J., et al.
2021,  
Acta neuropathologica communications
Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease.
Reddy, JS., et al.
2021,  
Communications biology
NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell data.
He, L., et al.
2021,  
Genes
A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.
Vattathil, SM., et al.
2021,  
Brain, behavior, & immunity - health
Differentially expressed genes in Alzheimer's disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1.
Li, QS.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease.
Kim, YW., et al.
2021,  
Medicinal research reviews
Artificial intelligence and machine learning-aided drug discovery in central nervous system diseases: State-of-the-arts and future directions.
Vatansever, S., et al.
2021,  
Nature aging
Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia risk.
Walker, KA., et al.
2021,  
Nature communications
Identification of putative causal loci in whole-genome sequencing data via knockoff statistics.
He, Z., et al.
2021,  
Neurology. Genetics
African Americans Have Differences in CSF Soluble TREM2 and Associated Genetic Variants.
Schindler, SE., et al.
2021,  
Proceedings. IEEE International Symposium on Biomedical Imaging
REGION SPECIFIC AUTOMATIC QUALITY ASSURANCE FOR MRI-DERIVED CORTICAL SEGMENTATIONS.
Gadewar, S., et al.
2021,  
Circulation. Genomic and precision medicine
Shared Genetic and Environmental Architecture of Cardiac Phenotypes Assessed via Echocardiography: The Framingham Heart Study.
Lin, H., et al.
2021,  
BMC bioinformatics
Modeling transcriptional regulation using gene regulatory networks based on multi-omics data sources.
Patel, N.
2021,  
Molecular psychiatry
Apolipoprotein E4 and meningeal lymphatics in Alzheimer disease: a conceptual framework.
Mentis, AA., et al.
2021,  
PLoS genetics
Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia.
Tang, S., et al.
2021,  
Proceedings of the National Academy of Sciences of the United States of America
Mendelian randomization identifies blood metabolites previously linked to midlife cognition as causal candidates in Alzheimer's disease.
Lord, J., et al.
2021,  
Translational psychiatry
Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue.
Patel, D., et al.
2021,  
Acta neuropathologica
Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer's disease in the European American population.
Kirola, L., et al.
2021,  
Scientific reports
Reconcile the debate over protective effects of BCG vaccine against COVID-19.
Fu, W., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols.
Lu, H., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols.
Wilcock, D., et al.
2021,  
Journal of neuropathology and experimental neurology
Asymmetry of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer Disease.
Proceedings of the National Academy of Sciences of the United States of America
TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau.
Ash, PEA., et al.
2021,  
Neuropsychology
Socioeconomic and psychosocial mechanisms underlying racial/ethnic disparities in cognition among older adults.
Zahodne, LB., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Long genes are more frequently affected by somatic mutations and show reduced expression in Alzheimer's disease: Implications for disease etiology.
Soheili-Nezhad, S., et al.
2021,  
American journal of human genetics
Genetic control of the human brain proteome.
Robins, C., et al.
2021,  
Scientific reports
Defining early changes in Alzheimer's disease from RNA sequencing of brain regions differentially affected by pathology.
Guennewig, B., et al.
2021,  
PLoS genetics
MOSTWAS: Multi-Omic Strategies for Transcriptome-Wide Association Studies.
Bhattacharya, A., et al.
2021,  
Genome biology
Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders.
Nabais, MF., et al.
2021,  
Genes
Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants.
Patel, D., et al.
2021,  
Genes
The Impact of Complement Genes on the Risk of Late-Onset Alzheimer's Disease.
Carpanini, SM., et al.
2021,  
Neurobiology of aging
Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-ε4 carriers.
Fulton-Howard, B., et al.
2021,  
Nature communications
Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.
Novikova, G., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL).
Granot-Hershkovitz, E., et al.
2021,  
Cerebral cortex (New York, N.Y. : 1991)
Atlas55+: Brain Functional Atlas of Resting-State Networks for Late Adulthood.
Doucet, GE., et al.
2021,  
International journal of environmental research and public health
The GGLEAM Study: Understanding Glaucoma in the Ohio Amish.
Waksmunski, AR., et al.
2021,  
Genetic epidemiology
Set-based genetic association and interaction tests for survival outcomes based on weighted V statistics.
Li, C., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Non-coding variants in MYH11, FZD3, and SORCS3 are associated with dementia in women.
Blue, EE., et al.
2021,  
Alzheimer's research & therapy
Genetically determined blood pressure, antihypertensive medications, and risk of Alzheimer's disease: a Mendelian randomization study.
Ou, Y., et al.
2021,  
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Tailor: Targeting heavy tails in flow cytometry data with fast, interpretable mixture modeling.
Ionita, M., et al.
2021,  
Translational psychiatry
Long runs of homozygosity are associated with Alzheimer's disease.
Moreno-Grau, S., et al.
2021,  
Translational psychiatry
Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease.
He, L., et al.
2021,  
Science advances
Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity.
Wahane, S., et al.
2021,  
Neurology
Association of Circulating Metabolites in Plasma or Serum and Risk of Stroke: Meta-analysis From 7 Prospective Cohorts.
Vojinovic, D., et al.
2021,  
Frontiers in radiology
Integrating Transcriptomics, Genomics, and Imaging in Alzheimer's Disease: A Federated Model.
Wu, J., et al.
2021,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Disentangled and Proportional Representation Learning for Multi-View Brain Connectomes.
Zhang, Y., et al.
2021,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Style Transfer Using Generative Adversarial Networks for Multi-Site MRI Harmonization.
Liu, M., et al.
2021,  
Journal of Alzheimer's disease : JAD
Potential Novel Genes for Late-Onset Alzheimer's Disease in East-Asian Descent Identified by APOE-Stratified Genome-Wide Association Study.
Kang, S., et al.
2021,  
Current Alzheimer research
Association of Dietary Prebiotic Consumption with Reduced Risk of Alzheimer's Disease in a Multiethnic Population.
Nishikawa, M., et al.
2021,  
Neuroepidemiology
The Association of Cognitive and Visual Function in a Nationally Representative Study of Older Adults in India.
Ehrlich, JR., et al.
2021,  
Heart & lung : the journal of critical care
Testing influences of APOE and BDNF genes and heart failure on cognitive function.
Jung, M., et al.
2021,  
NeuroImage. Clinical
A prospective cohort study of prodromal Alzheimer's disease: Prospective Imaging Study of Ageing: Genes, Brain and Behaviour (PISA).
Lupton, MK., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Polygenic risk scores for Alzheimer's disease are related to dementia risk in APOE ɛ4 negatives.
Najar, J., et al.
2021,  
Journal of Alzheimer's disease : JAD
Five-Year Change in Body Mass Index Predicts Conversion to Mild Cognitive Impairment or Dementia Only in APOE ɛ4 Allele Carriers.
Kadey, KR., et al.
2021,  
Brain communications
Defining functional variants associated with Alzheimer's disease in the induced immune response.
Harwood, JC., et al.
2021,  
Journal of neurogenetics
Analysis of whole genome sequenced cases and controls shows that the association of variants in TOMM40, BCAM, NECTIN2 and APOC1 with late onset Alzheimer's disease is driven by linkage disequilibrium with APOE ε2/ε3/ε4 alleles.
Curtis, D.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Transfer learning-trained convolutional neural networks identify novel MRI biomarkers of Alzheimer's disease progression.
Li, Y., et al.
2021,  
Frontiers in aging neuroscience
Similar Genetic Architecture of Alzheimer's Disease and Differential APOE Effect Between Sexes.
Wang, H., et al.
2021,  
Journal of Alzheimer's disease : JAD
Longitudinal Body Weight Change, Visit-To-Visit Body Weight Fluctuation, and Cognitive Decline Among Older Adults.
Lan, Y., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Causal association of cognitive reserve on Alzheimer's disease with putative sex difference.
Wang, H., et al.
2021,  
Methods in molecular biology (Clifton, N.J.)
Using INFERNO to Infer the Molecular Mechanisms Underlying Noncoding Genetic Associations.
Amlie-Wolf, A., et al.
2021,  
Alzheimer's & dementia (New York, N. Y.)
Association of neurogranin gene expression with Alzheimer's disease pathology in the perirhinal cortex.
Sun, X., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Polygenic score modifies risk for Alzheimer's disease in APOE ε4 homozygotes at phenotypic extremes.
Huq, AJ., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Cognitive screening with functional assessment improves diagnostic accuracy and attenuates bias.
González, DA., et al.
2021,  
Journal of Alzheimer's disease : JAD
Herpes Labialis, Chlamydophila pneumoniae, Helicobacter pylori, and Cytomegalovirus Infections and Risk of Dementia: The Framingham Heart Study.
Zilli, EM., et al.
2021,  
Frontiers in genetics
Copy Number Variation Identification on 3,800 Alzheimer's Disease Whole Genome Sequencing Data from the Alzheimer's Disease Sequencing Project.
Lee, W., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease.
Xue, D., et al.
2021,  
Schizophrenia bulletin
A White Matter Connection of Schizophrenia and Alzheimer's Disease.
Kochunov, P., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
The Brain Chart of Aging: Machine-learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans.
Habes, M., et al.
2021,  
Journal of the American Geriatrics Society
A Systematic Review of Delirium Biomarkers and Their Alignment with the NIA-AA Research Framework.
Wang, S., et al.
2021,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Education differentially contributes to cognitive reserve across racial/ethnic groups.
Avila, JF., et al.
2021,  
Journal of the International Neuropsychological Society : JINS
Positive Psychosocial Factors and Cognitive Decline in Ethnically Diverse Older Adults.
A Likelihood Ratio Test for Gene-Environment Interaction Based on the Trend Effect of Genotype Under an Additive Risk Model Using the Gene-Environment Independence Assumption.
de Rochemonteix, M., et al.
2021,  
Pharmacoepidemiology and drug safety
Patterns of anticonvulsant use and adverse drug events in older adults.
Moura, LMVR., et al.
2021,  
Alzheimer's research & therapy
Association between polygenic risk score of Alzheimer's disease and plasma phosphorylated tau in individuals from the Alzheimer's Disease Neuroimaging Initiative.
Zettergren, A., et al.
2021,  
BMC medicine
rs1990622 variant associates with Alzheimer's disease and regulates TMEM106B expression in human brain tissues.
Hu, Y., et al.
2021,  
Human genomics
Convergent lines of evidence support BIN1 as a risk gene of Alzheimer's disease.
Zhu, J., et al.
2021,  
Annals of neurology
Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome.
Andrews, SJ., et al.
2021,  
Neuron
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.
Wang, M., et al.
2021,  
Genome biology
The variant call format provides efficient and robust storage of GWAS summary statistics.
Lyon, MS., et al.
2021,  
Science advances
Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets.
Neff, RA., et al.
2021,  
JAMA neurology
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
Kunkle, BW., et al.
2021,  
Current neurology and neuroscience reports
Early-Onset Alzheimer's Disease: What Is Missing in Research?
Ayodele, T., et al.
2021,  
BMC microbiology
Comparison of rectal swab, glove tip, and participant-collected stool techniques for gut microbiome sampling.
Short, MI., et al.
2021,  
JAMA
Incidence of Transient Ischemic Attack and Association With Long-term Risk of Stroke.
Lioutas, V., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)
The Health & Aging Brain among Latino Elders (HABLE) study methods and participant characteristics.
O'Bryant, SE., et al.
2021,  
Dementia and geriatric cognitive disorders
Using Fractional Anisotropy Imaging to Detect Mild Cognitive Impairment and Alzheimer's Disease among Mexican Americans and Non-Hispanic Whites: A HABLE Study.
Hall, JR., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)
MRI biomarkers of small vessel disease and cognition: A cross-sectional study of a cognitively normal Mexican American cohort.
Vintimilla, R., et al.
2021,  
IEEE/ACM transactions on computational biology and bioinformatics
Multi-Task Sparse Canonical Correlation Analysis with Application to Multi-Modal Brain Imaging Genetics.
Du, L., et al.
2021,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Pattern and degree of individual brain atrophy predicts dementia onset in dominantly inherited Alzheimer's disease.
Keret, O., et al.
2021,  
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Harmonization with Flow-Based Causal Inference.
Wang, R., et al.
2020
2020,  
NeuroImage
A comparison of Freesurfer and multi-atlas MUSE for brain anatomy segmentation: Findings about size and age bias, and inter-scanner stability in multi-site aging studies.
Srinivasan, D., et al.
2020,  
BMC bioinformatics
Deep learning detection of informative features in tau PET for Alzheimer's disease classification.
Jo, T., et al.
2020,  
European journal of human genetics : EJHG
A quantitative trait rare variant nonparametric linkage method with application to age-at-onset of Alzheimer's disease.
Zhao, L., et al.
2020,  
Neurology
C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts.
Costa, B., et al.
2020,  
Journal of aging and health
Family Ties and Aging in a Multiethnic Cohort.
Ying, G., et al.
2020,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Dietary fatty acids and risk of Alzheimer's disease and related dementias: Observations from the Washington Heights-Hamilton Heights-Inwood Columbia Aging Project (WHICAP).
Gustafson, DR., et al.
2020,  
Neuromolecular medicine
Transcriptomic Heterogeneity of Alzheimer's Disease Associated with Lipid Genetic Risk.
Miao, X., et al.
2020,  
NeuroImage
Implicating causal brain imaging endophenotypes in Alzheimer's disease using multivariable IWAS and GWAS summary data.
Knutson, KA., et al.
2020,  
Brain : a journal of neurology
rs34331204 regulates TSPAN13 expression and contributes to Alzheimer's disease with sex differences.
Hu, Y., et al.
2020,  
Trends in neurosciences
Microglial Phagocytosis: A Disease-Associated Process Emerging from Alzheimer's Disease Genetics.
Podleśny-Drabiniok, A., et al.
2020,  
Science translational medicine
Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis.
Lananna, BV., et al.
2020,  
Neurology
Association of common genetic variants with brain microbleeds: A genome-wide association study.
Knol, MJ., et al.
2020,  
Nature communications
Cerebral small vessel disease genomics and its implications across the lifespan.
Sargurupremraj, M., et al.
2020,  
IEEE transactions on medical imaging
Associating Multi-Modal Brain Imaging Phenotypes and Genetic Risk Factors via a Dirty Multi-Task Learning Method.
Du, L., et al.
2020,  
Acta neuropathologica communications
Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease.
Ibanez, L., et al.
2020,  
JAMA network open
Assessment of Leisure Time Physical Activity and Brain Health in a Multiethnic Cohort of Older Adults.
Gu, Y., et al.
2020,  
Science translational medicine
Sampling interstitial fluid from human skin using a microneedle patch.
Samant, PP., et al.
2020,  
Nature communications
Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer's disease.
Zhang, L., et al.
2020,  
Molecular psychiatry
Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
Mukherjee, S., et al.
2020,  
Molecular psychiatry
Correction: Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
Mukherjee, S., et al.
2020,  
Acta neuropathologica
Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy.
Katsumata, Y., et al.
2020,  
Scientific reports
Genetic and non-genetic factors associated with the phenotype of exceptional longevity & normal cognition.
Han, B., et al.
2020,  
Nature communications
Molecular estimation of neurodegeneration pseudotime in older brains.
Mukherjee, S., et al.
2020,  
NeuroImage
Brain extraction on MRI scans in presence of diffuse glioma: Multi-institutional performance evaluation of deep learning methods and robust modality-agnostic training.
Thakur, S., et al.
2020,  
Proceedings of SPIE--the International Society for Optical Engineering
Patch-Based Surface Morphometry Feature Selection with Federated Group Lasso Regression.
Wu, J., et al.
2020,  
Proceedings. IEEE International Symposium on Bioinformatics and Bioengineering
Deep Multiview Learning to Identify Population Structure with Multimodal Imaging.
Feng, Y., et al.
2020,  
Machine learning in medical imaging. MLMI (Workshop)
A Deep Network for Joint Registration and Reconstruction of Images with Pathologies.
Han, X., et al.
2020,  
The journals of gerontology. Series A, Biological sciences and medical sciences
Parental History of Dementia Is Associated with Increased Small Vessel Cerebrovascular Disease.
Stamm, BC., et al.
2020,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
Zhao, C., et al.
2020,  
Nature
Negative feedback control of neuronal activity by microglia.
Badimon, A., et al.
2020,  
Aging cell
Underlying features of epigenetic aging clocks in vivo and in vitro.
Liu, Z., et al.
2020,  
Acta neuropathologica
ADNC-RS, a clinical-genetic risk score, predicts Alzheimer's pathology in autopsy-confirmed Parkinson's disease and Dementia with Lewy bodies.
Dai, DL., et al.
2020,  
Human molecular genetics
Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer's disease.
Morabito, S., et al.
2020,  
American journal of human genetics
Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics.
Luningham, JM., et al.
2020,  
Scientific data
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.
Sieberts, SK., et al.
2020,  
Science advances
The FAM171A2 gene is a key regulator of progranulin expression and modifies the risk of multiple neurodegenerative diseases.
Xu, W., et al.
2020,  
JAMA network open
Association of Uncommon, Noncoding Variants in the APOE Region With Risk of Alzheimer Disease in Adults of European Ancestry.
Blue, EE., et al.
2020,  
Nature genetics
An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease.
Nativio, R., et al.
2020,  
Acta neuropathologica
TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis.
Cignarella, F., et al.
2020,  
JAMA neurology
Assessment of Incidence and Risk Factors of Intracerebral Hemorrhage Among Participants in the Framingham Heart Study Between 1948 and 2016.
Lioutas, V., et al.
2020,  
Genetic epidemiology
Evaluation of population stratification adjustment using genome-wide or exonic variants.
Chen, Y., et al.
2020,  
Journal of the American Heart Association
Growth Differentiation Factor 15 and NT-proBNP as Blood-Based Markers of Vascular Brain Injury and Dementia.
McGrath, ER., et al.
2020,  
EMBO molecular medicine
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
Ewers, M., et al.
2020,  
NeuroImage
Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA.
Radua, J., et al.
2020,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease.
Lancour, D., et al.
2020,  
Hypertension (Dallas, Tex. : 1979)
Mid to Late Life Hypertension Trends and Cerebral Small Vessel Disease in the Framingham Heart Study.
Petrea, RE., et al.
2020,  
American journal of human genetics
Evolution of a Human-Specific Tandem Repeat Associated with ALS.
Course, MM., et al.
2020,  
Neurobiology of aging
Degree of genetic liability for Alzheimer's disease associated with specific proteomic profiles in cerebrospinal fluid.
Reus, LM., et al.
2020,  
Neurology
Physical activity and risk of Alzheimer disease: A 2-sample mendelian randomization study.
Baumeister, SE., et al.
2020,  
Genetic epidemiology
Fine-mapping and QTL tissue-sharing information improves the reliability of causal gene identification.
Barbeira, AN., et al.
2020,  
Neurobiology of disease
Genetic architecture of Alzheimer's disease.
Neuner, SM., et al.
2020,  
Neurobiology of disease
Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants.
Miller, JB., et al.
2020,  
Nature communications
Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture.
Zhang, Q., et al.
2020,  
Molecular and cellular biology
Endosomal Trafficking in Alzheimer's Disease, Parkinson's Disease, and Neuronal Ceroid Lipofuscinosis.
Qureshi, YH., et al.
2020,  
Cell reports
Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
Ouellette, AR., et al.
2020,  
Neurology
Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study.
Peloso, GM., et al.
2020,  
Nature communications
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults.
Hofer, E., et al.
2020,  
Journal of the American Geriatrics Society
Introduction to LASI-DAD: The Longitudinal Aging Study in India-Diagnostic Assessment of Dementia.
Lee, J.
2020,  
Journal of the American Geriatrics Society
Design and Methodology of the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (LASI-DAD).
Lee, J., et al.
2020,  
Journal of the American Geriatrics Society
Association Between Episodic Memory and Genetic Risk Factors for Alzheimer's Disease in South Asians from the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (LASI-DAD).
Smith, JA., et al.
2020,  
Genome biology
PSCAN: Spatial scan tests guided by protein structures improve complex disease gene discovery and signal variant detection.
Tang, Z., et al.
2020,  
Brain : a journal of neurology
Genetic variants and functional pathways associated with resilience to Alzheimer's disease.
Dumitrescu, L., et al.
2020,  
Clinical epigenetics
The fusiform gyrus exhibits an epigenetic signature for Alzheimer's disease.
Ma, D., et al.
2020,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways.
Sherva, R., et al.
2020,  
Neurology
Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium.
Wolters, FJ., et al.
2020,  
Molecular psychiatry
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
Bis, JC., et al.
2020,  
Neurology. Genetics
Synonymous variants associated with Alzheimer disease in multiplex families.
Tang, M., et al.
2020,  
Brain : a journal of neurology
Reply: CYLD variants in frontotemporal dementia associated with severe memory impairment in a Portuguese cohort.
Oyston, LJ., et al.
2020,  
Nature
Mapping and characterization of structural variation in 17,795 human genomes.
Abel, HJ., et al.
2020,  
Journal of the American Geriatrics Society
Interplay between Socioeconomic Markers and Polygenic Predisposition on Timing of Dementia Diagnosis.
Ajnakina, O., et al.
2020,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
MAPT haplotype-stratified GWAS reveals differential association for AD risk variants.
Strickland, SL., et al.
2020,  
Brain : a journal of neurology
Sex-dependent autosomal effects on clinical progression of Alzheimer's disease.
Fan, CC., et al.
2020,  
Molecular neurodegeneration
Deciphering cellular transcriptional alterations in Alzheimer's disease brains.
Wang, X., et al.
2020,  
Cell reports
Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.
Wan, Y., et al.
2020,  
Annals of clinical and translational neurology
Relation of plasma β-amyloid, clusterin, and tau with cerebral microbleeds: Framingham Heart Study.
Romero, JR., et al.
2020,  
Translational psychiatry
Genome-wide association study of cognitive function in diverse Hispanics/Latinos: results from the Hispanic Community Health Study/Study of Latinos.
Jian, X., et al.
2020,  
An international journal on information fusion
Autosomal Dominantly Inherited Alzheimer Disease: Analysis of genetic subgroups by Machine Learning.
Castillo-Barnes, D., et al.
2020,  
Alcohol (Fayetteville, N.Y.)
Interaction effect of alcohol consumption and Alzheimer disease polygenic risk score on the brain cortical thickness of cognitively normal subjects.
Matloff, WJ., et al.
2020,  
PLoS genetics
Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathology.
Milind, N., et al.
2020,  
Bioinformatics (Oxford, England)
SparkINFERNO: a scalable high-throughput pipeline for inferring molecular mechanisms of non-coding genetic variants.
Kuksa, PP., et al.
2020,  
Neurobiology of disease
Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2.
Hsu, S., et al.
2020,  
Acta neuropathologica
rs4147929 variant minor allele increases ABCA7 gene expression and ABCA7 shows increased gene expression in Alzheimer's disease patients compared with controls.
Liu, G., et al.
2020,  
Neurobiology of aging
Failure to detect synergy between variants in transferrin and hemochromatosis and Alzheimer's disease in large cohort.
Vance, E., et al.
2020,  
Nature medicine
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
Johnson, ECB., et al.
2020,  
Diabetologia
Neurocognitive impairment in type 2 diabetes: evidence for shared genetic aetiology.
Mollon, J., et al.
2020,  
Nutrients
Proteomic and Metabolomic Correlates of Healthy Dietary Patterns: The Framingham Heart Study.
Walker, ME., et al.
2020,  
The Journal of nervous and mental disease
A Critical Review of Behavioral and Emotional Disinhibition.
Huey, ED.
2020,  
Alzheimer's research & therapy
An analysis of genetically regulated gene expression across multiple tissues implicates novel gene candidates in Alzheimer's disease.
Gerring, ZF., et al.
2020,  
Nature communications
Accurate estimation of cell composition in bulk expression through robust integration of single-cell information.
Jew, B., et al.
2020,  
The Lancet. Neurology
Interpretation of risk loci from genome-wide association studies of Alzheimer's disease.
Andrews, SJ., et al.
2020,  
Neurology. Genetics
Use of local genetic ancestry to assess TOMM40-523' and risk for Alzheimer disease.
Bussies, PL., et al.
2020,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease.
Elahi, FM., et al.
2020,  
Obesity reviews : an official journal of the International Association for the Study of Obesity
Association of anthropometry and weight change with risk of dementia and its major subtypes: A meta-analysis consisting 2.8 million adults with 57 294 cases of dementia.
Lee, CM., et al.
2020,  
Neuron
Human Herpesvirus 6 Detection in Alzheimer's Disease Cases and Controls across Multiple Cohorts.
Allnutt, MA., et al.
2020,  
Translational psychiatry
Shared genetic etiology underlying Alzheimer's disease and major depressive disorder.
Lutz, MW., et al.
2020,  
Cerebral cortex (New York, N.Y. : 1991)
Corticosteroids and Regional Variations in Thickness of the Human Cerebral Cortex across the Lifespan.
Parker, N., et al.
2020,  
Science (New York, N.Y.)
The genetic architecture of the human cerebral cortex.
Grasby, KL., et al.
2020,  
Current opinion in immunology
Innate sensing of mechanical properties of brain tissue by microglia.
Ayata, P.
2020,  
Proceedings of the National Academy of Sciences of the United States of America
De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Kessler, MD., et al.
2020,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Association between alcohol consumption and Alzheimer's disease: A Mendelian randomization study.
Andrews, SJ., et al.
2020,  
Acta neuropathologica
Overlapping genetic architecture between Parkinson disease and melanoma.
Dube, U., et al.
2020,  
Nature communications
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
Reiman, EM., et al.
2020,  
Science translational medicine
APOE genotype regulates pathology and disease progression in synucleinopathy.
Davis, AA., et al.
2020,  
The journals of gerontology. Series A, Biological sciences and medical sciences
Epigenetic Age Acceleration and Cognitive Function in African American Adults in Midlife: The Atherosclerosis Risk in Communities Study.
Bressler, J., et al.
2020,  
Annals of clinical and translational neurology
Circulating ceramide ratios and risk of vascular brain aging and dementia.
McGrath, ER., et al.
2020,  
Neuropsychology
Linking depressive symptoms and cognitive functioning: The mediating role of leisure activity.
Sharifian, N., et al.
2020,  
Genetic epidemiology
Case-control versus case-only estimates of gene-environment interactions with common and misclassified clinical diagnosis.
Lobach, I., et al.
2020,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer.
Pathak, GA., et al.
2020,  
Acta neuropathologica
The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion.
Li, Z., et al.
2020,  
The Lancet. Neurology
Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies.
Ding, J., et al.
2020,  
Neurology
Association of CD14 with incident dementia and markers of brain aging and injury.
Pase, MP., et al.
2020,  
Journal of neuropathology and experimental neurology
Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene.
Katsumata, Y., et al.
2020,  
Journal of Alzheimer's disease : JAD
Neurofilament Light Predicts Decline in Attention but Not Episodic Memory in Preclinical Alzheimer's Disease.
Aschenbrenner, AJ., et al.
2020,  
The Journal of neuropsychiatry and clinical neurosciences
Effect of Functional BDNF and COMT Polymorphisms on Symptoms and Regional Brain Volume in Frontotemporal Dementia and Corticobasal Syndrome.
Huey, ED., et al.
2020,  
Journal of Alzheimer's disease : JAD
CCL23: A Chemokine Associated with Progression from Mild Cognitive Impairment to Alzheimer's Disease.
Faura, J., et al.
2020,  
Alzheimer disease and associated disorders
Physical Exercise and Longitudinal Trajectories in Alzheimer Disease Biomarkers and Cognitive Functioning.
Stojanovic, M., et al.
2020,  
Alzheimer's & dementia (New York, N. Y.)
Differences in plasma metabolites related to Alzheimer's disease, APOE ε4 status, and ethnicity.
Vardarajan, B., et al.
2020,  
Alzheimer's & dementia (Amsterdam, Netherlands)
APOE ε4 and resting-state functional connectivity in racially/ethnically diverse older adults.
Turney, IC., et al.
2020,  
Immunity & ageing : I & A
Reproducibility of serum cytokines in an elderly population.
Guo, J., et al.
2020,  
Biodemography and social biology
Methodological considerations in designing and implementing the harmonized diagnostic assessment of dementia for longitudinal aging study in India (LASI-DAD).
Banerjee, J., et al.
2020,  
Journal of Alzheimer's disease : JAD
Circulating Vitamin D Levels and Alzheimer's Disease: A Mendelian Randomization Study in the IGAP and UK Biobank.
Wang, L., et al.
2020,  
Journal of Alzheimer's disease : JAD
Impact of Vitamin D Binding Protein Levels on Alzheimer's Disease: A Mendelian Randomization Study.
Zhang, H., et al.
2020,  
Journal of Alzheimer's disease : JAD
Impact of Serum Calcium Levels on Alzheimer's Disease: A Mendelian Randomization Study.
He, Y., et al.
2020,  
PloS one
Identification of functionally connected multi-omic biomarkers for Alzheimer's disease using modularity-constrained Lasso.
Xie, L., et al.
2020,  
Journal of Alzheimer's disease : JAD
Characterizing Clinical and Neuropathological Traits of APOE Haplotypes in African Americans and Europeans.
Mezlini, AM., et al.
2020,  
PloS one
Quantifying cognitive resilience in Alzheimer's Disease: The Alzheimer's Disease Cognitive Resilience Score.
Yao, T., et al.
2020,  
Journal of Alzheimer's disease : JAD
Investigating Causal Relations Between Risk Tolerance, Risky Behaviors, and Alzheimer's Disease: A Bidirectional Two-Sample Mendelian Randomization Study.
Yang, Y., et al.
2020,  
Frontiers in aging neuroscience
Association of Genes Involved in the Metabolic Pathways of Amyloid-β and Tau Proteins With Sporadic Late-Onset Alzheimer's Disease in the Southern Han Chinese Population.
Xiao, X., et al.
2020,  
Frontiers in genetics
Recent Consanguinity and Outbred Autozygosity Are Associated With Increased Risk of Late-Onset Alzheimer's Disease.
Napolioni, V., et al.
2020,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Packaging Biocomputing Software to Maximize Distribution and Reuse.
Bush, WS., et al.
2020,  
Computational and structural biotechnology journal
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Hadoop and PySpark for reproducibility and scalability of genomic sequencing studies.
Wheeler, NR., et al.
2020,  
Journal of Alzheimer's disease : JAD
Immune and Inflammatory Pathways Implicated by Whole Blood Transcriptomic Analysis in a Diverse Ancestry Alzheimer's Disease Cohort.
Griswold, AJ., et al.
2020,  
PloS one
An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury.
Altendahl, M., et al.
2020,  
Brain communications
The genetics of circulating BDNF: towards understanding the role of BDNF in brain structure and function in middle and old ages.
Li, S., et al.
2020,  
Journal of Alzheimer's disease : JAD
Whole-Exome Sequencing Analysis of Alzheimer's Disease in Non-APOE*4 Carriers.
Fan, K., et al.
2020,  
Journal of Alzheimer's disease : JAD
Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD Through Multiple Phenotypes.
Olive, C., et al.
2019
2019,  
Neurobiology of aging
Identification of genetic heterogeneity of Alzheimer's disease across age.
Lo, M., et al.
2019,  
International journal of epidemiology
Polygenic risk scores for Alzheimer's disease, and academic achievement, cognitive and behavioural measures in children from the general population.
Korologou-Linden, R., et al.
2019,  
BMC bioinformatics
Benchmarking machine learning models for late-onset alzheimer's disease prediction from genomic data.
De Velasco Oriol, J., et al.
2019,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration.
Smith, EE., et al.
2019,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Full exploitation of high dimensionality in brain imaging: The JPND working group statement and findings.
Adams, HHH., et al.
2019,  
Alzheimer's & dementia (Amsterdam, Netherlands)
The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: Design and multicenter pilot study.
Weaver, NA., et al.
2019,  
Stroke
Response by Aparicio et al to Letter Regarding Article, "Temporal Trends in Ischemic Stroke Incidence in Younger Adults in the Framingham Study".
Aparicio, HJ., et al.
2019,  
Annals of clinical and translational neurology
Mid-life and late-life vascular risk factor burden and neuropathology in old age.
Conner, SC., et al.
2019,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).
González, HM., et al.
2019,  
Alzheimer's research & therapy
APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain.
Lefterov, I., et al.
2019,  
Brain : a journal of neurology
Rs2293871 regulates HTRA1 expression and affects cerebral small vessel stroke and Alzheimer's disease.
Liu, G., et al.
2019,  
Scientific reports
Genome Wide Meta-Analysis identifies common genetic signatures shared by heart function and Alzheimer's disease.
Sáez, ME., et al.
2019,  
Nature neuroscience
An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations.
Dube, U., et al.
2019,  
Environment international
Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation.
Gondalia, R., et al.
2019,  
Nature genetics
Genetic architecture of subcortical brain structures in 38,851 individuals.
Satizabal, CL., et al.
2019,  
American journal of human genetics
A Rare Variant Nonparametric Linkage Method for Nuclear and Extended Pedigrees with Application to Late-Onset Alzheimer Disease via WGS Data.
Zhao, L., et al.
2019,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
Moreno-Grau, S., et al.
2019,  
Translational psychiatry
Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease.
Creese, B., et al.
2019,  
BMC cardiovascular disorders
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.
Schmidt, AF., et al.
2019,  
Neuroscience letters
Promoter DNA hypermethylation - Implications for Alzheimer's disease.
Liu, Y., et al.
2019,  
Human molecular genetics
RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways.
Gardner, OK., et al.
2019,  
Journal of the American Geriatrics Society
White Matter Hyperintensities and Hippocampal Atrophy in Relation to Cognition: The 90+ Study.
Legdeur, N., et al.
2019,  
Liver international : official journal of the International Association for the Study of the Liver
Non-alcoholic fatty liver disease, liver fibrosis score and cognitive function in middle-aged adults: The Framingham Study.
Weinstein, G., et al.
2019,  
Annals of neurology
Plasma total-tau as a biomarker of stroke risk in the community.
Pase, MP., et al.
2019,  
Annals of clinical and translational neurology
Circulating IGFBP-2: a novel biomarker for incident dementia.
McGrath, ER., et al.
2019,  
Circulation research
Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals.
Georgakis, MK., et al.
2019,  
Brain : a journal of neurology
Sex differences in the genetic predictors of Alzheimer's pathology.
Dumitrescu, L., et al.
2019,  
JAMA neurology
Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.
Ma, Y., et al.
2019,  
Alzheimer's research & therapy
A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain.
Del-Aguila, JL., et al.
2019,  
Science translational medicine
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk.
Deming, Y., et al.
2019,  
Science translational medicine
Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease.
Ewers, M., et al.
2019,  
JAMA neurology
Association of Variants in PINX1 and TREM2 With Late-Onset Alzheimer Disease.
Tosto, G., et al.
2019,  
Aging cell
CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
Ma, Y., et al.
2019,  
American journal of human genetics
TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits.
Nagpal, S., et al.
2019,  
Journal of clinical medicine
APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer's Disease Risk in a Multiracial Sample.
Choi, KY., et al.
2019,  
Science advances
Epigenetic signatures of methylated DNA cytosine in Alzheimer's disease.
Fetahu, IS., et al.
2019,  
Cell reports
cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis.
Ojelade, SA., et al.
2019,  
Circulation
Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease.
Agha, G., et al.
2019,  
Genetic epidemiology
A simple approximation to bias in the genetic effect estimates when multiple disease states share a clinical diagnosis.
Lobach, I., et al.
2019,  
Neurobiology of disease
Heritability and genetic variance of dementia with Lewy bodies.
Guerreiro, R., et al.
2019,  
Nature communications
A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration.
Handa, JT., et al.
2019,  
Journal of the American Heart Association
Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes.
Vasan, RS., et al.
2019,  
Genomics
Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project.
Naj, AC., et al.
2019,  
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Neurotherapeutics of the Aging Brain: Complexity Meets Complexity.
Lerner, AJ.
2019,  
Acta neuropathologica
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.
Pottier, C., et al.
2019,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Novel methods for integration and visualization of genomics and genetics data in Alzheimer's disease.
Bihlmeyer, NA., et al.
2019,  
European journal of epidemiology
Blood-brain barrier transcytosis genes, risk of dementia and stroke: a prospective cohort study of 74,754 individuals.
Juul Rasmussen, I., et al.
2019,  
Current protocols in human genetics
Genotype Imputation in Genome-Wide Association Studies.
Naj, AC.
2019,  
The Journal of neuroscience : the official journal of the Society for Neuroscience
PTCD1 Is Required for Mitochondrial Oxidative-Phosphorylation: Possible Genetic Association with Alzheimer's Disease.
Fleck, D., et al.
2019,  
Molecular neurodegeneration
TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers.
Del-Aguila, JL., et al.
2019,  
European journal of human genetics : EJHG
Comparison of methods for multivariate gene-based association tests for complex diseases using common variants.
Chung, J., et al.
2019,  
Nature communications
Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer's disease pathology and cognitive symptoms.
Li, P., et al.
2019,  
Translational psychiatry
Alzheimer's disease polygenic risk score as a predictor of conversion from mild-cognitive impairment.
Chaudhury, S., et al.
2019,  
Bioinformatics (Oxford, England)
VCPA: genomic variant calling pipeline and data management tool for Alzheimer's Disease Sequencing Project.
Leung, YY., et al.
2019,  
Neurology
Cerebral white matter free water: A sensitive biomarker of cognition and function.
Maillard, P., et al.
2019,  
JAMA neurology
Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes.
Pase, MP., et al.
2019,  
Nature communications
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
Davies, G., et al.
2019,  
BMJ (Clinical research ed.)
Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study.
Carter, AR., et al.
2019,  
Genome biology
Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight.
Ebbert, MTW., et al.
2019,  
Neurology. Genetics
Genomic variation in educational attainment modifies Alzheimer disease risk.
Raghavan, NS., et al.
2019,  
Medical care
Epilepsy Among Elderly Medicare Beneficiaries: A Validated Approach to Identify Prevalent and Incident Epilepsy.
Moura, LMVR., et al.
2019,  
Nature genetics
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.
Huckins, LM., et al.
2019,  
Neurology
A prospective study of serum metabolites and risk of ischemic stroke.
Sun, D., et al.
2019,  
BMJ (Clinical research ed.)
Physical inactivity, cardiometabolic disease, and risk of dementia: an individual-participant meta-analysis.
Kivimäki, M., et al.
2019,  
JAMA network open
Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study.
Spartano, NL., et al.
2019,  
Brain : a journal of neurology
Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects.
Mishra, A., et al.
2019,  
Neurology
Education and cognitive reserve in old age.
Wilson, RS., et al.
2019,  
Current genetic medicine reports
GWAS and Beyond: Using Omics Approaches to Interpret SNP Associations.
Chen, H., et al.
2019,  
Epilepsy research
Medicare claims can identify post-stroke epilepsy.
Moura, LMVR., et al.
2019,  
Nature genetics
A statistical framework for cross-tissue transcriptome-wide association analysis.
Hu, Y., et al.
2019,  
Current genetic medicine reports
Protective Variants in Alzheimer's Disease.
Andrews, SJ., et al.
2019,  
Neurology
Distribution of cerebral microbleeds in the East and West: Individual participant meta-analysis.
Yakushiji, Y., et al.
2019,  
Nature genetics
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Kunkle, BW., et al.
2019,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease.
Zhang, X., et al.
2019,  
Bioinformatics (Oxford, England)
DASHR 2.0: integrated database of human small non-coding RNA genes and mature products.
Kuksa, PP., et al.
2019,  
JAMA network open
Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry.
Patel, D., et al.
2019,  
Translational psychiatry
Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism.
Kapoor, M., et al.
2019,  
Neurology
Postmortem neurodegenerative markers and trajectories of decline in cognitive systems.
Wilson, RS., et al.
2019,  
Neuropathology and applied neurobiology
Is APOE ε4 required for Alzheimer's disease to develop in TREM2 p.R47H variant carriers?
Guerreiro, R., et al.
2019,  
Acta neuropathologica
Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.
Broce, IJ., et al.
2019,  
American journal of epidemiology
Trajectories of Nonagenarian Health: Sex, Age, and Period Effects.
Odden, MC., et al.
2019,  
Blood
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
de Vries, PS., et al.
2019,  
Neurology
The emerging genetic landscape of cerebral white matter hyperintensities.
Fornage, M.
2019,  
Neurobiology of aging
Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs.
Katsumata, Y., et al.
2019,  
Molecular neurodegeneration
Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology.
Suárez-Calvet, M., et al.
2019,  
The American journal of clinical nutrition
Circulating antioxidants and Alzheimer disease prevention: a Mendelian randomization study.
Williams, DM., et al.
2019,  
Nature genetics
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
Giri, A., et al.
2019,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Vascular dysfunction-The disregarded partner of Alzheimer's disease.
Sweeney, MD., et al.
2019,  
Briefings in bioinformatics
Association score testing for rare variants and binary traits in family data with shared controls.
Saad, M.
2019,  
Circulation
Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.
Sabater-Lleal, M., et al.
2019,  
Neurology
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.
Chauhan, G., et al.
2019,  
Wellcome open research
Guidelines for performing Mendelian randomization investigations: update for summer 2023.
Burgess, S., et al.
2019,  
Frontiers in neuroscience
Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes.
Drange, OK., et al.
2019,  
Frontiers in genetics
Polygenic Risk Score for Alzheimer's Disease Is Associated With Ch4 Volume in Normal Subjects.
Wang, T., et al.
2019,  
Frontiers in genetics
A Simple Approximation to Bias in Gene-Environment Interaction Estimates When a Case Might Not Be the Case.
Lobach, I., et al.
2019,  
Frontiers in neurology
A Machine Learning Method for Identifying Critical Interactions Between Gene Pairs in Alzheimer's Disease Prediction.
Chen, H., et al.
2019,  
Wellcome open research
Polygenic risk score for Alzheimer's disease and trajectories of cardiometabolic risk factors in children.
Korologou-Linden, R., et al.
2019,  
Frontiers in genetics
eQTLMAPT: Fast and Accurate eQTL Mediation Analysis With Efficient Permutation Testing Approaches.
Wang, T., et al.
2019,  
Clinical interventions in aging
RAB10: an Alzheimer's disease resilience locus and potential drug target.
Tavana, JP., et al.
2019,  
Alzheimer disease and associated disorders
Birth in High Infant Mortality States and Dementia Risk in a Cohort of Elderly African American and White Health Care Members.
Gilsanz, P., et al.
2019,  
Journal of diabetes research
Self-Reported Physical Activity and Relations to Growth and Neurotrophic Factors in Diabetes Mellitus: The Framingham Offspring Study.
Spartano, NL., et al.
2019,  
PloS one
Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts.
Weinstein, G., et al.
2019,  
Journal of Alzheimer's disease : JAD
Vascular Burden Score Impacts Cognition Independent of Amyloid PET and MRI Measures of Alzheimer's Disease and Vascular Brain Injury.
DeCarli, C., et al.
2019,  
PloS one
Whole blood microRNA expression associated with stroke: Results from the Framingham Heart Study.
Salinas, J., et al.
2019,  
Alzheimer's & dementia (New York, N. Y.)
Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study.
Spartano, NL., et al.
2019,  
Journal of Alzheimer's disease : JAD
Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts.
Conner, SC., et al.
2019,  
PloS one
Circulating fibroblast growth factor 23 levels and incident dementia: The Framingham heart study.
McGrath, ER., et al.
2019,  
PloS one
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.
Baker, E., et al.
2019,  
PloS one
The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE).
Wolters, FJ., et al.
2019,  
Communications biology
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.
van der Lee, SJ., et al.
2019,  
Journal of Alzheimer's disease : JAD
Inferring the Molecular Mechanisms of Noncoding Alzheimer's Disease-Associated Genetic Variants.
Amlie-Wolf, A., et al.
2019,  
Alzheimer's & dementia (New York, N. Y.)
Estrogen activates Alzheimer's disease genes.
Ratnakumar, A., et al.
2018
2018,  
EMBO molecular medicine
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
Suárez-Calvet, M., et al.
2018,  
Neurobiology of aging
Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease.
Gusareva, ES., et al.
2018,  
Genetic epidemiology
Bias in parameter estimates due to omitting gene-environment interaction terms in case-control studies.
Lobach, I.
2018,  
Molecular neurodegeneration
Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.
Wang, H., et al.
2018,  
Scientific reports
Meta-analysis of Alzheimer's disease on 9,751 samples from Norway and IGAP study identifies four risk loci.
Witoelar, A., et al.
2018,  
Aging medicine (Milton (N.S.W))
Systemic inflammation and causal risk for Alzheimer's dementia: Possibilities and limitations of a Mendelian randomization approach.
Tsui, A.
2018,  
Translational psychiatry
Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP.
Jiang, S., et al.
2018,  
PLoS genetics
Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.
Rajabli, F., et al.
2018,  
Acta neuropathologica
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
Deming, Y., et al.
2018,  
Nature communications
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.
Franceschini, N., et al.
2018,  
Neurobiology of aging
Cerebral tract integrity relates to white matter hyperintensities, cortex volume, and cognition.
Seiler, S., et al.
2018,  
Stroke
APOE and the Association of Fatty Acids With the Risk of Stroke, Coronary Heart Disease, and Mortality.
Satizabal, CL., et al.
2018,  
Neurology. Genetics
Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease.
Beecham, GW., et al.
2018,  
Scientific reports
Systematic Analysis and Biomarker Study for Alzheimer's Disease.
Li, X., et al.
2018,  
American journal of human genetics
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
Ligthart, S., et al.
2018,  
Molecular psychiatry
Meta-analysis of epigenome-wide association studies of cognitive abilities.
Marioni, RE., et al.
2018,  
Neurology
Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study.
Echouffo-Tcheugui, JB., et al.
2018,  
JAMA network open
Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers.
Tao, Q., et al.
2018,  
Neurology
Vascular risk at younger ages most strongly associates with current and future brain volume.
Pase, MP., et al.
2018,  
Physiological genomics
GNAI2 polymorphic variance associates with salt sensitivity of blood pressure in the Genetic Epidemiology Network of Salt Sensitivity study.
Zhang, X., et al.
2018,  
Nucleic acids research
INFERNO: inferring the molecular mechanisms of noncoding genetic variants.
Amlie-Wolf, A., et al.
2018,  
Bioinformatics (Oxford, England)
EMUDRA: Ensemble of Multiple Drug Repositioning Approaches to improve prediction accuracy.
Zhou, X., et al.
2018,  
Scientific data
The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.
Wang, M., et al.
2018,  
Genetic epidemiology
Analysis of pedigree data in populations with multiple ancestries: Strategies for dealing with admixture in Caribbean Hispanic families from the ADSP.
Nafikov, RA., et al.
2018,  
JAMA psychiatry
DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies.
Story Jovanova, O., et al.
2018,  
Nature communications
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.
Vojinovic, D., et al.
2018,  
Stroke
Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults.
Raman, MR., et al.
2018,  
Neuropathology and applied neurobiology
Whole-exome sequencing of the BDR cohort: evidence to support the role of the PILRA gene in Alzheimer's disease.
Patel, T., et al.
2018,  
JAMA neurology
Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.
Hohman, TJ., et al.
2018,  
Nature neuroscience
Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome.
Girdhar, K., et al.
2018,  
Stroke
Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.
Jian, X., et al.
2018,  
The Lancet. Neurology
Top research priorities for stroke genetics.
Woo, D., et al.
2018,  
Bioinformatics (Oxford, England)
Functional annotation of genomic variants in studies of late-onset Alzheimer's disease.
Butkiewicz, M., et al.
2018,  
Expert opinion on therapeutic targets
Triggering receptor expressed on myeloid cells 2 (TREM2): a potential therapeutic target for Alzheimer disease?
Deming, Y., et al.
2018,  
Nucleic acids research
SPAR: small RNA-seq portal for analysis of sequencing experiments.
Kuksa, PP., et al.
2018,  
JAMA neurology
Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum.
Karch, CM., et al.
2018,  
Neuron
Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.
Readhead, B., et al.
2018,  
International journal of stroke : official journal of the International Stroke Society
Clinical significance of cerebral microbleeds on MRI: A comprehensive meta-analysis of risk of intracerebral hemorrhage, ischemic stroke, mortality, and dementia in cohort studies (v1).
Charidimou, A., et al.
2018,  
Genes, brain, and behavior
Variants regulating ZBTB4 are associated with age-at-onset of Alzheimer's disease.
Blue, EE., et al.
2018,  
Bioinformatics (Oxford, England)
Integrative DNA copy number detection and genotyping from sequencing and array-based platforms.
Zhou, Z., et al.
2018,  
Annals of clinical and translational neurology
Whole-exome sequencing in 20,197 persons for rare variants in Alzheimer's disease.
Raghavan, NS., et al.
2018,  
Experimental gerontology
Genetically elevated gamma-glutamyltransferase and Alzheimer's disease.
Kunutsor, SK., et al.
2018,  
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology
Tau Phosphorylation is Impacted by Rare AKAP9 Mutations Associated with Alzheimer Disease in African Americans.
Ikezu, T., et al.
2018,  
Stroke
Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia.
Rutten-Jacobs, LCA., et al.
2018,  
American journal of human genetics
Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS.
Dobbyn, A., et al.
2018,  
Scientific reports
Brain Cell Type Specific Gene Expression and Co-expression Network Architectures.
McKenzie, AT., et al.
2018,  
Cell reports
Tau Activates Transposable Elements in Alzheimer's Disease.
Guo, C., et al.
2018,  
Preventive medicine
Vascular risk factor burden and new-onset depression in the community.
Adams, S., et al.
2018,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts.
Tynkkynen, J., et al.
2018,  
Stroke
Imaging Endophenotypes of Stroke as a Target for Genetic Studies.
Jian, X.
2018,  
Science (New York, N.Y.)
Analysis of shared heritability in common disorders of the brain.
Anttila, V., et al.
2018,  
Scientific reports
Sex Differences in Cognitive Decline in Subjects with High Likelihood of Mild Cognitive Impairment due to Alzheimer's disease.
Sohn, D., et al.
2018,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.
Chung, J., et al.
2018,  
Human molecular genetics
Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.
Teslovich, TM., et al.
2018,  
Translational psychiatry
GWAS on family history of Alzheimer's disease.
Marioni, RE., et al.
2018,  
Bioinformatics (Oxford, England)
GIGI-Quick: a fast approach to impute missing genotypes in genome-wide association family data.
Kunji, K., et al.
2018,  
Nature communications
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
Davies, G., et al.
2018,  
Current genomics
Retromer Dysfunction and Neurodegenerative Disease.
Reitz, C.
2018,  
Molecular psychiatry
Genetic risk for schizophrenia and psychosis in Alzheimer disease.
DeMichele-Sweet, MAA., et al.
2018,  
PLoS genetics
One for all and all for One: Improving replication of genetic studies through network diffusion.
Lancour, D., et al.
2018,  
Nature genetics
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Malik, R., et al.
2018,  
The journals of gerontology. Series B, Psychological sciences and social sciences
Are Trends in Dementia Incidence Associated With Compression in Morbidity? Evidence From The Framingham Heart Study.
Dufouil, C., et al.
2018,  
Annals of clinical and translational neurology
Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.
Vardarajan, BN., et al.
2018,  
BMC medicine
Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: cohort studies and meta-analyses of 362,338 individuals.
Nordestgaard, LT., et al.
2018,  
American journal of human genetics
Comprehensive Analysis of Constraint on the Spatial Distribution of Missense Variants in Human Protein Structures.
Sivley, RM., et al.
2018,  
Genome medicine
Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models.
Sekiya, M., et al.
2018,  
Annals of human genetics
Fast permutation tests and related methods, for association between rare variants and binary outcomes.
Sondhi, A.
2018,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms.
Cruchaga, C., et al.
2018,  
American journal of Alzheimer's disease and other dementias
Val66Met Polymorphism in BDNF Has No Sexual and APOE ε4 Status-Based Dimorphic Effects on Susceptibility to Alzheimer's Disease: Evidence From an Updated Meta-Analysis of Case-Control Studies and High-Throughput Genotyping Cohorts.
Zhao, Q., et al.
2018,  
Neurobiology of aging
Genetic influence of plasma homocysteine on Alzheimer's disease.
Roostaei, T., et al.
2018,  
Neurobiology of aging
Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer's disease.
Chaudhury, S., et al.
2018,  
Proceedings of the National Academy of Sciences of the United States of America
Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease.
Bennett, RE., et al.
2018,  
Proceedings of the National Academy of Sciences of the United States of America
Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer's disease pathogenesis.
Zhou, X., et al.
2018,  
Alzheimer's research & therapy
Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease.
Chung, J., et al.
2018,  
Biological psychiatry
Untangling Genetic Risk for Alzheimer's Disease.
Pimenova, AA., et al.
2018,  
Gastroenterology
Exome-Wide Association Study of Pancreatic Cancer Risk.
Grant, RC., et al.
2018,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial magnetic resonance imaging study.
Kinnunen, KM., et al.
2018,  
Neurobiology of aging
Age and the association of dementia-related pathology with trajectories of cognitive decline.
Jansen, WJ., et al.
2018,  
Acta neuropathologica
Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.
Tan, CH., et al.
2018,  
Neurology
Circulating insulin-like growth factors and Alzheimer disease: A mendelian randomization study.
Williams, DM., et al.
2018,  
The Lancet. Neurology
The genetic architecture of dementia with Lewy bodies is shaping up.
Fornage, M.
2018,  
Neurology
Whole genome sequence analyses of brain imaging measures in the Framingham Study.
Sarnowski, C., et al.
2018,  
Journal of Alzheimer's disease : JAD
Cerebrovascular Disease and Neurodegeneration in Alzheimer's Disease with and without a Strong Family History: A Pilot Magnetic Resonance Imaging Study in Dominican Republic.
Piriz, A., et al.
2018,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Topographic staging of tau positron emission tomography images.
Schwarz, AJ., et al.
2018,  
Journal of Alzheimer's disease : JAD
The GWAS Risk Genes for Depression May Be Actively Involved in Alzheimer's Disease.
Ni, H., et al.
2018,  
PloS one
Case-control studies of gene-environment interactions. When a case might not be the case.
Lobach, I., et al.
2018,  
Frontiers in neuroscience
Targeted Sequencing of Alzheimer Disease Genes in African Americans Implicates Novel Risk Variants.
Logue, MW., et al.
2018,  
BMC proceedings
An efficient analytic approach in genome-wide identification of methylation quantitative trait loci response to fenofibrate treatment.
Cox, JW., et al.
2018,  
PloS one
Episodic memory performance in a multi-ethnic longitudinal study of 13,037 elderly.
Lee, S., et al.
2018,  
Frontiers in neuroscience
Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease.
Fernández, MV., et al.
2018,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Local ancestry transitions modify snp-trait associations.
Fish, AE., et al.
2018,  
PloS one
Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke.
Cole, JW., et al.
2018,  
Journal of Alzheimer's disease : JAD
Genetic Interaction with Plasma Lipids on Alzheimer's Disease in the Framingham Heart Study.
Peloso, GM., et al.
2018,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.
Peloso, GM., et al.
2018,  
Dementia and geriatric cognitive disorders
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.
Blue, EE., et al.
2017
2017,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study.
Chouraki, V., et al.
2017,  
Neurology
Blood pressure from mid- to late life and risk of incident dementia.
McGrath, ER., et al.
2017,  
Neurology
Alzheimer disease brain atrophy subtypes are associated with cognition and rate of decline.
Risacher, SL., et al.
2017,  
eLife
Neuropathological and transcriptomic characteristics of the aged brain.
Miller, JA., et al.
2017,  
Molecular neurodegeneration
Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease.
McKenzie, AT., et al.
2017,  
Genome medicine
Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience.
Ridge, PG., et al.
2017,  
PLoS genetics
Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease.
Fernández, MV., et al.
2017,  
JAMA neurology
Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis.
Neu, SC., et al.
2017,  
Genome biology
McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genes.
Hafez, D., et al.
2017,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Systems biology approach to late-onset Alzheimer's disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments.
Mukherjee, S., et al.
2017,  
Human genetics
Investigating the genetic relationship between Alzheimer's disease and cancer using GWAS summary statistics.
Feng, YA., et al.
2017,  
Scientific reports
Branched-chain amino acids and Alzheimer's disease: a Mendelian randomization analysis.
Larsson, SC.
2017,  
European journal of epidemiology
Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium.
Chibnik, LB., et al.
2017,  
Neurology. Genetics
The Alzheimer's Disease Sequencing Project: Study design and sample selection.
Beecham, GW., et al.
2017,  
JAMA neurology
Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport.
Kunkle, BW., et al.
2017,  
Annals of neurology
Polygenic hazard scores in preclinical Alzheimer disease.
Tan, CH., et al.
2017,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Sugary beverage intake and preclinical Alzheimer's disease in the community.
Pase, MP., et al.
2017,  
Nature genetics
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Sims, R., et al.
2017,  
Stroke
Response by Pase et al to Letter Regarding Article, "Sweetened Beverages and the Risks of Incident Stroke and Dementia".
Pase, MP., et al.
2017,  
Neurology
Sleep architecture and the risk of incident dementia in the community.
Pase, MP., et al.
2017,  
Molecular neurodegeneration
Whole blood gene expression and white matter Hyperintensities.
Lin, H., et al.
2017,  
Journal of Alzheimer's disease & Parkinsonism
Exome Sequencing of Extended Families with Alzheimer's Disease Identifies Novel Genes Implicated in Cell Immunity and Neuronal Function.
Cukier, HN., et al.
2017,  
Nature neuroscience
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.
Huang, K., et al.
2017,  
Neurology
Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes: Mendelian randomization study.
Larsson, SC., et al.
2017,  
Biological psychiatry
The Schizophrenia-Associated BRD1 Gene Regulates Behavior, Neurotransmission, and Expression of Schizophrenia Risk Enriched Gene Sets in Mice.
Qvist, P., et al.
2017,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
The Journal of clinical endocrinology and metabolism
Body Mass Index and Risk of Alzheimer's Disease: A Mendelian Randomization Study of 399,536 Individuals.
Nordestgaard, LT., et al.
2017,  
Stroke
Response by Pase et al to Letters Regarding Article, "Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia. A Prospective Cohort Study".
Pase, MP., et al.
2017,  
Stroke
Response by Pase et al to Letter Regarding Article, "Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study".
Pase, MP., et al.
2017,  
Stroke
Role of Improved Vascular Health in the Declining Incidence of Dementia.
Pase, MP., et al.
2017,  
Acta neuropathologica
Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.
Chapuis, J., et al.
2017,  
Acta neuropathologica
Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.
Deming, Y., et al.
2017,  
Translational psychiatry
Genetic susceptibility to cardiovascular disease and risk of dementia.
Karlsson, IK., et al.
2017,  
Molecular neurodegeneration
Late onset Alzheimer's disease genetics implicates microglial pathways in disease risk.
Efthymiou, AG.
2017,  
Neuroscience letters
Targeted sequencing of ABCA7 identifies splicing, stop-gain and intronic risk variants for Alzheimer disease.
Kunkle, BW., et al.
2017,  
Stroke
Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study.
Pase, MP., et al.
2017,  
Bioinformatics (Oxford, England)
Introducing COCOS: codon consequence scanner for annotating reading frame changes induced by stop-lost and frame shift variants.
Butkiewicz, M., et al.
2017,  
Neurobiology of aging
Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN, TMEM106B, ABCC9, and KCNMB2.
Katsumata, Y., et al.
2017,  
Nature communications
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.
McLaughlin, RL., et al.
2017,  
PLoS medicine
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
Desikan, RS., et al.
2017,  
PLoS medicine
Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study.
Steele, NZR., et al.
2017,  
Neurology
Polygenic risk scores in familial Alzheimer disease.
Tosto, G., et al.
2017,  
Annals of neurology
Genetic variation at 16q24.2 is associated with small vessel stroke.
Traylor, M., et al.
2017,  
Neurology
Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia.
Westwood, AJ., et al.
2017,  
Neurology. Genetics
20th Workshop of the International Stroke Genetics Consortium, November 3-4, 2016, Milan, Italy: 2016.036 ISGC research priorities.
Woo, D., et al.
2017,  
American journal of human genetics
The Rare-Variant Generalized Disequilibrium Test for Association Analysis of Nuclear and Extended Pedigrees with Application to Alzheimer Disease WGS Data.
He, Z., et al.
2017,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.
Mez, J., et al.
2017,  
Journal of neurology, neurosurgery, and psychiatry
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases.
Ferrari, R., et al.
2017,  
American journal of human genetics
Erratum: The Rare-Variant Generalized Disequilibrium Test for Association Analysis of Nuclear and Extended Pedigrees with Application to Alzheimer Disease WGS Data.
He, Z., et al.
2017,  
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals.
Ighodaro, ET., et al.
2017,  
The Clinical neuropsychologist
Traumatic brain injury history is associated with earlier age of onset of Alzheimer disease.
LoBue, C., et al.
2017,  
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
Genomic variants, genes, and pathways of Alzheimer's disease: An overview.
Naj, AC.
2017,  
Nature communications
Novel genetic loci associated with hippocampal volume.
Hibar, DP., et al.
2017,  
Methods in molecular biology (Clifton, N.J.)
In Silico Identification of RNA Modifications from High-Throughput Sequencing Data Using HAMR.
Kuksa, PP., et al.
2017,  
Alzheimer disease and associated disorders
Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology.
Monsell, SE., et al.
2017,  
Journal of Alzheimer's disease : JAD
Risk Factors and Pathological Substrates Associated with Agitation/Aggression in Alzheimer's Disease: A Preliminary Study using NACC Data.
Sennik, S., et al.
2017,  
Journal of Alzheimer's disease : JAD
The Correlation between Inflammatory Biomarkers and Polygenic Risk Score in Alzheimer's Disease.
Morgan, AR., et al.
2017,  
Journal of Alzheimer's disease : JAD
A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains.
Haddick, PCG., et al.
2017,  
Journal of Alzheimer's disease : JAD
Implication of the APP Gene in Intellectual Abilities.
Myrum, C., et al.
2017,  
Journal of Alzheimer's disease : JAD
Genetically-Predicted Adult Height and Alzheimer's Disease.
Larsson, SC., et al.
2017,  
PloS one
Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants.
Rehker, J., et al.
2017,  
NPJ systems biology and applications
Integrative gene network analysis identifies key signatures, intrinsic networks and host factors for influenza virus A infections.
Forst, CV., et al.
2017,  
Current Alzheimer research
Clinical and Environmental Correlates of Serum BDNF: A Descriptive Study with Plausible Implications for AD Research.
Weinstein, G., et al.
2017,  
PloS one
Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study.
Simino, J., et al.
2017,  
Journal of Alzheimer's disease : JAD
Methionine Sulfoxide Reductase-B3 (MsrB3) Protein Associates with Synaptic Vesicles and its Expression Changes in the Hippocampi of Alzheimer's Disease Patients.
Adams, SL., et al.
2016
2016,  
Acta neuropathologica
Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging.
Nelson, PT., et al.
2016,  
Neurology
Genetically decreased vitamin D and risk of Alzheimer disease.
Mokry, LE., et al.
2016,  
Annals of clinical and translational neurology
Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases.
Gagliano, SA., et al.
2016,  
European journal of human genetics : EJHG
SORL1 variants across Alzheimer's disease European American cohorts.
Fernández, MV., et al.
2016,  
Nature neuroscience
Novel genetic loci underlying human intracranial volume identified through genome-wide association.
Adams, HHH., et al.
2016,  
Translational psychiatry
Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions.
Hill, WD., et al.
2016,  
Molecular and cellular probes
Genomics of Alzheimer's disease: Value of high-throughput genomic technologies to dissect its etiology.
Tosto, G.
2016,  
Neurology. Genetics
SORL1 mutations in early- and late-onset Alzheimer disease.
Cuccaro, ML., et al.
2016,  
Molecular psychiatry
Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
Herold, C., et al.
2016,  
BMC neurology
Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40.
Deming, Y., et al.
2016,  
BMC systems biology
DGCA: A comprehensive R package for Differential Gene Correlation Analysis.
McKenzie, AT., et al.
2016,  
Neurobiology of aging
ABCA7 p.G215S as potential protective factor for Alzheimer's disease.
Sassi, C., et al.
2016,  
JAMA neurology
The Role of Cardiovascular Risk Factors and Stroke in Familial Alzheimer Disease.
Tosto, G., et al.
2016,  
Molecular psychiatry
Assessing the genetic overlap between BMI and cognitive function.
Marioni, RE., et al.
2016,  
PLoS genetics
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.
Jakobsdottir, J., et al.
2016,  
Neurology
Incident parkinsonism in older adults without Parkinson disease.
Buchman, AS., et al.
2016,  
Annals of clinical and translational neurology
Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease.
Bonham, LW., et al.
2016,  
Nature genetics
NEK1 variants confer susceptibility to amyotrophic lateral sclerosis.
Kenna, KP., et al.
2016,  
Molecular neurobiology
PLD3 in Alzheimer's Disease: a Modest Effect as Revealed by Updated Association and Expression Analyses.
Zhang, D., et al.
2016,  
Journal of neurology, neurosurgery, and psychiatry
Traumatic brain injury history is associated with earlier age of onset of frontotemporal dementia.
LoBue, C., et al.
2016,  
Biological psychiatry
Genetic Markers of Human Evolution Are Enriched in Schizophrenia.
Srinivasan, S., et al.
2016,  
Acta neuropathologica
Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci.
Allen, M., et al.
2016,  
Bioinformatics (Oxford, England)
Pathway analysis by randomization incorporating structure-PARIS: an update.
Butkiewicz, M., et al.
2016,  
Nature genetics
Detection and interpretation of shared genetic influences on 42 human traits.
Pickrell, JK., et al.
2016,  
European journal of human genetics : EJHG
Evaluation of power of the Illumina HumanOmni5M-4v1 BeadChip to detect risk variants for human complex diseases.
Xing, C., et al.
2016,  
The New England journal of medicine
Incidence of Dementia over Three Decades in the Framingham Heart Study.
Satizabal, C., et al.
2016,  
Journal of Alzheimer's disease : JAD
Association of Physical Function with Clinical and Subclinical Brain Disease: The Framingham Offspring Study.
Camargo, EC., et al.
2016,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.
Allen, GI., et al.
2016,  
JAMA neurology
Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease.
Yokoyama, JS., et al.
2016,  
JAMA neurology
Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults.
Risacher, SL., et al.
2016,  
Neurology. Genetics
ABCA7 frameshift deletion associated with Alzheimer disease in African Americans.
Cukier, HN., et al.
2016,  
Science translational medicine
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.
Scott, RA., et al.
2016,  
BMC genomics
Genome-wide association study of prolactin levels in blood plasma and cerebrospinal fluid.
Staley, LA., et al.
2016,  
BMC genomics
Variants in ACPP are associated with cerebrospinal fluid Prostatic Acid Phosphatase levels.
Staley, LA., et al.
2016,  
BMC genomics
Variants in CCL16 are associated with blood plasma and cerebrospinal fluid CCL16 protein levels.
Ebbert, MTW., et al.
2016,  
The Lancet. Neurology
Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies.
2016,  
Journal of Alzheimer's disease : JAD
Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease.
Chouraki, V., et al.
2016,  
BMC bioinformatics
A comprehensive database of high-throughput sequencing-based RNA secondary structure probing data (Structure Surfer).
Berkowitz, ND., et al.
2016,  
Neurobiology of aging
Assessment of the genetic variance of late-onset Alzheimer's disease.
Ridge, PG., et al.
2016,  
Neurobiology of aging
The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.
Mez, J., et al.
2016,  
Genome medicine
Identification of the BRD1 interaction network and its impact on mental disorder risk.
Fryland, T., et al.
2016,  
Stroke
Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia.
Pase, MP., et al.
2016,  
Neurobiology of aging
The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume.
Lupton, MK., et al.
2016,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.
Hohman, TJ., et al.
2016,  
Neurology
Neuropathologic comorbidity and cognitive impairment in the Nun and Honolulu-Asia Aging Studies.
White, LR., et al.
2016,  
Annals of translational medicine
Toward precision medicine in Alzheimer's disease.
Reitz, C.
2016,  
European journal of neurology
Interleukin-6, interleukin-6 receptor gene variant, small-vessel disease and incident dementia.
Miwa, K., et al.
2016,  
Neurology
Low-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration.
Malik, R., et al.
2016,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk.
Ebbert, MTW., et al.
2016,  
Neurobiology of aging
Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium.
Hohman, TJ., et al.
2016,  
Neurology. Genetics
Segregation of a rare TTC3 variant in an extended family with late-onset Alzheimer disease.
Kohli, MA., et al.
2016,  
BMC genetics
Family-based approaches: design, imputation, analysis, and beyond.
Wijsman, EM.
2016,  
Molecular psychiatry
GWAS for executive function and processing speed suggests involvement of the CADM2 gene.
Ibrahim-Verbaas, CA., et al.
2016,  
Stroke
Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2.
Cheng, Y., et al.
2016,  
The New England journal of medicine
Incidence of Dementia over Three Decades in the Framingham Heart Study.
Satizabal, CL., et al.
2016,  
PLoS genetics
Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.
Choi, SH., et al.
2016,  
BMC proceedings
Estimating relationships between phenotypes and subjects drawn from admixed families.
Blue, EM., et al.
2016,  
Alzheimer's & dementia (Amsterdam, Netherlands)
Plasma clusterin levels and risk of dementia, Alzheimer's disease, and stroke.
Weinstein, G., et al.
2016,  
Neurobiology of aging
A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin.
Deming, Y., et al.
2016,  
Nucleic acids research
DASHR: database of small human noncoding RNAs.
Leung, YY., et al.
2016,  
Scientific reports
Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits.
Deming, Y., et al.
2016,  
Molecular psychiatry
A novel Alzheimer disease locus located near the gene encoding tau protein.
Jun, G., et al.
2016,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.
Kunkle, BW., et al.
2016,  
Current protocols in human genetics
In Silico Functional Annotation of Genomic Variation.
Butkiewicz, M.
2016,  
Alzheimer disease and associated disorders
Diabetic Phenotypes and Late-Life Dementia Risk: A Mechanism-specific Mendelian Randomization Study.
Walter, S., et al.
2016,  
Journal of Alzheimer's disease : JAD
Self-Reported Traumatic Brain Injury and Mild Cognitive Impairment: Increased Risk and Earlier Age of Diagnosis.
LoBue, C., et al.
2016,  
PloS one
Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.
Karch, CM., et al.
2016,  
PloS one
Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease.
Sassi, C., et al.
2016,  
BMC proceedings
Identity-by-descent estimation with population- and pedigree-based imputation in admixed family data.
Saad, M., et al.
2015
2015,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.
Mukherjee, S., et al.
2015,  
Bioinformatics (Oxford, England)
PBAP: a pipeline for file processing and quality control of pedigree data with dense genetic markers.
Nato, AQ., et al.
2015,  
Molecular psychiatry
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.
Desikan, RS., et al.
2015,  
Experimental neurology
Drosophila and experimental neurology in the post-genomic era.
Shulman, JM.
2015,  
Brain : a journal of neurology
Common polygenic variation enhances risk prediction for Alzheimer's disease.
Escott-Price, V., et al.
2015,  
Neurology
Dipping to clear amyloid: Cerebrovascular reactivity and neurodegeneration--cause or effect?
Seshadri, S.
2015,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.
Barral, S., et al.
2015,  
Future neurology
Novel susceptibility loci for Alzheimer's disease.
Reitz, C.
2015,  
Neurobiology of aging
Genetic variants associated with susceptibility to psychosis in late-onset Alzheimer's disease families.
Barral, S., et al.
2015,  
JAMA neurology
Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.
Ghani, M., et al.
2015,  
Nature genetics
An atlas of genetic correlations across human diseases and traits.
Bulik-Sullivan, B., et al.
2015,  
Stroke
White Matter Lesion Progression: Genome-Wide Search for Genetic Influences.
Hofer, E., et al.
2015,  
JAMA psychiatry
Genetic Analysis of Association Between Calcium Signaling and Hippocampal Activation, Memory Performance in the Young and Old, and Risk for Sporadic Alzheimer Disease.
Heck, A., et al.
2015,  
Annals of neurology
Rare coding mutations identified by sequencing of Alzheimer disease genome-wide association studies loci.
Vardarajan, BN., et al.
2015,  
Annals of clinical and translational neurology
F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease.
Tosto, G., et al.
2015,  
Neurology. Genetics
Late-onset Alzheimer disease risk variants mark brain regulatory loci.
Allen, M., et al.
2015,  
JAMA neurology
Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project.
Auer, PL., et al.
2015,  
Nature
Directional dominance on stature and cognition in diverse human populations.
Joshi, PK., et al.
2015,  
Human molecular genetics
Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.
Malik, M., et al.
2015,  
PLoS medicine
Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.
Østergaard, SD., et al.
2015,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Convergent genetic and expression data implicate immunity in Alzheimer's disease.
2015,  
Circulation
Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.
Desikan, RS., et al.
2015,  
Journal of computational biology : a journal of computational molecular cell biology
PASTA: Ultra-Large Multiple Sequence Alignment for Nucleotide and Amino-Acid Sequences.
Mirarab, S., et al.
2015,  
Bioinformatics (Oxford, England)
HIPPIE: a high-throughput identification pipeline for promoter interacting enhancer elements.
Hwang, Y., et al.
2015,  
Nature
Common genetic variants influence human subcortical brain structures.
Hibar, DP., et al.
2015,  
Biological psychiatry
Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
Debette, S., et al.
2015,  
Circulation. Cardiovascular genetics
Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.
Verhaaren, BFJ., et al.
2015,  
Neurobiology of aging
Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.
Chauhan, G., et al.
2015,  
Nature
PLD3 variants in population studies.
van der Lee, SJ., et al.
2015,  
Annals of neurology
Protective variant for hippocampal atrophy identified by whole exome sequencing.
Nho, K., et al.
2015,  
Neurology
PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease.
Beecham, GW., et al.
2015,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Plasma amyloid-β and risk of Alzheimer's disease in the Framingham Heart Study.
Chouraki, V., et al.
2015,  
Neurobiology of aging
NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases.
Nalls, MA., et al.
2015,  
Age and ageing
APOE and mild cognitive impairment: the Framingham Heart Study.
Jefferson, AL., et al.
2015,  
Genome research
Actionable exomic incidental findings in 6503 participants: challenges of variant classification.
Amendola, LM., et al.
2015,  
Neurology
Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease.
Rannikmäe, K., et al.
2015,  
Annals of neurology
Coding mutations in SORL1 and Alzheimer disease.
Vardarajan, BN., et al.
2015,  
JAMA neurology
Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
Wang, L., et al.
2015,  
Stroke
Genes from a translational analysis support a multifactorial nature of white matter hyperintensities.
Lopez, LM., et al.
2015,  
Molecular psychiatry
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).
Davies, G., et al.
2015,  
Nature
New genetic loci link adipose and insulin biology to body fat distribution.
Shungin, D., et al.
2015,  
Nature
Genetic studies of body mass index yield new insights for obesity biology.
Locke, AE., et al.
2015,  
Journal of neuropathology and experimental neurology
Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology.
Nelson, PT., et al.
2015,  
The journals of gerontology. Series A, Biological sciences and medical sciences
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
Broer, L., et al.
2015,  
PloS one
Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin.
Amlie-Wolf, A., et al.
2014
2014,  
Human molecular genetics
SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.
Ramirez, A., et al.
2014,  
Neurobiology of aging
Genetic variants in a 'cAMP element binding protein' (CREB)-dependent histone acetylation pathway influence memory performance in cognitively healthy elderly individuals.
Barral, S., et al.
2014,  
JAMA neurology
Common genetic variants on 6q24 associated with exceptional episodic memory performance in the elderly.
Barral, S., et al.
2014,  
Nature medicine
A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.
Wetzel-Smith, MK., et al.
2014,  
Human molecular genetics
Whole-exome imputation of sequence variants identified two novel alleles associated with adult body height in African Americans.
Du, M., et al.
2014,  
Human molecular genetics
Coding variants in TREM2 increase risk for Alzheimer's disease.
Jin, SC., et al.
2014,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.
Logue, MW., et al.
2014,  
JAMA neurology
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
Naj, AC., et al.
2014,  
The Journal of clinical investigation
Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease.
French, CR., et al.
2014,  
The New England journal of medicine
Inactivating mutations in NPC1L1 and protection from coronary heart disease.
Stitziel, NO., et al.
2014,  
PLoS genetics
Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.
Kauwe, JSK., et al.
2014,  
Nature
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
Perry, JR., et al.
2014,  
Nature genetics
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.
Nalls, MA., et al.
2014,  
Annals of neurology
PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation.
Jun, G., et al.
2014,  
PLoS genetics
Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
Beecham, GW., et al.
2014,  
American journal of human genetics
Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results.
Tabor, HK., et al.
2014,  
Genes
The impact of the human genome project on complex disease.
Bailey, JNC., et al.
2014,  
The New England journal of medicine
Loss-of-function mutations in APOC3, triglycerides, and coronary disease.
Crosby, J., et al.
2014,  
Neurobiology of aging
Search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways.
Logue, MW., et al.
2014,  
Neurobiology of aging
Missense variant in TREML2 protects against Alzheimer's disease.
Benitez, BA., et al.
2014,  
Molecular psychiatry
ATP5H/KCTD2 locus is associated with Alzheimer's disease risk.
Boada, M., et al.
2014,  
Journal of lipid research
Rare coding variation in paraoxonase-1 is associated with ischemic stroke in the NHLBI Exome Sequencing Project.
Kim, DS., et al.
2014,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Parkinsonism and distinct dementia patterns in a family with the MAPT R406W mutation.
Carney, RM., et al.
2014,  
Methods (San Diego, Calif.)
Using machine learning and high-throughput RNA sequencing to classify the precursors of small non-coding RNAs.
Ryvkin, P., et al.
2014,  
Biological psychiatry
Genetics of Alzheimer's disease in Caribbean Hispanic and African American populations.
Reitz, C.
2014,  
Biochemical pharmacology
Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease.
Bennett, DA., et al.
2014,  
Molecular psychiatry
Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility.
Li, M., et al.
2014,  
JAMA neurology
Age-specific incidence rates for dementia and Alzheimer disease in NIA-LOAD/NCRAD and EFIGA families: National Institute on Aging Genetics Initiative for Late-Onset Alzheimer Disease/National Cell Repository for Alzheimer Disease (NIA-LOAD/NCRAD) and Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA).
Vardarajan, BN., et al.
2014,  
Stroke
Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies.
Malik, R., et al.
2014,  
Stroke
Predicting stroke through genetic risk functions: the CHARGE Risk Score Project.
Ibrahim-Verbaas, CA., et al.
2014,  
Translational psychiatry
Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene.
Ruiz, A., et al.
2014,  
American journal of human genetics
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.
Lange, LA., et al.
2014,  
Nature
Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease.
Cruchaga, C., et al.
2014,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
Sherva, R., et al.
2014,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Association of plasma and cortical amyloid beta is modulated by APOE ε4 status.
Swaminathan, S., et al.
2014,  
Dementia and geriatric cognitive disorders
Estrogen receptor α variants affect age at onset of Alzheimer's disease in a multiethnic female cohort.
Janicki, SC., et al.
2014,  
PloS one
Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.
Pérez-Palma, E., et al.
2014,  
Journal of Alzheimer's disease : JAD
Ordered subset analysis of copy number variation association with age at onset of Alzheimer's disease.
Szigeti, K., et al.
2014,  
Acta neuropathologica
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
Nelson, PT., et al.
2014,  
Alzheimer's research & therapy
Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels.
Allen, M., et al.
2014,  
Neuroepidemiology
Calibrating longitudinal cognition in Alzheimer's disease across diverse test batteries and datasets.
Gross, AL., et al.
2014,  
PloS one
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.
Escott-Price, V., et al.
2013
2013,  
RNA (New York, N.Y.)
HAMR: high-throughput annotation of modified ribonucleotides.
Ryvkin, P., et al.
2013,  
Journal of the American Geriatrics Society
Cognitive dysfunction and greater visit-to-visit systolic blood pressure variability.
Epstein, NU., et al.
2013,  
Nature genetics
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Lambert, JC., et al.
2013,  
American journal of human genetics
Joint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia.
Rosenthal, EA., et al.
2013,  
Neurobiology of aging
Novel progranulin variants do not disrupt progranulin secretion and cleavage.
Karch, CM., et al.
2013,  
Neurobiology of aging
Exceptional memory performance in the Long Life Family Study.
Barral, S., et al.
2013,  
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
APOE genotype modifies the relationship between midlife vascular risk factors and later cognitive decline.
Bangen, KJ., et al.
2013,  
Alzheimer's & dementia : the journal of the Alzheimer's Association
Frontolimbic atrophy is associated with agitation and aggression in mild cognitive impairment and Alzheimer's disease.
Trzepacz, PT., et al.
2013,  
Bioinformatics (Oxford, England)
DRAW+SneakPeek: analysis workflow and quality metric management for DNA-seq experiments.
Lin, C., et al.
2013,  
The New England journal of medicine
TREM2 and neurodegenerative disease.
Reitz, C.
2013,  
Current protocols in human genetics
Analyzing copy number variation using SNP array data: protocols for calling CNV and association tests.
Lin, C., et al.
2013,  
Annals of human genetics
C9ORF72 intermediate repeat copies are a significant risk factor for Parkinson disease.
Nuytemans, K., et al.
2013,  
Nucleic acids research
CoRAL: predicting non-coding RNAs from small RNA-sequencing data.
Leung, YY., et al.
2013,  
JAMA neurology
Food for thought.
Blacker, D.
2013,  
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Subscale validation of the neuropsychiatric inventory questionnaire: comparison of Alzheimer's disease neuroimaging initiative and national Alzheimer's coordinating center cohorts.
Trzepacz, PT., et al.
2013,  
JAMA neurology
C9orf72 hexanucleotide repeat expansions in clinical Alzheimer disease.
Harms, M., et al.
2013,  
Brain imaging and behavior
Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.
Hibar, DP., et al.
2013,  
Nucleic acids research
High-throughput identification of long-range regulatory elements and their target promoters in the human genome.
Hwang, Y., et al.
2013,  
Neurobiology of aging
Repeat expansions in the C9ORF72 gene contribute to Alzheimer's disease in Caucasians.
Kohli, MA., et al.
2013,  
Translational psychiatry
Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).
Reitz, C., et al.
2013,  
Neurobiology of aging
Visual contrast sensitivity in Alzheimer's disease, mild cognitive impairment, and older adults with cognitive complaints.
Risacher, SL., et al.
2013,  
Neuron
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Cruchaga, C., et al.
2013,  
JAMA
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.
Reitz, C., et al.
2013,  
Biological psychiatry
Effect of complement CR1 on brain amyloid burden during aging and its modification by APOE genotype.
Thambisetty, M., et al.
2013,  
Annals of human genetics
Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.
Holton, P., et al.
2013,  
The New England journal of medicine
TREM2 variants in Alzheimer's disease.
Guerreiro, R., et al.
2013,  
Dementia and geriatric cognitive disorders
Aromatase variants modify risk for Alzheimer's disease in a multiethnic female cohort.
Janicki, SC., et al.
2013,  
PLoS genetics
The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriers.
Benitez, BA., et al.
2013,  
Multimodal brain image analysis : third International Workshop, MBIA 2013, held in conjunction with MICCAI 2013, Nagoya, Japan, September 22, 2013 : proceedings. MBIA (Workshop) (3rd : 2013 : Nagoya-shi, Japan)
A Graph-Based Integration of Multimodal Brain Imaging Data for the Detection of Early Mild Cognitive Impairment (E-MCI).
Kim, D., et al.
2013,  
PloS one
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
Miyashita, A., et al.
2013,  
PloS one
Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel.
Kim, S., et al.
2013,  
PloS one
Characterizing the role of brain derived neurotrophic factor genetic variation in Alzheimer's disease neurodegeneration.
Honea, RA., et al.
2013,  
PloS one
Analysis of nonlinear gene expression progression reveals extensive pathway and age-specific transitions in aging human brains.
Cao, K., et al.
2013,  
PloS one
Alzheimer's disease: analyzing the missing heritability.